Research Output

2020

A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection

Mire, C. E., Chan, Y. P., Borisevich, V., Cross, R. W., Yan, L., Agans, K. N., Dang, H. V., Veesler, D., Fenton, K. A., Geisbert, T. W. & Broder, C. C., May 11 2020, In : Journal of Infectious Diseases. 221, p. S471-S479

Research output: Contribution to journalArticle

Open Access

Acute flaccid myelitis: Current status and diagnostic challenges

Fang, X. & Huda, R., Jul 2020, In : Journal of Clinical Neurology (Korea). 16, 3, p. 376-382 7 p.

Research output: Contribution to journalReview article

Open Access

A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

Muruato, A. E., Fontes-Garfias, C. R., Ren, P., Garcia-Blanco, M. A., Menachery, V. D., Xie, X. & Shi, P. Y., Dec 1 2020, In : Nature communications. 11, 1, 4059.

Research output: Contribution to journalArticle

Open Access

A Lethal Aerosol Exposure Model of Nipah Virus Strain Bangladesh in African Green Monkeys

Prasad, A. N., Agans, K. N., Sivasubramani, S. K., Geisbert, J. B., Borisevich, V., Mire, C. E., Lawrence, W. S., Fenton, K. A. & Geisbert, T. W., May 11 2020, In : Journal of Infectious Diseases. 221, p. S431-S435

Research output: Contribution to journalArticle

1 Scopus citations

Alternative vaccination routes against paratuberculosis modulate local immune response and interference with tuberculosis diagnosis in laboratory animal models

Arrazuria, R., Ladero, I., Molina, E., Fuertes, M., Juste, R., Fernández, M., Pérez, V., Garrido, J. & Elguezabal, N., Mar 2020, In : Veterinary Sciences. 7, 1, 8.

Research output: Contribution to journalArticle

Open Access

Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

Gilchuk, P., Murin, C. D., Milligan, J. C., Cross, R. W., Mire, C. E., Ilinykh, P. A., Huang, K., Kuzmina, N., Altman, P. X., Hui, S., Gunn, B. M., Bryan, A. L., Davidson, E., Doranz, B. J., Turner, H. L., Alkutkar, T., Flinko, R., Orlandi, C., Carnahan, R., Nargi, R. & 13 others, Bombardi, R. G., Vodzak, M. E., Li, S., Okoli, A., Ibeawuchi, M., Ohiaeri, B., Lewis, G. K., Alter, G., Bukreyev, A., Saphire, E. O., Geisbert, T. W., Ward, A. B. & Crowe, J. E., Feb 18 2020, In : Immunity. 52, 2, p. 388-403.e12

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

An Infectious cDNA Clone of SARS-CoV-2

Xie, X., Muruato, A., Lokugamage, K. G., Narayanan, K., Zhang, X., Zou, J., Liu, J., Schindewolf, C., Bopp, N. E., Aguilar, P. V., Plante, K. S., Weaver, S. C., Makino, S., LeDuc, J. W., Menachery, V. D. & Shi, P. Y., May 13 2020, In : Cell Host and Microbe. 27, 5, p. 841-848.e3

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

An Intranasal Exposure Model of Lethal Nipah Virus Infection in African Green Monkeys

Geisbert, J. B., Borisevich, V., Prasad, A. N., Agans, K. N., Foster, S. L., Deer, D. J., Cross, R. W., Mire, C. E., Geisbert, T. W. & Fenton, K. A., May 11 2020, In : Journal of Infectious Diseases. 221, p. S414-S418

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Annexin a2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and ebola virus infections

Su, Z., Chang, Q., Drelich, A., Shelite, T., Judy, B., Liu, Y., Xiao, J., Zhou, C., He, X., Jin, Y., Saito, T., Tang, S., Soong, L., Wakamiya, M., Fang, X., Bukreyev, A., Ksiazek, T., Russell, W. K. & Gong, B., Jul 2020, In : PLoS neglected tropical diseases. 14, 7, p. 1-30 30 p., e0007960.

Research output: Contribution to journalArticle

Open Access

A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2

Tai, W., Zhang, X., Drelich, A., Shi, J., Hsu, J. C., Luchsinger, L., Hillyer, C. D., Tseng, C. T. K., Jiang, S. & Du, L., 2020, (Accepted/In press) In : Cell Research.

Research output: Contribution to journalLetter

Open Access

Arrangement of the Polymerase Complexes inside a Nine-Segmented dsRNA Virus

Kaelber, J. T., Jiang, W., Weaver, S. C., Auguste, A. & Chiu, W., Jun 2 2020, In : Structure. 28, 6, p. 604-612.e3

Research output: Contribution to journalArticle

1 Scopus citations

Author Correction: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence (Nature Medicine, (2015), 21, 12, (1508-1513), 10.1038/nm.3985)

Menachery, V. D., Yount, B. L., Debbink, K., Agnihothram, S., Gralinski, L. E., Plante, J. A., Graham, R. L., Scobey, T., Ge, X. Y., Donaldson, E. F., Randell, S. H., Lanzavecchia, A., Marasco, W. A., Shi, Z. L. & Baric, R. S., Jul 1 2020, In : Nature Medicine. 26, 7, p. 1146 1 p.

Research output: Contribution to journalComment/debate

Open Access

Barrita Virus, a Novel Virus of the Patois Serogroup (Genus Orthobunyavirus; Family Peribunyaviridae)

Fernández, D., Marciel de Souza, W., Silvas, J. A., Deardorff, E. R., Widen, S., Estrada-Franco, J. G., Weaver, S. C., Nunes, M. & Aguilar, P. V., Jul 1 2020, In : The American journal of tropical medicine and hygiene. 103, 1, p. 190-192 3 p.

Research output: Contribution to journalArticle

Catching and killing of airborne SARS-CoV-2 to control spread of COVID-19 by a heated air disinfection system

Yu, L., Peel, G. K., Cheema, F. H., Lawrence, W. S., Bukreyeva, N., Jinks, C. W., Peel, J. E., Peterson, J. W., Paessler, S., Hourani, M. & Ren, Z., Dec 2020, In : Materials Today Physics. 15, 100249.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Changes in the transmission dynamic of chikungunya virus in southeastern Senegal

Sow, A., Nikolay, B., Faye, O., Cauchemez, S., Cano, J., Diallo, M., Faye, O., Sadio, B., Ndiaye, O., Weaver, S. C., Dia, A. T., Sall, A. A. & Malvy, D., 2020, In : Viruses. 12, 2, 196.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Chikungunya case classification after the experience with dengue classification: How much time will we lose?

De Góes Cavalcanti, L. P., Gadelha Farias, L. A. B., De Almeida Barreto, F. K., Siqueira, A. M. H., Ribeiro, G. S., Freitas, A. R. R., Weaver, S. C., Kitron, U. & Brito, C. A. A., Jan 1 2020, In : American Journal of Tropical Medicine and Hygiene. 102, 2, p. 257-259 3 p.

Research output: Contribution to journalReview article

Chikungunya outbreaks in India: A prospective study comparing neutralization and sequelae during two outbreaks in 2010 and 2016

Jain, J., Kaur, N., Haller, S. L., Kumar, A., Rossi, S. L., Narayanan, V., Kumar, D., Gaind, R., Weaver, S. C., Auguste, A. J. & Sunil, S., 2020, In : American Journal of Tropical Medicine and Hygiene. 102, 4, p. 857-868 12 p.

Research output: Contribution to journalReview article

1 Scopus citations

Chikungunya virus: Role of vectors in emergence from enzootic cycles

Weaver, S. C., Chen, R. & Diallo, M., 2020, In : Annual Review of Entomology. 65, p. 313-332 20 p.

Research output: Contribution to journalReview article

1 Scopus citations

Combating the great mimicker: latest progress in the development of Burkholderia pseudomallei vaccines

Khakhum, N., Chapartegui-González, I. & Torres, A. G., 2020, In : Expert review of vaccines. p. 1-8 8 p.

Research output: Contribution to journalReview article

Comparative genomics of a subset of Adherent/Invasive Escherichia coli strains isolated from individuals without inflammatory bowel disease

Barrios-Villa, E., Martínez de la Peña, C. F., Lozano-Zaraín, P., Cevallos, M. A., Torres, C., Torres, A. G. & Rocha-Gracia, R. D. C., Mar 2020, In : Genomics. 112, 2, p. 1813-1820 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Noll, K. E., Whitmore, A. C., West, A., McCarthy, M. K., Morrison, C. R., Plante, K. S., Hampton, B. K., Kollmus, H., Pilzner, C., Leist, S. R., Gralinski, L. E., Menachery, V. D., Schäfer, A., Miller, D., Shaw, G., Mooney, M., McWeeney, S., Pardo-Manuel de Villena, F., Schughart, K., Morrison, T. E. & 3 others, Baric, R. S., Ferris, M. T. & Heise, M. T., Apr 28 2020, In : Cell Reports. 31, 4, 107587.

Research output: Contribution to journalArticle

Open Access

Dianke virus: A new mesonivirus species isolated from mosquitoes in Eastern Senegal

Diagne, M. M., Gaye, A., Ndione, M. H. D., Faye, M., Fall, G., Dieng, I., Widen, S. G., Wood, T. G., Popov, V., Guzman, H., Bâ, Y., Weaver, S. C., Diallo, M., Tesh, R., Faye, O., Vasilakis, N. & Sall, A. A., Jan 2 2020, In : Virus Research. 275, 197802.

Research output: Contribution to journalArticle

1 Scopus citations

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

Maciejewski, S., Ruckwardt, T. J., Morabito, K. M., Foreman, B. M., Burgomaster, K. E., Gordon, D. N., Pelc, R. S., DeMaso, C. R., Ko, S. Y., Fisher, B. E., Yang, E. S., Nair, D., Foulds, K. E., Todd, J. P., Kong, W. P., Roy, V., Aleshnick, M., Speer, S. D., Bourne, N., Barrett, A. D. & 10 others, Nason, M. C., Roederer, M., Gaudinski, M. R., Chen, G. L., Dowd, K. A., Ledgerwood, J. E., Alter, G., Mascola, J. R., Graham, B. S. & Pierson, T. C., Jun 10 2020, In : Science Translational Medicine. 12, 547, eaaw9066.

Research output: Contribution to journalArticle

Early transcriptional changes within liver, adrenal gland, and lymphoid tissues significantly contribute to Ebola virus pathogenesis in cynomolgus macaques

Jankeel, A., Menicucci, A. R., Woolsey, C., Fenton, K., Mendoza, N., Versteeg, K., Cross, R. W., Geisbert, T. W. & Messaoudi, I., Jun 1 2020, In : Journal of virology. 94, 11, e00250-20.

Research output: Contribution to journalArticle

Ebola

Campion, E. W., Feldmann, H., Sprecher, A. & Geisbert, T. W., May 7 2020, In : New England Journal of Medicine. 382, 19, p. 1832-1842 11 p.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations
2 Scopus citations

Enteroendocrine Cells: Sensing Gut Microbiota and Regulating Inflammatory Bowel Diseases

Yu, Y., Yang, W., Li, Y. & Cong, Y., Jan 1 2020, In : Inflammatory bowel diseases. 26, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Envelope protein ubiquitination drives entry and pathogenesis of Zika virus

Giraldo, M. I., Xia, H., Aguilera-Aguirre, L., Hage, A., van Tol, S., Shan, C., Xie, X., Sturdevant, G. L., Robertson, S. J., McNally, K. L., Meade-White, K., Azar, S. R., Rossi, S. L., Maury, W., Woodson, M., Ramage, H., Johnson, J. R., Krogan, N. J., Morais, M. C., Best, S. M. & 2 others, Shi, P. Y. & Rajsbaum, R., 2020, (Accepted/In press) In : Nature.

Research output: Contribution to journalArticle

1 Scopus citations

Epigenetic suppression of HIV in myeloid cells by the BRD4-selective small molecule modulator ZL0580

Alamer, E., Zhong, C., Liu, Z., Niu, Q., Long, F., Guo, L., Gelman, B. B., Soong, L., Zhou, J. & Hu, H., Jun 1 2020, In : Journal of virology. 94, 11, e01880-19.

Research output: Contribution to journalArticle

1 Scopus citations

Erratum: Correction for Satterfield et al., "Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets" (Journal of virology (2016) 90 14 (6326-6343) PII: e00059-20)

Satterfield, B. A., Cross, R. W., Fenton, K. A., Borisevich, V., Agans, K. N., Deer, D. J., Graber, J., Basler, C. F., Geisbert, T. W. & Mire, C. E., Mar 31 2020, In : Journal of virology. 94, 8

Research output: Contribution to journalComment/debate

Open Access

Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses

Kikuti, M., Tauro, L. B., Moreira, P. S. S., Nascimento, L. C. J., Portilho, M. M., Soares, G. C., Weaver, S. C., Reis, M. G., Kitron, U. & Ribeiro, G. S., Feb 2020, In : International Journal of Infectious Diseases. 91, p. 38-43 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Exercise, redox system and neurodegenerative diseases

Quan, H., Koltai, E., Suzuki, K., Aguiar, A. S., Pinho, R., Boldogh, I., Berkes, I. & Radak, Z., Oct 1 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 10, 165778.

Research output: Contribution to journalReview article

Open Access

Finding Their Type: Elusive Antigenic Sites on Dengue Virus 3 Mapped with Human Antibodies

Sarathy, V. V. & Barrett, A. D. T., May 13 2020, In : Cell Host and Microbe. 27, 5, p. 681-682 2 p.

Research output: Contribution to journalArticle

Flavivirus Immunity in Disease Control and Viral Pathogenesis

Wang, T., Jan 1 2020, In : Viral Immunology. 33, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 5: Entomological aspects

GloPID-R Chikungunya, O'nyong-nyong and Mayaro virus Working Group, Feb 2020, In : Antiviral research. 174, 104670.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations

Hacking the host: exploitation of macrophage polarization by intracellular bacterial pathogens

Thiriot, J. D., Martinez-Martinez, Y. B., Endsley, J. J. & Torres, A. G., Feb 1 2020, In : Pathogens and disease. 78, 1

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis—A Pivotal Anti-hantaviral Role of TRAIL

Chen, Q. Z., Wang, X., Luo, F., Li, N., Zhu, N., Lu, S., Zan, Y. X., Zhong, C. J., Wang, M. R., Hu, H. T., Zhang, Y. Z., Xiong, H. R. & Hou, W., Jun 19 2020, In : Frontiers in immunology. 11, 1072.

Research output: Contribution to journalArticle

Open Access

Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway

Lu, Y., Li, C. F., Ping, N. N., Sun, Y. Y., Wang, Z., Zhao, G. X., Yuan, S. H., Zibrila, A. I., Soong, L. & Liu, J. J., May 1 2020, In : Journal of Biochemical and Molecular Toxicology. 34, 5, e22467.

Research output: Contribution to journalArticle

1 Scopus citations

Immune correlates of postexposure vaccine protection against Marburg virus

Woolsey, C., Jankeel, A., Matassov, D., Geisbert, J. B., Agans, K. N., Borisevich, V., Cross, R. W., Deer, D. J., Fenton, K. A., Latham, T. E., Gerardi, C. S., Mire, C. E., Eldridge, J. H., Messaoudi, I. & Geisbert, T. W., Dec 1 2020, In : Scientific reports. 10, 1, 3071.

Research output: Contribution to journalArticle

Open Access

Immune Predictors of Mortality after Ribonucleic Acid Virus Infection

Graham, J. B., Swarts, J. L., Menachery, V. D., Gralinski, L. E., Schäfer, A., Plante, K. S., Morrison, C. R., Voss, K. M., Green, R., Choonoo, G., Jeng, S., Miller, D. R., Mooney, M. A., McWeeney, S. K., Ferris, M. T., De Villena, F. P. M., Gale, M., Heise, M. T., Baric, R. S. & Lund, J. M., Mar 15 2020, In : Journal of Infectious Diseases. 221, 6, p. 882-889 8 p.

Research output: Contribution to journalArticle

Incrimination of mosquito vectors

Weaver, S. C., Feb 1 2020, In : Nature Microbiology. 5, 2, p. 232-233 2 p.

Research output: Contribution to journalComment/debate

In-depth characterization of a novel live-attenuated Mayaro virus vaccine candidate using an immunocompetent mouse model of Mayaro disease

Mota, M. T. D. O., Costa, V. V., Sugimoto, M. A., Guimarães, G. D. F., Queiroz-Junior, C. M., Moreira, T. P., de Sousa, C. D., Santos, F. M., Queiroz, V. F., Passos, I., Hubner, J., Souza, D. G., Weaver, S. C., Teixeira, M. M. & Nogueira, M. L., Dec 1 2020, In : Scientific reports. 10, 1, 5306.

Research output: Contribution to journalArticle

Open Access

Influence of herd immunity in the cyclical nature of arboviruses

Ribeiro, G. S., Hamer, G. L., Diallo, M., Kitron, U., Ko, A. I. & Weaver, S. C., Feb 2020, In : Current Opinion in Virology. 40, p. 1-10 10 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase

Cross, R. W., Agans, K. N., Prasad, A. N., Borisevich, V., Woolsey, C., Deer, D. J., Dobias, N. S., Geisbert, J. B., Fenton, K. A. & Geisbert, T. W., Aug 18 2020, In : Virology journal. 17, 1, 125.

Research output: Contribution to journalArticle

Open Access

Long-acting rilpivirine (RPV) preexposure prophylaxis does not inhibit vaginal transmission of RPV-resistant HIV-1 or select for high-frequency drug resistance in humanized mice

Melody, K., Roy, C. N., Kline, C., Cottrell, M. L., Evans, D., Shutt, K., Pennings, P. S., Keele, B. F., Bility, M., Kashuba, A. D. M. & Ambrose, Z., Mar 1 2020, In : Journal of virology. 94, 8, e01912-19.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Methadone Inhibits Viral Restriction Factors and Facilitates HIV Infection in Macrophages

Wang, M. R., Wu, D. D., Luo, F., Zhong, C. J., Wang, X., Zhu, N., Wu, Y. J., Hu, H. T., Feng, Y., Wang, X., Xiong, H. R. & Hou, W., Jul 3 2020, In : Frontiers in immunology. 11, 1253.

Research output: Contribution to journalArticle

Open Access

Molecular characterization of feline paramyxovirus in Japanese cat populations

Sakaguchi, S., Nakagawa, S., Mitsuhashi, S., Ogawa, M., Sugiyama, K., Tamukai, K., Koide, R., Katayama, Y., Nakano, T., Makino, S., Imanishi, T., Miyazawa, T. & Mizutani, T., Feb 1 2020, In : Archives of virology. 165, 2, p. 413-418 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Molecular Characterization of Hamster-Adapted Yellow Fever Virus

Mcarthur, M. A., Zhang, S. L., Li, L., Tesh, R. B. & Barrett, A. D. T., Mar 2020, In : Vector-Borne and Zoonotic Diseases. 20, 3, p. 222-227 6 p.

Research output: Contribution to journalArticle

Moving beyond the mousetrap: Current and emerging humanized mouse and rat models for investigating prevention and cure strategies against HIV infection and associated pathologies

Agarwal, Y., Beatty, C., Biradar, S., Castronova, I., Ho, S., Melody, K. & Bility, M. T., Apr 10 2020, In : Retrovirology. 17, 1, 8.

Research output: Contribution to journalReview article

Open Access

Mucoadhesive-to-penetrating controllable peptosomes-in-microspheres co-loaded with anti-miR-31 oligonucleotide and Curcumin for targeted colorectal cancer therapy

Zhao, R., Sujuan, D. U., Liu, Y., Cong, L. V., Song, Y., Chen, X., Zhang, B., Li, D., Gao, S., Wei, C. U. I., Plikus, M. V., Hou, X., Wu, K., Liu, Z., Liu, Z., Cong, Y., Li, Y. & Yu, Z., 2020, In : Theranostics. 10, 8, p. 3594-3611 18 p.

Research output: Contribution to journalArticle

Open Access