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2020

A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection

Mire, C. E., Chan, Y. P., Borisevich, V., Cross, R. W., Yan, L., Agans, K. N., Dang, H. V., Veesler, D., Fenton, K. A., Geisbert, T. W. & Broder, C. C., May 11 2020, In : Journal of Infectious Diseases. 221, p. S471-S479

Research output: Contribution to journalArticle

Open Access

A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

Muruato, A. E., Fontes-Garfias, C. R., Ren, P., Garcia-Blanco, M. A., Menachery, V. D., Xie, X. & Shi, P. Y., Dec 1 2020, In : Nature communications. 11, 1, 4059.

Research output: Contribution to journalArticle

Open Access

A Lethal Aerosol Exposure Model of Nipah Virus Strain Bangladesh in African Green Monkeys

Prasad, A. N., Agans, K. N., Sivasubramani, S. K., Geisbert, J. B., Borisevich, V., Mire, C. E., Lawrence, W. S., Fenton, K. A. & Geisbert, T. W., May 11 2020, In : Journal of Infectious Diseases. 221, p. S431-S435

Research output: Contribution to journalArticle

1 Scopus citations

Alternative vaccination routes against paratuberculosis modulate local immune response and interference with tuberculosis diagnosis in laboratory animal models

Arrazuria, R., Ladero, I., Molina, E., Fuertes, M., Juste, R., Fernández, M., Pérez, V., Garrido, J. & Elguezabal, N., Mar 2020, In : Veterinary Sciences. 7, 1, 8.

Research output: Contribution to journalArticle

Open Access

Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization

Gilchuk, P., Murin, C. D., Milligan, J. C., Cross, R. W., Mire, C. E., Ilinykh, P. A., Huang, K., Kuzmina, N., Altman, P. X., Hui, S., Gunn, B. M., Bryan, A. L., Davidson, E., Doranz, B. J., Turner, H. L., Alkutkar, T., Flinko, R., Orlandi, C., Carnahan, R., Nargi, R. & 13 others, Bombardi, R. G., Vodzak, M. E., Li, S., Okoli, A., Ibeawuchi, M., Ohiaeri, B., Lewis, G. K., Alter, G., Bukreyev, A., Saphire, E. O., Geisbert, T. W., Ward, A. B. & Crowe, J. E., Feb 18 2020, In : Immunity. 52, 2, p. 388-403.e12

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

An Infectious cDNA Clone of SARS-CoV-2

Xie, X., Muruato, A., Lokugamage, K. G., Narayanan, K., Zhang, X., Zou, J., Liu, J., Schindewolf, C., Bopp, N. E., Aguilar, P. V., Plante, K. S., Weaver, S. C., Makino, S., LeDuc, J. W., Menachery, V. D. & Shi, P. Y., May 13 2020, In : Cell Host and Microbe. 27, 5, p. 841-848.e3

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

An Intranasal Exposure Model of Lethal Nipah Virus Infection in African Green Monkeys

Geisbert, J. B., Borisevich, V., Prasad, A. N., Agans, K. N., Foster, S. L., Deer, D. J., Cross, R. W., Mire, C. E., Geisbert, T. W. & Fenton, K. A., May 11 2020, In : Journal of Infectious Diseases. 221, p. S414-S418

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Annexin a2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and ebola virus infections

Su, Z., Chang, Q., Drelich, A., Shelite, T., Judy, B., Liu, Y., Xiao, J., Zhou, C., He, X., Jin, Y., Saito, T., Tang, S., Soong, L., Wakamiya, M., Fang, X., Bukreyev, A., Ksiazek, T., Russell, W. K. & Gong, B., Jul 2020, In : PLoS neglected tropical diseases. 14, 7, p. 1-30 30 p., e0007960.

Research output: Contribution to journalArticle

Open Access

Arrangement of the Polymerase Complexes inside a Nine-Segmented dsRNA Virus

Kaelber, J. T., Jiang, W., Weaver, S. C., Auguste, A. & Chiu, W., Jun 2 2020, In : Structure. 28, 6, p. 604-612.e3

Research output: Contribution to journalArticle

1 Scopus citations

Barrita Virus, a Novel Virus of the Patois Serogroup (Genus Orthobunyavirus; Family Peribunyaviridae)

Fernández, D., Marciel de Souza, W., Silvas, J. A., Deardorff, E. R., Widen, S., Estrada-Franco, J. G., Weaver, S. C., Nunes, M. & Aguilar, P. V., Jul 1 2020, In : The American journal of tropical medicine and hygiene. 103, 1, p. 190-192 3 p.

