• 8396 Citations
  • 37 h-Index
1988 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article

Activation by divalent cations of a Ca2+-activated K+ channel from skeletal muscle membrane

Oberhauser, A., Alvarez, O. & Latorre, R., Jul 1 1988, In : Journal of General Physiology. 92, 1, p. 67-86 20 p.

Research output: Contribution to journalArticle

Open Access
104 Scopus citations

A fusion pore phenotype in mast cells of the ruby-eye mouse

Oberhauser, A. F. & Fernandez, J. M., Dec 10 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 25, p. 14349-14354 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

A LIM-9 (FHL) / SCPL-1 (SCP) Complex Interacts with the C-terminal Protein Kinase Regions of UNC-89 (Obscurin) in Caenorhabditis elegans Muscle

Xiong, G., Qadota, H., Mercer, K. B., McGaha, L. A., Oberhauser, A. F. & Benian, G. M., Mar 6 2009, In : Journal of Molecular Biology. 386, 4, p. 976-988 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

Analysis of the REJ module of polycystin-1 using molecular modeling and force-spectroscopy techniques

Xu, M., Ma, L., Bujalowski, P. J., Qian, F., Sutton, R. B. & Oberhauser, A. F., 2013, In : Journal of Biophysics. 525231.

Research output: Contribution to journalArticle

3 Scopus citations

A Region of UNC-89 (Obscurin) Lying between Two Protein Kinase Domains Is a Highly Elastic Spring Required for Proper Sarcomere Organization

Qadota, H., Moody, J. C., Lesanpezeshki, L., Moncrief, T., Kitzler, D., Bhat, P. D., Vanapalli, S. A., Oberhauser, A. F. & Benian, G. M., Aug 7 2020, In : Journal of Molecular Biology. 432, 17, p. 4799-4814 16 p.

Research output: Contribution to journalArticle

Atomic force microscopy captures length phenotypes in single proteins

Carrion-Vazquez, M., Marszalek, P. E., Oberhauser, A. F. & Fernandez, J. M., Sep 28 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 20, p. 11288-11292 5 p.

Research output: Contribution to journalArticle

154 Scopus citations

Atomic force microscopy captures quantized plastic deformation in gold nanowires

Marszalek, P. E., Greenleaf, W. J., Li, H., Oberhauser, A. F. & Fernandez, J. M., Jun 6 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 12, p. 6282-6286 5 p.

Research output: Contribution to journalArticle

104 Scopus citations

Atomic force microscopy reveals the mechanical design of a modular protein

Li, H., Oberhauser, A. F., Fowler, S. B., Clarke, J. & Fernandez, J. M., Jun 6 2000, In : Proceedings of the National Academy of Sciences of the United States of America. 97, 12, p. 6527-6531 5 p.

Research output: Contribution to journalArticle

238 Scopus citations

Atomic levers control pyranose ring conformations

Marszalek, P. E., Pang, Y. P., Li, H., El Yazal, J., Oberhauser, A. F. & Fernandez, J. M., Jul 6 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 14, p. 7894-7898 5 p.

Research output: Contribution to journalArticle

130 Scopus citations

Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers: Ion conduction and gating properties

Behrens, M. I., Oberhauser, A., Bezanilla, F. & Latorre, R., Jan 1 1989, In : Journal of General Physiology. 93, 1, p. 23-41 19 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

Bax phosphorylation association with nucleus and oligomerization after neonatal Hypoxia-ischemia

Infante, S. K., Oberhauser, A. F. & Perez-Polo, J. R., Sep 1 2013, In : Journal of Neuroscience Research. 91, 9, p. 1152-1164 13 p.

Research output: Contribution to journalArticle

7 Scopus citations

Chair-boat transitions in single polysaccharide molecules observed with force-ramp AFM

Marszalek, P. E., Li, H., Oberhauser, A. F. & Fernandez, J. M., Apr 2 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 7, p. 4278-4283 6 p.

Research output: Contribution to journalArticle

120 Scopus citations

Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke

Nicholls, P., Bujalowski, P. J., Epstein, H. F., Boehning, D. F., Barral, J. M. & Oberhauser, A. F., Nov 3 2014, In : FEBS Letters. 588, 21, p. 3977-3981 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Do caged-Ca2+ compounds mimic the physiological stimulus for secretion?

Oberhauser, A. F., Robinson, I. M. & Fernandez, J. M., 1995, In : Journal of Physiology - Paris. 89, 2, p. 71-75 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies

Chen, Z., Gu, J., El Ayadi, A., Oberhauser, A. F., Zhou, J., Sousse, L. E., Finnerty, C. C., Herndon, D. N. & Boor, P. J., Jan 1 2019, In : Toxicology and Applied Pharmacology. 362, p. 9-19 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Engineering proteins with enhanced mechanical stability by force-specific sequence motifs

Lu, W., Negi, S. S., Oberhauser, A. F. & Braun, W., May 2012, In : Proteins: Structure, Function and Bioinformatics. 80, 5, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
Open Access
49 Scopus citations

Exocytotic fusion is activated by Rab3a peptides

Oberhauser, A. F., Monck, J. R., Balch, W. E. & Fernandez, J. M., Jan 1 1992, In : Nature. 360, 6401, p. 270-273 4 p.

Research output: Contribution to journalArticle

144 Scopus citations

Hydrophobic ions amplify the capacitive currents used to measure exocytotic fusion

Oberhauser, A. F. & Fernandez, J. M., 1995, In : Biophysical journal. 69, 2, p. 451-459 9 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Inositol (1,4,5)-trisphosphate activates a calcium channel in isolated sarcoplasmic reticulum membranes

Suárez-Isla, B. A., Irribarra, V., Oberhauser, A., Larralde, L., Bull, R., Hidalgo, C. & Jaimovich, E., 1988, In : Biophysical journal. 54, 4, p. 737-741 5 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

Is swelling of the secretory granule matrix the force that dilates the exocytotic fusion pore?

Monck, J. R., Oberhauser, A. F., Alvarez de Toledo, G. & Fernandez, J. M., 1991, In : Biophysical journal. 59, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Is the Activity of the Fusion Pore Scaffold Regulated by a Coincidence Detector?

ROBINSON, IAIN. M., OBERHAUSER, ANDRES. F. & FERNANDEZ, JULIO. M., Mar 1994, In : Annals of the New York Academy of Sciences. 710, 1, p. 168-178 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mechanical and chemical unfolding of a single protein: A comparison

Carrion-Vazquez, M., Oberhauser, A. F., Fowler, S. B., Marszalek, P. E., Broedel, S. E., Clarke, J. & Fernandez, J. M., Mar 30 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 7, p. 3694-3699 6 p.

Research output: Contribution to journalArticle

825 Scopus citations
17 Scopus citations

Mechanical unfolding intermediates in titin modules

Marszalek, P. E., Lu, H., Li, H., Carrion-Vazquez, M., Oberhauser, A. F., Schulten, K. & Fernandez, J. M., Nov 4 1999, In : Nature. 402, 6757, p. 100-103 4 p.

Research output: Contribution to journalArticle

652 Scopus citations

Mechanical unfolding of spectrin reveals a super-exponential dependence of unfolding rate on force

Renn, J. P., Bhattacharyya, S., Bai, H., He, C., Li, H., Oberhauser, A. F., Marko, J. F., Makarov, D. E. & Matouschek, A., Jul 31 2019, In : Scientific reports. 9, 1, p. 11101 1 p., 11101.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Multiple conformations of PEVK proteins detected by single-molecule techniques

Li, H., Oberhauser, A. F., Redick, S. D., Carrion-Vazquez, M., Erickson, H. P. & Fernandez, J. M., Sep 11 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 19, p. 10682-10686 5 p.

Research output: Contribution to journalArticle

139 Scopus citations

N-(2-aminoethyl) ethanolamine-induced morphological, biochemical, and biophysical alterations in vascular matrix associated with dissecting aortic aneurysm

Chen, Z., Xu, Y., Bujalowski, P., Oberhauser, A. F. & Boor, P. J., Dec 1 2015, In : Toxicological Sciences. 148, 2, p. 421-432 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Naturally occurring mutations alter the stability of polycystin-1 polycystic kidney disease (PKD) domains

Ma, L., Xu, M., Forman, J. R., Clarke, J. & Oberhauser, A. F., Nov 20 2009, In : Journal of Biological Chemistry. 284, 47, p. 32942-32949 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Naturally occurring osmolytes modulate the nanomechanical properties of polycystic kidney disease domains

Ma, L., Xu, M. & Oberhauser, A. F., Dec 3 2010, In : Journal of Biological Chemistry. 285, 49, p. 38438-38443 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Neurotransmitter release through the exocytotic fusion pore

Monck, J. R., Oberhauser, A. F., Robinson, I. M. & Fernandez, J. M., Jun 1994, In : Seminars in Neuroscience. 6, 3, p. 177-185 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Nucleolin mediates the binding of cancer cells to L-selectin under conditions of lymphodynamic shear stress

Goldson, T. M., Turner, K. L., Huang, Y., Carlson, G. E., Caggiano, E. G., Oberhauser, A. F., Fennewald, S., Burdick, M. M. & Resto, V. A., Jan 1 2020, In : American Journal of Physiology - Cell Physiology. 318, 1, p. C83-C93

Research output: Contribution to journalArticle

1 Scopus citations

Patch clamp studies of single intact secretory granules

Oberhauser, A. F. & Fernandez, J. M., 1993, In : Biophysical journal. 65, 5, p. 1844-1852 9 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Point mutations alter the mechanical stability of immunoglobulin modules

Li, H., Carrion-Vazquez, M., Oberhauser, A. F., Marszalek, P. E. & Fernandez, J. M., Dec 23 2000, In : Nature Structural Biology. 7, 12, p. 1117-1120 4 p.

Research output: Contribution to journalArticle

171 Scopus citations

Polysaccharide elasticity governed by chair-boat transitions of the glucopyranose ring

Marszalek, P. E., Oberhauser, A. F., Pang, Y. P. & Fernandez, J. M., Dec 17 1998, In : Nature. 396, 6712, p. 661-664 4 p.

Research output: Contribution to journalArticle

370 Scopus citations

Probing a Ca2+-activated K+ channel with quaternary ammonium ions

Villarroel, A., Alvarez, O., Oberhauser, A. & Latorre, R., Dec 1 1988, In : Pflügers Archiv European Journal of Physiology. 413, 2, p. 118-126 9 p.

Research output: Contribution to journalArticle

108 Scopus citations

Purification and aggregation of the amyloid precursor protein intracellular domain

El Ayadi, A., Stieren, E. S., Barral, J. M., Oberhauser, A. F. & Boehning, D., Aug 28 2012, In : Journal of Visualized Experiments. 66

Research output: Contribution to journalArticle

Reverse engineering of the giant muscle protein titin

Li, H., Linke, W. A., Oberhauser, A. F., Carrion-Vazquez, M., Kerkvliet, J. G., Lu, H., Marszalek, P. E. & Fernandez, J. M., Aug 29 2002, In : Nature. 418, 6901, p. 998-1002 5 p.

Research output: Contribution to journalArticle

382 Scopus citations

Rickettsiae induce microvascular hyperpermeability via phosphorylation of ve-cadherins: Evidence from atomic force microscopy and biochemical studies

Gong, B., Ma, L., Liu, Y., Gong, Q., Shelite, T., Bouyer, D., Boor, P. J., Lee, Y. S. & Oberhauser, A., Jun 2012, In : PLoS neglected tropical diseases. 6, 6, e1699.

Research output: Contribution to journalArticle

12 Scopus citations

RT-PCR cloning of Rab3 isoforms expressed in peritoneal mast cells

Oberhauser, A. F., Balan, V., Fernandez-Badilla, C. L. & Fernandez, J. M., Feb 14 1994, In : FEBS Letters. 339, 1-2, p. 171-174 4 p.

Research output: Contribution to journalArticle

35 Scopus citations

Shape of tropoelastin, the highly extensible protein that controls human tissue elasticity

Baldock, C., Oberhauser, A. F., Ma, L., Lammie, D., Siegler, V., Mithieux, S. M., Tu, Y., Chow, J. Y. H., Suleman, F., Malfois, M., Rogers, S., Guo, L., Irving, T. C., Wess, T. J. & Weiss, A. S., Mar 15 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 11, p. 4322-4327 6 p.

Research output: Contribution to journalArticle

116 Scopus citations

Simultaneous capacitance and amperometric measurements of exocytosis: A comparison

Oberhauser, A. F., Robinson, I. M. & Fernandez, J. M., Aug 1996, In : Biophysical journal. 71, 2, p. 1131-1139 9 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations

Single protein misfolding events captured by atomic force microscopy

Oberhauser, A. F., Marszalek, P. E., Carrion-Vazquez, M. & Fernandez, J. M., Nov 17 1999, In : Nature Structural Biology. 6, 11, p. 1025-1028 4 p.

Research output: Contribution to journalArticle

163 Scopus citations

Stepwise unfolding of titin under force-clamp atomic force microscopy

Oberhauser, A. F., Hansma, P. K., Carrion-Vazquez, M. & Fernandez, J. M., Jan 16 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 98, 2, p. 468-472 5 p.

Research output: Contribution to journalArticle

Open Access
330 Scopus citations

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

Holst, J., Watson, S., Lord, M. S., Eamegdool, S. S., Bax, D. V., Nivison-Smith, L. B., Kondyurin, A., Ma, L., Oberhauser, A. F., Weiss, A. S. & Rasko, J. E. J., Oct 1 2010, In : Nature Biotechnology. 28, 10, p. 1123-1128 6 p.

Research output: Contribution to journalArticle

186 Scopus citations

The C2 domains of human synaptotagmin 1 have distinct mechanical properties

Fuson, K. L., Liang, M., Sutton, R. B. & Oberhauser, A. F., Feb 4 2009, In : Biophysical journal. 96, 3, p. 1083-1090 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

The central domain of UNC-45 chaperone inhibits the myosin power stroke

Bujalowski, P. J., Nicholls, P., Garza, E. & Oberhauser, A. F., Jan 2018, In : FEBS Open Bio. 8, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

The exocytotic fusion pore interface: A model of the site of neurotransmitter release

Monck, J. R., Oberhauser, A. F. & Fernandez, J. M., Jan 1 1995, In : Molecular membrane biology. 12, 1, p. 151-156 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

The exocytotic fusion pore modeled as a lipidic pore

Nanavati, C., Markin, V. S., Oberhauser, A. F. & Fernandez, J. M., 1992, In : Biophysical journal. 63, 4, p. 1118-1132 15 p.

Research output: Contribution to journalArticle

Open Access
90 Scopus citations

The force-driven conformations of heparin studied with single molecule force microscopy

Marszalek, P. E., Oberhauser, A. F., Li, H. & Fernandez, J. M., Oct 1 2003, In : Biophysical journal. 85, 4, p. 2696-2704 9 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations