Research Output 1985 2013

  • 2075 Citations
  • 26 h-Index
  • 53 Article
  • 3 Conference contribution
  • 1 Letter
2013
4 Citations (Scopus)
Chloramphenicol Resistance
Electrospray ionization
Electrospray Ionization Mass Spectrometry
antibiotics
Liquid chromatography
2011
7 Citations (Scopus)

PharmaSat: Drug dose response in microgravity from a free-flying integrated biofluidic/optical culture-and-analysis satellite

Ricco, A. J., Parra, M., Niesel, D., Piccini, M., Ly, D., McGinnis, M., Kudlicki, A., Hines, J. W., Timucin, L., Beasley, C., Ricks, R., McIntyre, M., Friedericks, C., Henschke, M., Leung, R., Diaz-Aguado, M., Kitts, C., Mas, I., Rasay, M., Agasid, E. & 4 others, Luzzi, E., Ronzano, K., Squires, D. & Yost, B., 2011, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 7929. 79290T

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microgravity
Dose-response
microgravity
Nanosatellites
nanosatellites
2010
9 Citations (Scopus)

Pharmasat: Drug dose dependence results from an autonomous microsystem-based small satellite in low earth orbit

Ricco, A. J., Parra, M., Piccini, M., Ly, D., Niesel, D., McGinnis, M., Kudlicki, A., Hines, J. W., Timucin, L., Beasley, C., Ricks, R., McIntyre, M., Friedericks, C., Henschke, M., Leung, R., Diaz-Aguado, M., Kitts, C., Mas, I., Rasay, R., Agasid, E. & 4 others, Luzzi, E., Ronzano, K., Squires, D. & Yost, B., Jan 1 2010, 2010 Solid-State Sensors, Actuators, and Microsystems Workshop. Monk, D. J. & Turner, K. L. (eds.). Transducer Research Foundation, p. 110-113 4 p. (Technical Digest - Solid-State Sensors, Actuators, and Microsystems Workshop).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Antifungal agents
Containment vessels
Microsystems
Microorganisms
Yeast
2009
4 Citations (Scopus)

Global transcription profiling and virulence potential of Streptococcus pneumoniae after serial passage

Pandya, U., Sinha, M., Luxon, B. A., Watson, D. A. & Niesel, D., Aug 15 2009, In : Gene. 443, 1-2, p. 22-31 10 p.

Research output: Contribution to journalArticle

Serial Passage
Streptococcus pneumoniae
Virulence
Gene Expression
Genes
2008
31 Citations (Scopus)

Levofloxacin rescues mice from lethal intra-nasal infections with virulent Francisella tularensis and induces immunity and production of protective antibody

Klimpel, G. R., Eaves-Pyles, T., Moen, S. T., Taormina, J., Peterson, J., Chopra, A., Niesel, D., Carness, P., Haithcoat, J. L., Kirtley, M. & Nasr, A. B., Dec 9 2008, In : Vaccine. 26, 52, p. 6874-6882 9 p.

Research output: Contribution to journalArticle

Francisella tularensis
Levofloxacin
Nose
Antibody Formation
Immunity
30 Citations (Scopus)

The effects of low-shear stress on Adherent-invasive Escherichia coli

Allen, C. A., Niesel, D. & Torres, A., Jun 2008, In : Environmental Microbiology. 10, 6, p. 1512-1525 14 p.

Research output: Contribution to journalArticle

Mutagenesis
shear stress
Oxidative Stress
Escherichia coli
Mechanical Stress
2007
3 Citations (Scopus)

Bed rest and immunity

Sonnenfeld, G., Aviles, H., Butel, J. S., Shearer, W. T., Niesel, D., Pandya, U., Allen, C., Ochs, H. D., Blancher, A. & Abbal, M., Feb 2007, In : Acta Astronautica. 60, 4-7 SPEC. ISS., p. 234-236 3 p.

Research output: Contribution to journalArticle

Immune system
Space flight
Immunization
Bacteriophages
Viruses
12 Citations (Scopus)

Transcription profiles of Streptococcus pneumoniae grown under different conditions of normal gravitation

Allen, C. A., Galindo, C. L., Pandya, U., Watson, D. A., Chopra, A. & Niesel, D., Feb 2007, In : Acta Astronautica. 60, 4-7 SPEC. ISS., p. 433-444 12 p.

