Abha Sahni, PhD, MS

  • 1609 Citations
  • 20 h-Index
19982020

Research output per year

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Research Output

  • 1609 Citations
  • 20 h-Index
  • 45 Article
  • 2 Chapter
  • 2 Review article
  • 1 Letter
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Article
2020
Open Access

Comparative transcriptomic analysis of Rickettsia conorii during in vitro infection of human and tick host cells

Narra, H. P., Sahni, A., Alsing, J., Schroeder, C. L. C., Golovko, G., Nia, A. M., Fofanov, Y., Khanipov, K. & Sahni, S. K., Sep 25 2020, In : BMC Genomics. 21, 1, p. 665 1 p.

Research output: Contribution to journalArticle

Open Access

Evolution, purification, and characterization of rc0497: A peptidoglycan amidase from the prototypical spotted fever species rickettsia conorii

Patel, J. G., Narra, H. P., Sepuru, K. M., Sahni, A., Golla, S. R., Sahni, A., Singh, A., Schroeder, C. L. C., Chowdhury, I. H., Popov, V. L. & Sahni, S. K., Feb 1 2020, In : Biological Chemistry. 401, 2, p. 249-262 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Enhancer associated long non-coding RNA transcription and gene regulation in experimental models of rickettsial infection

Chowdhury, I. H., Narra, H. P., Sahni, A., Khanipov, K., Fofanov, Y. & Sahni, S. K., 2019, In : Frontiers in immunology. 10, JAN, 3014.

Research output: Contribution to journalArticle

2 Scopus citations

Global transcriptomic profiling of pulmonary gene expression in an experimental murine model of Rickettsia conorii infection

Narra, H. P., Sahni, A., Khanipov, K., Fofanov, Y. & Sahni, S. K., Mar 2019, In : Genes. 10, 3, 204.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Rickettsia rickettsii whole-cell antigens offer protection against rocky mountain spotted fever in the canine host

Alhassan, A., Liu, H., McGill, J., Cerezo, A., Jakkula, L. U. M. R., Nair, A. D. S., Winkley, E., Olson, S., Marlow, D., Sahni, A., Narra, H. P., Sahni, S., Henningson, J. & Ganta, R. R., Feb 1 2019, In : Infection and immunity. 87, 2, e0062818.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Expression Profiling of Long Noncoding RNA Splice Variants in Human Microvascular Endothelial Cells: Lipopolysaccharide Effects in Vitro

Chowdhury, I. H., Narra, H. P., Sahni, A., Khanipov, K., Schroeder, C. L. C., Patel, J., Fofanov, Y. & Sahni, S. K., 2017, In : Mediators of inflammation. 2017, 3427461.

Research output: Contribution to journalArticle

10 Scopus citations

Fibroblast growth factor receptor-1 mediates internalization of pathogenic spotted fever rickettsiae into host endothelium

Sahni, A., Patel, J., Narra, H. P., Schroeder, C. L. C., Walker, D. H. & Sahni, S. K., Aug 2017, In : PloS one. 12, 8, e0183181.

Research output: Contribution to journalArticle

6 Scopus citations

MicroRNA signature of human microvascular endothelium infected with Rickettsia rickettsii

Sahni, A., Narra, H. P., Patel, J. & Sahni, S. K., Jul 9 2017, In : International journal of molecular sciences. 18, 7, 1471.

Research output: Contribution to journalArticle

5 Scopus citations

Transcriptional profiling of Rickettsia prowazekii coding and non-coding transcripts during in vitro host-pathogen and vector-pathogen interactions

Schroeder, C. L. C., Narra, H. P., Sahni, A., Khanipov, K., Patel, J., Fofanov, Y. & Sahni, S. K., Oct 2017, In : Ticks and Tick-borne Diseases. 8, 6, p. 827-836 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Bortezomib Effects on Human Microvascular Endothelium in vitro

Sahni, A., Thomasson, E. D., Shah, R. & Sahni, S., Aug 27 2016, (Accepted/In press) In : Pharmacology. p. 272-278 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Identification and characterization of novel small RNAs in Rickettsia prowazekii

Schroeder, C. L. C., Narra, H. P., Sahni, A., Rojas, M., Khanipov, K., Patel, J., Shah, R., Fofanov, Y. & Sahni, S. K., 2016, In : Frontiers in Microbiology. 7, JUN, 859.

Research output: Contribution to journalArticle

11 Scopus citations

Small Regulatory RNAs of Rickettsia conorii

Narra, H. P., Schroeder, C. L. C., Sahni, A., Rojas, M., Khanipov, K., Fofanov, Y. & Sahni, S. K., Nov 11 2016, In : Scientific reports. 6, 36728.

Research output: Contribution to journalArticle

15 Scopus citations
2015

Bacterial small RNAs in the Genus Rickettsia

Schroeder, C. L. C., Narra, H. P., Rojas, M., Sahni, A., Patel, J., Khanipov, K., Wood, T. G., Fofanov, Y. & Sahni, S. K., Dec 18 2015, In : BMC Genomics. 16, 1, 1075.

Research output: Contribution to journalArticle

19 Scopus citations
2013
13 Scopus citations
2 Scopus citations
2012

Regulation of inducible heme oxygenase and cyclooxygenase isozymes in a mouse model of spotted fever group rickettsiosis

Rydkina, E., Turpin, L. C., Sahni, A. & Sahni, S. K., Jul 2012, In : Microbial Pathogenesis. 53, 1, p. 28-36 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

UAP56 is a novel interacting partner of Bcr in regulating vascular smooth muscle cell DNA synthesis

Sahni, A., Wang, N. & Alexis, J. D., Apr 13 2012, In : Biochemical and Biophysical Research Communications. 420, 3, p. 511-515 5 p.

Research output: Contribution to journalArticle

3 Scopus citations
2011
14 Scopus citations
2010

UAP56 is an important regulator of protein synthesis and growth in cardiomyocytes

Sahni, A., Wang, N. & Alexis, J. D., Feb 26 2010, In : Biochemical and Biophysical Research Communications. 393, 1, p. 106-110 5 p.

Research output: Contribution to journalArticle

23 Scopus citations
2009

Bcr kinase activation by angiotensin II inhibits peroxisome proliferator-activated receptor γ transcriptional activity in vascular smooth muscle cells

Alexis, J. D., Wang, N., Che, W., Lerner-Marmarosh, N., Sahni, A., Korshunov, V. A., Zou, Y., Ding, B., Yan, C., Berk, B. C. & Abe, J. I., Jan 2 2009, In : Circulation Research. 104, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Selective activation of signal transducer and activator of transcription (STAT) proteins STAT1 and STAT3 in human endothelial cells infected with Rickettsia rickettsii

Sahni, S. K., Kiriakidi, S., Colonne, M. P., Sahni, A. & Silverman, D. J., Jan 1 2009, In : Clinical Microbiology and Infection. 15, SUPPL. 2, p. 303-304 2 p.

Research output: Contribution to journalArticle

8 Scopus citations
35 Scopus citations
2008

Fibrinogen synthesized by cancer cells augments the proliferative effect of fibroblast growth factor-2 (FGF-2)

Sahni, A., Simpson-haidaris, P. J., Sahni, S. K., Vaday, G. G. & Francis, C. W., Jan 2008, In : Journal of Thrombosis and Haemostasis. 6, 1, p. 176-183 8 p.

Research output: Contribution to journalArticle

125 Scopus citations
2007

Comparative analysis of host-cell signalling mechanisms activated in response to infection with Rickettsia conorii and Rickettsia typhi

Rydkina, E., Sahni, A., Silverman, D. J. & Sahni, S. K., Jul 2007, In : Journal of Medical Microbiology. 56, 7, p. 896-906 11 p.

Research output: Contribution to journalArticle

20 Scopus citations
2006

FGF-2 binding to fibrin(ogen) is required for augmented angiogenesis

Sahni, A., Khorana, A. A., Baggs, R. B., Peng, H. & Francis, C. W., Jan 1 2006, In : Blood. 107, 1, p. 126-131 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Infection of human endothelial cells with spotted fever group rickettsiae stimulates cyclooxygenase 2 expression and release of vasoactive prostaglandins

Rydkina, E., Sahni, A., Baggs, R. B., Silverman, D. J. & Sahni, S. K., Sep 2006, In : Infection and immunity. 74, 9, p. 5067-5074 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2005

Endothelial cell activation by IL-1β in the presence of fibrinogen requires αvβ3

Sahni, A., Sahni, S. K. & Francis, C. W., Oct 2005, In : Arteriosclerosis, thrombosis, and vascular biology. 25, 10, p. 2222-2227 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Potential roles for regulatory oxygenases in rickettsial pathogenesis.

Sahni, S. K., Rydkina, E., Sahni, A., Joshi, S. G. & Silverman, D. J., Dec 2005, In : Annals of the New York Academy of Sciences. 1063, p. 207-214 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2004

Fibrinogen binding potentiates FGF-2 but not VEGF induced expression of u-Pa, u-PAR, and PAI-1 in endothelial cells

Sahni, A., Sahni, S. K., Simpson-Haidaris, P. J. & Francis, C. W., Sep 1 2004, In : Journal of Thrombosis and Haemostasis. 2, 9, p. 1629-1636 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Fibrinogen regulates the expression of inflammatory chemokines through NF-κB activation of endothelial cells

Guo, M., Sahni, S. K., Sahni, A. & Francis, C. W., Oct 2004, In : Thrombosis and Haemostasis. 92, 4, p. 858-866 9 p.

Research output: Contribution to journalArticle

27 Scopus citations

Identification of a binding site on human FGF-2 for fibrinogen

Peng, H., Sahni, A., Fay, P., Bellum, S., Prudovsky, I., Maciag, T. & Francis, C. W., Mar 15 2004, In : Blood. 103, 6, p. 2114-2120 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Interleukin-1β but not IL-1α binds to fibrinogen and fibrin and has enhanced activity in the bound form

Sahni, A., Guo, M., Sahni, S. K. & Francis, C. W., Jul 15 2004, In : Blood. 104, 2, p. 409-414 6 p.

Research output: Contribution to journalArticle

45 Scopus citations

Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires αvβ3

Sahni, A. & Francis, C. W., Dec 1 2004, In : Blood. 104, 12, p. 3635-3641 7 p.

Research output: Contribution to journalArticle

61 Scopus citations
2003

FGF-2 but not FGF-1 binds fibrin and supports prolonged endothelial cell growth

Sahni, A., Altland, O. D. & Francis, C. W., Jun 2003, In : Journal of Thrombosis and Haemostasis. 1, 6, p. 1304-1310 7 p.

Research output: Contribution to journalArticle

44 Scopus citations

Heparin Inhibition of Endothelial Cell Proliferation and Organization is Dependent on Molecular Weight

Khorana, A. A., Sahni, A., Altland, O. D. & Francis, C. W., Nov 2003, In : Arteriosclerosis, thrombosis, and vascular biology. 23, 11, p. 2110-2115 6 p.

Research output: Contribution to journalArticle

118 Scopus citations

Plasmic degradation modulates activity of fibrinogen-bound fibroblast growth factor-2

Sahni, A. & Francis, C. W., Jun 2003, In : Journal of Thrombosis and Haemostasis. 1, 6, p. 1271-1277 7 p.

Research output: Contribution to journalArticle

17 Scopus citations
2002

Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expression

Rydkina, E., Sahni, A., Silverman, D. J. & Sahni, S. K., 2002, In : Infection and immunity. 70, 8, p. 4045-4052 8 p.

Research output: Contribution to journalArticle

32 Scopus citations
2000

Fffirin(ogen)-bound vascular endothelial growth factor stimulates endothelial cell proliferation

Sahni, A. & Francis, C. W., Dec 1 2000, In : Blood. 96, 11 PART II, p. 60b-61b

Research output: Contribution to journalArticle

Fibrinogen and fibrin protect fibroblast growth factor-2 from proteolytic degradation

Sahni, A., Baker, C. A., Sporn, L. A. & Francis, C. W., 2000, In : Thrombosis and Haemostasis. 83, 5, p. 736-741 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Vascular endothelial growth factor binds to fibrinogen and fibrin and stimulates endothelial cell proliferation

Sahni, A. & Francis, C. W., Dec 1 2000, In : Blood. 96, 12, p. 3772-3778 7 p.

Research output: Contribution to journalArticle

311 Scopus citations
1999

Potentiation of endothelial cell proliferation by fibrin(ogen)-bound fibroblast growth factor-2

Sahni, A., Sporn, L. A. & Francis, C. W., May 21 1999, In : Journal of Biological Chemistry. 274, 21, p. 14936-14941 6 p.

Research output: Contribution to journalArticle

79 Scopus citations
1998

Binding of basic fibroblast growth factor to fibrinogen and fibrin*

Sahni, A., Odrljin, T. & Francis, C. W., Mar 27 1998, In : Journal of Biological Chemistry. 273, 13, p. 7554-7559 6 p.

Research output: Contribution to journalArticle

196 Scopus citations