Research output: Contribution to journalArticle

Catching and killing of airborne SARS-CoV-2 to control spread of COVID-19 by a heated air disinfection system

Yu, L., Peel, G. K., Cheema, F. H., Lawrence, W. S., Bukreyeva, N., Jinks, C. W., Peel, J. E., Peterson, J. W., Paessler, S., Hourani, M. & Ren, Z., Dec 2020, In : Materials Today Physics. 15, 100249.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Changes in the transmission dynamic of chikungunya virus in southeastern Senegal

Sow, A., Nikolay, B., Faye, O., Cauchemez, S., Cano, J., Diallo, M., Faye, O., Sadio, B., Ndiaye, O., Weaver, S. C., Dia, A. T., Sall, A. A. & Malvy, D., 2020, In : Viruses. 12, 2, 196.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Comparative genomics of a subset of Adherent/Invasive Escherichia coli strains isolated from individuals without inflammatory bowel disease

Barrios-Villa, E., Martínez de la Peña, C. F., Lozano-Zaraín, P., Cevallos, M. A., Torres, C., Torres, A. G. & Rocha-Gracia, R. D. C., Mar 2020, In : Genomics. 112, 2, p. 1813-1820 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Noll, K. E., Whitmore, A. C., West, A., McCarthy, M. K., Morrison, C. R., Plante, K. S., Hampton, B. K., Kollmus, H., Pilzner, C., Leist, S. R., Gralinski, L. E., Menachery, V. D., Schäfer, A., Miller, D., Shaw, G., Mooney, M., McWeeney, S., Pardo-Manuel de Villena, F., Schughart, K., Morrison, T. E. & 3 others, Baric, R. S., Ferris, M. T. & Heise, M. T., Apr 28 2020, In : Cell Reports. 31, 4, 107587.

Research output: Contribution to journalArticle

Open Access

Dianke virus: A new mesonivirus species isolated from mosquitoes in Eastern Senegal

Diagne, M. M., Gaye, A., Ndione, M. H. D., Faye, M., Fall, G., Dieng, I., Widen, S. G., Wood, T. G., Popov, V., Guzman, H., Bâ, Y., Weaver, S. C., Diallo, M., Tesh, R., Faye, O., Vasilakis, N. & Sall, A. A., Jan 2 2020, In : Virus Research. 275, 197802.

Research output: Contribution to journalArticle

1 Scopus citations

Distinct neutralizing antibody correlates of protection among related Zika virus vaccines identify a role for antibody quality

Maciejewski, S., Ruckwardt, T. J., Morabito, K. M., Foreman, B. M., Burgomaster, K. E., Gordon, D. N., Pelc, R. S., DeMaso, C. R., Ko, S. Y., Fisher, B. E., Yang, E. S., Nair, D., Foulds, K. E., Todd, J. P., Kong, W. P., Roy, V., Aleshnick, M., Speer, S. D., Bourne, N., Barrett, A. D. & 10 others, Nason, M. C., Roederer, M., Gaudinski, M. R., Chen, G. L., Dowd, K. A., Ledgerwood, J. E., Alter, G., Mascola, J. R., Graham, B. S. & Pierson, T. C., Jun 10 2020, In : Science Translational Medicine. 12, 547, eaaw9066.

Research output: Contribution to journalArticle

Early transcriptional changes within liver, adrenal gland, and lymphoid tissues significantly contribute to Ebola virus pathogenesis in cynomolgus macaques

Jankeel, A., Menicucci, A. R., Woolsey, C., Fenton, K., Mendoza, N., Versteeg, K., Cross, R. W., Geisbert, T. W. & Messaoudi, I., Jun 1 2020, In : Journal of virology. 94, 11, e00250-20.

Research output: Contribution to journalArticle

2 Scopus citations

Enteroendocrine Cells: Sensing Gut Microbiota and Regulating Inflammatory Bowel Diseases

Yu, Y., Yang, W., Li, Y. & Cong, Y., Jan 1 2020, In : Inflammatory bowel diseases. 26, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Envelope protein ubiquitination drives entry and pathogenesis of Zika virus

Giraldo, M. I., Xia, H., Aguilera-Aguirre, L., Hage, A., van Tol, S., Shan, C., Xie, X., Sturdevant, G. L., Robertson, S. J., McNally, K. L., Meade-White, K., Azar, S. R., Rossi, S. L., Maury, W., Woodson, M., Ramage, H., Johnson, J. R., Krogan, N. J., Morais, M. C., Best, S. M. & 2 others, Shi, P. Y. & Rajsbaum, R., 2020, (Accepted/In press) In : Nature.

