Research Output

2020

Circulating levels of ATP is a biomarker of HIV cognitive impairment

Velasquez, S., Prevedel, L., Valdebenito, S., Gorska, A. M., Golovko, M., Khan, N., Geiger, J. & Eugenin, E. A., Jan 2020, In : EBioMedicine. 51, 102503.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Enhancing KCNQ channel activity improves neurobehavioral recovery after spinal cord injury

Wu, Z., Li, L., Xie, F., Xu, G., Dang, D. & Yang, Q., Apr 1 2020, In : Journal of Pharmacology and Experimental Therapeutics. 373, 1, p. 72-80 9 p.

Research output: Contribution to journalArticle

HIV-1 Tat: Role in Bystander Toxicity

Ajasin, D. & Eugenin, E. A., Feb 25 2020, In : Frontiers in Cellular and Infection Microbiology. 10, 61.

Research output: Contribution to journalReview article

Open Access

HIV gp120 Protein Increases the Function of Connexin 43 Hemichannels and Pannexin-1 Channels in Astrocytes: Repercussions on Astroglial Function

Gajardo-Gómez, R., Santibañez, C. A., Labra, V. C., Gómez, G. I., Eugenin, E. A. & Orellana, J. A., Apr 3 2020, In : International journal of molecular sciences. 21, 7

Research output: Contribution to journalArticle

Open Access

Increased talin–vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections

Liu, Y., Xiao, J., Zhang, B., Shelite, T. R., Su, Z., Chang, Q., Judy, B., Li, X., Drelich, A., Bei, J., Zhou, Y., Zheng, J., Jin, Y., Rossi, S. L., Tang, S. J., Wakamiya, M., Saito, T., Ksiazek, T., Kaphalia, B. & Gong, B., Jan 1 2020, (Accepted/In press) In : Laboratory Investigation.

Research output: Contribution to journalArticle

Open Access

In Vivo Epithelial Metabolic Imaging Using a Topical Fluorescent Glucose Analog

Villarreal, P., Pal, R. & Vargas, G., Jan 1 2020, Methods in Molecular Biology. Humana Press Inc., p. 21-31 11 p. (Methods in Molecular Biology; vol. 2126).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Low-intensity, Kilohertz Frequency Spinal Cord Stimulation Differently Affects Excitatory and Inhibitory Neurons in the Rodent Superficial Dorsal Horn

Lee, K. Y., Bae, C., Lee, D., Kagan, Z., Bradley, K., Chung, J. M. & La, J. H., Jan 21 2020, In : Neuroscience. 428, p. 132-139 8 p.

Research output: Contribution to journalArticle

Open Access

Nucleolin mediates the binding of cancer cells to L-selectin under conditions of lymphodynamic shear stress

Goldson, T. M., Turner, K. L., Huang, Y., Carlson, G. E., Caggiano, E. G., Oberhauser, A. F., Fennewald, S. M., Burdick, M. M. & Resto, V. A., Jan 1 2020, In : American Journal of Physiology - Cell Physiology. 318, 1, p. C83-C93

Research output: Contribution to journalArticle

1 Scopus citations

Penetration of ibrexafungerp (formerly SCY-078) at the site of infection in an intra-abdominal candidiasis mouse model

Lee, A., Prideaux, B., Zimmerman, M., Carter, C., Barat, S., Angulo, D., Dartois, V., Perlin, D. S. & Zhao, Y., Jan 1 2020, In : Antimicrobial Agents and Chemotherapy. 64, 3, e02268.

Research output: Contribution to journalArticle

1 Scopus citations

Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4+ T cell recovery can harbor replication-competent HIV despite viral suppression

Real, F., Capron, C., Sennepin, A., Arrigucci, R., Zhu, A., Sannier, G., Zheng, J., Xu, L., Massé, J. M., Greffe, S., Cazabat, M., Donoso, M., Delobel, P., Izopet, J., Eugenin, E., Gennaro, M. L., Rouveix, E., Bordé, E. C. & Bomsel, M., Mar 18 2020, In : Science Translational Medicine. 12, 535, eaat6263.

Research output: Contribution to journalArticle

2 Scopus citations
2019

A Naturally Occurring Polymorphism in the HIV-1 Tat Basic Domain Inhibits Uptake by Bystander Cells and Leads to Reduced Neuroinflammation

Ruiz, A. P., Ajasin, D. O., Ramasamy, S., DesMarais, V., Eugenin, E. & Prasad, V. R., Dec 1 2019, In : Scientific reports. 9, 1, 3308.

Research output: Contribution to journalArticle

2 Scopus citations

Burn-Induced Impairment of Ileal Muscle Contractility Is Associated with Increased Extracellular Matrix Components

Cummins, C. B., Gu, Y., Wang, X., Lin, Y. M., Shi, X. Z. & Radhakrishnan, R. S., Jan 1 2019, (Accepted/In press) In : Journal of Gastrointestinal Surgery.

Research output: Contribution to journalArticle

Chronic poly-drug administration damages adult mouse brain neural stem cells

McGrath, E. L., Schlagal, C. R., Cortez, I., Dunn, T. J., Gao, J., Fox, R. G., Stutz, S. J., Kuo, Y. F., Hommel, J., Dineley, K., Cunningham, K., Kaphalia, B. & Wu, P., Nov 15 2019, In : Brain Research. 1723, 146425.

Research output: Contribution to journalArticle

Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies

Chen, Z., Gu, J., El Ayadi, A., Oberhauser, A., Zhou, J., Sousse, L., Finnerty, C., Herndon, D. & Boor, P. J., Jan 1 2019, In : Toxicology and Applied Pharmacology. 362, p. 9-19 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Efficacy of novel highly specific bromodomain-containing protein 4 inhibitors in innate inflammation–driven airway remodeling

Tian, B., Liu, Z., Litvinov, J., Maroto, R., Jamaluddin, M., Rytting, E., Patrikeev, I., Ochoa, L., Vargas, G., Motamedi, M., Ameredes, B., Zhou, J. & Brasier, A. R., Jan 1 2019, In : American Journal of Respiratory Cell and Molecular Biology. 60, 1, p. 68-83 16 p.

Research output: Contribution to journalArticle

8 Scopus citations

Electroacupuncture downregulates P2X3 receptor expression in dorsal root ganglia of the spinal nerve-ligated rat

Liang, Y., Gu, Y., Shi, R., Li, G., Chen, Y. & Huang, L-Y., Jan 1 2019, In : Molecular pain. 15

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Elevated human dipeptidyl peptidase 4 expression reduces the susceptibility of hDPP4 transgenic mice to middle east respiratory syndrome coronavirus infection and disease

Algaissi, A., Agrawal, A. S., Han, S., Peng, B., Luo, C., Li, F., Chan, T. S., Couch, R. B. & Tseng, C-T., Feb 15 2019, In : Journal of Infectious Diseases. 219, 5, p. 829-835 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis

He, X., Drelich, A., Yu, S., Chang, Q., Gong, D., Zhou, Y., Qu, Y., Yuan, Y., Su, Z., Qiu, Y., Tang, S-J., Gaitas, A., Ksiazek, T., Xu, Z., Zhou, J., Feng, Z., Wakamiya, M., Lu, F. & Gong, B., Mar 15 2019, In : Life Sciences. 221, p. 1-12 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Ferroptosis inhibitor SRS 16-86 attenuates ferroptosis and promotes functional recovery in contusion spinal cord injury

Zhang, Y., Sun, C., Zhao, C., Hao, J., Zhang, Y., Fan, B., Li, B., Duan, H., Liu, C., Kong, X., Wu, P., Yao, X. & Feng, S., Mar 1 2019, In : Brain Research. 1706, p. 48-57 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Fluoroquinolone efficacy against tuberculosis is driven by penetration into lesions and activity against resident bacterial populations

Sarathy, J., Blanc, L., Alvarez-Cabrera, N., O’Brien, P., Dias-Freedman, I., Mina, M., Zimmerman, M., Kaya, F., Liang, H. P. H., Prideaux, B., Dietzold, J., Salgame, P., Savic, R. M., Linderman, J., Kirschner, D., Pienaar, E. & Dartois, V., May 2019, In : Antimicrobial agents and chemotherapy. 63, 5, e02516-18.

Research output: Contribution to journalArticle

5 Scopus citations

Gap junctions coordinate the propagation of glycogenolysis induced by norepinephrine in the pineal gland

Eugenin, E. A., Valdebenito, S., Gorska, A. M., Martínez, A. D., Bitran, M. & Sáez, J. C., Dec 1 2019, In : Journal of neurochemistry. 151, 5, p. 558-569 12 p.

Research output: Contribution to journalArticle

HIV infection and latency induce a unique metabolic signature in human macrophages

Castellano, P., Prevedel, L., Valdebenito, S. & Eugenin, E., Dec 1 2019, In : Scientific reports. 9, 1, 3941.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Inhibition of LEF1-mediated DCLK1 by niclosamide attenuates colorectal cancer stemness

Park, S. Y., Kim, J. Y., Choi, J. H., Kim, J. H., Lee, C. J., Singh, P., Sarkar, S., Baek, J. H. & Nam, J. S., Feb 15 2019, In : Clinical Cancer Research. 25, 4, p. 1415-1429 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mass spectrometry imaging to detect lipid biomarkers and disease signatures in cancer

Holzlechner, M., Eugenin, E. & Prideaux, B., Dec 1 2019, In : Cancer Reports. 2, 6, e1229.

Research output: Contribution to journalReview article

Open Access

Maternal vaccination and protective immunity against Zika virus vertical transmission

Shan, C., Xie, X., Luo, H., Muruato, A. E., Liu, Y., Wakamiya, M., La, J. H., Chung, J. M., Weaver, S. C., Wang, T. & Shi, P. Y., Dec 1 2019, In : Nature communications. 10, 1, 5677.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Mechanical unfolding of spectrin reveals a super-exponential dependence of unfolding rate on force

Renn, J. P., Bhattacharyya, S., Bai, H., He, C., Li, H., Oberhauser, A. F., Marko, J. F., Makarov, D. E. & Matouschek, A., Jul 31 2019, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Microglia Mediate HIV-1 gp120-Induced Synaptic Degeneration in Spinal Pain Neural Circuits

Ru, W., Liu, X., Bae, C., Shi, Y., Walikonis, R., Mo Chung, J. & Tang, S. J., Oct 16 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 42, p. 8408-8421 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Morphine and HIV-1 gp120 cooperatively promote pathogenesis in the spinal pain neural circuit

Shi, Y., Yuan, S. & Tang, S-J., Jul 1 2019, In : Molecular pain. 15

Research output: Contribution to journalArticle

Open Access

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

Mitra, J., Guerrero, E. N., Hegde, P. M., Liachko, N. F., Wang, H., Vasquez, V., Gao, J., Pandey, A., Paul Taylor, J., Kraemer, B. C., Wu, P., Boldogh, I., Garruto, R. M., Mitra, S., Rao, K. S. & Hegde, M. L., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4696-4705 10 p.

Research output: Contribution to journalArticle

28 Scopus citations

Peripheral and central oxidative stress in chemotherapy-induced neuropathic pain

Shim, H. S., Bae, C., Wang, J., Lee, K. H., Hankerd, K. M., Kim, H. K., Chung, J. & La, J-H., Apr 1 2019, In : Molecular Pain. 15

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
Open Access
2 Scopus citations

The malaria toxin hemozoin induces apoptosis in human neurons and astrocytes: Potential role in the pathogenesis of cerebral malaria

Eugenin, E., Martiney, J. A. & Berman, J. W., Oct 1 2019, In : Brain Research. 1720, 146317.

Research output: Contribution to journalArticle

2 Scopus citations

The Relationship Between β-Endorphin and Experimental Pain Sensitivity in Older Adults With Knee Osteoarthritis

Ahn, H., La, J. H., Chung, J. M., Miao, H., Zhong, C., Kim, M., An, K., Lyon, D., Choi, E. & Fillingim, R. B., Jul 1 2019, In : Biological Research For Nursing. 21, 4, p. 400-406 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Tipsy neural stem cells: Chronic effects of alcohol on the brain

Schlagal, C. & Wu, P., Jan 1 2019, In : Neural Regeneration Research. 14, 1, p. 67-68 2 p.

Research output: Contribution to journalReview article

Tissue distribution and penetration of isavuconazole at the site of infection in experimental invasive aspergillosis in mice with underlying chronic granulomatous disease

Lee, A., Prideaux, B., Lee, M. H., Zimmerman, M., Dolgov, E., Perlin, D. S. & Zhao, Y., Jun 1 2019, In : Antimicrobial Agents and Chemotherapy. 63, 6, e00524-19.

Research output: Contribution to journalArticle

4 Scopus citations

Toll-like receptor 9 antagonism modulates astrocyte function and preserves proximal axons following spinal cord injury

Li, L., Ni, L., Eugenin, E., Heary, R. F. & Elkabes, S., Jan 1 2019, In : Brain, Behavior, and Immunity.

Research output: Contribution to journalArticle

3 Scopus citations

Viromimetic STING Agonist-Loaded Hollow Polymeric Nanoparticles for Safe and Effective Vaccination against Middle East Respiratory Syndrome Coronavirus

Lin, L. C. W., Huang, C. Y., Yao, B. Y., Lin, J. C., Agrawal, A., Algaissi, A., Peng, B. H., Liu, Y. H., Huang, P. H., Juang, R. H., Chang, Y. C., Tseng, C. T., Chen, H. W. & Hu, C. M. J., Jul 11 2019, In : Advanced Functional Materials. 29, 28, 1807616.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Activation of KCNQ Channels Prevents Paclitaxel-Induced Peripheral Neuropathy and Associated Neuropathic Pain

Li, L., Li, J., Zuo, Y., Dang, D., Frost, J. A. & Yang, Q., Jan 1 2018, (Accepted/In press) In : Journal of Pain.

Research output: Contribution to journalArticle

3 Scopus citations
9 Scopus citations

An Energy-efficient Wirelessly Powered Millimeter-scale Neurostimulator with Optimized Inductive Loop Antenna and Custom Rectifier

Lyu, H., Wang, J., La, J-H., Chung, J. & Babakhani, A., Aug 17 2018, Proceedings of the 2018 IEEE/MTT-S International Microwave Symposium, IMS 2018. Institute of Electrical and Electronics Engineers Inc., Vol. 2018-June. p. 1401-1404 4 p. 8439143

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)

Huang, H., Young, W., Chen, L., Feng, S., Zoubi, Z. M. A., Sharma, H. S., Saberi, H., Moviglia, G. A., He, X., Muresanu, D. F., Sharma, A., Otom, A., Andrews, R. J., Al-Zoubi, A., Bryukhovetskiy, A. S., Chernykh, E. R., Domańska-Janik, K., Jafar, E., Johnson, W. E., Li, Y. & 47 others, Li, D., Luan, Z., Mao, G., Shetty, A. K., Siniscalco, D., Skaper, S., Sun, T., Wang, Y., Wiklund, L., Xue, Q., You, S. W., Zheng, Z., Dimitrijevic, M. R., Masri, W. S. E., Sanberg, P. R., Xu, Q., Luan, G., Chopp, M., Cho, K. S., Zhou, X. F., Wu, P., Liu, K., Mobasheri, H., Ohtori, S., Tanaka, H., Han, F., Feng, Y., Zhang, S., Lu, Y., Zhang, Z., Rao, Y., Tang, Z., Xi, H., Wu, L., Shen, S., Xue, M., Xiang, G., Guo, X., Yang, X., Hao, Y., Hu, Y., Li, J., Ao, Q., Wang, B., Zhang, Z., Lu, M. & Li, T., Feb 1 2018, In : Cell Transplantation. 27, 2, p. 310-324 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Efficacy, Safety, and Feasibility of the Morphine Microdose Method in Community-Based Clinics

Wilkes, D., Orillosa, S. J., Hustak, E., Williams, C., Doulatram, G., Solanki, D. R., Garcia, E. A. & Huang, L-Y., Sep 1 2018, In : Pain medicine (Malden, Mass.). 19, 9, p. 1782-1789 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria

Wilson, K. D., Ochoa, L. F., Solomon, O. D., Pal, R., Cardona, S. M., Carpio, V. H., Keiser, P. H., Cardona, A. E., Vargas, G. & Stephens, R., Jun 4 2018, In : Journal of neuroinflammation. 15, 1, 173.

Research output: Contribution to journalArticle

5 Scopus citations

Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen

Nyon, M. P., Du, L., Tseng, C. T. K., Seid, C. A., Pollet, J., Naceanceno, K. S., Agrawal, A., Algaissi, A., Peng, B. H., Tai, W., Jiang, S., Bottazzi, M. E., Strych, U. & Hotez, P. J., Mar 27 2018, In : Vaccine. 36, 14, p. 1853-1862 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Exploring the combination of large area widefield fluorescence imaging with multiphoton microscopy in the detection of oral epithelial neoplasia

Pal, R., Villarreal, P., Brown, T., Qiu, S., McCammon, S. & Vargas, G., Jan 1 2018, Microscopy Histopathology and Analytics, MICROSCOPY 2018. OSA - The Optical Society, Vol. Part F89-MICROSCOPY 2018.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

High-resolution mapping of fluoroquinolones in TB rabbit lesions reveals specific distribution in immune cell types

Blanc, L., Daudelin, I. B., Podell, B. K., Chen, P. Y., Zimmerman, M., Martinot, A. J., Savic, R. M., Prideaux, B. & Dartois, V., Nov 1 2018, In : eLife. 7, e41115.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Human neural stem cell-derived neuron/astrocyte co-cultures respond to La Crosse virus infection with proinflammatory cytokines and chemokines

Dawes, B. E., Gao, J., Atkins, C., Nelson, J. T., Johnson, K., Wu, P. & Freiberg, A., Nov 15 2018, In : Journal of Neuroinflammation. 15, 1, 1 p.

Research output: Contribution to journalArticle

5 Scopus citations

Identification, Localization, and Quantification of HIV Reservoirs Using Microscopy

Prevedel, L., Ruel, N., Castellano, P., Smith, C., Malik, S., Villeux, C., Bomsel, M., Morgello, S. & Eugenin, E., Jan 1 2018, (Accepted/In press) In : Current Protocols in Cell Biology. e64.

Research output: Contribution to journalArticle

6 Scopus citations

Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing

Ochoa, L. F., Kholodnykh, A., Villarreal, P., Tian, B., Pal, R., Freiberg, A. N., Brasier, A. R., Motamedi, M. & Vargas, G., Dec 1 2018, In : Scientific reports. 8, 1, 13348.

Research output: Contribution to journalArticle

5 Scopus citations