Chad Mire, PhD

  • 1614 Citations
  • 25 h-Index
20042020

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2019

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

Bornholdt, Z. A., Herbert, A. S., Mire, C., He, S., Cross, R., Wec, A. Z., Abelson, D. M., Geisbert, J. B., James, R. M., Rahim, M. N., Zhu, W., Borisevich, V., Banadyga, L., Gunn, B. M., Agans, K. N., Wirchnianski, A. S., Goodwin, E., Tierney, K., Shestowsky, W. S., Bohorov, O. & 13 others, Bohorova, N., Velasco, J., Ailor, E., Kim, D., Pauly, M. H., Whaley, K. J., Alter, G., Walker, L. M., Chandran, K., Zeitlin, L., Qiu, X., Geisbert, T. & Dye, J. M., Jan 9 2019, In : Cell Host and Microbe. 25, 1, p. 49-58.e5

Research output: Contribution to journalArticle

13 Scopus citations

Current Ebola Virus Vaccine Progress

Marzi, A. & Mire, C., Jan 1 2019, (Accepted/In press) In : BioDrugs.

Research output: Contribution to journalArticle

7 Scopus citations

Use of Single-Injection Recombinant Vesicular Stomatitis Virus Vaccine to Protect Nonhuman Primates Against Lethal Nipah Virus Disease

Mire, C., Geisbert, J. B., Agans, K. N., Versteeg, K. M., Deer, D. J., Satterfield, B. A., Fenton, K. A. & Geisbert, T., Jun 1 2019, In : Emerging infectious diseases. 25, 6, p. 1144-1152 9 p.

Research output: Contribution to journalArticle

Open Access

Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever

Rodriguez, S., Cross, R., Fenton, K. A., Bente, D., Mire, C. & Geisbert, T., Dec 1 2019, In : Scientific reports. 9, 1, 7755.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2018
10 Scopus citations

Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates

Gilchuk, P., Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Cross, R., Slaughter, J. C., Flyak, A. I., Mani, J., Pauly, M. H., Velasco, J., Whaley, K. J., Zeitlin, L., Geisbert, T. & Crowe, J. E., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S565-S573

Research output: Contribution to journalArticle

1 Scopus citations

Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret (Mustela putorius furo)

Cross, R., Mire, C., Agans, K. N., Borisevich, V., Fenton, K. A. & Geisbert, T., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S448-S452

Research output: Contribution to journalArticle

6 Scopus citations
2017
8 Scopus citations

Disposable cartridge platform for rapid detection of viral hemorrhagic fever viruses

Scherr, S. M., Freedman, D. S., Agans, K. N., Rosca, A., Carter, E., Kuroda, M., Fawcett, H. E., Mire, C., Geisbert, T., Ünlü, M. S. & Connor, J. H., 2017, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 17, 5, p. 917-925 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses

Daaboul, G. G., Freedman, D. S., Scherr, S. M., Carter, E., Rosca, A., Bernstein, D., Mire, C., Agans, K. N., Hoenen, T., Geisbert, T., Selim Ünlü, M. & Connor, J. H., Jun 1 2017, In : PLoS One. 12, 6, e0179728.

Research output: Contribution to journalArticle

5 Scopus citations

Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants

Versteeg, K., Menicucci, A. R., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jeske, D., Messaoudi, I. & Geisbert, T., Dec 1 2017, In : Scientific Reports. 7, 1, 9730.

Research output: Contribution to journalArticle

11 Scopus citations
14 Scopus citations
2016

Inhibition of the host antiviral response by Nipah virus: Current understanding and future perspectives

Satterfield, B. A., Geisbert, T. & Mire, C., May 1 2016, In : Future Virology. 11, 5, p. 331-344 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

Isolation and characterization of a novel gammaherpesvirus from a microbat cell line

Shabman, R. S., Shrivastava, S., Tsibane, T., Attie, O., Jayaprakash, A., Mire, C., Dilley, K. E., Puri, V., Stockwell, T. B., Geisbert, T., Sachidanandam, R. & Basler, C. F., Jan 1 2016, In : mSphere. 1, 1, e00070-15.

Research output: Contribution to journalArticle

9 Scopus citations

Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly from Blood

Benzine, J. W., Brown, K. M., Agans, K. N., Godiska, R., Mire, C., Gowda, K., Converse, B., Geisbert, T., Mead, D. A. & Chander, Y., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S234-S242

Research output: Contribution to journalArticle

14 Scopus citations

Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus

Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Fenton, K. A. & Geisbert, T., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S263-S267

Research output: Contribution to journalArticle

13 Scopus citations

Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy

Mire, C., Satterfield, B. A., Geisbert, J. B., Agans, K. N., Borisevich, V., Yan, L., Chan, Y. P., Cross, R., Fenton, K. A., Broder, C. C. & Geisbert, T., Aug 3 2016, In : Scientific Reports. 6, 30916.

Research output: Contribution to journalArticle

27 Scopus citations

The domestic ferret (mustela putorius furo) as a lethal infection model for 3 species of ebolavirus

Cross, R., Mire, C., Borisevich, V., Geisbert, J. B., Fenton, K. A. & Geisbert, T., Aug 15 2016, In : Journal of Infectious Diseases. 214, 4, p. 565-569 5 p.

Research output: Contribution to journalArticle

38 Scopus citations

The synthetic antiviral drug arbidol inhibits globally prevalent pathogenic viruses

Pécheur, E. I., Borisevich, V., Halfmann, P., Morrey, J. D., Smee, D. F., Prichard, M., Mire, C., Kawaoka, Y., Geisbert, T. & Polyak, S. J., 2016, In : Journal of Virology. 90, 6, p. 3086-3092 7 p.

Research output: Contribution to journalArticle

25 Scopus citations
20 Scopus citations
2015

Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses

Meyer, M., Garron, T., Lubaki, N. M., Mire, C., Fenton, K. A., Klages, C., Olinger, G. G., Geisbert, T., Collins, P. L. & Bukreyev, A., Aug 3 2015, In : Journal of Clinical Investigation. 125, 8, p. 3241-3255 15 p.

Research output: Contribution to journalArticle

40 Scopus citations

Analytical performance characteristics of the cepheid GeneXpert Ebola Assay for the detection of Ebola virus

Pinsky, B. A., Sahoo, M. K., Sandlund, J., Kleman, M., Kulkarni, M., Grufman, P., Nygren, M., Kwiatkowski, R., Baron, E. J., Tenover, F., Denison, B., Higuchi, R., Van Atta, R., Beer, N. R., Carrillo, A. C., Naraghi-Arani, P., Mire, C., Ranadheera, C., Grolla, A., Lagerqvist, N. & 1 others, Persing, D. H., Nov 1 2015, In : PLoS One. 10, 11, e0142216.

Research output: Contribution to journalArticle

28 Scopus citations

A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and Macaques against Challenge with Geographically and Genetically Distinct Lassa Viruses

Safronetz, D., Mire, C., Rosenke, K., Feldmann, F., Haddock, E., Geisbert, T. & Feldmann, H., Apr 17 2015, In : PLoS Neglected Tropical Diseases. 9, 4, e0003736.

Research output: Contribution to journalArticle

42 Scopus citations

A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs

Mire, C., Geisbert, J. B., Versteeg, K. M., Mamaeva, N., Agans, K. N., Geisbert, T. & Connor, J. H., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S384-S388

Research output: Contribution to journalArticle

20 Scopus citations
24 Scopus citations

Current and emerging strategies for the diagnosis, prevention and treatment of Lassa fever

Hartnett, J. N., Boisen, M. L., Oottamasathien, D., Jones, A. B., Millett, M. M., Nelson, D. S., Muncy, I. J., Goba, A., Momoh, M., Fullah, M., Mire, C., Geisbert, J. B., Geisbert, T., Holton, D. L., Rouelle, J. A., Kannadka, C. B., Reyna, A. A., Moses, L. M., Khan, S. H., Gevao, S. M. & 6 others, Grant, D. S., Robinson, J. E., Happi, C., Pitts, K. R., Garry, R. F. & Branco, L. M., May 1 2015, In : Future Virology. 10, 5, p. 559-584 26 p.

Research output: Contribution to journalArticle

9 Scopus citations

Erratum: Analytical performance characteristics of the cepheid genexpert ebola assay for the detection of ebola virus (PLoS One)

Pinsky, B. A., Sahoo, M. K., Sandlund, J., Kleman, M., Kulkarni, M., Grufman, P., Nygren, M., Kwiatkowski, R., Baron, E. J., Tenover, F., Denison, B., Higuchi, R., Van Atta, R., Beer, N. R., Carrillo, A. C., Naraghi-Arani, P., Mire, C., Ranadheera, C., Grolla, A., Lagerqvist, N. & 1 others, Persing, D. H., Dec 1 2015, In : PLoS One. 10, 12, 0145896.

Research output: Contribution to journalArticle

3 Scopus citations

Modeling the Disease Course of Zaire ebolavirus Infection in the Outbred Guinea Pig

Cross, R., Fenton, K. A., Geisbert, J. B., Mire, C. & Geisbert, T., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S305-S315

Research output: Contribution to journalArticle

28 Scopus citations

Single-dose attenuated Vesiculovax vaccines protect primates against Ebola Makona virus

Mire, C., Matassov, D., Geisbert, J. B., Latham, T. E., Agans, K. N., Xu, R., Ota-Setlik, A., Egan, M. A., Fenton, K. A., Clarke, D. K., Eldridge, J. H. & Geisbert, T., Apr 30 2015, In : Nature. 520, 7549, p. 688-691 4 p.

Research output: Contribution to journalArticle

64 Scopus citations
21 Scopus citations

Vaccination with a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge with a Lethal Dose of Ebola Virus

Matassov, D., Marzi, A., Latham, T., Xu, R., Ota-Setlik, A., Feldmann, F., Geisbert, J. B., Mire, C., Hamm, S., Nowak, B., Egan, M. A., Geisbert, T., Eldridge, J. H., Feldmann, H. & Clarke, D. K., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S443-S451

Research output: Contribution to journalArticle

30 Scopus citations
2014

A recombinant Hendra Virus G glycoprotein subunit vaccine protects nonhuman primates against hendra virus challenge

Mire, C., Geisbert, J. B., Agans, K. N., Feng, Y. R., Fenton, K. A., Bossart, K. N., Yan, L., Chan, Y. P., Broder, C. C. & Geisbert, T., 2014, In : Journal of Virology. 88, 9, p. 4624-4631 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells

Shabman, R. S., Jabado, O. J., Mire, C. E., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. W. & Basler, C. F., 2014, In : mBio. 5, 6, p. e02011

Research output: Contribution to journalArticle

41 Scopus citations