Biochemistry & Molecular Biology

Research Output

Filter
Review article
2020

Reserve genetic approaches for the development of Zika vaccines and therapeutics

Fontes-Garfias, C. R., Baker, C. K. & Shi, P. Y., Oct 2020, In : Current Opinion in Virology. 44, p. 7-15 9 p.

Research output: Contribution to journalReview article

Structural Insights Into How Proteoglycans Determine Chemokine-CXCR1/CXCR2 Interactions: Progress and Challenges

Rajarathnam, K. & Desai, U. R., Apr 24 2020, In : Frontiers in immunology. 11, 660.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

The dynamic life of virus capsids

Sherman, M. B., Smith, H. Q. & Smith, T. J., Jun 2020, In : Viruses. 12, 6, 618.

Research output: Contribution to journalReview article

Open Access

Understanding flavivirus capsid protein functions: The tip of the iceberg

Sotcheff, S. & Routh, A., Jan 2020, In : Pathogens. 9, 1, 42.

Research output: Contribution to journalReview article

Open Access
2019

4-Hydroxy-Trans-2-Nonenal in the Regulation of Anti-Oxidative and Pro-Inflammatory Signaling Pathways

Sonowal, H. & Ramana, K. V., 2019, In : Oxidative medicine and cellular longevity. 2019, 5937326.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Alternative polyadenylation of mRNA and its role in cancer

Yuan, F., Hankey, W., Wagner, E. J., Li, W. & Wang, Q., Jan 1 2019, (Accepted/In press) In : Genes and Diseases.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

A tale of two states: Normal and transformed, with and without rigidity sensing

Sheetz, M., Jan 1 2019, In : Annual Review of Cell and Developmental Biology. 35, p. 169-190 22 p.

Research output: Contribution to journalReview article

1 Scopus citations

Exploiting the legacy of the arbovirus hunters

Vasilakis, N., Tesh, R. B., Popov, V. L., Widen, S. G., Wood, T. G., Forrester, N. L., Gonzalez, J. P., Saluzzo, J. F., Alkhovsky, S., Lam, S. K., Mackenzie, J. S. & Walker, P. J., May 2019, In : Viruses. 11, 5, 471.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

How do chemokines navigate neutrophils to the target site: Dissecting the structural mechanisms and signaling pathways

Rajarathnam, K., Schnoor, M., Richardson, R. M. & Rajagopal, S., Feb 2019, In : Cellular Signalling. 54, p. 69-80 12 p.

Research output: Contribution to journalReview article

25 Scopus citations

Strategies for Zika drug discovery

Zou, J. & Shi, P. Y., Apr 2019, In : Current Opinion in Virology. 35, p. 19-26 8 p.

Research output: Contribution to journalReview article

12 Scopus citations

Switching Lifestyles Is an in vivo Adaptive Strategy of Bacterial Pathogens

Desai, S. K. & Kenney, L. J., Dec 11 2019, In : Frontiers in Cellular and Infection Microbiology. 9, 421.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

The dynamic capsid structures of the noroviruses

Smith, H. Q. & Smith, T. J., Mar 2019, In : Viruses. 11, 3, 235.

Research output: Contribution to journalReview article

Open Access
5 Scopus citations
Open Access
6 Scopus citations
2018

Did Zika Virus Mutate to Cause Severe Outbreaks?

Rossi, S. L., Ebel, G. D., Shan, C., Shi, P. Y. & Vasilakis, N., Oct 2018, In : Trends in Microbiology. 26, 10, p. 877-885 9 p.

Research output: Contribution to journalReview article

9 Scopus citations
11 Scopus citations

Glycosaminoglycan Interactions Fine-Tune Chemokine-Mediated Neutrophil Trafficking: Structural Insights and Molecular Mechanisms

Rajarathnam, K., Sepuru, K. M., Joseph, P. R. B., Sawant, K. V. & Brown, A. J., Apr 1 2018, In : Journal of Histochemistry and Cytochemistry. 66, 4, p. 229-239 11 p.

Research output: Contribution to journalReview article

10 Scopus citations

Potential Mechanisms for Enhanced Zika Epidemic and Disease

Xia, H., Xie, X., Shan, C. & Shi, P-Y., May 11 2018, In : ACS Infectious Diseases. 4, 5, p. 656-659 4 p.

Research output: Contribution to journalReview article

4 Scopus citations

SGLT2 Inhibitors and Cardiovascular Outcomes: Current Perspectives and Future Potentials

Jia, X., Mehta, P. B., Ye, Y., Alam, M., Birnbaum, Y. & Bajaj, M., Sep 1 2018, In : Current Diabetes Reports. 18, 9, 63.

Research output: Contribution to journalReview article

3 Scopus citations

The contribution of alternative polyadenylation to the cancer phenotype

Masamha, C. P. & Wagner, E., Jan 1 2018, In : Carcinogenesis. 39, 1, p. 2-10 9 p.

Research output: Contribution to journalReview article

14 Scopus citations
2017

Early history of circular RNAs, children of splicing

Pasman, Z. & Garcia-Blanco, M. A., Aug 3 2017, In : RNA Biology. 14, 8, p. 975-977 3 p.

Research output: Contribution to journalReview article

2 Scopus citations

Epigenetic regulation of noncoding RNA transcription by mammalian RNA polymerase III

Park, J. L., Lee, Y. S., Kunkeaw, N., Kim, S. Y., Kim, I. H. & Lee, Y. S., Feb 2017, In : Epigenomics. 9, 2, p. 171-187 17 p.

Research output: Contribution to journalReview article

10 Scopus citations

Regulation of chemokine function: The roles of GAG-binding and post-translational nitration

Thompson, S., Martínez-Burgo, B., Sepuru, K. M., Rajarathnam, K., Kirby, J. A., Sheerin, N. S. & Ali, S., Aug 3 2017, In : International journal of molecular sciences. 18, 8, 1692.

Research output: Contribution to journalReview article

11 Scopus citations

Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity

Awasthi, Y. C., Ramana, K. V., Chaudhary, P., Srivastava, S. K. & Awasthi, S., Oct 2017, In : Free Radical Biology and Medicine. 111, p. 235-243 9 p.

Research output: Contribution to journalReview article

17 Scopus citations

Signal and binding. I. Physico-chemical response to macromolecule–ligand interactions

Bujalowski, W., Jezewska, M. J. & Bujalowski, P., Mar 1 2017, In : Biophysical Chemistry. 222, p. 7-24 18 p.

Research output: Contribution to journalReview article

2 Scopus citations
2 Scopus citations

Small Molecules and Antibodies for Zika Therapy

Xie, X., Zou, J., Shan, C. & Shi, P. Y., 2017, In : Journal of Infectious Diseases. 216, p. S945-S950

Research output: Contribution to journalReview article

14 Scopus citations

The 5ʹ and 3ʹ untranslated regions of the flaviviral genome

Ng, W. C., Soto-Acosta, R., Bradrick, S. S., Garcia-Blanco, M. A. & Ooi, E. E., Jun 2017, In : Viruses. 9, 6, 137.

Research output: Contribution to journalReview article

43 Scopus citations

To ∼P or Not to ∼P? Non-canonical activation by two-component response regulators

Desai, S. K. & Kenney, L. J., Jan 1 2017, In : Molecular Microbiology. 103, 2, p. 203-213 11 p.

Research output: Contribution to journalReview article

Open Access
18 Scopus citations

Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network

Aliota, M. T., Bassit, L., Bradrick, S. S., Cox, B., Garcia-Blanco, M. A., Gavegnano, C., Friedrich, T. C., Golos, T. G., Griffin, D. E., Haddow, A. D., Kallas, E. G., Kitron, U., Lecuit, M., Magnani, D. M., Marrs, C., Mercer, N., McSweegan, E., Ng, L. F. P., O'Connor, D. H., Osorio, J. E. & 11 others, Ribeiro, G. S., Ricciardi, M., Rossi, S. L., Saade, G., Schinazi, R. F., Schott-Lerner, G. O., Shan, C., Shi, P. Y., Watkins, D. I., Vasilakis, N. & Weaver, S. C., Aug 2017, In : Antiviral research. 144, p. 223-246 24 p.

Research output: Contribution to journalReview article

60 Scopus citations
2016

Flavivirus RNA transactions from viral entry to genome replication

Garcia-Blanco, M., Vasudevan, S. G., Bradrick, S. & Nicchitta, C., Oct 1 2016, In : Antiviral Research. 134, p. 244-249 6 p.

Research output: Contribution to journalReview article

29 Scopus citations
24 Scopus citations

Rebuilding a broken heart: Lessons from developmental and regenerative biology

Martinez, N. & Bressan, M. C., Nov 1 2016, In : Development (Cambridge). 143, 21, p. 3866-3870 5 p.

Research output: Contribution to journalReview article

4 Scopus citations

Reconciling the understanding of 'hydrophobicity' with physics-based models of proteins

Harris, R. C. & Pettitt, B. M., Feb 2 2016, In : Journal of Physics Condensed Matter. 28, 8, 083003.

Research output: Contribution to journalReview article

12 Scopus citations

Regulation of transcription factors via natural decoys in genomic DNA

Kemme, C. A., Nguyen, D., Chattopadhyay, A. & Iwahara, J., Aug 7 2016, In : Transcription. 7, 4, p. 115-120 6 p.

Research output: Contribution to journalReview article

10 Scopus citations

Therapeutic potential of spirooxindoles as antiviral agents

Ye, N., Chen, H., Wold, E. A., Shi, P. Y. & Zhou, J., Jun 10 2016, In : ACS Infectious Diseases. 2, 6, p. 382-392 11 p.

Research output: Contribution to journalReview article

163 Scopus citations
2015

H-NS Regulates Gene Expression and Compacts the Nucleoid: Insights from Single-Molecule Experiments

Winardhi, R. S., Yan, J. & Kenney, L. J., Oct 6 2015, In : Biophysical journal. 109, 7, p. 1321-1329 9 p.

Research output: Contribution to journalReview article

Open Access
43 Scopus citations

Integrator: Surprisingly diverse functions in gene expression

Baillat, D. & Wagner, E. J., May 1 2015, In : Trends in biochemical sciences. 40, 5, p. 257-264 8 p.

Research output: Contribution to journalReview article

38 Scopus citations

Talin Dependent Mechanosensitivity of Cell Focal Adhesions

Yan, J., Yao, M., Goult, B. T. & Sheetz, M. P., 2015, In : Cellular and Molecular Bioengineering. 8, 1, p. 151-159 9 p.

Research output: Contribution to journalReview article

Open Access
49 Scopus citations

Targeting dengue virus NS4B protein for drug discovery

Xie, X., Zou, J., Wang, Q. Y. & Shi, P. Y., Jun 2015, In : Antiviral research. 118, p. 39-45 7 p., 3603.

Research output: Contribution to journalReview article

41 Scopus citations

Unlocking proteomic heterogeneity in complex diseases through visual analytics

Bhavnani, S. K., Dang, B., Bellala, G., Divekar, R., Visweswaran, S., Brasier, A. R. & Kurosky, A., Apr 1 2015, In : Proteomics. 15, 8, p. 1405-1418 14 p.

Research output: Contribution to journalReview article

3 Scopus citations
2014

Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer

Ware, K. E., Garcia-Blanco, M. A., Armstrong, A. J. & Dehm, S. M., Aug 2014, In : Endocrine-Related Cancer. 21, 4, p. T87-T103

Research output: Contribution to journalReview article

88 Scopus citations

Dengue Virus Cellular Receptors and Tropism

Reyes-del Valle, J., Salas-Benito, J., Soto-Acosta, R. & del Angel, R. M., Mar 1 2014, In : Current Tropical Medicine Reports. 1, 1, p. 36-43 8 p.

Research output: Contribution to journalReview article

9 Scopus citations

Dipeptidyl peptidase IV inhibitors and ischemic myocardial injury

Yoon, A. H., Ye, Y. & Birnbaum, Y., Jan 1 2014, In : Journal of Cardiovascular Pharmacology and Therapeutics. 19, 5, p. 417-425 9 p.

Research output: Contribution to journalReview article

7 Scopus citations

Integrative biological analysis for neuropsychopharmacology

Emmett, M. R., Kroes, R. A., Moskal, J. R., Conrad, C. A., Priebe, W., Laezza, F., Meyer-Baese, A. & Nilsson, C. L., Jan 2014, In : Neuropsychopharmacology. 39, 1, p. 5-23 19 p.

Research output: Contribution to journalReview article

16 Scopus citations

Isothermal titration calorimetry of membrane proteins - Progress and challenges

Rajarathnam, K. & Rösgen, J., Jan 1 2014, In : Biochimica et Biophysica Acta - Biomembranes. 1838, 1 PARTA, p. 69-77 9 p.

Research output: Contribution to journalReview article

51 Scopus citations

Targeting host factors to treat West Nile and dengue viral infections

Krishnan, M. N. & Garcia-Blanco, M. A., Feb 10 2014, In : Viruses. 6, 2, p. 683-708 26 p.

Research output: Contribution to journalReview article

43 Scopus citations
2013

Molecular epidemiology and evolution of West Nile virus in North America

Mann, B. R., McMullen, A. R., Swetnam, D. M. & Barrett, A. D. T., Oct 16 2013, In : International Journal of Environmental Research and Public Health. 10, 10, p. 5111-5129 19 p.

Research output: Contribution to journalReview article

34 Scopus citations

Non-mRNA 3′ end formation: How the other half lives

Peart, N., Sataluri, A., Baillat, D. & Wagner, E. J., Sep 1 2013, In : Wiley Interdisciplinary Reviews: RNA. 4, 5, p. 491-506 16 p.

Research output: Contribution to journalReview article

16 Scopus citations

Physico-chemical foundations underpinning microarray and next-generation sequencing experiments

Harrison, A., Binder, H., Buhot, A., Burden, C. J., Carlon, E., Gibas, C., Gamble, L. J., Halperin, A., Hooyberghs, J., Kreil, D. P., Levicky, R., Noble, P. A., Ott, A., Pettitt, B. M., Tautz, D. & Pozhitkov, A. E., Mar 2013, In : Nucleic acids research. 41, 5, p. 2779-2796 18 p.

Research output: Contribution to journalReview article

43 Scopus citations

Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich et al.

Gore, A. C., Balthazart, J., Bikle, D., Carpenter, D. O., Crews, D., Czernichow, P., Diamanti-Kandarakis, E., Dores, R. M., Grattan, D., Hof, P. R., Hollenberg, A. N., Lange, C., Lee, A. V., Levine, J. E., Millar, R. P., Nelson, R. J., Porta, M., Poth, M., Power, D. M., Prins, G. S. & 13 others, Ridgway, E. C., Rissman, E. F., Romijn, J. A., Sawchenko, P. E., Sly, P. D., Söder, O., Taylor, H. S., Tena-Sempere, M., Vaudry, H., Wallen, K., Wang, Z., Wartofsky, L. & Watson, C. S., Dec 2013, In : European Journal of Endocrinology. 169, 6, p. E1-E4

Research output: Contribution to journalReview article

4 Scopus citations