• 8298 Citations
  • 37 h-Index
1988 …2022

Research output per year

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Research Output

Activation by divalent cations of a Ca2+-activated K+ channel from skeletal muscle membrane

Oberhauser, A., Alvarez, O. & Latorre, R., Jul 1 1988, In : Journal of General Physiology. 92, 1, p. 67-86 20 p.

Research output: Contribution to journalArticle

Open Access
104 Scopus citations

A fusion pore phenotype in mast cells of the ruby-eye mouse

Oberhauser, A. F. & Fernandez, J. M., Dec 10 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 25, p. 14349-14354 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

A LIM-9 (FHL) / SCPL-1 (SCP) Complex Interacts with the C-terminal Protein Kinase Regions of UNC-89 (Obscurin) in Caenorhabditis elegans Muscle

Xiong, G., Qadota, H., Mercer, K. B., McGaha, L. A., Oberhauser, A. F. & Benian, G. M., Mar 6 2009, In : Journal of Molecular Biology. 386, 4, p. 976-988 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

Analysis of the REJ module of polycystin-1 using molecular modeling and force-spectroscopy techniques

Xu, M., Ma, L., Bujalowski, P. J., Qian, F., Sutton, R. B. & Oberhauser, A. F., Jul 1 2013, In : Journal of Biophysics. 525231.

Research output: Contribution to journalArticle

3 Scopus citations

Atomic force microscopy captures length phenotypes in single proteins

Carrion-Vazquez, M., Marszalek, P. E., Oberhauser, A. F. & Fernandez, J. M., Sep 28 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 20, p. 11288-11292 5 p.

Research output: Contribution to journalArticle

151 Scopus citations

Atomic force microscopy captures quantized plastic deformation in gold nanowires

Marszalek, P. E., Greenleaf, W. J., Li, H., Oberhauser, A. F. & Fernandez, J. M., Jun 6 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 12, p. 6282-6286 5 p.

Research output: Contribution to journalArticle

104 Scopus citations

Atomic force microscopy reveals the mechanical design of a modular protein

Li, H., Oberhauser, A. F., Fowler, S. B., Clarke, J. & Fernandez, J. M., Jun 6 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 12, p. 6527-6531 5 p.

Research output: Contribution to journalArticle

236 Scopus citations

Atomic levers control pyranose ring conformations

Marszalek, P. E., Pang, Y. P., Li, H., El Yazal, J., Oberhauser, A. F. & Fernandez, J. M., Jul 6 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 14, p. 7894-7898 5 p.

Research output: Contribution to journalArticle

129 Scopus citations

Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers: Ion conduction and gating properties

Behrens, M. I., Oberhauser, A., Bezanilla, F. & Latorre, R., Jan 1 1989, In : Journal of General Physiology. 93, 1, p. 23-41 19 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

Bax phosphorylation association with nucleus and oligomerization after neonatal Hypoxia-ischemia

Infante, S. K., Oberhauser, A. F. & Perez-Polo, J. R., Sep 1 2013, In : Journal of Neuroscience Research. 91, 9, p. 1152-1164 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Chair-boat transitions in single polysaccharide molecules observed with force-ramp AFM

Marszalek, P. E., Li, H., Oberhauser, A. F. & Fernandez, J. M., Apr 2 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 7, p. 4278-4283 6 p.

Research output: Contribution to journalArticle

118 Scopus citations

Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke

Nicholls, P., Bujalowski, P. J., Epstein, H. F., Boehning, D. F., Barral, J. M. & Oberhauser, A. F., Nov 3 2014, In : FEBS Letters. 588, 21, p. 3977-3981 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Conformational transitions in single protein and polysaccharide molecules studied with AFM techniques

Marszalek, P. E., Oberhauser, A. F., Carrion-Vazquez, M. & Fernandez, J. M., Dec 1 1999, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. IEEE, 1 p. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Do caged-Ca2+ compounds mimic the physiological stimulus for secretion?

Oberhauser, A. F., Robinson, I. M. & Fernandez, J. M., 1995, In : Journal of Physiology - Paris. 89, 2, p. 71-75 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies

Chen, Z., Gu, J., El Ayadi, A., Oberhauser, A., Zhou, J., Sousse, L., Finnerty, C., Herndon, D. & Boor, P. J., Jan 1 2019, In : Toxicology and Applied Pharmacology. 362, p. 9-19 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Engineering proteins with enhanced mechanical stability by force-specific sequence motifs

Lu, W., Negi, S. S., Oberhauser, A. F. & Braun, W., May 1 2012, In : Proteins: Structure, Function and Bioinformatics. 80, 5, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
Open Access
49 Scopus citations

Exocytotic fusion is activated by Rab3a peptides

Oberhauser, A. F., Monck, J. R., Balch, W. E. & Fernandez, J. M., Jan 1 1992, In : Nature. 360, 6401, p. 270-273 4 p.

Research output: Contribution to journalArticle

140 Scopus citations

Force spectroscopy of cell adhesion molecules

Oberhauser, A. F., Marszalek, P. E., Carrion-Vazquez, M. & Fernandez, J. M., Dec 1 1999, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. IEEE, 1 p. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hydrophobic ions amplify the capacitive currents used to measure exocytotic fusion

Oberhauser, A. F. & Fernandez, J. M., Jan 1 1995, In : Biophysical Journal. 69, 2, p. 451-459 9 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Inositol (1,4,5)-trisphosphate activates a calcium channel in isolated sarcoplasmic reticulum membranes

Suárez-Isla, B. A., Irribarra, V., Oberhauser, A., Larralde, L., Bull, R., Hidalgo, C. & Jaimovich, E., Jan 1 1988, In : Biophysical Journal. 54, 4, p. 737-741 5 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Is swelling of the secretory granule matrix the force that dilates the exocytotic fusion pore?

Monck, J. R., Oberhauser, A. F., Alvarez de Toledo, G. & Fernandez, J. M., Jan 1 1991, In : Biophysical Journal. 59, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Is the Activity of the Fusion Pore Scaffold Regulated by a Coincidence Detector?

ROBINSON, IAIN. M., OBERHAUSER, ANDRES. F. & FERNANDEZ, JULIO. M., Mar 1994, In : Annals of the New York Academy of Sciences. 710, 1, p. 168-178 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mechanical and chemical unfolding of a single protein: A comparison

Carrion-Vazquez, M., Oberhauser, A. F., Fowler, S. B., Marszalek, P. E., Broedel, S. E., Clarke, J. & Fernandez, J. M., Mar 30 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 7, p. 3694-3699 6 p.

Research output: Contribution to journalArticle

820 Scopus citations

Mechanical biochemistry of proteins one molecule at a time

Oberhauser, A. F. & Carrión-Vázquez, M., Mar 14 2008, In : Journal of Biological Chemistry. 283, 11, p. 6617-6621 5 p.

Research output: Contribution to journalShort survey

74 Scopus citations

Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering

Carrion-Vazquez, M., Oberhauser, A. F., Fisher, T. E., Marszalek, P. E., Li, H. & Fernandez, J. M., Dec 1 2000, In : Progress in Biophysics and Molecular Biology. 74, 1-2, p. 63-91 29 p.

Research output: Contribution to journalReview article

342 Scopus citations
17 Scopus citations

Mechanical unfolding intermediates in titin modules

Marszalek, P. E., Lu, H., Li, H., Carrion-Vazquez, M., Oberhauser, A. F., Schulten, K. & Fernandez, J. M., Nov 4 1999, In : Nature. 402, 6757, p. 100-103 4 p.

Research output: Contribution to journalArticle

647 Scopus citations

Mechanical unfolding of spectrin reveals a super-exponential dependence of unfolding rate on force

Renn, J. P., Bhattacharyya, S., Bai, H., He, C., Li, H., Oberhauser, A. F., Marko, J. F., Makarov, D. E. & Matouschek, A., Jul 31 2019, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Multiple conformations of PEVK proteins detected by single-molecule techniques

Li, H., Oberhauser, A. F., Redick, S. D., Carrion-Vazquez, M., Erickson, H. P. & Fernandez, J. M., Sep 11 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 19, p. 10682-10686 5 p.

Research output: Contribution to journalArticle

139 Scopus citations

N-(2-aminoethyl) ethanolamine-induced morphological, biochemical, and biophysical alterations in vascular matrix associated with dissecting aortic aneurysm

Chen, Z., Xu, Y., Bujalowski, P., Oberhauser, A. & Boor, P. J., Dec 1 2015, In : Toxicological Sciences. 148, 2, p. 421-432 12 p., kfv194.

Research output: Contribution to journalArticle

4 Scopus citations

Nanoscale analysis of the effect of pathogenic mutations on polycystin-1

Ma, L., Xu, M. & Oberhauser, A. F., Aug 4 2010, Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. p. 365-366 2 p. (Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Naturally occurring mutations alter the stability of polycystin-1 polycystic kidney disease (PKD) domains

Ma, L., Xu, M., Forman, J. R., Clarke, J. & Oberhauser, A. F., Nov 20 2009, In : Journal of Biological Chemistry. 284, 47, p. 32942-32949 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Naturally occurring osmolytes modulate the nanomechanical properties of polycystic kidney disease domains

Ma, L., Xu, M. & Oberhauser, A. F., Dec 3 2010, In : Journal of Biological Chemistry. 285, 49, p. 38438-38443 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Neurotransmitter release through the exocytotic fusion pore

