• 8350 Citations
  • 37 h-Index
1988 …2020

Research output per year

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Research Output

2020

Nucleolin mediates the binding of cancer cells to L-selectin under conditions of lymphodynamic shear stress

Goldson, T. M., Turner, K. L., Huang, Y., Carlson, G. E., Caggiano, E. G., Oberhauser, A. F., Fennewald, S. M., Burdick, M. M. & Resto, V. A., Jan 1 2020, In : American Journal of Physiology - Cell Physiology. 318, 1, p. C83-C93

Research output: Contribution to journalArticle

1 Scopus citations
2019

Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies

Chen, Z., Gu, J., El Ayadi, A., Oberhauser, A., Zhou, J., Sousse, L., Finnerty, C., Herndon, D. & Boor, P. J., Jan 1 2019, In : Toxicology and Applied Pharmacology. 362, p. 9-19 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mechanical unfolding of spectrin reveals a super-exponential dependence of unfolding rate on force

Renn, J. P., Bhattacharyya, S., Bai, H., He, C., Li, H., Oberhauser, A. F., Marko, J. F., Makarov, D. E. & Matouschek, A., Jul 31 2019, In : Scientific reports. 9, 1, 1 p., 11101.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2018

The central domain of UNC-45 chaperone inhibits the myosin power stroke

Bujalowski, P., Nicholls, P., Garza, E. & Oberhauser, A., Jan 1 2018, In : FEBS Open Bio. 8, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

2015

N-(2-aminoethyl) ethanolamine-induced morphological, biochemical, and biophysical alterations in vascular matrix associated with dissecting aortic aneurysm

Chen, Z., Xu, Y., Bujalowski, P., Oberhauser, A. & Boor, P. J., Dec 1 2015, In : Toxicological Sciences. 148, 2, p. 421-432 12 p., kfv194.

Research output: Contribution to journalArticle

4 Scopus citations

Thermally-induced structural changes in an armadillo repeat protein suggest a novel thermosensor mechanism in a molecular chaperone

Bujalowski, P. J., Nicholls, P., Barral, J. M. & Oberhauser, A. F., Feb 2 2015, In : FEBS Letters. 589, 1, p. 123-130 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke

Nicholls, P., Bujalowski, P. J., Epstein, H. F., Boehning, D. F., Barral, J. M. & Oberhauser, A. F., Nov 3 2014, In : FEBS Letters. 588, 21, p. 3977-3981 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

UNC-45B chaperone: The role of its domains in the interaction with the myosin motor domain

Bujalowski, P. J., Nicholls, P. & Oberhauser, A. F., Aug 5 2014, In : Biophysical Journal. 107, 3, p. 654-661 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Analysis of the REJ module of polycystin-1 using molecular modeling and force-spectroscopy techniques

Xu, M., Ma, L., Bujalowski, P. J., Qian, F., Sutton, R. B. & Oberhauser, A. F., 2013, In : Journal of Biophysics. 525231.

Research output: Contribution to journalArticle

3 Scopus citations

Bax phosphorylation association with nucleus and oligomerization after neonatal Hypoxia-ischemia

Infante, S. K., Oberhauser, A. F. & Perez-Polo, J. R., Sep 1 2013, In : Journal of Neuroscience Research. 91, 9, p. 1152-1164 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Preface

Oberhauser, A., Jan 1 2013, Single-molecule Studies of Proteins. Springer New York, p. v-vii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

1 Scopus citations

Single-molecule methods

Bujalowski, P., Sherman, M. & Oberhauser, A., Jan 1 2013, Molecular Biophysics for the Life Sciences. Springer New York, p. 257-288 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Single-molecule studies of proteins

Oberhauser, A. F., Jan 1 2013, Springer New York. 274 p.

Research output: Book/ReportBook

6 Scopus citations

Tracking unfolding and refolding reactions of single proteins using atomic force microscopy methods

Bujalowski, P. J. & Oberhauser, A. F., Apr 1 2013, In : Methods. 60, 2, p. 151-160 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
2012

Engineering proteins with enhanced mechanical stability by force-specific sequence motifs

Lu, W., Negi, S. S., Oberhauser, A. F. & Braun, W., May 1 2012, In : Proteins: Structure, Function and Bioinformatics. 80, 5, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Purification and aggregation of the amyloid precursor protein intracellular domain

El Ayadi, A., Stieren, E. S., Barral, J. M., Oberhauser, A. F. & Boehning, D., Aug 28 2012, In : Journal of Visualized Experiments. 66

Research output: Contribution to journalArticle

12 Scopus citations

Single-molecule force spectroscopy of polycystic kidney disease proteins

Ma, L., Xu, M. & Oberhauser, A. F., Jan 1 2012, Spectroscopic Methods of Analysis: Methods and Protocols. Humana Press Inc., p. 297-310 14 p. (Methods in Molecular Biology; vol. 875).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Tracking UNC-45 chaperone-myosin interaction with a titin mechanical reporter

Kaiser, C. M., Bujalowski, P. J., Ma, L., Anderson, J., Epstein, H. F. & Oberhauser, A. F., May 2 2012, In : Biophysical Journal. 102, 9, p. 2212-2219 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011

Shape of tropoelastin, the highly extensible protein that controls human tissue elasticity

Baldock, C., Oberhauser, A. F., Ma, L., Lammie, D., Siegler, V., Mithieux, S. M., Tu, Y., Chow, J. Y. H., Suleman, F., Malfois, M., Rogers, S., Guo, L., Irving, T. C., Wess, T. J. & Weiss, A. S., Mar 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 11, p. 4322-4327 6 p.

Research output: Contribution to journalArticle

114 Scopus citations

Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein

Stieren, E. S., El Ayadi, A., Xiao, Y., Siller, E., Landsverk, M. L., Oberhauser, A. F., Barral, J. M. & Boehning, D., Oct 14 2011, In : Journal of Biological Chemistry. 286, 41, p. 35689-35698 10 p.

Research output: Contribution to journalArticle

61 Scopus citations
2010

Nanoscale analysis of the effect of pathogenic mutations on polycystin-1

Ma, L., Xu, M. & Oberhauser, A. F., Aug 4 2010, Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. p. 365-366 2 p. (Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Naturally occurring osmolytes modulate the nanomechanical properties of polycystic kidney disease domains

Ma, L., Xu, M. & Oberhauser, A. F., Dec 3 2010, In : Journal of Biological Chemistry. 285, 49, p. 38438-38443 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

Holst, J., Watson, S., Lord, M. S., Eamegdool, S. S., Bax, D. V., Nivison-Smith, L. B., Kondyurin, A., Ma, L., Oberhauser, A. F., Weiss, A. S. & Rasko, J. E. J., Oct 1 2010, In : Nature Biotechnology. 28, 10, p. 1123-1128 6 p.

Research output: Contribution to journalArticle

182 Scopus citations

Understanding biology by stretching proteins: recent progress

Galera-Prat, A., Gómez-Sicilia, A., Oberhauser, A. F., Cieplak, M. & Carrión-Vázquez, M., Feb 1 2010, In : Current Opinion in Structural Biology. 20, 1, p. 63-69 7 p.

Research output: Contribution to journalReview article

52 Scopus citations
2009

A LIM-9 (FHL) / SCPL-1 (SCP) Complex Interacts with the C-terminal Protein Kinase Regions of UNC-89 (Obscurin) in Caenorhabditis elegans Muscle

Xiong, G., Qadota, H., Mercer, K. B., McGaha, L. A., Oberhauser, A. F. & Benian, G. M., Mar 6 2009, In : Journal of Molecular Biology. 386, 4, p. 976-988 13 p.

Research output: Contribution to journalArticle

25 Scopus citations
17 Scopus citations

Naturally occurring mutations alter the stability of polycystin-1 polycystic kidney disease (PKD) domains

Ma, L., Xu, M., Forman, J. R., Clarke, J. & Oberhauser, A. F., Nov 20 2009, In : Journal of Biological Chemistry. 284, 47, p. 32942-32949 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

The C2 domains of human synaptotagmin 1 have distinct mechanical properties

Fuson, K. L., Liang, M., Sutton, R. B. & Oberhauser, A. F., Feb 4 2009, In : Biophysical Journal. 96, 3, p. 1083-1090 8 p.

Research output: Contribution to journalArticle

18 Scopus citations
2008

Mechanical biochemistry of proteins one molecule at a time

Oberhauser, A. F. & Carrión-Vázquez, M., Mar 14 2008, In : Journal of Biological Chemistry. 283, 11, p. 6617-6621 5 p.

Research output: Contribution to journalShort survey

74 Scopus citations
2006

The mechanical properties of E. coli type 1 pili measured by atomic force microscopy techniques

Miller, E., Garcia, T., Hultgren, S. & Oberhauser, A. F., Nov 2006, In : Biophysical journal. 91, 10, p. 3848-3856 9 p.

Research output: Contribution to journalArticle

103 Scopus citations

The molecular elasticity of the insect flight muscle proteins projectin and kettin

Bullard, B., Garcia, T., Benes, V., Leake, M. C., Linke, W. A. & Oberhauser, A. F., Mar 21 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 12, p. 4451-4456 6 p.

Research output: Contribution to journalArticle

73 Scopus citations
2005

The nanomechanics of polycystin-1 extracellular region

Qian, F., Wei, W., Germino, G. & Oberhauser, A., Dec 9 2005, In : Journal of Biological Chemistry. 280, 49, p. 40723-40730 8 p.

Research output: Contribution to journalArticle

59 Scopus citations
2003

The force-driven conformations of heparin studied with single molecule force microscopy

Marszalek, P. E., Oberhauser, A. F., Li, H. & Fernandez, J. M., Oct 1 2003, In : Biophysical Journal. 85, 4, p. 2696-2704 9 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations

The mechanical stability of ubiquitin is linkage dependent

Carrion-Vazquez, M., Li, H., Lu, H., Marszalek, P. E., Oberhauser, A. F. & Fernandez, J. M., Sep 1 2003, In : Nature Structural Biology. 10, 9, p. 738-743 6 p.

Research output: Contribution to journalArticle

349 Scopus citations
2002

Chair-boat transitions in single polysaccharide molecules observed with force-ramp AFM

Marszalek, P. E., Li, H., Oberhauser, A. F. & Fernandez, J. M., Apr 2 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 7, p. 4278-4283 6 p.

Research output: Contribution to journalArticle

120 Scopus citations

Reverse engineering of the giant muscle protein titin

Li, H., Linke, W. A., Oberhauser, A. F., Carrion-Vazquez, M., Kerkvliet, J. G., Lu, H., Marszalek, P. E. & Fernandez, J. M., Aug 29 2002, In : Nature. 418, 6901, p. 998-1002 5 p.

Research output: Contribution to journalArticle

379 Scopus citations

The mechanical hierarchies of fibronectin observed with single-molecule AFM

Oberhauser, A. F., Badilla-Fernandez, C., Carrion-Vazquez, M. & Fernandez, J. M., Jan 1 2002, In : Journal of Molecular Biology. 319, 2, p. 433-447 15 p.

Research output: Contribution to journalArticle

301 Scopus citations
2001

Multiple conformations of PEVK proteins detected by single-molecule techniques

Li, H., Oberhauser, A. F., Redick, S. D., Carrion-Vazquez, M., Erickson, H. P. & Fernandez, J. M., Sep 11 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 19, p. 10682-10686 5 p.

Research output: Contribution to journalArticle

139 Scopus citations

RNA structure: Putting on hair(pins)

Fernandez, J. M., Chu, S. & Oberhauser, A. F., Apr 27 2001, In : Science. 292, 5517, p. 653-654 2 p.

Research output: Contribution to journalShort survey

23 Scopus citations

Stepwise unfolding of titin under force-clamp atomic force microscopy

Oberhauser, A. F., Hansma, P. K., Carrion-Vazquez, M. & Fernandez, J. M., Jan 16 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 2, p. 468-472 5 p.

Research output: Contribution to journalArticle

Open Access
329 Scopus citations
2000

Atomic force microscopy captures quantized plastic deformation in gold nanowires

Marszalek, P. E., Greenleaf, W. J., Li, H., Oberhauser, A. F. & Fernandez, J. M., Jun 6 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 12, p. 6282-6286 5 p.

Research output: Contribution to journalArticle

104 Scopus citations

Atomic force microscopy reveals the mechanical design of a modular protein

Li, H., Oberhauser, A. F., Fowler, S. B., Clarke, J. & Fernandez, J. M., Jun 6 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 12, p. 6527-6531 5 p.

Research output: Contribution to journalArticle

237 Scopus citations

Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering

Carrion-Vazquez, M., Oberhauser, A. F., Fisher, T. E., Marszalek, P. E., Li, H. & Fernandez, J. M., Dec 1 2000, In : Progress in Biophysics and Molecular Biology. 74, 1-2, p. 63-91 29 p.

Research output: Contribution to journalReview article

343 Scopus citations

Point mutations alter the mechanical stability of immunoglobulin modules

Li, H., Carrion-Vazquez, M., Oberhauser, A. F., Marszalek, P. E. & Fernandez, J. M., Dec 23 2000, In : Nature Structural Biology. 7, 12, p. 1117-1120 4 p.

Research output: Contribution to journalArticle

171 Scopus citations

Single molecule force spectroscopy of modular proteins in the nervous system

Fisher, T. E., Carrion-Vazquez, M., Oberhauser, A. F., Li, H., Marszalek, P. E. & Fernandez, J. M., Jan 1 2000, In : Neuron. 27, 3, p. 435-446 12 p.

Research output: Contribution to journalReview article

Open Access
37 Scopus citations
1999

Atomic force microscopy captures length phenotypes in single proteins

Carrion-Vazquez, M., Marszalek, P. E., Oberhauser, A. F. & Fernandez, J. M., Sep 28 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 20, p. 11288-11292 5 p.

Research output: Contribution to journalArticle

154 Scopus citations

Atomic levers control pyranose ring conformations

Marszalek, P. E., Pang, Y. P., Li, H., El Yazal, J., Oberhauser, A. F. & Fernandez, J. M., Jul 6 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 14, p. 7894-7898 5 p.

Research output: Contribution to journalArticle

130 Scopus citations

Conformational transitions in single protein and polysaccharide molecules studied with AFM techniques

Marszalek, P. E., Oberhauser, A. F., Carrion-Vazquez, M. & Fernandez, J. M., Dec 1 1999, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. IEEE, 1 p. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Force spectroscopy of cell adhesion molecules

Oberhauser, A. F., Marszalek, P. E., Carrion-Vazquez, M. & Fernandez, J. M., Dec 1 1999, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. IEEE, 1 p. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution