• 10819 Citations
  • 56 h-Index
1979 …2020
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1979 2019

2019
9 Citations (Scopus)

Deliberations of the Strategic Advisory Group of Experts on Immunization on the use of CYD-TDV dengue vaccine

Wilder-Smith, A., Hombach, J., Ferguson, N., Selgelid, M., O'Brien, K., Vannice, K., Barrett, A., Ferdinand, E., Flasche, S., Guzman, M., Novaes, H. M., Ng, L. C., Smith, P. G., Tharmaphornpilas, P., Yoon, I. K., Cravioto, A., Farrar, J. & Nolan, T. M., Jan 1 2019, In : The Lancet Infectious Diseases. 19, 1, p. e31-e38

Research output: Contribution to journalReview article

Dengue Vaccines
Immunization
Vaccination
Vaccines
Dengue
2018

Analysis By Deep Sequencing of Discontinued Neurotropic Yellow Fever Vaccine Strains

Beck, A. S., Wood, T., Widen, S., Thompson, J. K. & Barrett, A., Dec 1 2018, In : Scientific Reports. 8, 1, 13408.

Research output: Contribution to journalArticle

Yellow Fever Vaccine
High-Throughput Nucleotide Sequencing
Vaccines
Viruses
Yellow fever virus
9 Citations (Scopus)

Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development review-article

Hallam, H. J., Hallam, S., Rodriguez, S. E., Barrett, A., Beasley, D., Chua, A., Ksiazek, T., Milligan, G., Sathiyamoorthy, V. & Reece, L. M., Dec 1 2018, In : npj Vaccines. 3, 1, 11.

Research output: Contribution to journalArticle

Lassa Fever
Lassa virus
Virology
Epidemiology
Vaccines
4 Citations (Scopus)

Characterization of a murine model of non-lethal, symptomatic dengue virus infection

Sarathy, V., White, M., Li, L., Kaiser, J. A., Campbell, G., Milligan, G., Bourne, N. & Barrett, A., Dec 1 2018, In : Scientific Reports. 8, 1, 4900.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
Infection
Dengue
Severe Dengue
9 Citations (Scopus)

Clinical development and regulatory points for consideration for second-generation live attenuated dengue vaccines

Vannice, K. S., Wilder-Smith, A., Barrett, A., Carrijo, K., Cavaleri, M., de Silva, A., Durbin, A. P., Endy, T., Harris, E., Innis, B. L., Katzelnick, L. C., Smith, P. G., Sun, W., Thomas, S. J. & Hombach, J., Jan 1 2018, (Accepted/In press) In : Vaccine.

Research output: Contribution to journalArticle

Dengue Vaccines
Attenuated Vaccines
dengue
vaccines
Vaccines
2 Citations (Scopus)

Current status of Severe Fever with Thrombocytopenia Syndrome vaccine development

Reece, L. M., Beasley, D., Milligan, G., Sarathy, V. & Barrett, A., Apr 1 2018, In : Current Opinion in Virology. 29, p. 72-78 7 p.

Research output: Contribution to journalReview article

Thrombocytopenia
Fever
Vaccines
Viruses
Phlebovirus
7 Citations (Scopus)
Neutralizing Antibodies
Vaccines
Flavivirus
Japanese Encephalitis Vaccines
Clinical Trials

Developing Zika vaccines: The lessons for disease X

Barrett, A., Jun 26 2018, In : Genome Medicine. 10, 1, 47.

Research output: Contribution to journalComment/debate

Vaccines
Aptitude
Dengue Virus
Nucleosides
Adenosine
Dengue Vaccines
Interferon Receptors

Structural and Nonstructural Genes Contribute to the Genetic Diversity of RNA Viruses

Collins, N. D., Beck, A. S., Widen, S., Wood, T., Higgs, S. & Barrett, A., Oct 30 2018, In : mBio. 9, 5

Research output: Contribution to journalArticle

RNA Viruses
RNA Replicase
Viruses
Genes
Yellow fever virus
3 Citations (Scopus)

Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy

Gerson, J. E., Farmer, K. M., Henson, N., Castillo-Carranza, D. L., Carretero Murillo, M., Sengupta, U., Barrett, A. & Kayed, R., Mar 15 2018, In : Molecular Neurodegeneration. 13, 1, 13.

Research output: Contribution to journalArticle

Synucleins
Immunotherapy
Poisons
Monoclonal Antibodies
Lewy Bodies

Terrestrial Bird Migration and West Nile Virus Circulation, United States

Swetnam, D., Widen, S., Wood, T., Reyna, M., Wilkerson, L., Debboun, M., Symonds, D. A., Mead, D. G., Beaty, B. J., Guzman, H., Tesh, R. B. & Barrett, A., Dec 1 2018, In : Emerging Infectious Diseases. 24, 12, p. 2184-2194 11 p.

Research output: Contribution to journalArticle

West Nile virus
Birds
Zoonoses
Communicable Diseases
2 Citations (Scopus)

The reemergence of yellow fever

Barrett, A., Aug 31 2018, In : Science. 361, 6405, p. 847-848 2 p.

Research output: Contribution to journalArticle

yellow fever
Yellow Fever

West Nile in Europe: an increasing public health problem

Barrett, A., Jan 1 2018, In : Journal of Travel Medicine. 25, 1

Research output: Contribution to journalArticle

Public Health
9 Citations (Scopus)

Zika, dengue and yellow fever viruses induce differential anti-viral immune responses in human monocytic and first trimester trophoblast cells

Luo, H., Winkelmann, E. R., Fernandez-Salas, I., Li, L., Mayer, S. V., Danis-Lozano, R., Sanchez-Casas, R. M., Vasilakis, N., Tesh, R., Barrett, A., Weaver, S. & Wang, T., Mar 1 2018, In : Antiviral Research. 151, p. 55-62 8 p.

Research output: Contribution to journalArticle

Yellow fever virus
Dengue
Trophoblasts
First Pregnancy Trimester
Dengue Virus
2017
2 Citations (Scopus)

Active evolution of memory B-cells specific to viral gH/gL/ pUL128/130/131 pentameric complex in healthy subjects with silent human cytomegalovirus infection

Xia, L., Tang, A., Meng, W., Freed, D. C., He, L., Wang, D., Li, F., Li, L., Xiong, W., Gui, X., Schultz, R. D., Chen, H., He, X., Swoyer, R., Ha, S., Liu, Y., Morris, C. D., Zhou, Y., Wang, I. M., Zhao, Q. & 10 othersLuo, W., Xia, N., Espeseth, A. S., Hazuda, D. J., Rupp, R., Barrett, A., Zhang, N., Zhu, J., Fu, T. M. & An, Z., 2017, In : Oncotarget. 8, 43, p. 73654-73669 16 p.

Research output: Contribution to journalArticle

Cytomegalovirus Infections
Healthy Volunteers
B-Lymphocytes
Infection
Vaccines

A DENV-2-type-specific monoclonal antibody binds to the denv-complex-reactive antigenic site on envelope protein domain 3

Sarathy, V., Pitcher, T. J., Gromowski, G. D., Roehrig, J. T. & Barrett, A., Jun 1 2017, In : Journal of General Virology. 98, 6, p. 1299-1304 6 p., 000785.

Research output: Contribution to journalArticle

Dengue Virus
Catalytic Domain
Monoclonal Antibodies
Viral Envelope Proteins
Viral Structures
3 Citations (Scopus)

A lethal model of disseminated dengue virus type 1 infection in AG129 mice

Milligan, G., Sarathy, V., White, M. M., Greenberg, M. B., Campbell, G., Pyles, R., Barrett, A. & Bourne, N., Oct 1 2017, In : Journal of General Virology. 98, 10, p. 2507-2519 13 p., 000923.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
Dengue
Antibody-Dependent Enhancement
Vaccines
96 Citations (Scopus)

A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models

Shan, C., Muruato, A. E., Nunes, B. T. D., Luo, H., Xie, X., Medeiros, D. B. A., Wakamiya, M., Tesh, R. B., Barrett, A., Wang, T., Weaver, S., Vasconcelos, P. F. C., Rossi, S. & Shi, P-Y., Apr 10 2017, (Accepted/In press) In : Nature Medicine.

Research output: Contribution to journalArticle

Viruses
Immunity
Vaccines
Interferon Type I
Viremia
41 Citations (Scopus)

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

Shan, C., Muruato, A. E., Jagger, B. W., Richner, J., Nunes, B. T. D., Medeiros, D. B. A., Xie, X., Nunes, J. G. C., Morabito, K. M., Kong, W. P., Pierson, T. C., Barrett, A., Weaver, S., Rossi, S., Vasconcelos, P. F. C., Graham, B. S., Diamond, M. S. & Shi, P-Y., Dec 1 2017, In : Nature Communications. 8, 1, 676.

Research output: Contribution to journalArticle

vaccines
testes
Attenuated Vaccines
pregnancy
viruses
5 Citations (Scopus)

Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014

Cajimat, M. N. B., Rodriguez, S. E., Schuster, I. U. E., Swetnam, D. M., Ksiazek, T., Habela, M. A., Negredo, A. I., Estrada-Peña, A., Barrett, A. & Bente, D., Oct 1 2017, In : Vector-Borne and Zoonotic Diseases. 17, 10, p. 714-719 6 p.

Research output: Contribution to journalArticle

Crimean-Congo hemorrhagic fever virus
Ticks
Spain
Crimean Hemorrhagic Fever
Viruses
15 Citations (Scopus)

Live Attenuated Yellow Fever 17D Vaccine: A Legacy Vaccine Still Controlling Outbreaks In Modern Day

Collins, N. D. & Barrett, A., Mar 1 2017, In : Current Infectious Disease Reports. 19, 3, 14.

Research output: Contribution to journalReview article

Yellow Fever Vaccine
Attenuated Vaccines
Disease Outbreaks
Vaccines
Immunity
1 Citation (Scopus)

MAVS is essential for primary CD4+ T cell immunity but not for recall T cell responses following an attenuated West Nile virus infection

Luo, H., Winkelmann, E., Xie, G., Fang, R., Peng, B., Li, L., Lazear, H. M., Paessler, S., Diamond, M. S., Gale, M., Barrett, A. & Wang, T., 2017, In : Journal of Virology. 91, 6, e02097-16.

Research output: Contribution to journalArticle

West Nile virus
Virus Diseases
Antiviral Agents
Immunity
T-lymphocytes
4 Citations (Scopus)

p38MAPK plays a critical role in induction of a pro-inflammatory phenotype of retinal Müller cells following Zika virus infection

Zhu, S., Luo, H., Liu, H., Ha, Y., Mays, E. R., Lawrence, R. E., Winkelmann, E., Barrett, A., Smith, S. B., Wang, M., Wang, T. & Zhang, W., Sep 1 2017, In : Antiviral Research. 145, p. 70-81 12 p.

Research output: Contribution to journalArticle

Phenotype
Intercellular Signaling Peptides and Proteins
Posterior Uveitis
Eye Abnormalities
Pathology
73 Citations (Scopus)

Vaccine Mediated Protection Against Zika Virus-Induced Congenital Disease

Richner, J. M., Jagger, B. W., Shan, C., Fontes, C. R., Dowd, K. A., Cao, B., Himansu, S., Caine, E. A., Nunes, B. T. D., Medeiros, D. B. A., Muruato, A. E., Foreman, B. M., Luo, H., Wang, T., Barrett, A., Weaver, S., Vasconcelos, P. F. C., Rossi, S., Ciaramella, G., Mysorekar, I. U. & 3 othersPierson, T. C., Shi, P-Y. & Diamond, M. S., Jul 13 2017, In : Cell. 170, 2, p. 273-283.e12

Research output: Contribution to journalArticle

Viruses
Vaccines
Fetus
Viral Vaccines
Glycosylation
2 Citations (Scopus)

Virulence determinants of West Nile virus: How can these be used for vaccine design?

Kaiser, J. A., Wang, T. & Barrett, A., May 1 2017, In : Future Virology. 12, 5, p. 283-295 13 p.

Research output: Contribution to journalReview article

West Nile Virus Vaccines
West Nile virus
Virulence
Vaccines
Culicidae
11 Citations (Scopus)
Yellow fever virus
Yellow Fever
Attenuated Vaccines
live vaccines
Vaccines
2016
1 Citation (Scopus)

A humanized monoclonal antibody neutralizes yellow fever virus strain 17D-204 inA vitro but does not protect a mouse model from disease

Calvert, A. E., Dixon, K. L., Piper, J., Bennett, S. L., Thibodeaux, B. A., Barrett, A., Roehrig, J. T. & Blair, C. D., Jul 1 2016, In : Antiviral Research. 131, p. 92-99 8 p.

Research output: Contribution to journalArticle

Yellow fever virus
Antibodies, Monoclonal, Humanized
Monoclonal Antibodies
Vaccination
Yellow Fever Vaccine
102 Citations (Scopus)

An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors

Shan, C., Xie, X., Muruato, A. E., Rossi, S., Roundy, C. M., Azar, S. R., Yang, Y., Tesh, R. B., Bourne, N., Barrett, A., Vasilakis, N., Weaver, S. & Shi, P-Y., Apr 14 2016, (Accepted/In press) In : Cell Host and Microbe.

Research output: Contribution to journalArticle

Culicidae
Antiviral Agents
Virulence
Complementary DNA
Clone Cells
7 Citations (Scopus)

Differential Infectivities among Different Japanese Encephalitis Virus Genotypes in Culex quinquefasciatus Mosquitoes

Huang, Y. J. S., Hettenbach, S. M., Park, S. L., Higgs, S., Barrett, A., Hsu, W. W., Harbin, J. N., Cohnstaedt, L. W. & Vanlandingham, D. L., Oct 5 2016, In : PLoS Neglected Tropical Diseases. 10, 10, e0005038.

Research output: Contribution to journalArticle

Japanese Encephalitis Virus
Culex
Culicidae
Genotype
Arthropod Vectors
11 Citations (Scopus)

Dysregulation of toll-like receptor 7 compromises innate and adaptive T cell responses and host resistance to an attenuated West Nile virus infection in old mice

Xie, G., Luo, H., Pang, L., Peng, B., Winkelmann, E., McGruder, B., Hesse, J., Whiteman, M., Campbell, G., Milligan, G., Cong, Y., Barrett, A. & Wang, T., 2016, In : Journal of Virology. 90, 3, p. 1333-1344 12 p.

Research output: Contribution to journalArticle

Toll-Like Receptor 7
West Nile virus
Virus Diseases
T-lymphocytes
T-Lymphocytes
30 Citations (Scopus)

Fast-track zika vaccine development-is it possible?

Thomas, S. J., L'Azou, M., Barrett, A. & Jackson, N. A. C., Sep 29 2016, In : New England Journal of Medicine. 375, 13, p. 1212-1216 5 p.

Research output: Contribution to journalReview article

Infectious Pregnancy Complications
Viral Vaccines
Drug Approval
Vaccines
Pregnancy
13 Citations (Scopus)

Research and development of Zika virus vaccines

Dawes, B. E., Smalley, C. A., Tiner, B. L., Beasley, D., Milligan, G., Reece, L. M., Hombach, J. & Barrett, A., Jul 28 2016, In : npj Vaccines. 1, 16007.

Research output: Contribution to journalReview article

Vaccines
Flavivirus
Research
Flaviviridae
Microcephaly
11 Citations (Scopus)

Transstadial Transmission and Long-term Association of Crimean-Congo Hemorrhagic Fever Virus in Ticks Shapes Genome Plasticity

Xia, H., Beck, A. S., Gargili, A., Forrester, N., Barrett, A. & Bente, D., Oct 24 2016, In : Scientific Reports. 6, 35819.

Research output: Contribution to journalArticle

Crimean-Congo hemorrhagic fever virus
Ticks
Arboviruses
Genome
Vertebrates
2 Citations (Scopus)

Vaccinology in the twenty-first century

Barrett, A., Jan 1 2016, In : npj Vaccines. 1, 16009.

Research output: Contribution to journalReview article

36 Citations (Scopus)

Yellow fever in Angola and beyond \- The problem of vaccine supply and demand

Barrett, A., Jul 28 2016, In : New England Journal of Medicine. 375, 4, p. 301-303 3 p.

Research output: Contribution to journalReview article

Yellow Fever Vaccine
Angola
Yellow fever virus
Yellow Fever
Immunization Programs
9 Citations (Scopus)

Zika vaccine candidates progress through nonclinical development and enter clinical trials

Barrett, A., Nov 10 2016, In : npj Vaccines. 1, 16023.

Research output: Contribution to journalReview article

Vaccines
Clinical Trials
47 Citations (Scopus)

Zika Virus: Diagnosis, Therapeutics, and Vaccine

Shan, C., Xie, X., Barrett, A., Garcia-Blanco, M., Tesh, R. B., Vasconcelos, P. F. D. C., Vasilakis, N., Weaver, S. & Shi, P-Y., Mar 11 2016, In : ACS Infectious Diseases. 2, 3, p. 170-172 3 p.

Research output: Contribution to journalArticle

Vaccines
Central America
South America
Emergencies
Public Health
2015
25 Citations (Scopus)

A dengue virus type 4 model of disseminated lethal infection in AG129 mice

Milligan, G., Sarathy, V., Infante, E., Li, L., Campbell, G., Beatty, P. R., Harris, E., Barrett, A. & Bourne, N., May 4 2015, In : PLoS One. 10, 5, e0125476.

Research output: Contribution to journalArticle

Dengue virus
Dengue Virus
Viruses
dengue
Dengue
32 Citations (Scopus)
Interferon alpha-beta Receptor
Dengue virus
Dengue Virus
interferons
Dengue
West Nile virus
glycosylation
Glycosylation
Endoplasmic Reticulum
endoplasmic reticulum
West Nile virus
glycosylation
Glycosylation
Endoplasmic Reticulum
endoplasmic reticulum
5 Citations (Scopus)
West Nile virus
glycosylation
Glycosylation
Endoplasmic Reticulum
endoplasmic reticulum
4 Citations (Scopus)

A West Nile virus NS4B-P38G mutant strain induces cell intrinsic innate cytokine responses in human monocytic and macrophage cells

Xie, G., Luo, H., Tian, B., Mann, B., Bao, X., McBride, J., Tesh, R., Barrett, A. & Wang, T., Feb 11 2015, In : Vaccine. 33, 7, p. 869-878 10 p.

Research output: Contribution to journalArticle

West Nile virus
macrophages
cytokines
Macrophages
Cytokines
10 Citations (Scopus)
Dengue Virus
Dengue
Infection
Antiviral Agents
Vaccines
17 Citations (Scopus)

Current status and future prospects of yellow fever vaccines

Beck, A. S. & Barrett, A., Nov 2 2015, In : Expert Review of Vaccines. 14, 11, p. 1479-1492 14 p.

Research output: Contribution to journalArticle

Yellow Fever Vaccine
Synthetic Vaccines
Vaccines
Japanese Encephalitis Vaccines
Attenuated Vaccines
20 Citations (Scopus)

Defining new therapeutics using a more immunocompetent mouse model of antibody-enhanced dengue virus infection

Pinto, A. K., Brien, J. D., Lam, C. Y. K., Johnson, S., Chiang, C., Hiscott, J., Sarathy, V., Barrett, A., Shresta, S. & Diamond, M. S., 2015, In : mBio. 6, 5, e01316-15.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
Antibodies
Antibody-Dependent Enhancement
Severe Dengue
7 Citations (Scopus)

Functional analysis of dengue virus (DENV) type 2 envelope protein domain 3 type-specific and DENV complex-reactive critical epitope residues

Pitcher, T. J., Sarathy, V., Matsui, K., Gromowski, G. D., Huang, C. Y. H. & Barrett, A., Feb 1 2015, In : Journal of General Virology. 96, 2, p. 288-293 6 p.

Research output: Contribution to journalArticle

Viral Envelope Proteins
Dengue Virus
Epitopes
Viruses
Protein Domains

Introduction

Coller, B. A., Barrett, A. & Thomas, S. J., Dec 10 2015, In : Vaccine. 33, 50, p. 7049-7050 2 p.

Research output: Contribution to journalArticle

Dengue Vaccines
Preclinical Drug Evaluations
dengue
Dengue
Drug Discovery
20 Citations (Scopus)

Mouse models of dengue virus infection for vaccine testing

Sarathy, V., Milligan, G., Bourne, N. & Barrett, A., Dec 10 2015, In : Vaccine. 33, 50, p. 7051-7060 10 p.

Research output: Contribution to journalArticle

Dengue virus
Dengue Virus
Virus Diseases
dengue
Vaccines