Monck, J. R., Oberhauser, A. F., Robinson, I. M. & Fernandez, J. M., Jun 1994, In : Seminars in Neuroscience. 6, 3, p. 177-185 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Nucleolin mediates the binding of cancer cells to L-selectin under conditions of lymphodynamic shear stress

Goldson, T. M., Turner, K. L., Huang, Y., Carlson, G. E., Caggiano, E. G., Oberhauser, A. F., Fennewald, S. M., Burdick, M. M. & Resto, V. A., Jan 1 2020, In : American Journal of Physiology - Cell Physiology. 318, 1, p. C83-C93

Research output: Contribution to journalArticle

1 Scopus citations

Patch clamp studies of single intact secretory granules

Oberhauser, A. F. & Fernandez, J. M., Jan 1 1993, In : Biophysical journal. 65, 5, p. 1844-1852 9 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Point mutations alter the mechanical stability of immunoglobulin modules

Li, H., Carrion-Vazquez, M., Oberhauser, A. F., Marszalek, P. E. & Fernandez, J. M., Dec 23 2000, In : Nature Structural Biology. 7, 12, p. 1117-1120 4 p.

Research output: Contribution to journalArticle

170 Scopus citations

Polysaccharide elasticity governed by chair-boat transitions of the glucopyranose ring

Marszalek, P. E., Oberhauser, A. F., Pang, Y. P. & Fernandez, J. M., Dec 17 1998, In : Nature. 396, 6712, p. 661-664 4 p.

Research output: Contribution to journalArticle

369 Scopus citations

Preface

Oberhauser, A., Jan 1 2013, Single-molecule Studies of Proteins. Springer New York, p. v-vii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

1 Scopus citations

Probing a Ca2+-activated K+ channel with quaternary ammonium ions

Villarroel, A., Alvarez, O., Oberhauser, A. & Latorre, R., Dec 1 1988, In : Pflügers Archiv European Journal of Physiology. 413, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

108 Scopus citations

Purification and aggregation of the amyloid precursor protein intracellular domain

El Ayadi, A., Stieren, E. S., Barral, J. M., Oberhauser, A. F. & Boehning, D., Aug 28 2012, In : Journal of Visualized Experiments. 66

Research output: Contribution to journalArticle

Reverse engineering of the giant muscle protein titin

Li, H., Linke, W. A., Oberhauser, A. F., Carrion-Vazquez, M., Kerkvliet, J. G., Lu, H., Marszalek, P. E. & Fernandez, J. M., Aug 29 2002, In : Nature. 418, 6901, p. 998-1002 5 p.

Research output: Contribution to journalArticle

377 Scopus citations
12 Scopus citations

RNA structure: Putting on hair(pins)

Fernandez, J. M., Chu, S. & Oberhauser, A. F., Apr 27 2001, In : Science. 292, 5517, p. 653-654 2 p.

Research output: Contribution to journalShort survey

23 Scopus citations

RT-PCR cloning of Rab3 isoforms expressed in peritoneal mast cells

Oberhauser, A. F., Balan, V., Fernandez-Badilla, C. L. & Fernandez, J. M., Feb 14 1994, In : FEBS Letters. 339, 1-2, p. 171-174 4 p.

Research output: Contribution to journalArticle

34 Scopus citations

Shape of tropoelastin, the highly extensible protein that controls human tissue elasticity

Baldock, C., Oberhauser, A. F., Ma, L., Lammie, D., Siegler, V., Mithieux, S. M., Tu, Y., Chow, J. Y. H., Suleman, F., Malfois, M., Rogers, S., Guo, L., Irving, T. C., Wess, T. J. & Weiss, A. S., Mar 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 11, p. 4322-4327 6 p.

Research output: Contribution to journalArticle

112 Scopus citations

Simultaneous capacitance and amperometric measurements of exocytosis: A comparison

Oberhauser, A. F., Robinson, I. M. & Fernandez, J. M., Aug 1996, In : Biophysical Journal. 71, 2, p. 1131-1139 9 p.

Research output: Contribution to journalArticle

Open Access
62 Scopus citations

Single molecule force spectroscopy of modular proteins in the nervous system

Fisher, T. E., Carrion-Vazquez, M., Oberhauser, A. F., Li, H., Marszalek, P. E. & Fernandez, J. M., Jan 1 2000, In : Neuron. 27, 3, p. 435-446 12 p.

Research output: Contribution to journalReview article

Open Access
37 Scopus citations

Single-molecule force spectroscopy of polycystic kidney disease proteins

Ma, L., Xu, M. & Oberhauser, A. F., Jan 1 2012, Spectroscopic Methods of Analysis: Methods and Protocols. Humana Press Inc., p. 297-310 14 p. (Methods in Molecular Biology; vol. 875).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations