Chad Mire, PhD

  • 1579 Citations
  • 25 h-Index
20042020
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Research Output 2004 2019

2015
64 Citations (Scopus)

Single-dose attenuated Vesiculovax vaccines protect primates against Ebola Makona virus

Mire, C., Matassov, D., Geisbert, J. B., Latham, T. E., Agans, K. N., Xu, R., Ota-Setlik, A., Egan, M. A., Fenton, K. A., Clarke, D. K., Eldridge, J. H. & Geisbert, T., Apr 30 2015, In : Nature. 520, 7549, p. 688-691 4 p.

Research output: Contribution to journalArticle

Ebolavirus
Attenuated Vaccines
Democratic Republic of the Congo
Primates
Vaccines
21 Citations (Scopus)

The immunomodulating v and W proteins of Nipah virus determine disease course

Satterfield, B. A., Cross, R., Fenton, K. A., Agans, K. N., Basler, C. F., Geisbert, T. & Mire, C., Jun 24 2015, In : Nature Communications. 6, 7483.

Research output: Contribution to journalArticle

viruses
Virus Diseases
Nipah Virus
Viruses
proteins
28 Citations (Scopus)

Vaccination with a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge with a Lethal Dose of Ebola Virus

Matassov, D., Marzi, A., Latham, T., Xu, R., Ota-Setlik, A., Feldmann, F., Geisbert, J. B., Mire, C., Hamm, S., Nowak, B., Egan, M. A., Geisbert, T., Eldridge, J. H., Feldmann, H. & Clarke, D. K., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S443-S451

Research output: Contribution to journalArticle

Ebolavirus
Vesicular Stomatitis
Vaccination
Viruses
Glycoproteins
2014
19 Citations (Scopus)

A recombinant Hendra Virus G glycoprotein subunit vaccine protects nonhuman primates against hendra virus challenge

Mire, C., Geisbert, J. B., Agans, K. N., Feng, Y. R., Fenton, K. A., Bossart, K. N., Yan, L., Chan, Y. P., Broder, C. C. & Geisbert, T., 2014, In : Journal of Virology. 88, 9, p. 4624-4631 8 p.

Research output: Contribution to journalArticle

Hendra Virus
Hendra virus
Subunit Vaccines
subunit vaccines
Primates

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells

Shabman, R. S., Jabado, O. J., Mire, C. E., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. W. & Basler, C. F., 2014, In : mBio. 5, 6, p. e02011

Research output: Contribution to journalArticle

Marburgvirus
Ebolavirus
High-Throughput Nucleotide Sequencing
RNA
Messenger RNA
42 Citations (Scopus)

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAS in infected cells

Shabman, R. S., Jabado, O. J., Mire, C., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. & Basler, C. F., Sep 25 2014, In : mBio. 5, 6, e02011-14.

Research output: Contribution to journalArticle

Marburgvirus
Ebolavirus
High-Throughput Nucleotide Sequencing
Messenger RNA
Nucleoproteins
40 Citations (Scopus)

Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates

Mire, C., Geisbert, J. B., Agans, K. N., Satterfield, B. A., Versteeg, K. M., Fritz, E. A., Feldmann, H., Hensley, L. E. & Geisbert, T., Apr 23 2014, In : PLoS One. 9, 4, e94355.

Research output: Contribution to journalArticle

Marburg virus
Marburgvirus
Vesiculovirus
Vesicular Stomatitis
Filoviridae
44 Citations (Scopus)

Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA

Thi, E. P., Mire, C., Ursic-Bedoya, R., Geisbert, J. B., Lee, A. C. H., Agans, K. N., Robbins, M., Deer, D. J., Fenton, K. A., MacLachlan, I. & Geisbert, T., Aug 20 2014, In : Science Translational Medicine. 6, 250, 250ra116.

Research output: Contribution to journalArticle

Marburgvirus
Virus Diseases
Angola
Primates
Small Interfering RNA
28 Citations (Scopus)

Protection against lethal marburg virus infection mediated by lipid encapsulated small interfering RNA

Ursic-Bedoya, R., Mire, C., Robbins, M., Geisbert, J. B., Judge, A., MacLachlan, I. & Geisbert, T., Feb 15 2014, In : Journal of Infectious Diseases. 209, 4, p. 562-570 9 p.

Research output: Contribution to journalArticle

Marburgvirus
Virus Diseases
Small Interfering RNA
Lipids
Angola
53 Citations (Scopus)

The Marburg Virus VP24 Protein Interacts with Keap1 to Activate the Cytoprotective Antioxidant Response Pathway

Edwards, M. R., Johnson, B., Mire, C., Xu, W., Shabman, R. S., Speller, L. N., Leung, D. W., Geisbert, T., Amarasinghe, G. K. & Basler, C. F., Mar 27 2014, In : Cell Reports. 6, 6, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

Antioxidants
Marburgvirus
Antioxidant Response Elements
Ebolavirus
Proteins
45 Citations (Scopus)

Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody

Geisbert, T., Mire, C., Geisbert, J. B., Chan, Y. P., Agans, K. N., Feldmann, F., Fenton, K. A., Zhu, Z., Dimitrov, D. S., Scott, D. P., Bossart, K. N., Feldmann, H. & Broder, C. C., Jun 25 2014, In : Science Translational Medicine. 6, 242, 242ra82.

Research output: Contribution to journalArticle

Nipah Virus
Virus Diseases
Primates
Monoclonal Antibodies
Cercopithecus aethiops
2 Citations (Scopus)

Vaccines and antivirals for filoviruses

Mire, C. & Geisbert, T., Jan 1 2014, Biology and Pathogenesis of Rhabdo- and Filoviruses. World Scientific Publishing Co., p. 587-620 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Marburgvirus
Antiviral Agents
Vaccines
Ebolavirus
Primates
2 Citations (Scopus)

Viral-vectored vaccines to control pathogenic filoviruses

Mire, C. & Geisbert, T., Jul 1 2014, Novel Technologies for Vaccine Development. Springer-Verlag Wien, Vol. 9783709118184. p. 33-60 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Viral Vaccines
Marburgvirus
Vaccines
Ebolavirus
Primates
2013
99 Citations (Scopus)

Mutual antagonism between the ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome

Luthra, P., Ramanan, P., Mire, C., Weisend, C., Tsuda, Y., Yen, B., Liu, G., Leung, D. W., Geisbert, T., Ebihara, H., Amarasinghe, G. K. & Basler, C. F., Jul 17 2013, In : Cell Host and Microbe. 14, 1, p. 74-84 11 p.

Research output: Contribution to journalArticle

Ebolavirus
Viral RNA
Ebola Hemorrhagic Fever
Pattern Recognition Receptors
Virus Replication
33 Citations (Scopus)

Single injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease

Mire, C., Versteeg, K. M., Cross, R., Agans, K. N., Fenton, K. A., Whitt, M. A. & Geisbert, T., Dec 13 2013, In : Virology Journal. 10, 353.

Research output: Contribution to journalArticle

Nipah Virus
Ferrets
Vesicular Stomatitis
Virus Diseases
Vaccines
52 Citations (Scopus)

Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus

Mire, C., Geisbert, J. B., Marzi, A., Agans, K. N., Feldmann, H. & Geisbert, T., 2013, In : PLoS Neglected Tropical Diseases. 7, 12, e2600.

Research output: Contribution to journalArticle

Ebolavirus
Vesicular Stomatitis
Primates
Vaccines
Viruses
2012
62 Citations (Scopus)

Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates

Mire, C., Miller, A. D., Carville, A., Westmoreland, S. V., Geisbert, J. B., Mansfield, K. G., Feldmann, H., Hensley, L. E. & Geisbert, T., Mar 2012, In : PLoS Neglected Tropical Diseases. 6, 3, e1567.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Primates
Glycoproteins
Vaccines
Viruses
2011
10 Citations (Scopus)

The protease-sensitive loop of the vesicular stomatitis virus matrix protein is involved in virus assembly and protein translation

Mire, C. & Whitt, M. A., Jul 20 2011, In : Virology. 416, 1-2, p. 16-25 10 p.

Research output: Contribution to journalArticle

Virus Assembly
Vesicular Stomatitis
Protein Biosynthesis
Peptide Hydrolases
Encephalomyocarditis virus
18 Citations (Scopus)

Utilization of fluorescently-labeled tetracysteine-tagged proteins to study virus entry by live cell microscopy

Whitt, M. A. & Mire, C., Oct 2011, In : Methods. 55, 2, p. 127-136 10 p.

Research output: Contribution to journalArticle

Virus Internalization
Viruses
Microscopy
Microscopic examination
Viral Proteins
2010
35 Citations (Scopus)

A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating

Mire, C., White, J. M. & Whitt, M. A., Jul 2010, In : PLoS Pathogens. 6, 7, p. 1-15 15 p., e1000994.

Research output: Contribution to journalArticle

Virus Uncoating
Spatio-Temporal Analysis
Vesicular Stomatitis
Protein Transport
Microtubules

A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating.

Mire, C. E., White, J. M. & Whitt, M. A., 2010, In : PLoS Pathogens. 6, 7, e1000994.

Research output: Contribution to journalArticle

Virus Uncoating
Spatio-Temporal Analysis
Vesicular Stomatitis
Protein Transport
Microtubules
2009
26 Citations (Scopus)

Glycoprotein-dependent acidification of vesicular stomatitis virus enhances release of matrix protein

Mire, C., Dube, D., Delos, S. E., White, J. M. & Whitt, M. A., Dec 2009, In : Journal of Virology. 83, 23, p. 12139-12150 12 p.

Research output: Contribution to journalArticle

Virus Release
Vesiculovirus
Vesicular Stomatitis
acidification
glycoproteins
2004
49 Citations (Scopus)

Lead Precipitation by Vibrio harveyi: Evidence for Novel Quorum-Sensing Interactions

Mire, C., Tourjee, J. A., O'Brien, W. F., Ramanujachary, K. V. & Hecht, G. B., Feb 2004, In : Applied and Environmental Microbiology. 70, 2, p. 855-864 10 p.

Research output: Contribution to journalArticle

Vibrio harveyi
Quorum Sensing
quorum sensing
Vibrio
mutants