Chad Mire, PhD

  • 1518 Citations
  • 24 h-Index
20042020
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Research Output 2004 2019

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40 Citations (Scopus)

Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses

Meyer, M., Garron, T., Lubaki, N. M., Mire, C., Fenton, K. A., Klages, C., Olinger, G. G., Geisbert, T., Collins, P. L. & Bukreyev, A., Aug 3 2015, In : Journal of Clinical Investigation. 125, 8, p. 3241-3255 15 p.

Research output: Contribution to journalArticle

Ebola Vaccines
Ebolavirus
Primates
Vaccines
T-Lymphocytes
26 Citations (Scopus)

Analytical performance characteristics of the cepheid GeneXpert Ebola Assay for the detection of Ebola virus

Pinsky, B. A., Sahoo, M. K., Sandlund, J., Kleman, M., Kulkarni, M., Grufman, P., Nygren, M., Kwiatkowski, R., Baron, E. J., Tenover, F., Denison, B., Higuchi, R., Van Atta, R., Beer, N. R., Carrillo, A. C., Naraghi-Arani, P., Mire, C., Ranadheera, C., Grolla, A., Lagerqvist, N. & 1 others, Persing, D. H., Nov 1 2015, In : PLoS One. 10, 11, e0142216.

Research output: Contribution to journalArticle

Ebolavirus
Viruses
Assays
assays
Virus Inactivation

An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections

Dang, H. V., Chan, Y. P., Park, Y. J., Snijder, J., Da Silva, S. C., Vu, B., Yan, L., Feng, Y. R., Rockx, B., Geisbert, T. W., Mire, C. E., Broder, C. C. & Veesler, D., Oct 1 2019, In : Nature Structural and Molecular Biology. 26, 10, p. 980-987 8 p.

Research output: Contribution to journalArticle

Hendra Virus
Nipah Virus
Virus Diseases
Henipavirus
Glycoproteins

Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model

Satterfield, B. A., Borisevich, V., Foster, S. L., Rodriguez, S. E., Cross, R. W., Fenton, K. A., Agans, K. N., Basler, C. F., Geisbert, T. W. & Mire, C. E., Dec 1 2019, In : Scientific reports. 9, 1, 16710.

Research output: Contribution to journalArticle

Open Access
Nipah Virus
Ferrets
Virus Diseases
Mutation
Genes
9 Citations (Scopus)

A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates

Callendret, B., Vellinga, J., Wunderlich, K., Rodriguez, A., Steigerwald, R., Dirmeier, U., Cheminay, C., Volkmann, A., Brasel, T., Carrion, R., Giavedoni, L. D., Patterson, J. L., Mire, C., Geisbert, T., Hooper, J. W., Weijtens, M., Hartkoorn-Pasma, J., Custers, J., Pau, M. G., Schuitemaker, H. & 1 others, Zahn, R., Feb 1 2018, In : PLoS One. 13, 2, e0192312.

Research output: Contribution to journalArticle

Marburgvirus
Filoviridae
Ebolavirus
Viruses
Primates
17 Citations (Scopus)

A recombinant Hendra Virus G glycoprotein subunit vaccine protects nonhuman primates against hendra virus challenge

Mire, C., Geisbert, J. B., Agans, K. N., Feng, Y. R., Fenton, K. A., Bossart, K. N., Yan, L., Chan, Y. P., Broder, C. C. & Geisbert, T., 2014, In : Journal of Virology. 88, 9, p. 4624-4631 8 p.

Research output: Contribution to journalArticle

Hendra Virus
Hendra virus
Subunit Vaccines
subunit vaccines
Primates
40 Citations (Scopus)

A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and Macaques against Challenge with Geographically and Genetically Distinct Lassa Viruses

Safronetz, D., Mire, C., Rosenke, K., Feldmann, F., Haddock, E., Geisbert, T. & Feldmann, H., Apr 17 2015, In : PLoS Neglected Tropical Diseases. 9, 4, e0003736.

Research output: Contribution to journalArticle

Lassa Fever
Lassa virus
Vesicular Stomatitis
Macaca
Guinea Pigs
20 Citations (Scopus)

A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs

Mire, C., Geisbert, J. B., Versteeg, K. M., Mamaeva, N., Agans, K. N., Geisbert, T. & Connor, J. H., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S384-S388

Research output: Contribution to journalArticle

Ebolavirus
Guinea Pigs
Marburgvirus
Vaccines
Democratic Republic of the Congo
30 Citations (Scopus)

A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating

Mire, C., White, J. M. & Whitt, M. A., Jul 2010, In : PLoS Pathogens. 6, 7, p. 1-15 15 p., e1000994.

Research output: Contribution to journalArticle

Virus Uncoating
Spatio-Temporal Analysis
Vesicular Stomatitis
Protein Transport
Microtubules

A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating.

Mire, C. E., White, J. M. & Whitt, M. A., 2010, In : PLoS Pathogens. 6, 7, e1000994.

