Research Output

2016

Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: Identification of rifampicin as a neuroprotectant

López-García, I., Gero, D., Szczesny, B., Szoleczky, P., Olah, G., Modis, K., Zhang, K., Gao, J., Wu, P., Sowers, L., Dewitt, D., Prough, D. & Szabo, C., 2016, (Accepted/In press) In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

7 Scopus citations

Differential Responses of Human Fetal Brain Neural Stem Cells to Zika Virus Infection

McGrath, E. L., Rossi, S. L., Gao, J., Widen, S. G., Grant, A. C., Dunn, T. J., Azar, S. R., Roundy, C. M., Xiong, Y., Prusak, D. J., Loucas, B. D., Wood, T., Yu, Y., Fernández-Salas, I., Weaver, S. C., Vasilakis, N. & Wu, P., Jul 27 2016, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

51 Scopus citations

Dysregulation of Norepinephrine Release in the Absence of Functional Synaptotagmin 7

Shih, A. M., Varghese, L., Bittar, A., Park, S. H., Chung, J. & Shin, O. H., Jun 1 2016, In : Journal of Cellular Biochemistry. 117, 6, p. 1446-1453 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dysregulation of toll-like receptor 7 compromises innate and adaptive T cell responses and host resistance to an attenuated West Nile virus infection in old mice

Xie, G., Luo, H., Pang, L., Peng, B., Winkelmann, E., McGruder, B., Hesse, J., Whiteman, M., Campbell, G., Milligan, G., Cong, Y., Barrett, A. & Wang, T., 2016, In : Journal of Virology. 90, 3, p. 1333-1344 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Epac-protein kinase C alpha signaling in purinergic P2X3R-mediated hyperalgesia after inflammation

Gu, Y., Li, G., Chen, Y. & Huang, L-Y., Jul 1 2016, In : Pain. 157, 7, p. 1541-1550 10 p.

Research output: Contribution to journalArticle

19 Scopus citations

Epigenetic regulation of human DCLK-1 gene during coloncarcinogenesis: Clinical and mechanistic implications

Singh, P., O'Connell, M. & Shubhashish, S., Sep 1 2016, In : Stem Cell Investigation. 2016, SEP, 51.

Research output: Contribution to journalReview article

9 Scopus citations
11 Scopus citations

Giving new life to old lungs: Methods to produce and assess whole human paediatric bioengineered lungs

Nichols, J., La Francesca, S., Vega, S. P., Niles, J. A., Argueta, L. B., Riddle, M., Sakamoto, J., Vargas, G., Pal, R., Woodson, L., Rhudy, J., Lee, D., Seanor, D., Campbell, G., Schnadig, V. & Cortiella, J., 2016, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

22 Scopus citations

Human neural stem cell transplantation-mediated alteration of microglial/macrophage phenotypes after traumatic brain injury

Gao, J., Grill, R. J., Dunn, T. J., Bedi, S., Labastida, J. A., Hetz, R. A., Xue, H., Thonhoff, J. R., Dewitt, D., Prough, D., Cox, C. S. & Wu, P., 2016, In : Cell Transplantation. 25, 10, p. 1863-1877 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus

Agrawal, A. S., Tao, X., Algaissi, A., Garron, T., Narayanan, K., Peng, B. H., Couch, R. B. & Tseng, C. T. K., Sep 1 2016, In : Human Vaccines and Immunotherapeutics. 12, 9, p. 2351-2356 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Increased risk of death for patients on the waitlist for liver transplant residing at greater distance from specialized liver transplant centers in the USA

Cicalese, L., Shirafkan, A., Jennings, K., Zorzi, D. & Rastellini, C., Aug 3 2016, (Accepted/In press) In : Transplantation.

Research output: Contribution to journalArticle

9 Scopus citations

Interactions of opioids and HIV infection in the pathogenesis of chronic pain

Liu, B., Liu, X. & Tang, S-J., Feb 10 2016, In : Frontiers in Microbiology. 7, FEB, 103.

Research output: Contribution to journalArticle

15 Scopus citations

In vivo rectal mucosal barrier function imaging in a large-animal model by using confocal endomicroscopy: Implications for injury assessment and use in HIV prevention studies

Vargas, G., Vincent, K., Zhu, Y., Szafron, D., Brown, T. C., Villarreal, P. P., Bourne, N., Milligan, G. & Motamedib, M., Aug 1 2016, In : Antimicrobial Agents and Chemotherapy. 60, 8, p. 4600-4609 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Molecular Turbocharging Stem Cells to Improve Treatment of Experimental Spinal Cord Injury

Wu, P. & Prough, D., Mar 1 2016, In : Critical Care Medicine. 44, 3, p. 649-650 2 p.

Research output: Contribution to journalArticle

Oligodendrocytes in HIV-associated pain pathogenesis

Shi, Y., Shu, J., Liang, Z., Yuan, S. & Tang, S-J., Jun 1 2016, In : Molecular Pain. 12

Research output: Contribution to journalArticle

9 Scopus citations

Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus Infection

Agrawal, A. S., Ying, T., Tao, X., Garron, T., Algaissi, A., Wang, Y., Wang, L., Peng, B., Jiang, S., Dimitrov, D. S. & Tseng, C-T., Aug 19 2016, In : Scientific Reports. 6, 31629.

Research output: Contribution to journalArticle

31 Scopus citations

Remodeling of the epithelial-connective tissue interface in oral epithelial dysplasia as visualized by noninvasive 3D imaging

Pal, R., Shilagard, T., Yang, J., Villarreal, P., Brown, T., Qiu, S., McCammon, S., Resto, V. & Vargas, G., Aug 15 2016, In : Cancer Research. 76, 16, p. 4637-4647 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

Spatial and Sex-Dependent Responses of Adult Endogenous Neural Stem Cells to Alcohol Consumption

McGrath, E. L., Gao, J., Kuo, Y. F., Dunn, T. J., Ray, M. J., Dineley, K. T., Cunningham, K. A., Kaphalia, B. S. & Wu, P., Aug 7 2016, (Accepted/In press) In : Stem Cell Reports.

Research output: Contribution to journalArticle

4 Scopus citations

Spinal astrocytic activation contributes to mechanical allodynia in a rat model of cyclophosphamide-induced cystitis

Liu, B., Su, M., Tang, S-J., Zhou, X., Zhan, H., Yang, F., Li, W., Li, T. & Xie, J., Nov 1 2016, In : Molecular Pain. 12

Research output: Contribution to journalArticle

12 Scopus citations

Systems genetic and pharmacological analysis identifies candidate genes underlying mechanosensation in the von Frey test

Young, E. E., Bryant, C. D., Lee, S. E., Peng, X., Cook, B., Nair, H. K., Dreher, K. J., Zhang, X., Palmer, A. A., Chung, J. M., Mogil, J. S., Chesler, E. J. & Lariviere, W. R., Jul 1 2016, In : Genes, Brain and Behavior. 15, 6, p. 604-615 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
1 Scopus citations
2015

Antinociceptive effects of fisetin against diabetic neuropathic pain in mice: Engagement of antioxidant mechanisms and spinal GABAA receptors

Zhao, X., Li, X. L., Liu, X., Wang, C., Zhou, D. S., Ma, Q., Zhou, W. H. & Hu, Z. Y., Dec 1 2015, In : Pharmacological Research. 102, p. 286-297 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

A Wnt5a signaling pathway in the pathogenesis of HIV-1 gp120-induced pain

Yuan, S. B., Ji, G., Li, B., Andersson, T., Neugebauer, V. & Tang, S-J., Jul 1 2015, In : Pain. 156, 7, p. 1311-1319 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
8 Scopus citations

Dimeric organization of blood coagulation factor VIII bound to lipid nanotubes

Dalm, D., Galaz-Montoya, J. G., Miller, J. L., Grushin, K., Villalobos, A., Koyfman, A. Y., Schmid, M. F. & Stoilova-McPhie, S., Jun 17 2015, In : Scientific Reports. 5, 11212.

Research output: Contribution to journalArticle

7 Scopus citations

Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection

Yun, T., Park, A., Hill, T. E., Pernet, O., Beaty, S. M., Juelich, T. L., Smith, J. K., Zhang, L., Wang, Y. E., Vigant, F., Gao, J., Wu, P., Lee, B. & Freiberg, A. N., Jan 1 2015, In : Journal of virology. 89, 2, p. 1242-1253 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Factor VIII organisation on nanodiscs with different lipid composition

Grushin, K., Miller, J., Dalm, D. & Stoilova-McPhie, S., 2015, In : Thrombosis and Haemostasis. 113, 4, p. 741-749 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Generation of a transgenic mouse model of middle east respiratory syndrome coronavirus infection and disease

Agrawal, A. S., Garron, T., Tao, X., Peng, B. H., Wakamiya, M., Chan, T. S., Couch, R. B. & Tseng, C. T. K., Jan 1 2015, In : Journal of virology. 89, 7, p. 3659-3670 12 p.

Research output: Contribution to journalArticle

94 Scopus citations

Induction of chronic pancreatitis by pancreatic duct ligation activates BMP2, apelin, and PTHrP expression in mice

Rastellini, C., Han, S., Bhatia, V., Cao, Y., Liu, K., Gao, X., Ko, T. C., Greeley, G. H. & Falzon, M., Sep 1 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 309, 7, p. G554-G565

Research output: Contribution to journalArticle

3 Scopus citations

Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis

Kantara, C., O'Connell, M. R., Luthra, G., Gajjar, A., Sarkar, S., Ullrich, R. L. & Singh, P., Jan 31 2015, In : Laboratory Investigation. 95, 1, p. 100-112 13 p.

Research output: Contribution to journalArticle

40 Scopus citations

Noninvasive, optoacoustic detection and characterization of intra- and extracranial hematomas and cerebral hypoxia

Petrov, A., Prough, D., Petrov, Y., Petrov, I. Y., Robertson, C. S., Asokan, V., Agbor, A. & Esenaliev, R., 2015, Progress in Biomedical Optics and Imaging - Proceedings of SPIE. SPIE, Vol. 9323. 93233N

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity

Kantara, C., Moya, S. M., Houchen, C. W., Umar, S., Ullrich, R. L., Singh, P. & Carney, D. H., Nov 1 2015, In : Laboratory Investigation. 95, 11, p. 1222-1233 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Pancreatic islet APJ deletion reduces islet density and glucose tolerance in mice

Han, S., Englander, E., Gomez, G., Rastellini, C., Quertermous, T., Kundu, R. K. & Greeley, G. H., Jul 1 2015, In : Endocrinology. 156, 7, p. 2451-2460 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Quantification of Histone Modifications by Parallel-Reaction Monitoring: A Method Validation

Sowers, J. L., Mirfattah, B., Xu, P., Tang, H., Park, I. Y., Walker, C., Wu, P., Laezza, F., Sowers, L. C. & Zhang, K., Oct 6 2015, In : Analytical Chemistry. 87, 19, p. 10006-10014 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Reduced Incidence of Dementia in Solid Organ Transplant Patients Treated with Calcineurin Inhibitors

Taglialatela, G., Rastellini, C. & Cicalese, L., Jul 24 2015, In : Journal of Alzheimer's Disease. 47, 2, p. 329-333 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Role of intestinal myofibroblasts in HIV-associated intestinal collagen deposition and immune reconstitution following combination antiretroviral therapy

Asmuth, D. M., Pinchuk, I. V., Wu, J., Vargas, G., Chen, X., Mann, S., Albanese, A., Ma, Z. M., Saroufeem, R., Melcher, G. P., Troia-Cancio, P., Torok, N. J., Miller, C. J. & Powell, D. W., May 15 2015, In : AIDS (London, England). 29, 8, p. 877-888 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Severe acute respiratory syndrome-associated coronavirus vaccines formulated with delta inulin adjuvants provide enhanced protection while ameliorating lung eosinophilic immunopathology

Honda-Okubo, Y., Barnard, D., Ong, C. H., Peng, B. H., Tseng, C. T. K. & Petrovsky, N., Jan 1 2015, In : Journal of virology. 89, 6, p. 2995-3007 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Single mechanically-gated cation channel currents can trigger action potentials in neocortical and hippocampal pyramidal neurons

Nikolaev, Y. A., Dosen, P. J., Laver, D. R., Van Helden, D. F. & Hamill, O. P., May 22 2015, In : Brain Research. 1608, p. 1-13 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Thermally-induced structural changes in an armadillo repeat protein suggest a novel thermosensor mechanism in a molecular chaperone

Bujalowski, P. J., Nicholls, P., Barral, J. M. & Oberhauser, A. F., Feb 2 2015, In : FEBS Letters. 589, 1, p. 123-130 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Total pancreatectomy with islet autotransplantation summary of an NIDDK workshop

Bellin, M. D., Gelrud, A., Arreaza-Rubin, G., Dunn, T. B., Humar, A., Morgan, K. A., Naziruddin, B., Rastellini, C., Rickels, M. R., Schwarzenberg, S. J. & Andersen, D. K., Jan 1 2015, In : Annals of surgery. 261, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
2014

Acinar cell-specific knockout of the PTHrP gene decreases the proinflammatory and profibrotic responses in pancreatitis

Bhatia, V., Rastellini, C., Han, S., Aronson, J. F., Greeley, G. H. & Falzon, M., Sep 1 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 307, 5, p. G533-G549

Research output: Contribution to journalArticle

12 Scopus citations

Cationic lipid guided short-hairpin RNA interference of annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model

Andey, T., Marepally, S., Patel, A., Jackson, T., Sarkar, S., O'Connell, M., Reddy, R. C., Chellappan, S., Singh, P. & Singh, M., Jun 28 2014, In : Journal of Controlled Release. 184, 1, p. 67-78 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain

Kim, Y. S., Chu, Y., Han, L., Li, M., Li, Z., LaVinka, P. C., Sun, S., Tang, Z., Park, K., Caterina, M. J., Ren, K., Dubner, R., Wei, F. & Dong, X., Feb 19 2014, In : Neuron. 81, 4, p. 873-887 15 p.

Research output: Contribution to journalArticle

121 Scopus citations

Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke

Nicholls, P., Bujalowski, P. J., Epstein, H. F., Boehning, D. F., Barral, J. M. & Oberhauser, A. F., Nov 3 2014, In : FEBS Letters. 588, 21, p. 3977-3981 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA

Kantara, C., O'Connell, M., Sarkar, S., Moya, S., Ullrich, R. & Singh, P., Jan 5 2014, In : Cancer Research. 74, 9, p. 2487-2498 12 p.

Research output: Contribution to journalArticle

70 Scopus citations

Ethanol suppresses PGC-1α expression by interfering with the cAMP-CREB pathway in neuronal cells

Liu, Z., Liu, Y., Gao, R., Li, H., Dunn, T., Wu, P., Smith, R. G., Sarkar, P. S. & Fang, X., Aug 6 2014, In : PloS one. 9, 8, e104247.

Research output: Contribution to journalArticle

14 Scopus citations

Evaluation of INK4A promoter methylation using pyrosequencing and circulating cell-free DNA from patients with hepatocellular carcinoma

Huang, G., Krocker, J. D., Kirk, J. L., Merwat, S. N., Ju, H., Soloway, R. D., Wieck, L. R., Li, A., Okorodudu, A. O., Petersen, J. R., Abdulla, N. E., Duchini, A., Cicalese, L., Rastellini, C., Hu, P. C. & Dong, J., Jun 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 6, p. 899-909 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Exocytosis and synaptic vesicle function

Shin, O. H., 2014, In : Comprehensive Physiology. 4, 1, p. 149-175 27 p.

Research output: Contribution to journalArticle

31 Scopus citations

Gp120 in the pathogenesis of human immunodeficiency virus-associated pain

Yuan, S. B., Shi, Y., Chen, J., Zhou, X., Li, G., Gelman, B. B., Lisinicchia, J. G., Carlton, S. M., Ferguson, M. R., Tan, A., Sarna, S. K. & Tang, S. J., Jun 2014, In : Annals of Neurology. 75, 6, p. 837-850 14 p.

Research output: Contribution to journalArticle

36 Scopus citations

Helical organization of blood coagulation factor VIII on lipid nanotubes

Miller, J., Dalm, D., Koyfman, A. Y., Grushin, K. & Stoilova-McPhie, S., Jun 3 2014, In : Journal of Visualized Experiments. 88, e51254.

Research output: Contribution to journalArticle

6 Scopus citations