Equipments Details
Description
5800 MALDI TOFTOF is used to obtain the masses of lipids, nucleic acids, peptides, proteins, and polymers ranging in molecular mass from 200 Da up to 100 kDa or more.
For analysis by MALDI, a sample is mixed or coated with an energy-absorbing matrix and then irradiated with a laser beam (typically a Nd:Yag laser).
Singly protonated (positive ionization mode) or deprotonated (negative ionization mode) molecular ions are formed and detected by a time-of-flight mass analyzer.
In addition the 5800 has MS/MS capabilities, aiding in the identification of analytes. The 5800 can also be used for molecular imaging of tissues or materials.
For analysis by MALDI, a sample is mixed or coated with an energy-absorbing matrix and then irradiated with a laser beam (typically a Nd:Yag laser).
Singly protonated (positive ionization mode) or deprotonated (negative ionization mode) molecular ions are formed and detected by a time-of-flight mass analyzer.
In addition the 5800 has MS/MS capabilities, aiding in the identification of analytes. The 5800 can also be used for molecular imaging of tissues or materials.
Details
| Name | Asset |
|---|
Research technique
- Proteomics and Mass Spectrometry
Fingerprint
Explore the research areas in which this equipment has been used. These labels are generated based on the related outputs. Together they form a unique fingerprint.
Research output
- 1 Article
-
Inefficient recruitment of DDX39B impedes prespliceosome assembly on FOXP3 introns
Nagasawa, C. K., Bailey, A. O., Russell, W. K. & Garcia-Blanco, M. A., Jun 17 2024, In: RNA. 30, 7, p. 824-838 15 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations
Projects
- 1 Completed
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A targeted proteomics and metabolomics mass spectrometry core facility at the University of Texas Medical Branch
Russell, W. (PI)
Cancer Prevention and Research Institute ( Award #RP190682)
8/31/19 → 5/31/25
Project: Research project