Research output: Contribution to journalArticle

Virus Uncoating
Spatio-Temporal Analysis
Vesicular Stomatitis
Protein Transport
Microtubules
7 Citations (Scopus)

Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo

Warfield, K. L., Warren, T. K., Qiu, X., Wells, J., Mire, C., Geisbert, J. B., Stuthman, K. S., Garza, N. L., Van Tongeren, S. A., Shurtleff, A. C., Agans, K. N., Wong, G., Callahan, M. V., Geisbert, T., Klose, B., Ramstedt, U. & Treston, A. M., Feb 1 2017, In : Antiviral Research. 138, p. 22-31 10 p.

Research output: Contribution to journalArticle

Marburgvirus
Antiviral Agents
Infection
Primates
Human Influenza
9 Citations (Scopus)

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

Bornholdt, Z. A., Herbert, A. S., Mire, C., He, S., Cross, R., Wec, A. Z., Abelson, D. M., Geisbert, J. B., James, R. M., Rahim, M. N., Zhu, W., Borisevich, V., Banadyga, L., Gunn, B. M., Agans, K. N., Wirchnianski, A. S., Goodwin, E., Tierney, K., Shestowsky, W. S., Bohorov, O. & 13 others, Bohorova, N., Velasco, J., Ailor, E., Kim, D., Pauly, M. H., Whaley, K. J., Alter, G., Walker, L. M., Chandran, K., Zeitlin, L., Qiu, X., Geisbert, T. & Dye, J. M., Jan 9 2019, In : Cell Host and Microbe. 25, 1, p. 49-58.e5

Research output: Contribution to journalArticle

Ebolavirus
Ferrets
Primates
Antibodies
Ebola Hemorrhagic Fever

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge

Woolsey, C., Menicucci, A. R., Cross, R., Luthra, P., Agans, K. N., Borisevich, V., Geisbert, J. B., Mire, C., Fenton, K. A., Jankeel, A., Anand, S., Ebihara, H., Geisbert, T., Messaoudi, I. & Basler, C. F., Sep 17 2019, In : Cell Reports. 28, 12, p. 3032-3046.e6

Research output: Contribution to journalArticle

Open Access
Ebolavirus
Viruses
Virulence
Immunity
Interferon Type I
23 Citations (Scopus)

Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model

Cross, R., Fenton, K. A., Geisbert, J. B., Ebihara, H., Mire, C. & Geisbert, T., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S258-S270

Research output: Contribution to journalArticle

Marburgvirus
Angola
Guinea Pigs
Virus Diseases
Viremia
9 Citations (Scopus)

Current and emerging strategies for the diagnosis, prevention and treatment of Lassa fever

Hartnett, J. N., Boisen, M. L., Oottamasathien, D., Jones, A. B., Millett, M. M., Nelson, D. S., Muncy, I. J., Goba, A., Momoh, M., Fullah, M., Mire, C., Geisbert, J. B., Geisbert, T., Holton, D. L., Rouelle, J. A., Kannadka, C. B., Reyna, A. A., Moses, L. M., Khan, S. H., Gevao, S. M. & 6 others, Grant, D. S., Robinson, J. E., Happi, C., Pitts, K. R., Garry, R. F. & Branco, L. M., May 1 2015, In : Future Virology. 10, 5, p. 559-584 26 p.

Research output: Contribution to journalArticle

Lassa Fever
Lassa virus
Western Africa
Bioterrorism
Virus Diseases
6 Citations (Scopus)

Current Ebola Virus Vaccine Progress

Marzi, A. & Mire, C., Jan 1 2019, (Accepted/In press) In : BioDrugs.

Research output: Contribution to journalArticle

Ebola Vaccines
Vaccines
Immunity
Ebola Hemorrhagic Fever
Ebolavirus

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells

Shabman, R. S., Jabado, O. J., Mire, C. E., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. W. & Basler, C. F., 2014, In : mBio. 5, 6, p. e02011

Research output: Contribution to journalArticle

Marburgvirus
Ebolavirus
High-Throughput Nucleotide Sequencing
RNA
Messenger RNA
40 Citations (Scopus)

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAS in infected cells

Shabman, R. S., Jabado, O. J., Mire, C., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. & Basler, C. F., Sep 25 2014, In : mBio. 5, 6, e02011-14.

Research output: Contribution to journalArticle

Marburgvirus
Ebolavirus
High-Throughput Nucleotide Sequencing
Messenger RNA
Nucleoproteins
33 Citations (Scopus)

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins

Edwards, M. R., Liu, G., Mire, C., Sureshchandra, S., Luthra, P., Yen, B., Shabman, R. S., Leung, D. W., Messaoudi, I., Geisbert, T., Amarasinghe, G. K. & Basler, C. F., Feb 23 2016, In : Cell Reports. 14, 7, p. 1632-1640 9 p.

Research output: Contribution to journalArticle

Marburgvirus
Viruses
Interferons
Ebolavirus
RNA
8 Citations (Scopus)

Disposable cartridge platform for rapid detection of viral hemorrhagic fever viruses

Scherr, S. M., Freedman, D. S., Agans, K. N., Rosca, A., Carter, E., Kuroda, M., Fawcett, H. E., Mire, C., Geisbert, T., Ünlü, M. S. & Connor, J. H., 2017, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 17, 5, p. 917-925 9 p.

