Research Output

2012

Gastrointestinal prophylaxis in neurocritical care

Schirmer, C. M., Kornbluth, J., Heilman, C. B. & Bhardwaj, A., Feb 1 2012, In : Neurocritical Care. 16, 1, p. 184-193 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Sarmiento, J., Troncoso, J., Jackson, G. R. & Kayed, R., May 1 2012, In : FASEB Journal. 26, 5, p. 1946-1959 14 p.

Research output: Contribution to journalArticle

208 Scopus citations

Identification of potential mediators of retinotopic mapping: A comparative proteomic analysis of optic nerve from WT and Phr1 retinal knockout mice

Lee, A. R., Lamb, R. R., Chang, J. H., Erdmann-Gilmore, P., Lichti, C. F., Rohrs, H. W., Malone, J. P., Wairkar, Y. P., Diantonio, A., Townsend, R. R. & Culican, S. M., Nov 2 2012, In : Journal of Proteome Research. 11, 11, p. 5515-5526 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2

Dey, S., Maiti, A. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Sarkar, P. S., Abdel-Rahman, S. Z., Sarker, A. H., Hang, B., Xie, J., Tomkinson, A. E., Zhou, M., Shen, B., Wang, G., Wu, C., Yu, D., Lin, D., Cardenas, V. & Hazra, T. K., Jun 1 2012, In : DNA Repair. 11, 6, p. 570-578 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Intra-arterial vasodilator use during endovascular therapy for acute ischemic stroke might improve reperfusion rate

El-Zammar, Z. M. K., Latorre, J. G. S., Wang, D., Satyan, S., Elnour, E., Kamel, A., Devasenapathy, A. & Lodi, Y. M., Sep 2012, In : Annals of the New York Academy of Sciences. 1268, 1, p. 134-140 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Molecular mechanisms of amyloid oligomers toxicity

Kayed, R. & Lasagna-Reeves, C. A., Dec 1 2012, Alzheimer'S Disease: Advances For A New Century. Perry, G., Zhu, X., Smith, M., Sorensen, A. & Avila, J. (eds.). p. 67-78 12 p. (Advances in Alzheimer's Disease; vol. 3).

Research output: Chapter in Book/Report/Conference proceedingChapter

16 Scopus citations

Myasthenia gravis: A review

Jayam Trouth, A., Dabi, A., Solieman, N., Kurukumbi, M. & Kalyanam, J., Dec 3 2012, In : Autoimmune Diseases. 1, 1, 874680.

Research output: Contribution to journalReview article

48 Scopus citations

Potential role of α-synuclein in neurodegeneration: Studies in a rat animal model

Stoica, G., Lungu, G., Bjorklund, N. L., Taglialatela, G., Zhang, X., Chiu, V., Hill, H. H., Schenk, J. O. & Murray, I., Aug 1 2012, In : Journal of neurochemistry. 122, 4, p. 812-822 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction

Mantha, A. K., Dhiman, M., Taglialatela, G., Perez-Polo, R. J. & Mitra, S., Jun 1 2012, In : Journal of Neuroscience Research. 90, 6, p. 1230-1239 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Role of human DNA glycosylase Nei-like 2 (NEIL2) and single strand break repair protein polynucleotide kinase 3′-phosphatase in maintenance of mitochondrial genome

Mandal, S. M., Hegde, M. L., Chatterjee, A., Hegde, P. M., Szczesny, B., Banerjee, D., Boldogh, I., Gao, R., Falkenberg, M., Gustafsson, C. M., Sarkar, P. S. & Hazra, T. K., Jan 20 2012, In : Journal of Biological Chemistry. 287, 4, p. 2819-2829 11 p.

Research output: Contribution to journalArticle

54 Scopus citations
28 Scopus citations

Surgical treatment of patients with Lennox-Gastaut syndrome phenotype

Liu, S. Y., An, N., Fang, X., Singh, P., Oommen, J., Yin, Q., Yang, M. H., Liu, Y., Liao, W., Gao, C. Q. & Yang, H., Jun 21 2012, In : The Scientific World Journal. 2012, 614263.

Research output: Contribution to journalArticle

10 Scopus citations

Tau protein: Function and pathology

Rosenmann, H., Blum, D., Kayed, R. & Ittner, L. M., Sep 19 2012, In : International Journal of Alzheimer's Disease. 707482.

Research output: Contribution to journalEditorial

4 Scopus citations

Transgenic mice with SCA10 pentanucleotide repeats show motor phenotype and susceptibility to seizure: A toxic RNA gain-of-function model

White, M., Xia, G., Gao, R., Wakamiya, M., Sarkar, P. S., McFarland, K. & Ashizawa, T., Mar 1 2012, In : Journal of Neuroscience Research. 90, 3, p. 706-714 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice

Rasool, S., Albay, R., Martinez-Coria, H., Breydo, L., Wu, J., Milton, S., Misra, S., Tran, A., Pensalfini, A., Laferla, F., Kayed, R. & Glabe, C. G., Aug 8 2012, In : Molecular Neurodegeneration. 7, 1, 37.

Research output: Contribution to journalArticle

28 Scopus citations

α7 nicotinic acetylcholine receptors in Alzheimer's disease: Neuroprotective, neurotrophic or both?

Hernandez, C. M. & Dineley, K. T., May 2012, In : Current Drug Targets. 13, 5, p. 613-622 10 p.

Research output: Contribution to journalArticle

54 Scopus citations

α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: Relevance to human synucleopathic diseases

Martin, Z. S., Neugebauer, V., Dineley, K. T., Kayed, R., Zhang, W., Reese, L. C. & Taglialatela, G., Feb 1 2012, In : Journal of neurochemistry. 120, 3, p. 440-452 13 p.

Research output: Contribution to journalArticle

56 Scopus citations
2011

Amyloid-β annular protofibrils evade fibrillar fate in Alzheimer disease brain

Lasagna-Reeves, C. A., Glabe, C. G. & Kayed, R., Jun 24 2011, In : Journal of Biological Chemistry. 286, 25, p. 22122-22130 9 p.

Research output: Contribution to journalArticle

96 Scopus citations

ApoE4-driven accumulation of intraneuronal oligomerized Aß42 following activation of the amyloid cascade in vivo is mediated by a gain of function

Zepa, L., Frenkel, M., Belinson, H., Kariv-Inbal, Z., Kayed, R., Masliah, E. & Michaelson, D. M., Apr 6 2011, In : International Journal of Alzheimer's Disease. 792070.

Research output: Contribution to journalArticle

21 Scopus citations

A role for calcineurin in Alzheimer's disease

Reese, L. C. & Taglialatela, G., Dec 1 2011, In : Current Neuropharmacology. 9, 4, p. 685-692 8 p.

Research output: Contribution to journalReview article

54 Scopus citations

Astrocytes contain amyloid-β annular protofibrils in Alzheimer's disease brains

Lasagna-Reeves, C. A. & Kayed, R., Oct 3 2011, In : FEBS Letters. 585, 19, p. 3052-3057 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Cocaine withdrawal reduces group I mGluR-mediated long-term potentiation via decreased GABAergic transmission in the amygdala

Schmidt, K., Krishnan, B., Xia, Y., Sun, A., Orozco-Cabal, L., Pollandt, S., Centeno, M., Genzer, K., Gallagher, J. P., Shinnick-Gallagher, P. & Liu, J., Jul 1 2011, In : European Journal of Neuroscience. 34, 2, p. 177-189 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dopamine-induced plasticity, phospholipase D (PLD) activity and cocaine-cue behavior depend on PLD-linked metabotropic glutamate receptors in amygdala

Krishnan, B., Genzer, K. M., Pollandt, S. W., Liu, J., Gallagher, J. P. & Shinnick-Gallagher, P., Sep 27 2011, In : PloS one. 6, 9, e25639.

Research output: Contribution to journalArticle

15 Scopus citations
52 Scopus citations

Evaluation of coma: A critical appraisal of popular scoring systems

Kornbluth, J. & Bhardwaj, A., Feb 1 2011, In : Neurocritical Care. 14, 1, p. 134-143 10 p.

Research output: Contribution to journalReview article

40 Scopus citations

Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast

Cherng, N., Shishkin, A. A., Schlager, L. I., Tuck, R. H., Sloan, L., Matera, R., Sarkar, P. S., Ashizawa, T., Freudenreich, C. H. & Mirkin, S. M., Feb 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 7, p. 2843-2848 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis

Clos, A. L., Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Jackson, G. R., Kelly, B., Beachkofsky, T. M. & Kayed, R., Dec 1 2011, In : British Journal of Dermatology. 165, 6, p. 1349-1354 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation

Zhao, Y., Banerjee, S., Dey, N., LeJeune, W. S., Sarkar, P. S., Brobey, R., Rosenblatt, K. P., Tilton, R. G. & Choudhary, S., Jul 1 2011, In : Diabetes. 60, 7, p. 1907-1916 10 p.

Research output: Contribution to journalArticle

115 Scopus citations

Myotonic dystrophy types 1 and 2

Ashizawa, T. & Sarkar, P. S., Apr 22 2011, In : Handbook of Clinical Neurology. 101, p. 193-237 45 p.

Research output: Contribution to journalArticle

53 Scopus citations

Preferential repair of oxidized base damage in the transcribed genes of mammalian cells

Banerjee, D., Mandal, S. M., Das, A., Hegde, M. L., Das, S., Bhakat, K. K., Boldogh, I., Sarkar, P. S., Mitra, S. & Hazra, T. K., Feb 25 2011, In : Journal of Biological Chemistry. 286, 8, p. 6006-6016 11 p.

Research output: Contribution to journalArticle

87 Scopus citations

Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease

Parri, H. R., Hernandez, C. M. & Dineley, K. T., Oct 15 2011, In : Biochemical Pharmacology. 82, 8, p. 931-942 12 p.

Research output: Contribution to journalArticle

125 Scopus citations

RNA Foci, CUGBP1, and ZNF9 are the primary targets of the mutant CUG and CCUG repeats expanded in myotonic dystrophies type 1 and type 2

Jones, K., Jin, B., Iakova, P., Huichalaf, C., Sarkar, P., Schneider-Gold, C., Schoser, B., Meola, G., Shyu, A. B., Timchenko, N. & Timchenko, L., Nov 1 2011, In : American Journal of Pathology. 179, 5, p. 2475-2489 15 p.

Research output: Contribution to journalArticle

23 Scopus citations

Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis

Clos, A. L., Lasagna-Reeves, C. A., Kelly, B., Wagner, R., Wilkerson, M., Jackson, G. R. & Kayed, R., Nov 1 2011, In : Journal of the American Academy of Dermatology. 65, 5, p. 1023-1031 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status

Rodriguez-Rivera, J., Denner, L. & Dineley, K. T., Jan 1 2011, In : Behavioural Brain Research. 216, 1, p. 255-261 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

Tau oligomers as potential targets for immunotherapy for alzheimer's disease and tauopathies

Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Jackson, G. R. & Kayed, R., Sep 1 2011, In : Current Alzheimer Research. 8, 6, p. 659-665 7 p.

Research output: Contribution to journalArticle

54 Scopus citations

Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Clos, A. L., Jackson, G. R. & Kayed, R., Jun 8 2011, In : Molecular Neurodegeneration. 6, 1, 39.