Research output: Contribution to journalArticle

1 Scopus citations

Epigenetic suppression of HIV in myeloid cells by the BRD4-selective small molecule modulator ZL0580

Alamer, E., Zhong, C., Liu, Z., Niu, Q., Long, F., Guo, L., Gelman, B. B., Soong, L., Zhou, J. & Hu, H., Jun 1 2020, In : Journal of virology. 94, 11, e01880-19.

Research output: Contribution to journalArticle

1 Scopus citations

Evaluation of two commercially available chikungunya virus IgM enzyme-linked immunoassays (ELISA) in a setting of concomitant transmission of chikungunya, dengue and Zika viruses

Kikuti, M., Tauro, L. B., Moreira, P. S. S., Nascimento, L. C. J., Portilho, M. M., Soares, G. C., Weaver, S. C., Reis, M. G., Kitron, U. & Ribeiro, G. S., Feb 2020, In : International Journal of Infectious Diseases. 91, p. 38-43 6 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Finding Their Type: Elusive Antigenic Sites on Dengue Virus 3 Mapped with Human Antibodies

Sarathy, V. V. & Barrett, A. D. T., May 13 2020, In : Cell Host and Microbe. 27, 5, p. 681-682 2 p.

Research output: Contribution to journalArticle

Hacking the host: exploitation of macrophage polarization by intracellular bacterial pathogens

Thiriot, J. D., Martinez-Martinez, Y. B., Endsley, J. J. & Torres, A. G., Feb 1 2020, In : Pathogens and disease. 78, 1

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis—A Pivotal Anti-hantaviral Role of TRAIL

Chen, Q. Z., Wang, X., Luo, F., Li, N., Zhu, N., Lu, S., Zan, Y. X., Zhong, C. J., Wang, M. R., Hu, H. T., Zhang, Y. Z., Xiong, H. R. & Hou, W., Jun 19 2020, In : Frontiers in immunology. 11, 1072.

Research output: Contribution to journalArticle

Open Access

Hydrogen-rich water alleviates cyclosporine A-induced nephrotoxicity via the Keap1/Nrf2 signaling pathway

Lu, Y., Li, C. F., Ping, N. N., Sun, Y. Y., Wang, Z., Zhao, G. X., Yuan, S. H., Zibrila, A. I., Soong, L. & Liu, J. J., May 1 2020, In : Journal of Biochemical and Molecular Toxicology. 34, 5, e22467.

Research output: Contribution to journalArticle

1 Scopus citations

Immune correlates of postexposure vaccine protection against Marburg virus

Woolsey, C., Jankeel, A., Matassov, D., Geisbert, J. B., Agans, K. N., Borisevich, V., Cross, R. W., Deer, D. J., Fenton, K. A., Latham, T. E., Gerardi, C. S., Mire, C. E., Eldridge, J. H., Messaoudi, I. & Geisbert, T. W., Dec 1 2020, In : Scientific reports. 10, 1, 3071.

Research output: Contribution to journalArticle

Open Access

Immune Predictors of Mortality after Ribonucleic Acid Virus Infection

Graham, J. B., Swarts, J. L., Menachery, V. D., Gralinski, L. E., Schäfer, A., Plante, K. S., Morrison, C. R., Voss, K. M., Green, R., Choonoo, G., Jeng, S., Miller, D. R., Mooney, M. A., McWeeney, S. K., Ferris, M. T., De Villena, F. P. M., Gale, M., Heise, M. T., Baric, R. S. & Lund, J. M., Mar 15 2020, In : Journal of Infectious Diseases. 221, 6, p. 882-889 8 p.

Research output: Contribution to journalArticle

In-depth characterization of a novel live-attenuated Mayaro virus vaccine candidate using an immunocompetent mouse model of Mayaro disease

Mota, M. T. D. O., Costa, V. V., Sugimoto, M. A., Guimarães, G. D. F., Queiroz-Junior, C. M., Moreira, T. P., de Sousa, C. D., Santos, F. M., Queiroz, V. F., Passos, I., Hubner, J., Souza, D. G., Weaver, S. C., Teixeira, M. M. & Nogueira, M. L., Dec 1 2020, In : Scientific reports. 10, 1, 5306.

