Equipments Details
Description
Ultra-high resolution (214,000 @ 1,000Da) MS coupled to a nano-UPLC. The Fusion is a high performance system that provide high resolution and high mass accuracy for analysis of compounds ranging from small molecules to proteins. They have become particularly popular for proteomics applications, namely the identification of proteins based on analysis of constituent peptides (termed the “bottom-up” method) or analysis of the original intact proteins (termed the “top-down” approach). The fusion offers three fragmentation modes; collision induced dissociation (CID), High energy collision dissociation (HCD), and electron transfer dissociation (ETD). In addition, the Fusion has MSn capabilities combined with the added functionality of electron transfer dissociation are powerful tools needed to resolve the site and type of PTM present.
Details
| Name | Fusion Orbitrap Tribrid Mass Spectrometer |
|---|---|
| Manufacturers | Planet Orbitrap |
Fingerprint
Explore the research areas in which this equipment has been used. These labels are generated based on the related outputs. Together they form a unique fingerprint.
Research output
- 2 Article
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Inefficient recruitment of DDX39B impedes prespliceosome assembly on FOXP3 introns
Nagasawa, C. K., Bailey, A. O., Russell, W. K. & Garcia-Blanco, M. A., Jul 2024, In: RNA. 30, 7, p. 824-838 15 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Alternative splicing of the SUMO1/2/3 transcripts affects cellular SUMOylation and produces functionally distinct SUMO protein isoforms
Acuña, M. L., García-Morin, A., Orozco-Sepúlveda, R., Ontiveros, C., Flores, A., Diaz, A. V., Gutiérrez-Zubiate, I., Patil, A. R., Alvarado, L. A., Roy, S., Russell, W. K. & Rosas-Acosta, G., Dec 2023, In: Scientific reports. 13, 1, 2309.Research output: Contribution to journal › Article › peer-review
Open Access15 Link opens in a new tab Scopus citations
Projects
- 1 Completed
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A targeted proteomics and metabolomics mass spectrometry core facility at the University of Texas Medical Branch
Russell, W. (PI)
Cancer Prevention and Research Institute ( Award #RP190682)
8/31/19 → 5/31/25
Project: Research project