Chad Mire, PhD

  • 1518 Citations
  • 24 h-Index
20042020
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Research Output 2004 2019

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Article
2004
45 Citations (Scopus)

Lead Precipitation by Vibrio harveyi: Evidence for Novel Quorum-Sensing Interactions

Mire, C., Tourjee, J. A., O'Brien, W. F., Ramanujachary, K. V. & Hecht, G. B., Feb 2004, In : Applied and Environmental Microbiology. 70, 2, p. 855-864 10 p.

Research output: Contribution to journalArticle

Vibrio harveyi
Quorum Sensing
quorum sensing
Vibrio
mutants
2009
26 Citations (Scopus)

Glycoprotein-dependent acidification of vesicular stomatitis virus enhances release of matrix protein

Mire, C., Dube, D., Delos, S. E., White, J. M. & Whitt, M. A., Dec 2009, In : Journal of Virology. 83, 23, p. 12139-12150 12 p.

Research output: Contribution to journalArticle

Virus Release
Vesiculovirus
Vesicular Stomatitis
acidification
glycoproteins
2010
30 Citations (Scopus)

A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating

Mire, C., White, J. M. & Whitt, M. A., Jul 2010, In : PLoS Pathogens. 6, 7, p. 1-15 15 p., e1000994.

Research output: Contribution to journalArticle

Virus Uncoating
Spatio-Temporal Analysis
Vesicular Stomatitis
Protein Transport
Microtubules

A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating.

Mire, C. E., White, J. M. & Whitt, M. A., 2010, In : PLoS Pathogens. 6, 7, e1000994.

Research output: Contribution to journalArticle

Virus Uncoating
Spatio-Temporal Analysis
Vesicular Stomatitis
Protein Transport
Microtubules
2011
10 Citations (Scopus)

The protease-sensitive loop of the vesicular stomatitis virus matrix protein is involved in virus assembly and protein translation

Mire, C. & Whitt, M. A., Jul 20 2011, In : Virology. 416, 1-2, p. 16-25 10 p.

Research output: Contribution to journalArticle

Virus Assembly
Vesicular Stomatitis
Protein Biosynthesis
Peptide Hydrolases
Encephalomyocarditis virus
18 Citations (Scopus)

Utilization of fluorescently-labeled tetracysteine-tagged proteins to study virus entry by live cell microscopy

Whitt, M. A. & Mire, C., Oct 2011, In : Methods. 55, 2, p. 127-136 10 p.

Research output: Contribution to journalArticle

Virus Internalization
Viruses
Microscopy
Microscopic examination
Viral Proteins
2012
61 Citations (Scopus)

Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates

Mire, C., Miller, A. D., Carville, A., Westmoreland, S. V., Geisbert, J. B., Mansfield, K. G., Feldmann, H., Hensley, L. E. & Geisbert, T., Mar 2012, In : PLoS Neglected Tropical Diseases. 6, 3, e1567.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Primates
Glycoproteins
Vaccines
Viruses
2013
98 Citations (Scopus)

Mutual antagonism between the ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome

Luthra, P., Ramanan, P., Mire, C., Weisend, C., Tsuda, Y., Yen, B., Liu, G., Leung, D. W., Geisbert, T., Ebihara, H., Amarasinghe, G. K. & Basler, C. F., Jul 17 2013, In : Cell Host and Microbe. 14, 1, p. 74-84 11 p.

Research output: Contribution to journalArticle

Ebolavirus
Viral RNA
Ebola Hemorrhagic Fever
Pattern Recognition Receptors
Virus Replication
31 Citations (Scopus)

Single injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease

Mire, C., Versteeg, K. M., Cross, R., Agans, K. N., Fenton, K. A., Whitt, M. A. & Geisbert, T., Dec 13 2013, In : Virology Journal. 10, 353.

Research output: Contribution to journalArticle

Nipah Virus
Ferrets
Vesicular Stomatitis
Virus Diseases
Vaccines
51 Citations (Scopus)

Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus

Mire, C., Geisbert, J. B., Marzi, A., Agans, K. N., Feldmann, H. & Geisbert, T., 2013, In : PLoS Neglected Tropical Diseases. 7, 12, e2600.

Research output: Contribution to journalArticle

Ebolavirus
Vesicular Stomatitis
Primates
Vaccines
Viruses
2014
17 Citations (Scopus)

A recombinant Hendra Virus G glycoprotein subunit vaccine protects nonhuman primates against hendra virus challenge

Mire, C., Geisbert, J. B., Agans, K. N., Feng, Y. R., Fenton, K. A., Bossart, K. N., Yan, L., Chan, Y. P., Broder, C. C. & Geisbert, T., 2014, In : Journal of Virology. 88, 9, p. 4624-4631 8 p.

Research output: Contribution to journalArticle

Hendra Virus
Hendra virus
Subunit Vaccines
subunit vaccines
Primates

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells

Shabman, R. S., Jabado, O. J., Mire, C. E., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. W. & Basler, C. F., 2014, In : mBio. 5, 6, p. e02011

Research output: Contribution to journalArticle

Marburgvirus
Ebolavirus
High-Throughput Nucleotide Sequencing
RNA
Messenger RNA
40 Citations (Scopus)

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAS in infected cells

Shabman, R. S., Jabado, O. J., Mire, C., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. & Basler, C. F., Sep 25 2014, In : mBio. 5, 6, e02011-14.

Research output: Contribution to journalArticle

Marburgvirus
Ebolavirus
High-Throughput Nucleotide Sequencing
Messenger RNA
Nucleoproteins
40 Citations (Scopus)

Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates

Mire, C., Geisbert, J. B., Agans, K. N., Satterfield, B. A., Versteeg, K. M., Fritz, E. A., Feldmann, H., Hensley, L. E. & Geisbert, T., Apr 23 2014, In : PLoS One. 9, 4, e94355.

Research output: Contribution to journalArticle

Marburg virus
Marburgvirus
Vesiculovirus
Vesicular Stomatitis
Filoviridae
44 Citations (Scopus)

Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA

Thi, E. P., Mire, C., Ursic-Bedoya, R., Geisbert, J. B., Lee, A. C. H., Agans, K. N., Robbins, M., Deer, D. J., Fenton, K. A., MacLachlan, I. & Geisbert, T., Aug 20 2014, In : Science Translational Medicine. 6, 250, 250ra116.

Research output: Contribution to journalArticle

Marburgvirus
Virus Diseases
Angola
Primates
Small Interfering RNA
27 Citations (Scopus)

Protection against lethal marburg virus infection mediated by lipid encapsulated small interfering RNA

Ursic-Bedoya, R., Mire, C., Robbins, M., Geisbert, J. B., Judge, A., MacLachlan, I. & Geisbert, T., Feb 15 2014, In : Journal of Infectious Diseases. 209, 4, p. 562-570 9 p.

Research output: Contribution to journalArticle

Marburgvirus
Virus Diseases
Small Interfering RNA
Lipids
Angola
53 Citations (Scopus)

The Marburg Virus VP24 Protein Interacts with Keap1 to Activate the Cytoprotective Antioxidant Response Pathway

Edwards, M. R., Johnson, B., Mire, C., Xu, W., Shabman, R. S., Speller, L. N., Leung, D. W., Geisbert, T., Amarasinghe, G. K. & Basler, C. F., Mar 27 2014, In : Cell Reports. 6, 6, p. 1017-1025 9 p.

Research output: Contribution to journalArticle

Antioxidants
Marburgvirus
Antioxidant Response Elements
Ebolavirus
Proteins
42 Citations (Scopus)

Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody

Geisbert, T., Mire, C., Geisbert, J. B., Chan, Y. P., Agans, K. N., Feldmann, F., Fenton, K. A., Zhu, Z., Dimitrov, D. S., Scott, D. P., Bossart, K. N., Feldmann, H. & Broder, C. C., Jun 25 2014, In : Science Translational Medicine. 6, 242, 242ra82.

Research output: Contribution to journalArticle

Nipah Virus
Virus Diseases
Primates
Monoclonal Antibodies
Cercopithecus aethiops
2015
40 Citations (Scopus)

Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses

Meyer, M., Garron, T., Lubaki, N. M., Mire, C., Fenton, K. A., Klages, C., Olinger, G. G., Geisbert, T., Collins, P. L. & Bukreyev, A., Aug 3 2015, In : Journal of Clinical Investigation. 125, 8, p. 3241-3255 15 p.

Research output: Contribution to journalArticle

Ebola Vaccines
Ebolavirus
Primates
Vaccines
T-Lymphocytes
26 Citations (Scopus)

Analytical performance characteristics of the cepheid GeneXpert Ebola Assay for the detection of Ebola virus

Pinsky, B. A., Sahoo, M. K., Sandlund, J., Kleman, M., Kulkarni, M., Grufman, P., Nygren, M., Kwiatkowski, R., Baron, E. J., Tenover, F., Denison, B., Higuchi, R., Van Atta, R., Beer, N. R., Carrillo, A. C., Naraghi-Arani, P., Mire, C., Ranadheera, C., Grolla, A., Lagerqvist, N. & 1 others, Persing, D. H., Nov 1 2015, In : PLoS One. 10, 11, e0142216.

Research output: Contribution to journalArticle

Ebolavirus
Viruses
Assays
assays
Virus Inactivation
40 Citations (Scopus)

A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and Macaques against Challenge with Geographically and Genetically Distinct Lassa Viruses

Safronetz, D., Mire, C., Rosenke, K., Feldmann, F., Haddock, E., Geisbert, T. & Feldmann, H., Apr 17 2015, In : PLoS Neglected Tropical Diseases. 9, 4, e0003736.

Research output: Contribution to journalArticle

Lassa Fever
Lassa virus
Vesicular Stomatitis
Macaca
Guinea Pigs
20 Citations (Scopus)

A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs

Mire, C., Geisbert, J. B., Versteeg, K. M., Mamaeva, N., Agans, K. N., Geisbert, T. & Connor, J. H., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S384-S388

Research output: Contribution to journalArticle

Ebolavirus
Guinea Pigs
Marburgvirus
Vaccines
Democratic Republic of the Congo
23 Citations (Scopus)

Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model

Cross, R., Fenton, K. A., Geisbert, J. B., Ebihara, H., Mire, C. & Geisbert, T., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S258-S270

Research output: Contribution to journalArticle

Marburgvirus
Angola
Guinea Pigs
Virus Diseases
Viremia
9 Citations (Scopus)

Current and emerging strategies for the diagnosis, prevention and treatment of Lassa fever

Hartnett, J. N., Boisen, M. L., Oottamasathien, D., Jones, A. B., Millett, M. M., Nelson, D. S., Muncy, I. J., Goba, A., Momoh, M., Fullah, M., Mire, C., Geisbert, J. B., Geisbert, T., Holton, D. L., Rouelle, J. A., Kannadka, C. B., Reyna, A. A., Moses, L. M., Khan, S. H., Gevao, S. M. & 6 others, Grant, D. S., Robinson, J. E., Happi, C., Pitts, K. R., Garry, R. F. & Branco, L. M., May 1 2015, In : Future Virology. 10, 5, p. 559-584 26 p.

Research output: Contribution to journalArticle

Lassa Fever
Lassa virus
Western Africa
Bioterrorism
Virus Diseases
2 Citations (Scopus)

Erratum: Analytical performance characteristics of the cepheid genexpert ebola assay for the detection of ebola virus (PLoS One)

Pinsky, B. A., Sahoo, M. K., Sandlund, J., Kleman, M., Kulkarni, M., Grufman, P., Nygren, M., Kwiatkowski, R., Baron, E. J., Tenover, F., Denison, B., Higuchi, R., Van Atta, R., Beer, N. R., Carrillo, A. C., Naraghi-Arani, P., Mire, C., Ranadheera, C., Grolla, A., Lagerqvist, N. & 1 others, Persing, D. H., Dec 1 2015, In : PLoS One. 10, 12, 0145896.

Research output: Contribution to journalArticle

135 Citations (Scopus)

Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates

Thi, E. P., Mire, C., Lee, A. C. H., Geisbert, J. B., Zhou, J. Z., Agans, K. N., Snead, N. M., Deer, D. J., Barnard, T. R., Fenton, K. A., Maclachlan, I. & Geisbert, T., May 21 2015, In : Nature. 521, 7552, p. 362-365 4 p.

Research output: Contribution to journalArticle

Ebolavirus
Nanoparticles
Primates
Small Interfering RNA
Disease Outbreaks
28 Citations (Scopus)

Modeling the Disease Course of Zaire ebolavirus Infection in the Outbred Guinea Pig

Cross, R., Fenton, K. A., Geisbert, J. B., Mire, C. & Geisbert, T., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S305-S315

Research output: Contribution to journalArticle

Ebolavirus
Democratic Republic of the Congo
Guinea Pigs
Primates
Ebola Hemorrhagic Fever
64 Citations (Scopus)

Single-dose attenuated Vesiculovax vaccines protect primates against Ebola Makona virus

Mire, C., Matassov, D., Geisbert, J. B., Latham, T. E., Agans, K. N., Xu, R., Ota-Setlik, A., Egan, M. A., Fenton, K. A., Clarke, D. K., Eldridge, J. H. & Geisbert, T., Apr 30 2015, In : Nature. 520, 7549, p. 688-691 4 p.

Research output: Contribution to journalArticle

Ebolavirus
Attenuated Vaccines
Democratic Republic of the Congo
Primates
Vaccines
19 Citations (Scopus)

The immunomodulating v and W proteins of Nipah virus determine disease course

Satterfield, B. A., Cross, R., Fenton, K. A., Agans, K. N., Basler, C. F., Geisbert, T. & Mire, C., Jun 24 2015, In : Nature Communications. 6, 7483.

Research output: Contribution to journalArticle

viruses
Virus Diseases
Nipah Virus
Viruses
proteins
28 Citations (Scopus)

Vaccination with a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge with a Lethal Dose of Ebola Virus

Matassov, D., Marzi, A., Latham, T., Xu, R., Ota-Setlik, A., Feldmann, F., Geisbert, J. B., Mire, C., Hamm, S., Nowak, B., Egan, M. A., Geisbert, T., Eldridge, J. H., Feldmann, H. & Clarke, D. K., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S443-S451

Research output: Contribution to journalArticle

Ebolavirus
Vesicular Stomatitis
Vaccination
Viruses
Glycoproteins
2016
33 Citations (Scopus)

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins

Edwards, M. R., Liu, G., Mire, C., Sureshchandra, S., Luthra, P., Yen, B., Shabman, R. S., Leung, D. W., Messaoudi, I., Geisbert, T., Amarasinghe, G. K. & Basler, C. F., Feb 23 2016, In : Cell Reports. 14, 7, p. 1632-1640 9 p.

Research output: Contribution to journalArticle

Marburgvirus
Viruses
Interferons
Ebolavirus
RNA
2 Citations (Scopus)

Inhibition of the host antiviral response by Nipah virus: Current understanding and future perspectives

Satterfield, B. A., Geisbert, T. & Mire, C., May 1 2016, In : Future Virology. 11, 5, p. 331-344 14 p.

Research output: Contribution to journalArticle

Nipah Virus
Antiviral Agents
Viral Proteins
Acute Disease
Encephalitis
8 Citations (Scopus)

Isolation and characterization of a novel gammaherpesvirus from a microbat cell line

Shabman, R. S., Shrivastava, S., Tsibane, T., Attie, O., Jayaprakash, A., Mire, C., Dilley, K. E., Puri, V., Stockwell, T. B., Geisbert, T., Sachidanandam, R. & Basler, C. F., Jan 1 2016, In : mSphere. 1, 1, e00070-15.

