• 4659 Citations
  • 42 h-Index
1995 …2021
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Personal profile

Member, Institute for Human Infections & Immunity

Dr. Casola is a physician-scientist specialized in pediatric infectious diseases, with research expertise in the area of respiratory viral pathogens, lung inflammation, and cell signaling. Her research is focused on the investigation of viral- and host-specific mechanisms that contribute to the pathogenesis of respiratory viral infections. Over the past several years, she has identified several inducible intracellular signaling pathways activated by respiratory syncytial virus (RSV) in airway epithelial cells with particular emphasis on the role of reactive oxygen species in RSV induced lung inflammation both in vitro and in vivo, using a mouse model of RSV infection. Her research efforts include investigating the pathogenesis of respiratory diseases caused by human metapneumovirus (hMPV). Her laboratory uses recombinant hMPV viruses to investigate specific viral protein functions, with the ultimate goal to understand disease pathogenesis and design effective vaccines.

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 17 Similar Profiles
Respiratory Syncytial Viruses Medicine & Life Sciences
Metapneumovirus Medicine & Life Sciences
Respiratory Syncytial Virus Infections Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
viruses Agriculture & Biology
Human metapneumovirus Agriculture & Biology
Interleukin-8 Medicine & Life Sciences
Chemokines Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2010 2021

Research Output 1995 2019

  • 4659 Citations
  • 42 h-Index
  • 87 Article
  • 3 Review article
Virus Diseases

Human metapneumovirus infection of airway epithelial cells is associated with changes in core metabolic pathways

Zhao, Y., Chahar, H. S., Komaravelli, N., Dossumekova, A. & Casola, A., May 1 2019, In : Virology. 531, p. 183-191 9 p.

Research output: Contribution to journalArticle

Metabolic Networks and Pathways
Epithelial Cells
1 Citation (Scopus)

Human metapneumovirus small hydrophobic protein inhibits interferon induction in plasmacytoid dendritic cells

Bao, X., Kolli, D., Esham, D., Velayutham, T. S. & Casola, A., Jun 1 2018, In : Viruses. 10, 6, 278.

Research output: Contribution to journalArticle

Dendritic Cells
TNF Receptor-Associated Factor 6
Interferon Type I
1 Citation (Scopus)
Respiratory Syncytial Viruses
Airway Obstruction
6 Citations (Scopus)

Respiratory Syncytial Virus Infection Changes Cargo Composition of Exosome Released from Airway Epithelial Cells

Chahar, H. S., Gorgun, T., Kudlicki, A. S., Komaravelli, N. & Casola, A., Dec 1 2018, In : Scientific Reports. 8, 1, 387.

Research output: Contribution to journalArticle

Respiratory Syncytial Virus Infections
Epithelial Cells
Respiratory Syncytial Viruses