Bartosz Szczesny, PhD, MS

  • 1854 Citations
  • 25 h-Index
20022019
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Projects 2015 2018

Research Output 2002 2019

  • 1854 Citations
  • 25 h-Index
  • 48 Article

The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis

Ahmad, A., Vieira, J. D. C., Haas de Mello, A., de Lima, T. M., Ariga, S. K., Barbeiro, D. F., Barbeiro, H. V., Szczesny, B., Törö, G., Druzhyna, N., Randi, E. B., Marcatti, M., Toliver-Kinsky, T., Kiss, A., Liaudet, L., Salomao, R., Soriano, F. G. & Szabo, C., Jul 1 2019, In : Pharmacological Research. 145, 104263.

Research output: Contribution to journalArticle

Investigational Therapies
Punctures
Ligation
Sepsis
Oxidative Stress
3 Citations (Scopus)

Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection

Ibitokou, A. A. A., Dillon, B. E., Sinha, M., Szczesny, B., Delgadillo, A., Abdelrahman, D. R., Szabo, C., Abu-Elheiga, L., Porter, C., Tuvdendorj, D. & Stephens, R., Jan 15 2018, In : Journal of Immunology. 200, 2, p. 643-656 14 p.

Research output: Contribution to journalArticle

T-Lymphoid Precursor Cells
Eragrostis
Fatty Acids
Infection
T-Lymphocytes
13 Citations (Scopus)

Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells

Szczesny, B., Marcatti, M., Ahmad, A., Montalbano, M., Brunyánszki, A., Bibli, S. I., Papapetropoulos, A. & Szabo, C., Dec 1 2018, In : Scientific Reports. 8, 1, 914.

Research output: Contribution to journalArticle

Z-Form DNA
DNA-Binding Proteins
Mitochondrial DNA
DNA Damage
Oxidative Stress
6 Citations (Scopus)

Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats

Korkmaz-Icöz, S., Szczesny, B., Marcatti, M., Li, S., Ruppert, M., Lasitschka, F., Loganathan, S., Szabo, C. & Szabó, G., Jan 1 2018, In : British Journal of Pharmacology. 175, 2, p. 246-261 16 p.

Research output: Contribution to journalArticle

Heart Transplantation
Cardiac Myocytes
Oxidative Stress
Transplants
Poly(ADP-ribose) Polymerases
5 Citations (Scopus)

Pentose phosphate shunt modulates reactive oxygen species and nitric oxide production controlling Trypanosoma cruzi in Macrophages

Koo, S. J., Szczesny, B., Wan, X., Putluri, N. & Garg, N., Feb 16 2018, In : Frontiers in Immunology. 9, FEB, 202.

Research output: Contribution to journalArticle

Pentose Phosphate Pathway
Trypanosoma cruzi
Reactive Oxygen Species
Nitric Oxide
Macrophages