Bartosz Szczesny, PhD, MS

  • 1892 Citations
  • 26 h-Index
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  • 8 Similar Profiles
Hydrogen Sulfide Medicine & Life Sciences
Mitochondrial DNA Medicine & Life Sciences
Oxidative Stress Medicine & Life Sciences
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Energy Metabolism Medicine & Life Sciences
Cystathionine Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
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Projects 2015 2018

Research Output 2002 2019

  • 1892 Citations
  • 26 h-Index
  • 48 Article

The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis

Ahmad, A., Vieira, J. D. C., Haas de Mello, A., de Lima, T. M., Ariga, S. K., Barbeiro, D. F., Barbeiro, H. V., Szczesny, B., Törö, G., Druzhyna, N., Randi, E. B., Marcatti, M., Toliver-Kinsky, T., Kiss, A., Liaudet, L., Salomao, R., Soriano, F. G. & Szabo, C., Jul 1 2019, In : Pharmacological Research. 145, 104263.

Research output: Contribution to journalArticle

Investigational Therapies
Oxidative Stress
4 Citations (Scopus)

Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection

Ibitokou, A. A. A., Dillon, B. E., Sinha, M., Szczesny, B., Delgadillo, A., Abdelrahman, D. R., Szabo, C., Abu-Elheiga, L., Porter, C., Tuvdendorj, D. & Stephens, R., Jan 15 2018, In : Journal of Immunology. 200, 2, p. 643-656 14 p.

Research output: Contribution to journalArticle

T-Lymphoid Precursor Cells
Fatty Acids
16 Citations (Scopus)

Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells

Szczesny, B., Marcatti, M., Ahmad, A., Montalbano, M., Brunyánszki, A., Bibli, S. I., Papapetropoulos, A. & Szabo, C., Dec 1 2018, In : Scientific Reports. 8, 1, 914.

Research output: Contribution to journalArticle

Z-Form DNA
DNA-Binding Proteins
Mitochondrial DNA
DNA Damage
Oxidative Stress
6 Citations (Scopus)

Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats

Korkmaz-Icöz, S., Szczesny, B., Marcatti, M., Li, S., Ruppert, M., Lasitschka, F., Loganathan, S., Szabo, C. & Szabó, G., Jan 1 2018, In : British Journal of Pharmacology. 175, 2, p. 246-261 16 p.

Research output: Contribution to journalArticle

Heart Transplantation
Cardiac Myocytes
Oxidative Stress
Poly(ADP-ribose) Polymerases
9 Citations (Scopus)

Pentose phosphate shunt modulates reactive oxygen species and nitric oxide production controlling Trypanosoma cruzi in Macrophages

Koo, S. J., Szczesny, B., Wan, X., Putluri, N. & Garg, N., Feb 16 2018, In : Frontiers in Immunology. 9, FEB, 202.

Research output: Contribution to journalArticle

Pentose Phosphate Pathway
Trypanosoma cruzi
Reactive Oxygen Species
Nitric Oxide