Research output: Contribution to journalArticle

Microgravity
Transcription
Gravitation
Genes
Cluster analysis
2005
7 Citations (Scopus)

Global profiling of Streptococcus pneumoniae gene expression at different growth temperatures

Pandya, U., Allen, C. A., Watson, D. A. & Niesel, D., Oct 24 2005, In : Gene. 360, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

Streptococcus pneumoniae
Gene Expression
Temperature
Growth
Genes
27 Citations (Scopus)

Murein lipoprotein is a critical outer membrane component involved in Salmonella enterica serovar typhimurium systemic infection

Fadl, A. A., Sha, J., Klimpel, G. R., Olano, J., Niesel, D. & Chopra, A., Feb 2005, In : Infection and Immunity. 73, 2, p. 1081-1096 16 p.

Research output: Contribution to journalArticle

Salmonella enterica
Peptidoglycan
Lipoproteins
Membranes
Infection
2004
59 Citations (Scopus)

The two murein lipoproteins of Salmonella enterica serovar typhimurium contribute to the virulence of the organism

Sha, J., Fadl, A. A., Klimpel, G. R., Niesel, D., Popov, V. & Chopra, A., Jul 2004, In : Infection and Immunity. 72, 7, p. 3987-4003 17 p.

Research output: Contribution to journalArticle

Salmonella enterica
Peptidoglycan
Lipoproteins
Virulence
Interleukin-8
2002

SELDI protein expression profiling & biomarker identification of Streptococcus pneumoniae

Pandya, U., Niesel, D. & Dang, T., 2002, Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. p. 243-244 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomarkers
Proteins
Sonication
Histidine
Mass spectrometry
2001
28 Citations (Scopus)

Dr operon-associated invasiveness of Escherichia coli from pregnant patients with pyelonephritis

Goluszko, P., Niesel, D., Nowicki, B., Selvarangan, R., Nowicki, S., Hart, A., Pawelczyk, E., Das, M., Urvil, P. & Hasan, R., 2001, In : Infection and Immunity. 69, 7, p. 4678-4680 3 p.

Research output: Contribution to journalArticle

Pyelonephritis
Operon
HeLa Cells
Escherichia coli
Gentamicins
15 Citations (Scopus)

Identification and characterization of an in vivo regulated D15/Oma87 homologue in Shigella flexneri using differential display polymerase chain reaction

Robb, C. W., Orihuela, C. J., Ekkelenkamp, M. B. & Niesel, D., Jan 10 2001, In : Gene. 262, 1-2, p. 169-177 9 p.

Research output: Contribution to journalArticle

Shigella flexneri
Polymerase Chain Reaction
Genes
Pasteurella multocida
Haemophilus influenzae
15 Citations (Scopus)

Streptococcus pneumoniae PstS production is phosphate responsive and enhanced during growth in the murine peritoneal cavity

Orihuela, C. J., Mills, J., Robb, C. W., Wilson, C. J., Watson, D. A. & Niesel, D., 2001, In : Infection and Immunity. 69, 12, p. 7565-7571 7 p.

Research output: Contribution to journalArticle

Peritoneal Cavity
Streptococcus pneumoniae
Phosphates
Growth
Northern Blotting

Undergraduates must learn to communicate... [3]

Watson, D. A., Davis, B. R. & Niesel, D., Jun 28 2001, In : Nature. 411, 6841, p. 992 1 p.

Research output: Contribution to journalArticle

2000
61 Citations (Scopus)

Neutrophil activation by bacterial lipoprotein versus lipopolysaccharide: Differential requirements for serum and CD14

Soler-Rodriguez, A. M., Zhang, H., Lichenstein, H. S., Qureshi, N., Niesel, D., Crowe, S. E., Peterson, J. & Kumpel, G. R., Mar 1 2000, In : Journal of Immunology. 164, 5, p. 2674-2683 10 p.

Research output: Contribution to journalArticle

Neutrophil Activation
Lipoproteins
Lipopolysaccharides
Serum
Escherichia coli
17 Citations (Scopus)

Peritoneal culture alters Streptococcus pneumoniae protein profiles and virulence properties

Orihuela, C. J., Janssen, R., Robb, C. W., Watson, D. A. & Niesel, D., 2000, In : Infection and Immunity. 68, 10, p. 6082-6086 5 p.

Research output: Contribution to journalArticle

Streptococcus pneumoniae
Virulence
Peritoneal Cavity
Virulence Factors
Serum
1999
33 Citations (Scopus)

Role of Salmonella enterotoxin in overall virulence of the organism

Chopra, A., Huang, J. H., Xu, X. J., Burden, K., Niesel, D., Rosenbaum, M. W., Popov, V. & Peterson, J., Sep 1999, In : Microbial Pathogenesis. 27, 3, p. 155-171 17 p.

Research output: Contribution to journalArticle

Virulence
Salmonella
Lethal Dose 50
Bacteria
Genes
1998
2 Citations (Scopus)

Expression of an 18 kDa::PhoA fusion protein in Mycobacterium spp

Robb, C. W., Ni, H., Wang, H., Barrett, A. & Niesel, D., Aug 1 1998, In : Journal of Microbiological Methods. 33, 3, p. 245-254 10 p.

Research output: Contribution to journalArticle

Phosphoprotein Phosphatases
Mycobacterium
Phosphoric Monoester Hydrolases
Antigens
Synthetic Vaccines
73 Citations (Scopus)

Lipoprotein release by bacteria: Potential factor in bacterial pathogenesis

Zhang, H., Niesel, D., Peterson, J. & Klimpel, G. R., 1998, In : Infection and Immunity. 66, 11, p. 5196-5201 6 p.

Research output: Contribution to journalArticle

Lipoproteins
Bacteria
Escherichia coli
Lipopolysaccharides
Macrophages
1997
94 Citations (Scopus)

Bacterial Lipoprotein and Lipopolysaccharide Act Synergistically to Induce Lethal Shock and Proinflammatory Cytokine Production

Zhang, H., Peterson, J., Niesel, D. & Klimpel, G. R., Nov 15 1997, In : Journal of Immunology. 159, 10, p. 4868-4878 11 p.

Research output: Contribution to journalArticle

Lipoproteins
Lipopolysaccharides
Shock
Cytokines
Septic Shock
23 Citations (Scopus)

Lipoprotein from Yersinia enterocolitica Contains Epitopes That Cross-React with the Human Thyrotropin Receptor

Zhang, H., Kaur, I., Niesel, D., Seetharamaiah, G. S., Peterson, J., Prabhakar, B. S. & Klimpel, G. R., Feb 15 1997, In : Journal of Immunology. 158, 4, p. 1976-1983 8 p.

Research output: Contribution to journalArticle

Thyrotropin Receptors
Yersinia enterocolitica
Lipoproteins
Epitopes
Yersinia

Summer research

Watson, D. A. & Niesel, D., Oct 27 1997, In : Scientist. 11, 21

Research output: Contribution to journalArticle

1996
43 Citations (Scopus)

A role for stem cell factor (SCF): c-kit interaction(s) in the intestinal tract response to Salmonella typhimurium infection

Klimpel, G. R., Langley, K. E., Wypych, J., Abrams, J. S., Chopra, A. & Niesel, D., Jul 1 1996, In : Journal of Experimental Medicine. 184, 1, p. 271-276 6 p.

Research output: Contribution to journalArticle

Stem Cell Factor
Salmonella Infections
Salmonella typhimurium
Salmonella
Proto-Oncogene Proteins c-kit
3 Citations (Scopus)

Treatment of HeLa cells with bacterial water extracts inhibits Shigella flexneri invasion

DiNovo, B. B., Doan, R., Dyer, R. B., Baron, S., Herzog, N. K. & Niesel, D., Sep 1996, In : FEMS Immunology and Medical Microbiology. 15, 2-3, p. 149-158 10 p.

Research output: Contribution to journalArticle

Shigella flexneri
HeLa Cells
Phosphotyrosine
Water
Proteins
21 Citations (Scopus)

Yersinia enterocolitica envelope proteins that are crossreactive with the thyrotropin receptor (TSHR) also have B-cell mitogenic activity

Zhang, H., Kaur, I., Niesel, D., Seetharamaiah, G. S., Peterson, J., Justement, L. B., Prabhakar, B. S. & Klimpel, G. R., Aug 1996, In : Journal of Autoimmunity. 9, 4, p. 509-516 8 p.

Research output: Contribution to journalArticle

Thyrotropin Receptors
Yersinia enterocolitica
B-Lymphocytes
Yersinia
Graves Disease
1995
83 Citations (Scopus)

Cholera toxin and Salmonella typhimurium induce different cytokine profiles in the gastrointestinal tract

Klimpel, G. R., Asuncion, M., Haithcoat, J. & Niesel, D., 1995, In : Infection and Immunity. 63, 3, p. 1134-1137 4 p.

Research output: Contribution to journalArticle

Cholera Toxin
Salmonella typhimurium
Gastrointestinal Tract
Cytokines
Fluids and Secretions
28 Citations (Scopus)

Human T-cell recognition of Listeria monocytogenes: Recognition of listeriolysin O by TcRαβ+ and TcRγδ+ T cells

Guo, Y., Ziegler, H. K., Safley, S. A., Niesel, D., Vaidya, S. & Klimpel, G. R., 1995, In : Infection and Immunity. 63, 6, p. 2288-2294 7 p.

Research output: Contribution to journalArticle

Listeria monocytogenes
T-Lymphocytes
Listeria
Blood Cells
Peptides
2 Citations (Scopus)

Shigella flexneri-HeLa cell interactions: A putative role for host cell protein kinases

Collaco, C., Dyer, R. B., Doan, R., Herzog, N. K. & Niesel, D., 1995, In : FEMS Immunology and Medical Microbiology. 10, 2, p. 93-100 8 p.

Research output: Contribution to journalArticle

Shigella flexneri
HeLa Cells
Cell Communication
Protein Kinases
Phosphotyrosine
1994
29 Citations (Scopus)

Purification and characterization of Yersinia enterocolitica envelope proteins which induce antibodies that react with human thyrotropin receptor

Luo, G., Seetharamaiah, G. S., Niesel, D., Zhang, H., Peterson, J., Prabhakar, B. S. & Klimpel, G. R., Mar 1 1994, In : Journal of Immunology. 152, 5, p. 2555-2561 7 p.

Research output: Contribution to journalArticle

Thyrotropin Receptors
Yersinia enterocolitica
Antibodies
Yersinia
Proteins
1993
37 Citations (Scopus)

Immunization of Mice with Yersinia enterocolitica Leads to the Induction of Antithyrotropin Receptor Antibodies

Luo, G., Fan, J. L., Seetharamaiah, G. S., Desai, R. K., Dallas, J. S., Wagle, N., Doan, R., Niesel, D., Klimpel, G. R. & Prabhakar, B. S., Jul 15 1993, In : Journal of Immunology. 151, 2, p. 922-928 7 p.

Research output: Contribution to journalArticle

Yersinia enterocolitica
Immunization
Antibodies
Autoantibodies
Shigella flexneri
28 Citations (Scopus)

Ity influences the production of IFN-γ by murine splenocytes stimulated in vitro with Salmonella typhimurium

Ramarathinam, L., Niesel, D. & Klimpel, G. R., May 1 1993, In : Journal of Immunology. 150, 9, p. 3965-3972 8 p.

Research output: Contribution to journalArticle

Salmonella typhimurium
Spleen
Salmonella Infections
Wool
Nylons
83 Citations (Scopus)

Salmonella typhimurium induces IFN-γ production in murine splenocytes: Role of natural killer cells and macrophages

Ramarathinam, L., Niesel, D. & Klimpel, G. R., May 1 1993, In : Journal of Immunology. 150, 9, p. 3973-3981 9 p.

Research output: Contribution to journalArticle

Salmonella typhimurium
Natural Killer Cells
Macrophages
Wool
Nylons
55 Citations (Scopus)

Shigella flexneri invasion of HeLa cells induces NF-κB DNA-binding activity

Dyer, R. B., Collaco, C. R., Niesel, D. & Herzog, N. K., 1993, In : Infection and Immunity. 61, 10, p. 4427-4433 7 p.

Research output: Contribution to journalArticle

Shigella flexneri
HeLa Cells
Transcription Factors
DNA
Transcription Factor RelA
40 Citations (Scopus)

Tumor Necrosis Factor (TNFα) Regulates Intestinal Mucus Production during Salmonellosis

Arnold, J. W., Klimpel, G. R. & Niesel, D., Oct 15 1993, In : Cellular Immunology. 151, 2, p. 336-344 9 p.

Research output: Contribution to journalArticle

Salmonella Infections
Mucus
Goblet Cells
Tumor Necrosis Factor-alpha
Salmonella
84 Citations (Scopus)

Tumor necrosis factor alpha binding to bacteria: Evidence for a high- affinity receptor and alteration of bacterial virulence properties

Luo, G., Niesel, D., Shaban, R. A., Grimm, E. A. & Klimpel, G. R., 1993, In : Infection and Immunity. 61, 3, p. 830-835 6 p.

Research output: Contribution to journalArticle

Virulence
Tumor Necrosis Factor-alpha
Bacteria
Gram-Negative Bacteria
Shigella flexneri
71 Citations (Scopus)

Tumor necrosis factor-α mediates the early pathology in Salmonella infection of the gastrointestinal tract

Arnold, J. W., Niesel, D., Annable, C. R., Hess, C. B., Asuncion, M., Cho, Y. J., Peterson, J. & Klimpel, G. R., Mar 1993, In : Microbial Pathogenesis. 14, 3, p. 217-227 11 p.

Research output: Contribution to journalArticle

Salmonella Infections
Gastrointestinal Tract
Tumor Necrosis Factor-alpha
Pathology
Salmonella typhimurium
1992
13 Citations (Scopus)
Listeria
Listeria monocytogenes
Major Histocompatibility Complex
Natural Killer Cells
Lymphocytes
3 Citations (Scopus)

Non-immunological detection of PhoA fusion proteins

Phillips, L. H., Chambers, L., Belmares, R. & Niesel, D., 1992, In : Journal of Microbiological Methods. 16, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

Proteins
Alkaline Phosphatase
Nitroblue Tetrazolium
Collodion
Polysorbates
1991
67 Citations (Scopus)

Interferon gamma (IFN-γ) production by gut-associated lymphoid tissue and spleen following oral Salmonella typhimurium challenge

Ramarathinam, L., Shaban, R. A., Niesel, D. & Klimpel, G. R., 1991, In : Microbial Pathogenesis. 11, 5, p. 347-356 10 p.

Research output: Contribution to journalArticle

Lymphoid Tissue
Salmonella typhimurium
Interferon-gamma
Spleen
Peyer's Patches
588 Citations (Scopus)

The Interferons: Mechanisms of Action and Clinical Applications

Baron, S., Tyring, S. K., Fleischmann, W. R., Coppenhaver, D. H., Niesel, D., Klimpel, G. R., Stanton, G. J. & Hughes, T. K., Sep 11 1991, In : JAMA: The Journal of the American Medical Association. 266, 10, p. 1375-1383 9 p.

Research output: Contribution to journalArticle

Interferons
Chronic Granulomatous Disease
Drug Approval
Hairy Cell Leukemia
Condylomata Acuminata
1990
24 Citations (Scopus)

Bacteria-infected fibroblasts have enhanced susceptibility to the cytotoxic action of tumor necrosis factor

Klimpel, G. R., Shaban, R. & Niesel, D., Jul 15 1990, In : Journal of Immunology. 145, 2, p. 711-717 7 p.

Research output: Contribution to journalArticle

Tumor Necrosis Factor-alpha
Fibroblasts
Bacteria
Shigella flexneri
Listeria monocytogenes
9 Citations (Scopus)

Interferon production by Shigella flexneri-infected fibroblasts depends upon intracellular bacterial metabolism

Hess, C. B., Niesel, D., Holmgren, J., Jonson, G. & Klimpel, G. R., 1990, In : Infection and Immunity. 58, 2, p. 399-405 7 p.

Research output: Contribution to journalArticle

Shigella flexneri
Interferons
Fibroblasts
Embryonic Structures
Bacterial RNA
1989
11 Citations (Scopus)

Recently described innate broad spectrum virus inhibitors

Baron, S., Niesel, D., Singh, I. P., McKerlie, L., Poast, J., Chopra, A., Antonelli, G., Dianzani, F. & Coppenhaver, D. H., 1989, In : Microbial Pathogenesis. 7, 4, p. 237-247 11 p.

Research output: Contribution to journalArticle

Blood Physiological Phenomena
Biological Factors
Molecular Weight
Viruses
18 Citations (Scopus)

The induction of interferon production in fibroblasts by invasive bacteria: a comparison of Salmonella and Shigella species

Hess, C. B., Niesel, D. & Klimpel, G. R., 1989, In : Microbial Pathogenesis. 7, 2, p. 111-120 10 p.

Research output: Contribution to journalArticle

Shigella
Salmonella
Interferons
Fibroblasts
Bacteria
1988
4 Citations (Scopus)
Divalent Cations
HeLa Cells
Salmonella
Cytotoxins
Calcium
19 Citations (Scopus)

Natural killer cell activation and interferon production by peripheral blood lymphocytes after exposure to bacteria

Klimpel, G. R., Niesel, D., Asuncion, M. & Klimpel, K. D., 1988, In : Infection and Immunity. 56, 6, p. 1436-1441 6 p.

Research output: Contribution to journalArticle

Natural Killer Cells
Interferons
Lymphocytes
Bacteria
Shigella flexneri
1987
32 Citations (Scopus)

Bacterial invasion of fibroblasts induces interferon production

Hess, C. B., Niesel, D., Cho, Y. J. & Klimpel, G. R., 1987, In : Journal of Immunology. 138, 11, p. 3949-3953 5 p.

Research output: Contribution to journalArticle

Interferon-beta
Interferons
Shigella flexneri
Shigella
Fibroblasts
2 Citations (Scopus)

Calcium enhances Salmonella typhimurium invasion of HeLa cells

Niesel, D. & Peterson, J., 1987, In : FEMS Microbiology Letters. 41, 3, p. 299-304 6 p.

Research output: Contribution to journalArticle

Salmonella typhimurium
HeLa Cells
Calcium
Magnesium
Cations