Bin Gong, MD, PhD

  • 634 Citations
  • 17 h-Index
20032021
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Research Output 2003 2019

  • 634 Citations
  • 17 h-Index
  • 35 Article
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Article
2019

A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study

He, X., Zhang, W., Chang, Q., Su, Z., Gong, D., Zhou, Y., Xiao, J., Drelich, A., Liu, Y., Popov, V., Zhao, X., Wakamiya, M., Gaitas, A., Lu, F. & Gong, B., Jan 1 2019, In : Laboratory Investigation.

Research output: Contribution to journalArticle

Annexin A2
Bacterial Adhesion
Atomic Force Microscopy
Endothelial Cells
Cell Line
Antibodies
Rabbits
Direct Fluorescent Antibody Technique
Indirect Fluorescent Antibody Technique
Antigens

Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis

He, X., Drelich, A., Yu, S., Chang, Q., Gong, D., Zhou, Y., Qu, Y., Yuan, Y., Su, Z., Qiu, Y., Tang, S-J., Gaitas, A., Ksiazek, T., Xu, Z., Zhou, J., Feng, Z., Wakamiya, M., Lu, F. & Gong, B., Mar 15 2019, In : Life Sciences. 221, p. 1-12 12 p.

Research output: Contribution to journalArticle

Annexin A2
Endothelial cells
Fibrinolysis
Blood Vessels
Endothelial Cells
2018
2 Citations (Scopus)

Exchange protein directly activated by cAMP modulates ebola virus uptake into vascular endothelial cells

Drelich, A., Judy, B., He, X., Chang, Q., Yu, S., Li, X., Lu, F., Wakamiya, M., Popov, V., Zhou, J., Ksiazek, T. & Gong, B., Oct 16 2018, In : Viruses. 10, 10, 563.

Research output: Contribution to journalArticle

Ebolavirus
Endothelial Cells
Ebola Hemorrhagic Fever
Marburgvirus
Proteins
2016
6 Citations (Scopus)

Attenuation of pathogenic Rift Valley fever virus strain through the chimeric S-segment encoding sandfly fever phlebovirus NSs or a dominant-negative PKR

Nishiyama, S., Slack, O. A. L., Lokugamage, N., Hill, T. E., Juelich, T. L., Zhang, L., Smith, J. K., Perez, D., Gong, B., Freiberg, A. & Ikegami, T., Jun 16 2016, (Accepted/In press) In : Virulence. p. 1-11 11 p.

Research output: Contribution to journalArticle

Phlebotomus Fever
Phlebovirus
Rift Valley fever virus
Sandfly fever Naples virus
Vaccines
13 Citations (Scopus)

IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi-Infected Mice

Shelite, T., Liang, Y., Wang, H., Mendell, N. L., Trent, B., Sun, J., Gong, B., Xu, G., Hu, H., Bouyer, D. & Soong, L., Mar 4 2016, In : PLoS Neglected Tropical Diseases. 10, 3, e0004467.

Research output: Contribution to journalArticle

Orientia tsutsugamushi
Apoptosis
Kidney
Endothelial Cells
Wounds and Injuries
2015
44 Citations (Scopus)

Interleukin (IL)-21 promotes intestinal IgA response to microbiota

Cao, A. T., Yao, S., Gong, B., Nurieva, R. I., Elson, C. O. & Cong, Y., Sep 19 2015, In : Mucosal Immunology. 8, 5, p. 1072-1082 11 p.

Research output: Contribution to journalArticle

Microbiota
Immunoglobulin A
B-Lymphocytes
Immunoglobulin Isotypes
Genetic Recombination
21 Citations (Scopus)

Rift Valley fever virus MP-12 vaccine is fully attenuated by a combination of partial attenuations in the S, M, and L segments

Ikegami, T., Hill, T. E., Smith, J. K., Zhang, L., Juelich, T. L., Gong, B., Slack, O. A. L., Ly, H. J., Lokugamage, N. & Freiberg, A., 2015, In : Journal of Virology. 89, 14, p. 7262-7276 15 p.

Research output: Contribution to journalArticle

Rift Valley fever virus
Rift Valley Fever
Rift Valley fever
Vaccines
vaccines
2014
17 Citations (Scopus)

A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus

Shelite, T., Saito, T., Mendell, N. L., Gong, B., Xu, G., Soong, L., Valbuena, G., Bouyer, D. & Walker, D., 2014, In : PLoS Neglected Tropical Diseases. 8, 7, e2966.

Research output: Contribution to journalArticle

Scrub Typhus
Orientia tsutsugamushi
Infection
Inbred C57BL Mouse
Trombiculidae
16 Citations (Scopus)

Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice

Soong, L., Wang, H., Shelite, T., Liang, Y., Mendell, N. L., Sun, J., Gong, B., Valbuena, G. A., Bouyer, D. & Walker, D., Sep 1 2014, In : PLoS Neglected Tropical Diseases. 8, 9

Research output: Contribution to journalArticle

Orientia tsutsugamushi
Scrub Typhus
Angiopoietin-2
Pathology
Angiopoietin-1
2013
21 Citations (Scopus)

A Hamster-Derived West Nile Virus Isolate Induces Persistent Renal Infection in Mice

Saxena, V., Xie, G., Li, B., Farris, T., Welte, T., Gong, B., Boor, P., Wu, P., Tang, S-J., Tesh, R. & Wang, T., Jun 2013, In : PLoS Neglected Tropical Diseases. 7, 6, e2275.

Research output: Contribution to journalArticle

West Nile virus
Cricetinae
Kidney
Infection
Spleen
33 Citations (Scopus)

Cell death/proliferation roles for nc886, a non-coding RNA, in the protein kinase R pathway in cholangiocarcinoma

Kunkeaw, N., Jeon, S. H., Lee, K., Johnson, B. H., Tanasanvimon, S., Javle, M., Pairojkul, C., Chamgramol, Y., Wongfieng, W., Gong, B., Leelayuwat, C. & Lee, Y. S., Aug 8 2013, In : Oncogene. 32, 32, p. 3722-3731 10 p.

Research output: Contribution to journalArticle

Untranslated RNA
Cholangiocarcinoma
Protein Kinases
Cell Death
Cell Proliferation
20 Citations (Scopus)

Characterization of Rift Valley Fever Virus MP-12 Strain Encoding NSs of Punta Toro Virus or Sandfly Fever Sicilian Virus

Lihoradova, O. A., Indran, S. V., Kalveram, B., Lokugamage, N., Head, J. A., Gong, B., Tigabu, B., Juelich, T. L., Freiberg, A. & Ikegami, T., Apr 2013, In : PLoS Neglected Tropical Diseases. 7, 4, e2181.

Research output: Contribution to journalArticle

Phlebovirus
Rift Valley fever virus
Viruses
Interferon Type I
Vaccines
18 Citations (Scopus)

Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs

Gong, B., Lee, Y. S., Lee, I., Shelite, T., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D., Boor, P. J., Ksiazek, T. & Walker, D., Jun 23 2013, In : BMC Infectious Diseases. 13, 1, 285.

Research output: Contribution to journalArticle

Rickettsia
Small Untranslated RNA
Transfer RNA
Fever
RNA
Metapneumovirus
Immune System Diseases
Viruses
Lung
corrigendum
36 Citations (Scopus)

Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses

Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T., Boor, P. J., Bouyer, D., Popov, V., Chen, J., Walker, D. & Cheng, X., Nov 26 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.

Research output: Contribution to journalArticle

Rickettsia
Bacterial Adhesion
Bioterrorism
Host-Pathogen Interactions
Proteins
8 Citations (Scopus)

MyD88 controls human metapneumovirus-induced pulmonary immune responses and disease pathogenesis

Ren, J., Kolli, D., Deng, J., Fang, R., Gong, B., Xue, M., Casola, A., Garafalo, R. P., Wang, T. & Bao, X., Sep 2013, In : Virus Research. 176, 1-2, p. 241-250 10 p.

Research output: Contribution to journalArticle

Metapneumovirus
Immune System Diseases
Lung
Infection
Toll-Like Receptors
11 Citations (Scopus)

Rift valley fever virus MP-12 vaccine encoding toscana virus NSs retains neuroinvasiveness in mice

Indran, S. V., Lihoradova, O. A., Phoenix, I., Lokugamage, N., Kalveram, B., Head, J. A., Tigabu, B., Smith, J. K., Zhang, L., Juelich, T. L., Gong, B., Freiberg, A. & Ikegami, T., Jul 1 2013, In : Journal of General Virology. 94, PART7, p. 1441-1450 10 p.

Research output: Contribution to journalArticle

Sandfly fever Naples virus
Rift Valley fever virus
Vaccines
Viral Antigens
Ruminants

The Dominant-negative inhibition of double-stranded RNA-Dependent protein kinase PKR increases the efficacy of rift valley fever virus MP-12 vaccine

Lihoradova, O., Kalveram, B., Indran, S. V., Lokugamage, N., Juelich, T. L., Hill, T. E., Tseng, C-T., Gong, B., Fukushi, S., Morikawa, S., Freiberg, A. & Ikegami, T., 2013, In : Journal of Virology. 87, 22, p. 12507 1 p.

Research output: Contribution to journalArticle

Rift Valley fever virus
double-stranded RNA
protein kinases
vaccines
2012
27 Citations (Scopus)

Characterization of the direct physical interaction of nc886, a cellular non-coding RNA, and PKR

Jeon, S. H., Lee, K., Lee, K. S., Kunkeaw, N., Johnson, B. H., Holthauzen, L. M. F., Gong, B., Leelayuwat, C. & Lee, Y. S., Sep 21 2012, In : FEBS Letters. 586, 19, p. 3477-3484 8 p.

Research output: Contribution to journalArticle

Untranslated RNA
Double-Stranded RNA
Chemical activation
RNA
Virus Diseases
11 Citations (Scopus)
Rickettsia
Atomic Force Microscopy
Cadherins
Fever
Endothelial Cells
14 Citations (Scopus)
rickettsial diseases
Indoleamine-Pyrrole 2,3,-Dioxygenase
T-cells
death
Oligodeoxyribonucleotides
110 Citations (Scopus)

Th17 cells upregulate polymeric Ig receptor and intestinal IgA and contribute to intestinal homeostasis

Cao, A. T., Yao, S., Gong, B., Elson, C. O. & Cong, Y., Nov 1 2012, In : Journal of Immunology. 189, 9, p. 4666-4673 8 p.

Research output: Contribution to journalArticle

Polymeric Immunoglobulin Receptors
Th17 Cells
Immunoglobulin A
Homeostasis
Up-Regulation
17 Citations (Scopus)

The dominant-negative inhibition of double-stranded RNA-dependent protein kinase PKR increases the efficacy of rift valley fever virus MP-12 vaccine

Lihoradova, O., Kalveram, B., Indran, S. V., Lokugamage, N., Juelich, T. L., Hill, T. E., Tseng, C-T., Gong, B., Fukushi, S., Morikawa, S., Freiberg, A. & Ikegami, T., Jul 2012, In : Journal of Virology. 86, 14, p. 7650-7661 12 p.

Research output: Contribution to journalArticle

Rift Valley fever virus
eIF-2 Kinase
Double-Stranded RNA
double-stranded RNA
protein kinases
2011
23 Citations (Scopus)

Differential, type i interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver

Desai, M. M., Gong, B., Chan, T., Davey, R. A., Soong, L., Kolokoltsov, A. A. & Sun, J., Aug 2011, In : Gastroenterology. 141, 2

Research output: Contribution to journalArticle

Hepacivirus
Interferons
Interferon-beta
Antiviral Agents
Mitochondria
21 Citations (Scopus)

Vγ4+ T cells regulate host immune response to West Nile virus infection

Welte, T., Aronson, J., Gong, B., Rachamallu, A., Mendell, N., Tesh, R., Paessler, S., Born, W. K., O'Brien, R. L. & Wang, T., Nov 2011, In : FEMS Immunology and Medical Microbiology. 63, 2, p. 183-192 10 p.

Research output: Contribution to journalArticle

West Nile virus
Virus Diseases
T-Lymphocytes
Interleukin-17
Viremia
2010
13 Citations (Scopus)

Adenovirus-mediated overexpression of glutathione-s-transferase mitigates transplant arteriosclerosis in rabbit carotid allografts

Xu, Y., Gong, B., Yang, Y., Awasthi, Y. C. & Boor, P. J., Feb 2010, In : Transplantation. 89, 4, p. 409-416 8 p.

Research output: Contribution to journalArticle

Arteriosclerosis
Glutathione Transferase
Adenoviridae
Allografts
Rabbits
2008
4 Citations (Scopus)

Cardiac Preconditioning With Local Laser-Induced Hyperthermia

Gong, B., Bell, B., Boor, P. J., Albrecht, T. B., Asimakis, G. K. & Motamedi, M., Oct 2008, In : Journal of Surgical Research. 149, 2, p. 177-183 7 p.

Research output: Contribution to journalArticle

Induced Hyperthermia
Lasers
Fever
Semiconductor Lasers
Reperfusion Injury
14 Citations (Scopus)
Dissecting Aneurysm
Collagen Type III
Aortic Aneurysm
Elastin
Extracellular Matrix
2007
19 Citations (Scopus)

Glutathione-S-transferase protects against oxidative injury of endothelial cell tight junctions

Xu, Y., Gong, B., Yang, Y., Awasthi, Y. C., Woods, M. & Boor, P. J., Nov 2007, In : Endothelium: Journal of Endothelial Cell Research. 14, 6, p. 333-343 11 p.

Research output: Contribution to journalArticle

Intercellular Junctions
Tight Junctions
Glutathione Transferase
Endothelial Cells
Occludin
2006
20 Citations (Scopus)

Chemical-induced, nonlethal, developmental model of dissecting aortic aneurysm

Gong, B., Trent, M. B., Srivastava, D. & Boor, P. J., Jan 2006, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 76, 1, p. 29-38 10 p.

Research output: Contribution to journalArticle

Dissecting Aneurysm
Aortic Aneurysm
Tunica Media
Elastin
Amine Oxidase (Copper-Containing)
5 Citations (Scopus)

Role of the media in vascular injury: Atherosclerosis and dissection

Boor, P., Yang, Y. & Gong, B., 2006, In : Toxicologic Pathology. 34, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

Dissection
Poisons
Vascular System Injuries
Atherosclerosis
Vascular Smooth Muscle
30 Citations (Scopus)

The role of amine oxidases in xenobiotic metabolism

Gong, B. & Boor, P. J., 2006, In : Expert Opinion on Drug Metabolism and Toxicology. 2, 4, p. 559-571 13 p.

Research output: Contribution to journalArticle

Xenobiotics
Metabolism
Amines
Amine Oxidase (Copper-Containing)
Oxidoreductases
23 Citations (Scopus)

Whole-body hyperthermia induces up-regulation of vascular endothelial growth factor accompanied by neovascularization in cardiac tissue

Gong, B., Asimakis, G. K., Chen, Z., Albrecht, T. B., Boor, P. J., Pappas, T. C., Bell, B. & Motamedi, M., Oct 4 2006, In : Life Sciences. 79, 19, p. 1781-1788 8 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Fever
Up-Regulation
Tissue
Endothelial cells
2003
17 Citations (Scopus)

Potential inhibition of cytochrome P450 3A4 by propofol in human primary hepatocytes

Yang, L. Q., Yu, W. F., Cao, Y. F., Gong, B., Chang, Q. & Yang, G. S., Sep 15 2003, In : World Journal of Gastroenterology. 9, 9, p. 1959-1962 4 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Propofol
Hepatocytes
Liver
Drug Interactions