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2017

Nucleoside reverse transcriptase inhibitors (NRTIs) induce proinflammatory cytokines in the CNS via Wnt5a signaling

Wu, T., Zhang, J., Geng, M., Tang, S. J., Zhang, W. & Shu, J., Dec 1 2017, In : Scientific reports. 7, 1, 4117.

Research output: Contribution to journalArticle

9 Scopus citations

Pathogenesis of abdominal pain in bowel obstruction: Role of mechanical stress-induced upregulation of nerve growth factor in gut smooth muscle cells

Lin, Y. M., Fu, Y., Winston, J., Radhakrishnan, R., Sarna, S. K., Huang, L-Y. & Shi, X-Z., Apr 1 2017, In : Pain. 158, 4, p. 583-592 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
5 Scopus citations

Potential role of phase separation of repetitive DNA in chromosomal organization

Tang, S. J., Oct 18 2017, In : Genes. 8, 10, 279.

Research output: Contribution to journalArticle

9 Scopus citations

PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease

Hsu, W. C. J., Wildburger, N. C., Haidacher, S. J., Nenov, M. N., Folorunso, O., Singh, A. K., Chesson, B. C., Franklin, W. F., Cortez, I., Sadygov, R. G., Dineley, K. T., Rudra, J. S., Taglialatela, G., Lichti, C. F., Denner, L. & Laezza, F., Sep 2017, In : Experimental Neurology. 295, p. 1-17 17 p.

Research output: Contribution to journalArticle

18 Scopus citations

Reactive oxygen species affect spinal cell type-specific synaptic plasticity in a model of neuropathic pain

Bittar, A., Jun, J., La, J. H., Wang, J., Leem, J. W. & Chung, J. M., Nov 1 2017, In : Pain. 158, 11, p. 2137-2146 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Redefining 3Dimensional placental membrane microarchitecture using multiphoton microscopy and optical clearing

Richardson, L., Vargas, G., Brown, T., Ochoa, L., Trivedi, J., Kacerovský, M., Lappas, M. & Menon, R., May 1 2017, In : Placenta. 53, p. 66-75 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Reversible stacking of lipid nanodiscs for structural studies of clotting factors

Grushin, K., White, M. A. & Stoilova-Mcphie, S., Feb 1 2017, In : Nanotechnology Reviews. 6, 1, p. 139-148 10 p.

Research output: Contribution to journalArticle

Role of Glypican-3 in the growth, migration and invasion of primary hepatocytes isolated from patients with hepatocellular carcinoma

Montalbano, M., Rastellini, C., McGuire, J. T., Prajapati, J., Shirafkan, A., Vento, R. & Cicalese, L., Dec 4 2017, (Accepted/In press) In : Cellular Oncology. p. 1-16 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Spatial and Sex-Dependent Responses of Adult Endogenous Neural Stem Cells to Alcohol Consumption

McGrath, E. L., Gao, J., Kuo, Y. F., Dunn, T. J., Ray, M. J., Dineley, K. T., Cunningham, K. A., Kaphalia, B. S. & Wu, P., Dec 12 2017, In : Stem Cell Reports. 9, 6, p. 1916-1930 15 p.

Research output: Contribution to journalArticle

4 Scopus citations
5 Scopus citations

Tau oligomers associate with inflammation in the brain and retina of tauopathy mice and in neurodegenerative diseases

Nilson, A. N., English, K. C., Gerson, J. E., Barton Whittle, T., Nicolas Crain, C., Xue, J., Sengupta, U., Castillo-Carranza, D. L., Zhang, W., Gupta, P. & Kayed, R., 2017, In : Journal of Alzheimer's Disease. 55, 3, p. 1083-1099 17 p.

Research output: Contribution to journalArticle

42 Scopus citations

Tau Oligomers in Sera of Patients with Alzheimer's Disease and Aged Controls

Kolarova, M., Sengupta, U., Bartos, A., Ricny, J. & Kayed, R., 2017, In : Journal of Alzheimer's Disease. 58, 2, p. 471-478 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

The glycosylation pathway is required for the secretion of Slit and for the maintenance of the Slit receptor Robo on axons

Manavalan, M. A., Jayasinghe, V. R., Grewal, R. & Bhat, K. M., Jun 20 2017, In : Science Signaling. 10, 484, eaam5841.

Research output: Contribution to journalArticle

4 Scopus citations

Unraveling drug penetration of echinocandin antifungals at the site of infection in an intra-abdominal abscess model

Zhao, Y., Prideaux, B., Nagasaki, Y., Lee, M. H., Chen, P. Y., Blanc, L., Ho, H., Clancy, C. J., Nguyen, M. H., Dartois, V. & Perlin, D. S., 2017, In : Antimicrobial agents and chemotherapy. 61, 10

Research output: Contribution to journalArticle

Open Access
27 Scopus citations
2018
9 Scopus citations

Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)

Huang, H., Young, W., Chen, L., Feng, S., Zoubi, Z. M. A., Sharma, H. S., Saberi, H., Moviglia, G. A., He, X., Muresanu, D. F., Sharma, A., Otom, A., Andrews, R. J., Al-Zoubi, A., Bryukhovetskiy, A. S., Chernykh, E. R., Domańska-Janik, K., Jafar, E., Johnson, W. E., Li, Y. & 47 others, Li, D., Luan, Z., Mao, G., Shetty, A. K., Siniscalco, D., Skaper, S., Sun, T., Wang, Y., Wiklund, L., Xue, Q., You, S. W., Zheng, Z., Dimitrijevic, M. R., Masri, W. S. E., Sanberg, P. R., Xu, Q., Luan, G., Chopp, M., Cho, K. S., Zhou, X. F., Wu, P., Liu, K., Mobasheri, H., Ohtori, S., Tanaka, H., Han, F., Feng, Y., Zhang, S., Lu, Y., Zhang, Z., Rao, Y., Tang, Z., Xi, H., Wu, L., Shen, S., Xue, M., Xiang, G., Guo, X., Yang, X., Hao, Y., Hu, Y., Li, J., Ao, Q., Wang, B., Zhang, Z., Lu, M. & Li, T., Feb 1 2018, In : Cell Transplantation. 27, 2, p. 310-324 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant

López-García, I., Gerő, D., Szczesny, B., Szoleczky, P., Olah, G., Módis, K., Zhang, K., Gao, J., Wu, P., Sowers, L. C., DeWitt, D., Prough, D. S. & Szabo, C., 2018, In : British Journal of Pharmacology. 175, 2, p. 284-300 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Efficacy, safety, and feasibility of the morphine microdose method in community-based clinics

Wilkes, D. M., Orillosa, S. J., Hustak, E. C., Williams, C. G., Doulatram, G. R., Solanki, D. R., Garcia, E. A. & Huang, L. Y. M., Sep 2018, In : Pain Medicine (United States). 19, 9, p. 1782-1789 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Elimination of intravascular thrombi prevents early mortality and reduces gliosis in hyper-inflammatory experimental cerebral malaria

Wilson, K. D., Ochoa, L. F., Solomon, O. D., Pal, R., Cardona, S. M., Carpio, V. H., Keiser, P. H., Cardona, A. E., Vargas, G. & Stephens, R., Jun 4 2018, In : Journal of neuroinflammation. 15, 1, 173.

Research output: Contribution to journalArticle

5 Scopus citations

Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen

Nyon, M. P., Du, L., Tseng, C. T. K., Seid, C. A., Pollet, J., Naceanceno, K. S., Agrawal, A., Algaissi, A., Peng, B. H., Tai, W., Jiang, S., Bottazzi, M. E., Strych, U. & Hotez, P. J., Mar 27 2018, In : Vaccine. 36, 14, p. 1853-1862 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

Extreme drug tolerance of mycobacterium tuberculosis in Caseum

Sarathy, J. P., Via, L. E., Weiner, D., Blanc, L., Boshoff, H., Eugenin, E. A., Barry, C. E. & Dartois, V. A., Feb 2018, In : Antimicrobial agents and chemotherapy. 62, 2, e02057-17.

Research output: Contribution to journalArticle

46 Scopus citations
5 Scopus citations

Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing

Ochoa, L. F., Kholodnykh, A., Villarreal, P., Tian, B., Pal, R., Freiberg, A. N., Brasier, A. R., Motamedi, M. & Vargas, G., Dec 1 2018, In : Scientific reports. 8, 1, 13348.

Research output: Contribution to journalArticle

9 Scopus citations

Inflammation induces Epac-protein kinase C alpha and epsilon signaling in TRPV1-mediated hyperalgesia

Gu, Y., Li, G. & Huang, L. Y. M., 2018, In : Pain. 159, 11, p. 2383-2393 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2 Scopus citations

Mitochondrial superoxide increases excitatory synaptic strength in spinal dorsal horn neurons of neuropathic mice

Bae, C., Wang, J., Shim, H. S., Tang, S. J., Chung, J. M. & La, J. H., Aug 1 2018, In : Molecular pain. 14

Research output: Contribution to journalArticle

5 Scopus citations

Nanoparticle Wettability Influences Nanoparticle-Phospholipid Interactions

Konduru, N. V., Damiani, F., Stoilova-Mcphie, S., Tresback, J. S., Pyrgiotakis, G., Donaghey, T. C., Demokritou, P., Brain, J. D. & Molina, R. M., Jun 5 2018, In : Langmuir. 34, 22, p. 6454-6461 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Neuron activity-induced Wnt signaling up-regulates expression of brain-derived neurotrophic factor in the pain neural circuit

Zhang, W., Shi, Y., Peng, Y., Zhong, L., Zhu, S., Zhang, W. & Tang, S. J., Oct 5 2018, In : Journal of Biological Chemistry. 293, 40, p. 15641-15651 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Induce Pathological Pain through Wnt5a-Mediated Neuroinflammation in Aging Mice

Yuan, S., Shi, Y., Guo, K. & Tang, S. J., Jun 1 2018, In : Journal of Neuroimmune Pharmacology. 13, 2, p. 230-236 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Oligodendrocyte differentiation from human neural stem cells: A novel role for c-Src

Wang, L., Schlagal, C. R., Gao, J., Hao, Y., Dunn, T. J., McGrath, E. L., Labastida, J. A., Yu, Y., Feng, S. Q., Liu, S. Y. & Wu, P., Nov 1 2018, In : Neurochemistry International. 120, p. 21-32 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Peli1 facilitates virus replication and promotes neuroinflammation during West Nile virus infection

Luo, H., Winkelmann, E. R., Zhu, S., Ru, W., Mays, E., Silvas, J. A., Vollmer, L. L., Gao, J., Peng, B. H., Bopp, N. E., Cromer, C., Shan, C., Xie, G., Li, G., Tesh, R., Popov, V. L., Shi, P. Y., Sun, S. C., Wu, P., Klein, R. S. & 4 others, Tang, S. J., Zhang, W., Aguilar, P. V. & Wang, T., Nov 1 2018, In : Journal of Clinical Investigation. 128, 11, p. 4980-4991 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Production and transplantation of bioengineered lung into a large-animal model

Nichols, J. E., La Francesca, S., Niles, J. A., Vega, S. P., Argueta, L. B., Frank, L., Christiani, D. C., Pyles, R. B., Himes, B. E., Zhang, R., Li, S., Sakamoto, J., Rhudy, J., Hendricks, G., Begarani, F., Liu, X., Patrikeev, I., Pal, R., Usheva, E., Vargas, G. & 7 others, Miller, A., Woodson, L. C., Wacher, A., Grimaldo, M., Weaver, D., Mlcak, R. & Cortiella, J., Aug 1 2018, In : Science Translational Medicine. 10, 452, eaao3926.

Research output: Contribution to journalArticle

31 Scopus citations

Quercetin attenuates AZT-induced neuroinflammation in the CNS

Yang, Y., Liu, X., Wu, T., Zhang, W., Shu, J., He, Y. & Tang, S. J., Dec 1 2018, In : Scientific reports. 8, 1, 6194.

Research output: Contribution to journalArticle

6 Scopus citations

Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations

Chen, B., Li, Y., Yu, B., Zhang, Z., Brommer, B., Williams, P. R., Liu, Y., Hegarty, S. V., Zhou, S., Zhu, J., Guo, H., Lu, Y., Zhang, Y., Gu, X. & He, Z., Jul 26 2018, In : Cell. 174, 3, p. 521-535.e13

Research output: Contribution to journalArticle

Open Access
27 Scopus citations
5 Scopus citations

The central domain of UNC-45 chaperone inhibits the myosin power stroke

Bujalowski, P. J., Nicholls, P., Garza, E. & Oberhauser, A. F., Jan 2018, In : FEBS Open Bio. 8, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging

Miller, R. E., Kim, Y. S., Tran, P. B., Ishihara, S., Dong, X., Miller, R. J. & Malfait, A. M., Jan 2018, In : Arthritis and Rheumatology. 70, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Zika virus infection of cultured human fetal brain neural stem cells for immunocytochemical analysis

McGrath, E. L., Gao, J. & Wu, P., Feb 5 2018, In : Journal of Visualized Experiments. 2018, 132, e56917.

Research output: Contribution to journalArticle

2019

Activation of KCNQ Channels Prevents Paclitaxel-Induced Peripheral Neuropathy and Associated Neuropathic Pain

Li, L., Li, J., Zuo, Y., Dang, D., Frost, J. A. & Yang, Q., May 2019, In : Journal of Pain. 20, 5, p. 528-539 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

A Highly Immunogenic, Protective, and Safe Adenovirus-Based Vaccine Expressing Middle East Respiratory Syndrome Coronavirus S1-CD40L Fusion Protein in a Transgenic Human Dipeptidyl Peptidase 4 Mouse Model

Hashem, A. M., Algaissi, A., Agrawal, A. S., Al-Amri, S. S., Alhabbab, R. Y., Sohrab, S. S., Almasoud, A. S., Alharbi, N. K., Peng, B. H., Russell, M., Li, X. & Tseng, C. T. K., Oct 8 2019, In : Journal of Infectious Diseases. 220, 10, p. 1558-1567 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

A Naturally Occurring Polymorphism in the HIV-1 Tat Basic Domain Inhibits Uptake by Bystander Cells and Leads to Reduced Neuroinflammation

Ruiz, A. P., Ajasin, D. O., Ramasamy, S., DesMarais, V., Eugenin, E. A. & Prasad, V. R., Dec 1 2019, In : Scientific reports. 9, 1, 3308.

Research output: Contribution to journalArticle

3 Scopus citations

Burn-Induced Impairment of Ileal Muscle Contractility Is Associated with Increased Extracellular Matrix Components

Cummins, C. B., Gu, Y., Wang, X., Lin, Y., Shi, X. Z. & Radhakrishnan, R. S., Jan 1 2019, (Accepted/In press) In : Journal of Gastrointestinal Surgery.

Research output: Contribution to journalArticle

Chronic poly-drug administration damages adult mouse brain neural stem cells

McGrath, E. L., Schlagal, C. R., Cortez, I., Dunn, T. J., Gao, J., Fox, R. G., Stutz, S. J., Kuo, Y. F., Hommel, J., Dineley, K., Cunningham, K., Kaphalia, B. & Wu, P., Nov 15 2019, In : Brain Research. 1723, 146425.

Research output: Contribution to journalArticle

Distinct roles of histamine H1-and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis

Shi, Z., Fultz, R. S., Engevik, M. A., Gao, C., Hall, A., Major, A., Mori-Akiyama, Y. & Versalovic, J., Jan 2019, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 316, 1, p. G205-G216

Research output: Contribution to journalArticle

2 Scopus citations

Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies

Chen, Z., Gu, J., El Ayadi, A., Oberhauser, A. F., Zhou, J., Sousse, L. E., Finnerty, C. C., Herndon, D. N. & Boor, P. J., Jan 1 2019, In : Toxicology and Applied Pharmacology. 362, p. 9-19 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Efficacy of novel highly specific bromodomain-containing protein 4 inhibitors in innate inflammation–driven airway remodeling

Tian, B., Liu, Z., Litvinov, J., Maroto, R., Jamaluddin, M., Rytting, E., Patrikeev, I., Ochoa, L., Vargas, G., Motamedi, M., Ameredes, B. T., Zhou, J. & Brasier, A. R., Jan 2019, In : American journal of respiratory cell and molecular biology. 60, 1, p. 68-83 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

Electroacupuncture downregulates P2X3 receptor expression in dorsal root ganglia of the spinal nerve-ligated rat

Liang, Y., Gu, Y., Shi, R., Li, G., Chen, Y. & Huang, L. Y. M., May 1 2019, In : Molecular pain. 15

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Elevated human dipeptidyl peptidase 4 expression reduces the susceptibility of hDPP4 transgenic mice to middle east respiratory syndrome coronavirus infection and disease

Algaissi, A., Agrawal, A. S., Han, S., Peng, B. H., Luo, C., Li, F., Chan, T. S., Couch, R. B. & Tseng, C. T. K., Feb 15 2019, In : Journal of Infectious Diseases. 219, 5, p. 829-835 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis

He, X., Drelich, A., Yu, S., Chang, Q., Gong, D., Zhou, Y., Qu, Y., Yuan, Y., Su, Z., Qiu, Y., Tang, S. J., Gaitas, A., Ksiazek, T., Xu, Z., Zhou, J., Feng, Z., Wakamiya, M., Lu, F. & Gong, B., Mar 15 2019, In : Life Sciences. 221, p. 1-12 12 p.

Research output: Contribution to journalArticle

2 Scopus citations