Research output: Contribution to journalArticle

235 Scopus citations

Vasoactive intestinal peptide re-balances TREM-1/TREM-2 ratio in acute lung injury

Sun, G. Y., Guan, C. X., Zhou, Y., Liu, Y. P., Li, S. F., Zhou, H. F., Tang, C. Y. & Fang, X., Feb 25 2011, In : Regulatory Peptides. 167, 1, p. 56-64 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2010

Amyloid-β oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice

Dineley, K. T., Kayed, R., Neugebauer, V., Fu, Y., Zhang, W., Reese, L. C. & Taglialatela, G., Oct 1 2010, In : Journal of Neuroscience Research. 88, 13, p. 2923-2932 10 p.

Research output: Contribution to journalArticle

74 Scopus citations

Amyloid-β peptide and oligomers in the brain and cerebrospinal fluid of aged canines

Head, E., Pop, V., Sarsoza, F., Kayed, R., Beckett, T. L., Studzinski, C. M., Tomic, J. L., Glabe, C. G. & Murphy, M. P., 2010, In : Journal of Alzheimer's Disease. 20, 2, p. 637-646 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Anti-tau oligomers passive vaccination for the treatment of Alzheimer disease

Kayed, R., Nov 1 2010, In : Human Vaccines. 6, 11, p. 931-935 5 p.

Research output: Contribution to journalReview article

30 Scopus citations
23 Scopus citations

Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival

Mukherjee, A., Morales-Scheihing, D., Gonzalez-Romero, D., Green, K., Taglialatela, G. & Soto, C., Oct 1 2010, In : PLoS pathogens. 6, 10, e1001138.

Research output: Contribution to journalArticle

33 Scopus citations

Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

Kayed, R., Canto, I., Breydo, L., Rasool, S., Lukacsovich, T., Wu, J., Albay, R., Pensalfini, A., Yeung, S., Head, E., Marsh, J. L. & Glabe, C., Dec 15 2010, In : Molecular Neurodegeneration. 5, 1, 57.

Research output: Contribution to journalArticle

97 Scopus citations

Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal

Krishnan, B., Centeno, M., Pollandt, S., Fu, Y., Genzer, K., Liu, J., Gallagher, J. P. & Shinnick-Gallagher, P., Mar 1 2010, In : European Journal of Neuroscience. 31, 6, p. 1027-1042 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

Following activation of the amyloid cascade, apolipoprotein e4 drives the in vivo oligomerization of amyloid-β resulting in neurodegeneration

Belinson, H., Kariv-Inbal, Z., Kayed, R., Masliah, E. & Michaelson, D. M., 2010, In : Journal of Alzheimer's Disease. 22, 3, p. 959-970 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Inactivation of hnRNP K by expanded intronic AUUCU repeat induces apoptosis via translocation of PKCδ to mitochondria in spinocerebellar ataxia 10

White, M. C., Gao, R., Xu, W., Mandal, S. M., Lim, J. G., Hazra, T. K., Wakamiya, M., Edwards, S. F., Raskin, S., Teive, H. A. G., Zoghbi, H. Y., Sarkar, P. S. & Ashizawa, T., Jun 1 2010, In : PLoS genetics. 6, 6, p. 1-12 12 p.

Research output: Contribution to journalArticle

79 Scopus citations

Inhaled insulin forms toxic pulmonary amyloid aggregates

Lasagna-Reeves, C. A., Clos, A. L., Midoro-Hiriuti, T., Goldblum, R. M., Jackson, G. R. & Kayed, R., Oct 2010, In : Endocrinology. 151, 10, p. 4717-4724 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
144 Scopus citations

Management strategies in chronic inflammatory demyelinating polyradiculoneuropathy

Patel, K., Bhanushali, M. & Muley, S. A., Jul 1 2010, In : Neurology India. 58, 3, p. 351-360 10 p.

Research output: Contribution to journalReview article

3 Scopus citations

Neuroimmunomodulation by calcineurin in aging and Alzheimer's disease

Reese, L. C. & Taglialatela, G., Jan 1 2010, In : Aging and Disease. 1, 3, p. 245-253 9 p.

Research output: Contribution to journalReview article

11 Scopus citations