Research Output

Article

AAV2-mediated GRP78 transfer alleviates retinal neuronal injury by downregulating ER stress and Tau oligomer formation

Ha, Y., Liu, W., Liu, H., Zhu, S., Xia, F., Gerson, J. E., Azhar, N. A., Tilton, R., Motamedi, M., Kayed, R. & Zhang, W., Sep 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 11, p. 4670-4682 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau

Blair, L. J., Nordhues, B. A., Hill, S. E., Scaglione, K. M., O'Leary, J. C., Fontaine, S. N., Breydo, L., Zhang, B., Li, P., Wang, L., Cotman, C., Paulson, H. L., Muschol, M., Uversky, V. N., Klengel, T., Binder, E. B., Kayed, R., Golde, T. E., Berchtold, N. & Dickey, C. A., Oct 1 2013, In : Journal of Clinical Investigation. 123, 10, p. 4158-4169 12 p.

Research output: Contribution to journalArticle

114 Scopus citations

Acetyl-l-carnitine enhances the response of PC12 cells to nerve growth factor

Taglialatela, G., Angelucci, L., Ramacci, M. T., Werrbach-Perez, K., Jackson, G. R. & Perez-Polo, J. R., Apr 24 1991, In : Developmental Brain Research. 59, 2, p. 221-230 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice

Dineley, K. T., Hogan, D., Zhang, W. R. & Taglialatela, G., Sep 1 2007, In : Neurobiology of Learning and Memory. 88, 2, p. 217-224 8 p.

Research output: Contribution to journalArticle

105 Scopus citations

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Guerrero-Munoz, M. J., Kiritoshi, T., Neugebauer, V., Jackson, G. R. & Kayed, R., Nov 7 2012, In : Scientific reports. 2, 700.

Research output: Contribution to journalArticle

227 Scopus citations

Amelioration of hippocampal dysfunction by adipose tissue-targeted stem cell transplantation in a mouse model of type 2 diabetes

Krishnan, B., Sallam, H. S., Tumurbataar, B., Saieva, S., Baymon, DM., Tuvdendorj, D., Micci, M. A., Abate, N. & Taglialatela, G., Apr 1 2020, In : Journal of neurochemistry. 153, 1, p. 51-62 12 p.

Research output: Contribution to journalArticle

Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer’s disease

Baranello, R. J., Bharani, K. L., Padmaraju, V., Chopra, N., Lahiri, D. K., Greig, N. H., Pappolla, M. A. & Sambamurti, K., Oct 1 2015, In : Current Alzheimer Research. 12, 1, p. 32-46 15 p.

Research output: Contribution to journalArticle

117 Scopus citations

Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate

Yanamandra, K., Alexeyev, O., Zamotin, V., Srivastava, V., Shchukarev, A., Brorsson, A. C., Tartaglia, G. G., Vogl, T., Kayed, R., Wingsle, G., Olsson, J., Dobson, C. M., Bergh, A., Elgh, F. & Morozova-Roche, L. A., May 15 2009, In : PloS one. 4, 5, e5562.

Research output: Contribution to journalArticle

73 Scopus citations

Amyloid-β annular protofibrils evade fibrillar fate in Alzheimer disease brain

Lasagna-Reeves, C. A., Glabe, C. G. & Kayed, R., Jun 24 2011, In : Journal of Biological Chemistry. 286, 25, p. 22122-22130 9 p.

Research output: Contribution to journalArticle

96 Scopus citations

Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease

Guerrero-Muñoz, M. J., Castillo-Carranza, D. L., Krishnamurthy, S., Paulucci-Holthauzen, A. A., Sengupta, U., Lasagna-Reeves, C. A., Ahmad, Y., Jackson, G. R. & Kayed, R., Nov 2014, In : Neurobiology of Disease. 71, p. 14-23 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Amyloid-β oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice

Dineley, K. T., Kayed, R., Neugebauer, V., Fu, Y., Zhang, W., Reese, L. C. & Taglialatela, G., Oct 1 2010, In : Journal of Neuroscience Research. 88, 13, p. 2923-2932 10 p.

Research output: Contribution to journalArticle

74 Scopus citations

Amyloid-β peptide and oligomers in the brain and cerebrospinal fluid of aged canines

Head, E., Pop, V., Sarsoza, F., Kayed, R., Beckett, T. L., Studzinski, C. M., Tomic, J. L., Glabe, C. G. & Murphy, M. P., 2010, In : Journal of Alzheimer's Disease. 20, 2, p. 637-646 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

A native interactor scaffolds and stabilizes toxic Ataxin-1 oligomers in SCA1

Lasagna-Reeves, C. A., Rousseaux, M. W. C., Guerrero-Munoz, M. J., Park, J., Jafar-Nejad, P., Richman, R., Lu, N., Sengupta, U., Litvinchuk, A., Orr, H. T., Kayed, R. & Zoghbi, H. Y., May 19 2015, In : eLife. 4, MAY, p. 1-46 46 p.

Research output: Contribution to journalArticle

15 Scopus citations
23 Scopus citations

ApoE4-driven accumulation of intraneuronal oligomerized Aß42 following activation of the amyloid cascade in vivo is mediated by a gain of function

Zepa, L., Frenkel, M., Belinson, H., Kariv-Inbal, Z., Kayed, R., Masliah, E. & Michaelson, D. M., Apr 6 2011, In : International Journal of Alzheimer's Disease. 792070.

Research output: Contribution to journalArticle

21 Scopus citations

Approach to the comatose patient

Stevens, R. D. & Bhardwaj, A., Jan 2006, In : Critical care medicine. 34, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

82 Scopus citations

Ascorbic acid prevents β-amyloid-induced intracellular calcium increase and cell death in PC12 cells

Yallampalli, S., Micci, M. A. & Taglialatela, G., Jul 24 1998, In : Neuroscience Letters. 251, 2, p. 105-108 4 p.

Research output: Contribution to journalArticle

40 Scopus citations

Association of skin with the pathogenesis and treatment of neurodegenerative amyloidosis

Clos, A. L., Kayed, R. & Lasagna-Reeves, C. A., Sep 12 2012, In : Frontiers in Neurology. JAN, Article 5.

Research output: Contribution to journalArticle

10 Scopus citations

Astrocytes contain amyloid-β annular protofibrils in Alzheimer's disease brains

Lasagna-Reeves, C. A. & Kayed, R., Oct 3 2011, In : FEBS Letters. 585, 19, p. 3052-3057 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Azure C Targets and Modulates Toxic Tau Oligomers

Lo Cascio, F. & Kayed, R., Jun 20 2018, In : ACS Chemical Neuroscience. 9, 6, p. 1317-1326 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression

Portier, B. P. & Taglialatela, G., Dec 29 2006, In : Journal of Biological Chemistry. 281, 52, p. 40493-40502 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Bcl-2 phosphorylation is not required for its effects on NFκB activity

Massaad, C. A. & Taglialatela, G., Jun 11 2003, In : NeuroReport. 14, 8, p. 1167-1170 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Behavioural and neurological symptoms accompanied by cellular neuroinflammation in IL-10-deficient mice infected with Plasmodium chabaudi

Wilson, K. D., Stutz, S. J., Ochoa, L. F., Valbuena, G. A., Cravens, P. D., Dineley, K. T., Vargas, G. & Stephens, R., Aug 24 2016, In : Malaria Journal. 15, 1, 428.

Research output: Contribution to journalArticle

8 Scopus citations

Binding and neurotoxicity mitigation of toxic tau oligomers by synthetic heparin like oligosaccharides

Wang, P., Lo Cascio, F., Gao, J., Kayed, R. & Huang, X., Jan 1 2018, In : Chemical Communications. 54, 72, p. 10120-10123 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Blueberry supplemented diet: Effects on object recognition memory and nuclear factor-kappa B levels in aged rats

Goyarzu, P., Malin, D. H., Lau, F. C., Taglialatela, G., Moon, W. D., Jennings, R., Moy, E., Moy, D., Lippold, S., Shukitt-Hale, B. & Joseph, J. A., Apr 1 2004, In : Nutritional Neuroscience. 7, 2, p. 75-83 9 p.

Research output: Contribution to journalArticle

167 Scopus citations

Brain serum amyloid P levels are reduced in individuals that lack Dementia while having Alzheimer's disease neuropathology

Crawford, J. R., Gomer, R. H., Bjorklund, N. L. & Taglialatela, G., Apr 1 2012, In : Neurochemical Research. 37, 4, p. 795-801 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival

Mukherjee, A., Morales-Scheihing, D., Gonzalez-Romero, D., Green, K., Taglialatela, G. & Soto, C., Oct 1 2010, In : PLoS pathogens. 6, 10, e1001138.

Research output: Contribution to journalArticle

33 Scopus citations

Central nervous system DNA fragmentation induced by the inhibition of nuclear factor kappa B

Taglialatela, G., Kaufmann, J. A., Trevino, A. & Perez-Polo, J. R., Feb 16 1998, In : NeuroReport. 9, 3, p. 489-493 5 p.

Research output: Contribution to journalArticle

55 Scopus citations

Characterization of tau oligomeric seeds in progressive supranuclear palsy

Gerson, J. E., Sengupta, U., Lasagna-Reeves, C. A., Guerrero-Muñoz, M. J., Troncoso, J. & Kayed, R., Jan 27 2014, In : Acta Neuropathologica Communications. 2, 1, 73.

Research output: Contribution to journalArticle

39 Scopus citations

Cholesterol, oxidative stress, and Alzheimer's disease: Expanding the horizons of pathogenesis

Pappolla, M. A., Smith, M. A., Bryant-Thomas, T., Bazan, N., Petanceska, S., Perry, G., Thal, L. J., Sano, M. & Refolo, L. M., Jul 15 2002, In : Free Radical Biology and Medicine. 33, 2, p. 173-181 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Chronic poly-drug administration damages adult mouse brain neural stem cells

McGrath, E. L., Schlagal, C. R., Cortez, I., Dunn, T. J., Gao, J., Fox, R. G., Stutz, S. J., Kuo, Y. F., Hommel, J., Dineley, K., Cunningham, K., Kaphalia, B. & Wu, P., Nov 15 2019, In : Brain Research. 1723, 146425.

Research output: Contribution to journalArticle

Open Access

CK2α regulates the transcription of BRP in Drosophila

Wairkar, Y. P., Trivedi, D., Natarajan, R., Barnes, K., Dolores, L. & Cho, P., Dec 1 2013, In : Developmental Biology. 384, 1, p. 53-64 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cocaine withdrawal reduces group I mGluR-mediated long-term potentiation via decreased GABAergic transmission in the amygdala

Schmidt, K., Krishnan, B., Xia, Y., Sun, A., Orozco-Cabal, L., Pollandt, S., Centeno, M., Genzer, K., Gallagher, J. P., Shinnick-Gallagher, P. & Liu, J., Jul 1 2011, In : European Journal of Neuroscience. 34, 2, p. 177-189 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways

Denner, L. A., Rodriguez-Rivera, J., Haidacher, S. J., Jahrling, J. B., Carmical, J. R., Hernandez, C. M., Zhao, Y., Sadygov, R. G., Starkey, J. M., Spratt, H., Luxon, B. A., Wood, T. G. & Dineley, K. T., Nov 21 2012, In : Journal of Neuroscience. 32, 47, p. 16725-16735 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice

Nenov, M. N., Laezza, F., Haidacher, S. J., Zhao, Y., Sadygov, R. G., Starkey, J. M., Spratt, H., Luxon, B. A., Dineley, K. T. & Denner, L., Jan 20 2014, In : Journal of Neuroscience. 34, 3, p. 1028-1036 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression

Cole, A. R., Noble, W., Aalten, L. V., Plattner, F., Meimaridou, R., Hogan, D., Taylor, M., LaFrancois, J., Gunn-Moore, F., Verkhratsky, A., Oddo, S., Laferla, F., Giese, K. P., Dineley, K. T., Duff, K., Richardson, J. C., Yan, S. D., Hanger, D. P., Allan, S. M. & Sutherland, C., Nov 1 2007, In : Journal of neurochemistry. 103, 3, p. 1132-1144 13 p.