Research output: Contribution to journalArticle

Rhadinovirus
Open Reading Frames
High-Throughput Nucleotide Sequencing
Cell Line
Vero Cells
13 Citations (Scopus)

Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly from Blood

Benzine, J. W., Brown, K. M., Agans, K. N., Godiska, R., Mire, C., Gowda, K., Converse, B., Geisbert, T., Mead, D. A. & Chander, Y., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S234-S242

Research output: Contribution to journalArticle

Point-of-Care Systems
Ebolavirus
Molecular Pathology
Routine Diagnostic Tests
RNA-Directed DNA Polymerase
11 Citations (Scopus)

Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus

Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Fenton, K. A. & Geisbert, T., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S263-S267

Research output: Contribution to journalArticle

Ebolavirus
Primates
Ebola Hemorrhagic Fever
Aerosols
Infection
17 Citations (Scopus)

Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates

Mire, C., Geisbert, J. B., Agans, K. N., Thi, E. P., Lee, A. C. H., Fenton, K. A. & Geisbert, T., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S367-S374

Research output: Contribution to journalArticle

Ebola Hemorrhagic Fever
Ebolavirus
Passive Immunization
Primates
Democratic Republic of the Congo
24 Citations (Scopus)

Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy

Mire, C., Satterfield, B. A., Geisbert, J. B., Agans, K. N., Borisevich, V., Yan, L., Chan, Y. P., Cross, R., Fenton, K. A., Broder, C. C. & Geisbert, T., Aug 3 2016, In : Scientific Reports. 6, 30916.

Research output: Contribution to journalArticle

Nipah Virus
Bangladesh
Malaysia
Primates
Antibodies
18 Citations (Scopus)

Polyamines and hypusination are required for ebolavirus gene expression and replication

Olsen, M. E., Filone, C. M., Rozelle, D., Mire, C., Agans, K. N., Hensley, L. & Connor, J. H., Jul 1 2016, In : mBio. 7, 4, e00882-16.

Research output: Contribution to journalArticle

Ebolavirus
Polyamines
Eukaryotic Initiation Factors
Gene Expression
Viral Structures
13 Citations (Scopus)

Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA

Thi, E. P., Lee, A. C. H., Geisbert, J. B., Ursic-Bedoya, R., Agans, K. N., Robbins, M., Deer, D. J., Fenton, K. A., Kondratowicz, A. S., MacLachlan, I., Geisbert, T. & Mire, C., Aug 22 2016, In : Nature Microbiology. 1, 16142.

Research output: Contribution to journalArticle

Ebolavirus
Sudan
Primates
Small Interfering RNA
Nanoparticles
20 Citations (Scopus)

Targeting innate immunity for antiviral therapy through small molecule agonists of the RLR pathway

Pattabhi, S., Wilkins, C. R., Dong, R., Knoll, M. L., Posakony, J., Kaiser, S., Mire, C., Wang, M. L., Ireton, R. C., Geisbert, T., Bedard, K. M., Iadonato, S. P., Loo, Y. M. & Gale, M., 2016, In : Journal of Virology. 90, 5, p. 2372-2387 16 p.

Research output: Contribution to journalArticle

Interferon Regulatory Factor-3
Innate Immunity
agonists
Antiviral Agents
viruses
37 Citations (Scopus)

The domestic ferret (mustela putorius furo) as a lethal infection model for 3 species of ebolavirus

Cross, R., Mire, C., Borisevich, V., Geisbert, J. B., Fenton, K. A. & Geisbert, T., Aug 15 2016, In : Journal of Infectious Diseases. 214, 4, p. 565-569 5 p.

Research output: Contribution to journalArticle

Ebolavirus
Ferrets
Animal Models
Primate Diseases
Filoviridae
24 Citations (Scopus)

The synthetic antiviral drug arbidol inhibits globally prevalent pathogenic viruses

Pécheur, E. I., Borisevich, V., Halfmann, P., Morrey, J. D., Smee, D. F., Prichard, M., Mire, C., Kawaoka, Y., Geisbert, T. & Polyak, S. J., 2016, In : Journal of Virology. 90, 6, p. 3086-3092 7 p.

Research output: Contribution to journalArticle

antiviral agents
Antiviral Agents
Zaire Ebola virus
Viruses
viruses
19 Citations (Scopus)

Treatment of Lassa virus infection in outbred guinea pigs with first-in-class human monoclonal antibodies

Cross, R., Mire, C., Branco, L. M., Geisbert, J. B., Rowland, M. M., Heinrich, M. L., Goba, A., Momoh, M., Grant, D. S., Fullah, M., Khan, S. H., Robinson, J. E., Geisbert, T. & Garry, R. F., Sep 1 2016, In : Antiviral Research. 133, p. 218-222 5 p.

Research output: Contribution to journalArticle

Lassa virus
Virus Diseases
Guinea Pigs
Monoclonal Antibodies
Lassa Fever
2017
7 Citations (Scopus)

Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo

Warfield, K. L., Warren, T. K., Qiu, X., Wells, J., Mire, C., Geisbert, J. B., Stuthman, K. S., Garza, N. L., Van Tongeren, S. A., Shurtleff, A. C., Agans, K. N., Wong, G., Callahan, M. V., Geisbert, T., Klose, B., Ramstedt, U. & Treston, A. M., Feb 1 2017, In : Antiviral Research. 138, p. 22-31 10 p.

Research output: Contribution to journalArticle

Marburgvirus
Antiviral Agents
Infection
Primates
Human Influenza
8 Citations (Scopus)

Disposable cartridge platform for rapid detection of viral hemorrhagic fever viruses

Scherr, S. M., Freedman, D. S., Agans, K. N., Rosca, A., Carter, E., Kuroda, M., Fawcett, H. E., Mire, C., Geisbert, T., Ünlü, M. S. & Connor, J. H., 2017, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 17, 5, p. 917-925 9 p.

Research output: Contribution to journalArticle

Viral Hemorrhagic Fevers
Viruses
Virion
Virus Attachment
Imaging techniques
5 Citations (Scopus)

Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses

Daaboul, G. G., Freedman, D. S., Scherr, S. M., Carter, E., Rosca, A., Bernstein, D., Mire, C., Agans, K. N., Hoenen, T., Geisbert, T., Selim Ünlü, M. & Connor, J. H., Jun 1 2017, In : PLoS One. 12, 6, e0179728.

Research output: Contribution to journalArticle

Zika virus
Ebolavirus
Viruses
virion
Virion
26 Citations (Scopus)

Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever

Mire, C., Cross, R., Geisbert, J. B., Borisevich, V., Agans, K. N., Deer, D. J., Heinrich, M. L., Rowland, M. M., Goba, A., Momoh, M., Boisen, M. L., Grant, D. S., Fullah, M., Khan, S. H., Fenton, K. A., Robinson, J. E., Branco, L. M., Garry, R. F. & Geisbert, T., Oct 1 2017, In : Nature Medicine. 23, 10, p. 1146-1149 4 p.

Research output: Contribution to journalArticle

Lassa Fever
Lassa virus
Western Africa
Macaca
Viruses
10 Citations (Scopus)

Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants

Versteeg, K., Menicucci, A. R., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jeske, D., Messaoudi, I. & Geisbert, T., Dec 1 2017, In : Scientific Reports. 7, 1, 9730.

Research output: Contribution to journalArticle

Ebolavirus
Democratic Republic of the Congo
Infection
Disease Progression
Genes
5 Citations (Scopus)

siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease

Thi, E. P., Mire, C., Lee, A. C. H., Geisbert, J. B., Ursic-Bedoya, R., Agans, K. N., Robbins, M., Deer, D. J., Cross, R., Kondratowicz, A. S., Fenton, K. A., MacLachlan, I. & Geisbert, T., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4437-4448 12 p.

Research output: Contribution to journalArticle

Marburg Virus Disease
Marburgvirus
Primates
Small Interfering RNA
Viruses
23 Citations (Scopus)

Therapeutic treatment of marburg and ravn virus infection in nonhuman primates with a human monoclonal antibody

Mire, C., Geisbert, J. B., Borisevich, V., Fenton, K. A., Agans, K. N., Flyak, A. I., Deer, D. J., Steinkellner, H., Bohorov, O., Bohorova, N., Goodman, C., Hiatt, A., Kim, D. H., Pauly, M. H., Velasco, J., Whaley, K. J., Crowe, J. E., Zeitlin, L. & Geisbert, T., Apr 5 2017, In : Science Translational Medicine. 9, 384, eaai8711.

Research output: Contribution to journalArticle

Marburgvirus
Virus Diseases
Primates
Monoclonal Antibodies
Ebola Hemorrhagic Fever