Research output: Contribution to journalArticle

Open Access

Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase

Cross, R. W., Agans, K. N., Prasad, A. N., Borisevich, V., Woolsey, C., Deer, D. J., Dobias, N. S., Geisbert, J. B., Fenton, K. A. & Geisbert, T. W., Aug 18 2020, In : Virology journal. 17, 1, 125.

Research output: Contribution to journalArticle

Open Access

Long-acting rilpivirine (RPV) preexposure prophylaxis does not inhibit vaginal transmission of RPV-resistant HIV-1 or select for high-frequency drug resistance in humanized mice

Melody, K., Roy, C. N., Kline, C., Cottrell, M. L., Evans, D., Shutt, K., Pennings, P. S., Keele, B. F., Bility, M., Kashuba, A. D. M. & Ambrose, Z., Mar 1 2020, In : Journal of virology. 94, 8, e01912-19.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Methadone Inhibits Viral Restriction Factors and Facilitates HIV Infection in Macrophages

Wang, M. R., Wu, D. D., Luo, F., Zhong, C. J., Wang, X., Zhu, N., Wu, Y. J., Hu, H. T., Feng, Y., Wang, X., Xiong, H. R. & Hou, W., Jul 3 2020, In : Frontiers in immunology. 11, 1253.

Research output: Contribution to journalArticle

Open Access

Molecular characterization of feline paramyxovirus in Japanese cat populations

Sakaguchi, S., Nakagawa, S., Mitsuhashi, S., Ogawa, M., Sugiyama, K., Tamukai, K., Koide, R., Katayama, Y., Nakano, T., Makino, S., Imanishi, T., Miyazawa, T. & Mizutani, T., Feb 1 2020, In : Archives of virology. 165, 2, p. 413-418 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Molecular Characterization of Hamster-Adapted Yellow Fever Virus

Mcarthur, M. A., Zhang, S. L., Li, L., Tesh, R. B. & Barrett, A. D. T., Mar 2020, In : Vector-Borne and Zoonotic Diseases. 20, 3, p. 222-227 6 p.

Research output: Contribution to journalArticle

Mucoadhesive-to-penetrating controllable peptosomes-in-microspheres co-loaded with anti-miR-31 oligonucleotide and Curcumin for targeted colorectal cancer therapy

Zhao, R., Sujuan, D. U., Liu, Y., Cong, L. V., Song, Y., Chen, X., Zhang, B., Li, D., Gao, S., Wei, C. U. I., Plikus, M. V., Hou, X., Wu, K., Liu, Z., Liu, Z., Cong, Y., Li, Y. & Yu, Z., 2020, In : Theranostics. 10, 8, p. 3594-3611 18 p.

Research output: Contribution to journalArticle

Open Access

MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6

Xie, L., Chen, L., Zhong, C., Yu, T., Ju, Z., Wang, M., Xiong, H., Zeng, Y., Wang, J., Hu, H., Hou, W. & Feng, Y., Jun 29 2020, In : Retrovirology. 17, 1, 16.

Research output: Contribution to journalArticle

Open Access

New host-directed therapeutics for the treatment of Clostridioides difficile infection

Andersson, J. A., Peniche, A. G., Galindo, C. L., Boonma, P., Sha, J., Luna, R. A., Savidge, T. C., Chopra, A. K. & Dann, S. M., Mar 1 2020, In : mBio. 11, 2, e00053-20.

Research output: Contribution to journalArticle

Open Access

Novel ionophores active against La Crosse virus identified through rapid antiviral screening

Sandler, Z. J., Firpo, M. R., Omoba, O. S., Vu, M. N., Menachery, V. D. & Mounce, B. C., Jun 2020, In : Antimicrobial agents and chemotherapy. 64, 6, e00086-20.

Research output: Contribution to journalArticle

Oxytetracycline reduces inflammation and treponeme burden whereas vitamin D3 promotes β-defensin expression in bovine infectious digital dermatitis

Watts, K. M., Lahiri, P., Arrazuria, R., De Buck, J., Knight, C. G., Orsel, K., Barkema, H. W. & Cobo, E. R., Feb 1 2020, In : Cell and Tissue Research. 379, 2, p. 337-348 12 p.

Research output: Contribution to journalArticle

Palmitoylation of Hepatitis C virus NS2 regulates its subcellular localization and NS2-NS3 autocleavage

Wu, M. J., Shanmugam, S., Welsch, C. & Yi, M. K., Jan 1 2020, In : Journal of virology. 94, 1, e00906-19.

Research output: Contribution to journalArticle

Open Access

Peli1 signaling blockade attenuates congenital zika syndrome

Luo, H., Li, G., Wang, B., Tian, B., Gao, J., Zou, J., Shi, S., Zhu, S., Peng, B. H., Adam, A., Martinez, A., Hein, K., Winkelmann, E. R., Mahmoud, Y., Zhou, X., Shan, C., Rossi, S., Weaver, S., Barrett, A. D. T., Sun, S. C. & 4 others, Zhang, W., Shi, P. Y., Wu, P. & Wang, T., Jun 2020, In : PLoS pathogens. 16, 6, e1008538.

Research output: Contribution to journalArticle

Open Access

Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle

Dharmalingam, P., Talakatta, G., Mitra, J., Wang, H., Derry, P. J., Nilewski, L. G., McHugh, E. A., Fabian, R. H., Mendoza, K., Vasquez, V., Hegde, P. M., Kakadiaris, E., Roy, T., Boldogh, I., Hegde, V. L., Mitra, S., Tour, J. M., Kent, T. A. & Hegde, M. L., Mar 24 2020, In : ACS Nano. 14, 3, p. 2827-2846 20 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access

Polarized lung inflammation and Tie2/angiopoietin-mediated endothelial dysfunction during severe Orientia tsutsugamushi infection

Trent, B., Liang, Y., Xing, Y., Esqueda, M., Wei, Y., Cho, N. H., Kim, H. I., Kim, Y. S., Shelite, T. R., Cai, J., Sun, J., Bouyer, D. H., Liu, J. & Soong, L., Mar 1 2020, In : PLoS neglected tropical diseases. 14, 3, p. e0007675

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization

Ke, Y., Lv, X., Fu, X., Zhang, J., Bohio, A. A., Zeng, X., Hao, W., Wang, R., Boldogh, I. & Ba, X., 2020, (Accepted/In press) In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalArticle

Open Access

Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment

Cross, R. W., Bornholdt, Z. A., Prasad, A. N., Geisbert, J. B., Borisevich, V., Agans, K. N., Deer, D. J., Melody, K., Fenton, K. A., Feldmann, H., Sprecher, A., Zeitlin, L. & Geisbert, T. W., Dec 1 2020, In : Nature communications. 11, 1, 3736.

Research output: Contribution to journalArticle

Open Access

Prokaryotic Expression of the Immunoglobulin’s Domains of CRTAM to Characterize a Monoclonal Antibody

Barragan-Galvez, J. C., Gonzalez-Orozco, M., Hernandez-Flores, A., Maravillas-Montero, J. L., Chavez-Guerrero, Y. & Ortiz-Navarrete, V., Jun 1 2020, In : Protein Journal. 39, 3, p. 224-231 8 p.

Research output: Contribution to journalArticle

Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death

Cross, R. W., Xu, R., Matassov, D., Hamm, S., Latham, T. E., Gerardi, C. S., Nowak, R. M., Geisbert, J. B., Ota-Setlik, A., Agans, K. N., Luckay, A., Witko, S. E., Soukieh, L., Deer, D. J., Mire, C. E., Feldmann, H., Happi, C., Fenton, K. A., Eldridge, J. H. & Geisbert, T. W., Jan 2 2020, In : Journal of Clinical Investigation. 130, 1, p. 539-551 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Rational design of universal immunotherapy for TfR1-tropic arenaviruses

Cohen-Dvashi, H., Amon, R., Agans, K. N., Cross, R. W., Borenstein-Katz, A., Mateo, M., Baize, S., Padler-Karavani, V., Geisbert, T. W. & Diskin, R., Dec 1 2020, In : Nature communications. 11, 1, 67.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Resistance of Cynomolgus Monkeys to Nipah and Hendra Virus Disease Is Associated with Cell-Mediated and Humoral Immunity

Prasad, A. N., Woolsey, C., Geisbert, J. B., Agans, K. N., Borisevich, V., Deer, D. J., Mire, C. E., Cross, R. W., Fenton, K. A., Broder, C. C. & Geisbert, T. W., May 11 2020, In : Journal of Infectious Diseases. 221, p. S436-S447

Research output: Contribution to journalArticle

Open Access
2 Scopus citations