Research Output 1965 2019

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2019

A De novo HDAC2 variant in a patient with features consistent with Cornelia de Lange syndrome phenotype

Wagner, V. F., Hillman, P. R., Britt, A. D., Ray, J. & Farach, L. S., May 1 2019, In : American Journal of Medical Genetics, Part A. 179, 5, p. 852-856 5 p.

Research output: Contribution to journalArticle

Histone Deacetylase 2
De Lange Syndrome
Phenotype
Histone Deacetylase 1
Genes
1 Citation (Scopus)

A dose ranging study of 2 different formulations of 15-valent pneumococcal conjugate vaccine (PCV15) in healthy infants

Rupp, R., Hurley, D., Grayson, S., Li, J., Nolan, K., McFetridge, R. D., Hartzel, J., Abeygunawardana, C., Winters, M., Pujar, H., Benner, P. & Musey, L., Mar 4 2019, In : Human Vaccines and Immunotherapeutics. 15, 3, p. 549-559 11 p.

Research output: Contribution to journalArticle

Conjugate Vaccines
Pneumococcal Vaccines
Polysaccharides
Immunoglobulin G
Antibody Formation

An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses

Li, G., Adam, A., Luo, H., Shan, C., Cao, Z., Fontes-Garfias, C. R., Sarathy, V. V., Teleki, C., Winkelmann, E. R., Liang, Y., Sun, J., Bourne, N., Barrett, A. D. T., Shi, P. Y. & Wang, T., Dec 1 2019, In : npj Vaccines. 4, 1, 48.

Research output: Contribution to journalArticle

Open Access
Mutant Proteins
Antiviral Agents
Attenuated Vaccines
Flavivirus
Zika Virus
Open Access
Hypertrophy
Extremities
Port-Wine Stain
Polydactyly
Varicose Veins
Medical Students
Counseling
Vaccination
Papillomavirus Vaccines
Students

Antenatal Magnesium Sulfate Exposure and Hemodynamically Significant Patent Ductus Arteriosus in Premature Infants

Qasim, A., Jain, S. K. & Aly, A. M., Jan 1 2019, In : AJP Reports. 9, 4, p. e353-e356

Research output: Contribution to journalArticle

Open Access
Magnesium Sulfate
Patent Ductus Arteriosus
Premature Infants
Research Design
Steroids

Antiviral and immunomodulatory activity of silver nanoparticles in experimental rsv infection

Morris, D., Ansar, M., Speshock, J., Ivanciuc, T., Qu, Y., Casola, A. & Garofalo, R., Aug 1 2019, In : Viruses. 11, 8, 732.

Research output: Contribution to journalArticle

Open Access
Respiratory Syncytial Viruses
Silver
Nanoparticles
Antiviral Agents
Respiratory Syncytial Virus Infections

A Replication-Defective Human Cytomegalovirus Vaccine Elicits Humoral Immune Responses Analogous to Those with Natural Infection

Liu, Y., Freed, D. C., Li, L., Tang, A., Li, F., Murray, E. M., Adler, S. P., McVoy, M. A., Rupp, R. E., Barrett, D., Ye, X., Zhang, N., Beck, K., Culp, T., Das, R., Song, L., Vora, K., Zhu, H., Wang, D., Espeseth, A. S. & 3 others, An, Z., Musey, L. & Fu, T. M., Dec 1 2019, In : Journal of virology. 93, 23

Research output: Contribution to journalArticle

Cytomegalovirus Vaccines
Human herpesvirus 5
Humoral Immunity
humoral immunity
Cytomegalovirus

Attenuation of zika virus by passage in human HeLa cells

Li, L., Collins, N. D., Widen, S. G., Davis, E. H., Kaiser, J. A., White, M. M., Greenberg, M. B., Barrett, A. D. T., Bourne, N. & Sarathy, V. V., Sep 2019, In : Vaccines. 7, 3, 93.

Research output: Contribution to journalArticle

Open Access
HeLa Cells
Flavivirus
Culicidae
Viremia
Japanese Encephalitis
1 Citation (Scopus)
Patient Navigation
Program Evaluation
Caregivers
Vaccination
Pediatrics

Case 4: Large-Volume Hematemesis in a 16-year-old Boy

Dasgupta, S., Olaloye, O. O., Pierce, M. A. & Glaser, A. M., Oct 1 2019, In : Pediatrics in review. 40, 10, p. 538-542 5 p.

Research output: Contribution to journalArticle

Hematemesis
Open Access
Cystatin C
Klebsiella pneumoniae
Cystatins
Biomarkers
Inflammation

Co-occurring defect analysis: A platform for analyzing birth defect co-occurrence in registries

Benjamin, R. H., Yu, X., Navarro Sanchez, M. L., Chen, H., Mitchell, L. E., Langlois, P. H., Canfield, M. A., Swartz, M. D., Scheuerle, A. E., Scott, D. A., Northrup, H., Schaaf, C. P., Ray, J. W., McLean, S. D., Lupo, P. J. & Agopian, A. J., Nov 1 2019, In : Birth Defects Research. 111, 18, p. 1356-1364 9 p.

Research output: Contribution to journalArticle

Open Access
Registries
Defects
Spinal Dysraphism
Down Syndrome
Medical Records
1 Citation (Scopus)

Cultivated human vaginal microbiome communities impact zika and herpes simplex virus replication in ex vivovaginal mucosal cultures

Amerson-Brown, M. H., Miller, A. L., Maxwell, C. A., White, M. M., Vincent, K., Bourne, N. & Pyles, R., Jan 1 2019, In : Frontiers in Microbiology. 10, JAN, 03340.

Research output: Contribution to journalArticle

Open Access
Microbiota
Simplexvirus
Virus Replication
Epithelial Cells
Viral Load
Cystathionine
Lyases
Virus Diseases
Smoke
Tobacco

Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo

Banasik, B. N., Perry, C. L., Keith, C. A., Bourne, N., Schäfer, H. & Milligan, G., Jan 1 2019, (Accepted/In press) In : Journal of Immunological Methods. 112654.

Research output: Contribution to journalArticle

Guinea Pigs
Monoclonal Antibodies
T-Lymphocytes
Active Immunotherapy
Investigational Therapies

Development of a novel ex vivo nasal epithelial cell model supporting colonization with human nasal microbiota

Charles, D. D., Fisher, J. R., Hoskinson, S. M., Medina-Colorado, A. A., Shen, Y. C., Chaaban, M., Widen, S., Eaves-Pyles, T., Maxwell, C. A., Miller, A. L., Popov, V. & Pyles, R., Jan 1 2019, In : Frontiers in Cellular and Infection Microbiology. 9, MAY, 165.

Research output: Contribution to journalArticle

Open Access
Microbiota
Nose
Epithelial Cells
Air
Tissue Donors

Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2

Bourne, N., Banasik, B. N., Perry, C. L., Miller, A. L., White, M., Pyles, R. & Milligan, G., Jan 2 2019, In : Virology. 526, p. 180-188 9 p.

Research output: Contribution to journalArticle

Human Herpesvirus 2
Virus Shedding
Foreskin
Perineum
Immunity
Hyperlipoproteinemia Type I
Plasma Exchange
Pancreatitis
Hypertriglyceridemia
Incidence

Genotypic and phenotypic variability of 22q11.2 microduplications: An institutional experience

Yu, A., Turbiville, D., Xu, F., Ray, J., Britt, A. D., Lupo, P., Jain, S., Shattuck, K., Robinson, S. S. & Dong, J., Jan 1 2019, (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

Cardiovascular Abnormalities
Phenotype
Central Nervous System
Parturition
Newborn Infant

Human metapneumovirus infection of airway epithelial cells is associated with changes in core metabolic pathways

Zhao, Y., Chahar, H. S., Komaravelli, N., Dossumekova, A. & Casola, A., May 1 2019, In : Virology. 531, p. 183-191 9 p.

Research output: Contribution to journalArticle

Metapneumovirus
Metabolic Networks and Pathways
Epithelial Cells
Infection
Hexokinase
2 Citations (Scopus)

Increased frequency of virus shedding by herpes simplex virus 2-infected Guinea pigs in the absence of CD4 T lymphocytes

Bourne, N., Perry, C. L., Banasik, B. N., Miller, A. L., White, M., Pyles, R., Schäfer, H. & Milligan, G., Feb 1 2019, In : Journal of Virology. 93, 4, e0172118.

Research output: Contribution to journalArticle

Human herpesvirus 2
Virus Shedding
viral shedding
Human Herpesvirus 2
guinea pigs

L-Cysteine supplementation prevents liver transplantation in a patient with TRMU deficiency

Soler-Alfonso, C., Pillai, N., Cooney, E., Mysore, K. R., Boyer, S. & Scaglia, F., Jun 1 2019, In : Molecular Genetics and Metabolism Reports. 19, 100453.

Research output: Contribution to journalArticle

Open Access
Transfer RNA
Liver Transplantation
Cysteine
Sulfur
Electron Transport

Lyophilization of human amniotic fluid is feasible without affecting biological activity

Coon, J. I., Jain, S., Sepuru, K. M., Chung, Y., Mohankumar, K., Rajarathnam, K. & Jain, S. K., Jan 1 2019, (Accepted/In press) In : Pediatric Research.

Research output: Contribution to journalArticle

Freeze Drying
Amniotic Fluid
Interleukin-8
Deglutition
Dialysis

Management of late preterm and term neonates exposed to maternal chorioamnionitis

Sahni, M., Franco-Fuenmayor, M. E. & Shattuck, K., Aug 13 2019, In : BMC Pediatrics. 19, 1, 282.

Research output: Contribution to journalArticle

Open Access
Chorioamnionitis
Mothers
Newborn Infant
Anti-Bacterial Agents
Blood Cell Count

Microbiota of the Oropharynx and Endoscope Compared to the Esophagus

Okereke, I., Miller, A. L., Hamilton, C. F., Booth, A. L., Reep, G., Andersen, C. L., Reynolds, S. T. & Pyles, R., Dec 1 2019, In : Scientific reports. 9, 1, 10201.

Research output: Contribution to journalArticle

Open Access
Oropharynx
Endoscopes
Microbiota
Esophagus
Uvula

Microflora composition in the gastrointestinal tract in patients with Barrett's esophagus

Okereke, I., Hamilton, C., Reep, G., Krill, T., Booth, A., Ghouri, Y., Jala, V., Andersen, C. & Pyles, R., Jan 1 2019, In : Journal of Thoracic Disease. 11, p. S1581-S1587

Research output: Contribution to journalArticle

Barrett Esophagus
Esophagus
Gastrointestinal Tract
Endoscopes
Uvula

Omega-3 polyunsaturated fatty acids have beneficial effects on visceral fat in diet-induced obesity model

de Mello, A. H., Schraiber, R. D. B., Goldim, M. P. D. S., Mathias, K., Mendes, C., Corrêa, M. E. A. B., Gomes, M. L., Silveira, P. C. L., Schuck, P. F., Petronilho, F. & Rezin, G. T., Jan 1 2019, In : Biochemistry and Cell Biology. 97, 6, p. 693-701 9 p.

Research output: Contribution to journalArticle

Intra-Abdominal Fat
Omega-3 Fatty Acids
Nutrition
Unsaturated Fatty Acids
Obesity

Perspectives on the management of children in a biocontainment unit: Report of the NETEC pediatric workgroup

Cieslak, T. J., Evans, L., Kortepeter, M. G., Grindle, A., Aigbivbalu, L., Boulter, K., Carroll, R. W., Cumplido, S., Danforth, A. G., Fry, C., Gaensbauer, J., Hume, J. R., Husain, A., Kelleher, A., Kratochvil, C. J., Kunrath, C., Morgan, J. S., Schwedhelm, M. M., Shane, A. L., Tennill, P. & 2 others, Yager, P. H. & Davies, H. D., Jan 1 2019, In : Health Security. 17, 1, p. 11-17 7 p.

Research output: Contribution to journalArticle

Pediatrics
containment
education and training
Ebola Hemorrhagic Fever
Viruses
1 Citation (Scopus)

Phase 1 Clinical Trial of a Conditionally Replication-Defective Human Cytomegalovirus (CMV) Vaccine in CMV-Seronegative Subjects

Adler, S. P., Lewis, N., Conlon, A., Christiansen, M. P., Al-Ibrahim, M., Rupp, R., Fu, T. M., Bautista, O., Tang, H., Wang, D., Fisher, A., Culp, T., Das, R., Beck, K., Tamms, G. & Musey, L., Jul 2 2019, In : Journal of Infectious Diseases. 220, 3, p. 411-419 9 p., jiz141.

Research output: Contribution to journalArticle

Cytomegalovirus Vaccines
Clinical Trials, Phase I
Cytomegalovirus
Virus Shedding
Vaccines

Physiologically-Based Pharmacokinetic Modeling of Fluconazole Using Plasma and Cerebrospinal Fluid Samples From Preterm and Term Infants

the Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee, Jan 1 2019, In : CPT: Pharmacometrics and Systems Pharmacology.

Research output: Contribution to journalArticle

Open Access
Cerebrospinal fluid
Pharmacokinetics
Fluconazole
Premature Infants
Cerebrospinal Fluid
2 Citations (Scopus)

Pollen food allergy syndrome to tomato in mountain cedar pollen hypersensitivity

Bonds, R., Sharma, G. S., Kondo, Y., van Bavel, J., Goldblum, R. M. & Midoro-Horiuti, T., Jul 1 2019, In : Molecular Immunology. 111, p. 83-86 4 p.

Research output: Contribution to journalArticle

Seasonal Allergic Rhinitis
Food Hypersensitivity
Lycopersicon esculentum
Pollen
Hypersensitivity

Prenatal vaccination of mothers and hepatitis B vaccination of their infants

Fuchs, E., Starkey, J., Rupp, R. & Berenson, A., Apr 1 2019, In : Preventive Medicine. 121, p. 68-73 6 p.

Research output: Contribution to journalArticle

Hepatitis B
Vaccination
Mothers
Whooping Cough
Diphtheria

Regional variations in human papillomavirus prevalence across time in NHANES (2003–2014)

Hirth, J., Kuo, Y. F., Starkey, J., Rupp, R., Laz, T. H., Rahman, M. & Berenson, A., Jan 1 2019, In : Vaccine.

Research output: Contribution to journalArticle

National Health and Nutrition Examination Survey
Papillomaviridae
Nutrition Surveys
Papillomavirus Vaccines
Licensure

The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis

Ahmad, A., Vieira, J. D. C., Haas de Mello, A., de Lima, T. M., Ariga, S. K., Barbeiro, D. F., Barbeiro, H. V., Szczesny, B., Törö, G., Druzhyna, N., Randi, E. B., Marcatti, M., Toliver-Kinsky, T., Kiss, A., Liaudet, L., Salomao, R., Soriano, F. G. & Szabo, C., Jul 1 2019, In : Pharmacological Research. 145, 104263.

Research output: Contribution to journalArticle

Investigational Therapies
Punctures
Ligation
Sepsis
Oxidative Stress

Wharton’s Jelly Mesenchymal Stromal Cells from Human Umbilical Cord: a Close-up on Immunomodulatory Molecules Featured In Situ and In Vitro

Corsello, T., Amico, G., Corrao, S., Anzalone, R., Timoneri, F., Lo Iacono, M., Russo, E., Spatola, G. F., Uzzo, M. L., Giuffrè, M., Caprnda, M., Kubatka, P., Kruzliak, P., Conaldi, P. G. & La Rocca, G., Jan 1 2019, (Accepted/In press) In : Stem Cell Reviews and Reports.

Research output: Contribution to journalArticle

Wharton Jelly
Umbilical Cord
Mesenchymal Stromal Cells
Mixed Lymphocyte Culture Test
Regenerative Medicine
2018
1 Citation (Scopus)

Acculturation, Cultural Values, and Breastfeeding in Overweight or Obese, Low-Income, Hispanic Women at 1 Month Postpartum

Shin, C. N., Reifsnider, E., McClain, D., Jeong, M., McCormick, D. P. & Moramarco, M., Mar 1 2018, (Accepted/In press) In : Journal of Human Lactation.

Research output: Contribution to journalArticle

Acculturation
Breast Feeding
Hispanic Americans
Postpartum Period
Randomized Controlled Trials
1 Citation (Scopus)

Achieving high HPV vaccine completion rates in a pediatric clinic population

Berenson, A. B., Rupp, R., Dinehart, E. E., Cofie, L. E., Kuo, Y. F. & Hirth, J. M., Jan 1 2018, (Accepted/In press) In : Human Vaccines and Immunotherapeutics.

Research output: Contribution to journalArticle

Patient Navigation
Papillomavirus Vaccines
Pediatrics
Vaccination
Population
7 Citations (Scopus)

A phase 1 study of safety and immunogenicity following intradermal administration of a tetravalent dengue vaccine candidate

Jackson, L. A., Rupp, R., Papadimitriou, A., Wallace, D., Raanan, M. & Moss, K. J., Jan 1 2018, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

Dengue Vaccines
dengue
immune response
vaccines
Safety
23 Citations (Scopus)

Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development review-article

Hallam, H. J., Hallam, S., Rodriguez, S., Barrett, A., Beasley, D., Chua, A., Ksiazek, T., Milligan, G., Sathiyamoorthy, V. & Reece, L. M., Dec 1 2018, In : npj Vaccines. 3, 1, 11.