Research output: Contribution to journalArticle

122 Scopus citations

Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway

Shah, S. Z. A., Zhao, D., Taglialatela, G., Hussain, T., Dong, H., Sabir, N., Mangi, M. H., Wu, W., Lai, M., Zhang, X., Duan, Y., Wang, L., Zhou, X. & Yang, L., Mar 6 2019, In : International journal of molecular sciences. 20, 5

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Compression of lateral antebrachial cutaneous nerve in waitresses

Patel, C. & Vishnubhakat, S., Mar 6 2015, In : Journal of Clinical Neuromuscular Disease. 16, 3, p. 121-124 4 p.

Research output: Contribution to journalArticle

Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

Kayed, R., Canto, I., Breydo, L., Rasool, S., Lukacsovich, T., Wu, J., Albay, R., Pensalfini, A., Yeung, S., Head, E., Marsh, J. L. & Glabe, C., Dec 15 2010, In : Molecular Neurodegeneration. 5, 1, 57.

Research output: Contribution to journalArticle

97 Scopus citations

Co-occurrence of multiple sclerosis and myasthenia gravis: A case report and review of immunological theories

Dehbashi, S., Hamouda, D. & Shanina, E., Sep 1 2019, In : Multiple Sclerosis and Related Disorders. 34, p. 135-136 2 p.

Research output: Contribution to journalArticle

Open Access

Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features

Dansithong, W., Wolf, C. M., Sarkar, P., Paul, S., Chiang, A., Holt, I., Morris, G. E., Branco, D., Sherwood, M. C., Comai, L., Berul, C. I. & Reddy, S., Dec 18 2008, In : PloS one. 3, 12, e3968.

Research output: Contribution to journalArticle

32 Scopus citations

Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis

Chakraborty, A., Tapryal, N., Venkova, T., Mitra, J., Vasquez, V., Sarker, A. H., Duarte-Silva, S., Huai, W., Ashizawa, T., Ghosh, G., MacIel, P., Sarkar, P. S., Hegde, M. L., Chen, X. & Hazra, T. K., Apr 7 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 14, p. 8154-8165 12 p.

Research output: Contribution to journalArticle

Design of metastable β-sheet oligomers from natively unstructured peptide

Guerrero-Muñoz, M. J., Castillo-Carranza, D. L., Sengupta, U., White, M. A. & Kayed, R., Dec 18 2013, In : ACS chemical neuroscience. 4, 12, p. 1520-1523 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Developmental profile of the hypothalamo-pituitary-adrenal axis response to nerve growth factor

Taglialatela, G. & Perez-Polo, J. R., Dec 5 1994, In : Neuroscience Letters. 182, 2, p. 231-234 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Dexamethasone blocks nerve growth factor induction of nerve growth factor receptor mRNA in PC12 cells

Foreman, P. J., Taglialatela, G., Jackson, G. R. & Perez‐Polo, J. R., Jan 1992, In : Journal of Neuroscience Research. 31, 1, p. 52-57 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Differential activation of the ER stress factor XBP1 by oligomeric assemblies

Castillo-Carranza, D. L., Zhang, Y., Guerrero-Muñoz, M. J., Kayed, R., Rincon-Limas, D. E. & Fernandez-Funez, P., Aug 1 2012, In : Neurochemical Research. 37, 8, p. 1707-1717 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Distribution of carnosine-like peptides in the nervous system of developing and adult zebrafish (Danio rerio) and embryonic effects of chronic carnosine exposure

Senut, M. C., Azher, S., Margolis, F. L., Patel, K., Mousa, A. & Majid, A., Jul 1 2009, In : Cell and Tissue Research. 337, 1, p. 45-61 17 p.

Research output: Contribution to journalArticle

3 Scopus citations

Dopamine-induced plasticity, phospholipase D (PLD) activity and cocaine-cue behavior depend on PLD-linked metabotropic glutamate receptors in amygdala

Krishnan, B., Genzer, K. M., Pollandt, S. W., Liu, J., Gallagher, J. P. & Shinnick-Gallagher, P., Sep 27 2011, In : PloS one. 6, 9, e25639.

Research output: Contribution to journalArticle

15 Scopus citations