Research output: Contribution to journalArticle

Lassa Fever
Lassa virus
Virology
Epidemiology
Vaccines
7 Citations (Scopus)

Central role of the NF-κB pathway in the Scgb1a1-expressing epithelium in mediating respiratory syncytial virus-induced airway inflammation

Tian, B., Yang, J., Zhao, Y., Ivanciuc, T., Sun, H., Wakamiya, M., Garofalo, R. & Brasier, A. R., Jun 1 2018, In : Journal of Virology. 92, 11, e00441-18.

Research output: Contribution to journalArticle

respiratory mucosa
Respiratory Syncytial Virus Infections
Respiratory Syncytial Viruses
Knockout Mice
Interferons
4 Citations (Scopus)

Characterization of a murine model of non-lethal, symptomatic dengue virus infection

Sarathy, V., White, M., Li, L., Kaiser, J. A., Campbell, G., Milligan, G., Bourne, N. & Barrett, A., Dec 1 2018, In : Scientific Reports. 8, 1, 4900.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
Infection
Dengue
Severe Dengue
1 Citation (Scopus)

Defining a correlate of protection for chikungunya virus vaccines

Milligan, G., Schnierle, B. S., McAuley, A. J. & Beasley, D., Jan 1 2018, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

Chikungunya virus
Vaccines
Clinical Trials
vaccines
complications (disease)

Early childhood attachment and suicidal ideation among young Kenyan men

Goodman, M., Gibson, D., Vo, T. T., Wang, A., Gitari, S. & Raimer, B., Mar 1 2018, In : Advances in Life Course Research. 35, p. 126-134 9 p.

Research output: Contribution to journalArticle

suicide
childhood
adulthood
present

Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection

Choi, E-J., Ren, Y., Chen, Y., Liu, S., Wu, W., Ren, J., Wang, P., Garofalo, R., Zhou, J. & Bao, X., Nov 15 2018, In : Journal of Virology. 92, 22

Research output: Contribution to journalArticle

Respiratory Syncytial Virus Infections
Respiratory Syncytial Viruses
viruses
virus replication
infection
9 Citations (Scopus)

Expression of programmed death-ligand 1 by human colonic CD90+ stromal cells differs between ulcerative colitis and Crohn's disease and determines their capacity to suppress Th1 cells

Beswick, E. J., Grim, C., Singh, A., Aguirre, J. E., Tafoya, M., Qiu, S., Rogler, G., McKee, R., Samedi, V., Ma, T. Y., Reyes, V., Powell, D. W. & Pinchuk, I., May 30 2018, In : Frontiers in Immunology. 9, MAY, 1125.

Research output: Contribution to journalArticle

Th1 Cells
Stromal Cells
Ulcerative Colitis
Crohn Disease
Fibroblasts
2 Citations (Scopus)

High-sensitivity troponin T in preterm infants with a hemodynamically significant patent ductus arteriosus

Asrani, P., Aly, A., Jiwani, A., Niebuhr, B. R., Christenson, R. H. & Jain, S., Jan 1 2018, (Accepted/In press) In : Journal of Perinatology.

Research output: Contribution to journalArticle

Troponin T
Patent Ductus Arteriosus
Premature Infants
Birth Weight
Regression Analysis

Hyaline membrane disease (HMD): an historical and Oslerian perspective

Malloy, M. & McGovern, J. P., Jan 1 2018, (Accepted/In press) In : Journal of Perinatology.

Research output: Contribution to journalArticle

Hyaline Membrane Disease
Infant Mortality
Surface-Active Agents
Pharmacology
2 Citations (Scopus)
Papillomavirus Vaccines
Papillomaviridae
anthropogenic activities
Vaccination
vaccination
2 Citations (Scopus)

Incidental Hypercalcemia Caused by Primary Hyperparathyroidism with Rapid Progression to Renal Complications in a Child

Tosur, M., Patel, K. N., Swischuk, L. E. & Lee, P., Jan 1 2018, In : Clinical Pediatrics. 57, 1, p. 117-120 4 p.

Research output: Contribution to journalArticle

Primary Hyperparathyroidism
Hypercalcemia
Kidney