Research output: Contribution to journalArticle

Viral Hemorrhagic Fevers
Viruses
Virion
Virus Attachment
Imaging techniques
40 Citations (Scopus)

Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates

Mire, C., Geisbert, J. B., Agans, K. N., Satterfield, B. A., Versteeg, K. M., Fritz, E. A., Feldmann, H., Hensley, L. E. & Geisbert, T., Apr 23 2014, In : PLoS One. 9, 4, e94355.

Research output: Contribution to journalArticle

Marburg virus
Marburgvirus
Vesiculovirus
Vesicular Stomatitis
Filoviridae
1 Citation (Scopus)

Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates

Gilchuk, P., Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Cross, R., Slaughter, J. C., Flyak, A. I., Mani, J., Pauly, M. H., Velasco, J., Whaley, K. J., Zeitlin, L., Geisbert, T. & Crowe, J. E., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S565-S573

Research output: Contribution to journalArticle

Virus Diseases
Primates
Monoclonal Antibodies
Viruses
Macaca mulatta
5 Citations (Scopus)

Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses

Daaboul, G. G., Freedman, D. S., Scherr, S. M., Carter, E., Rosca, A., Bernstein, D., Mire, C., Agans, K. N., Hoenen, T., Geisbert, T., Selim Ünlü, M. & Connor, J. H., Jun 1 2017, In : PLoS One. 12, 6, e0179728.

Research output: Contribution to journalArticle

Zika virus
Ebolavirus
Viruses
virion
Virion
2 Citations (Scopus)

Erratum: Analytical performance characteristics of the cepheid genexpert ebola assay for the detection of ebola virus (PLoS One)

Pinsky, B. A., Sahoo, M. K., Sandlund, J., Kleman, M., Kulkarni, M., Grufman, P., Nygren, M., Kwiatkowski, R., Baron, E. J., Tenover, F., Denison, B., Higuchi, R., Van Atta, R., Beer, N. R., Carrillo, A. C., Naraghi-Arani, P., Mire, C., Ranadheera, C., Grolla, A., Lagerqvist, N. & 1 others, Persing, D. H., Dec 1 2015, In : PLoS One. 10, 12, 0145896.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Glycoprotein-dependent acidification of vesicular stomatitis virus enhances release of matrix protein

Mire, C., Dube, D., Delos, S. E., White, J. M. & Whitt, M. A., Dec 2009, In : Journal of Virology. 83, 23, p. 12139-12150 12 p.

Research output: Contribution to journalArticle

Virus Release
Vesiculovirus
Vesicular Stomatitis
acidification
glycoproteins
26 Citations (Scopus)

Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever

Mire, C., Cross, R., Geisbert, J. B., Borisevich, V., Agans, K. N., Deer, D. J., Heinrich, M. L., Rowland, M. M., Goba, A., Momoh, M., Boisen, M. L., Grant, D. S., Fullah, M., Khan, S. H., Fenton, K. A., Robinson, J. E., Branco, L. M., Garry, R. F. & Geisbert, T., Oct 1 2017, In : Nature Medicine. 23, 10, p. 1146-1149 4 p.

Research output: Contribution to journalArticle

Lassa Fever
Lassa virus
Western Africa
Macaca
Viruses
10 Citations (Scopus)

Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants

Versteeg, K., Menicucci, A. R., Woolsey, C., Mire, C., Geisbert, J. B., Cross, R., Agans, K. N., Jeske, D., Messaoudi, I. & Geisbert, T., Dec 1 2017, In : Scientific Reports. 7, 1, 9730.

Research output: Contribution to journalArticle

Ebolavirus
Democratic Republic of the Congo
Infection
Disease Progression
Genes
2 Citations (Scopus)

Inhibition of the host antiviral response by Nipah virus: Current understanding and future perspectives

Satterfield, B. A., Geisbert, T. & Mire, C., May 1 2016, In : Future Virology. 11, 5, p. 331-344 14 p.

Research output: Contribution to journalArticle

Nipah Virus
Antiviral Agents
Viral Proteins
Acute Disease
Encephalitis
8 Citations (Scopus)

Isolation and characterization of a novel gammaherpesvirus from a microbat cell line

Shabman, R. S., Shrivastava, S., Tsibane, T., Attie, O., Jayaprakash, A., Mire, C., Dilley, K. E., Puri, V., Stockwell, T. B., Geisbert, T., Sachidanandam, R. & Basler, C. F., Jan 1 2016, In : mSphere. 1, 1, e00070-15.

Research output: Contribution to journalArticle

Rhadinovirus
Open Reading Frames
High-Throughput Nucleotide Sequencing
Cell Line
Vero Cells
45 Citations (Scopus)

Lead Precipitation by Vibrio harveyi: Evidence for Novel Quorum-Sensing Interactions

Mire, C., Tourjee, J. A., O'Brien, W. F., Ramanujachary, K. V. & Hecht, G. B., Feb 2004, In : Applied and Environmental Microbiology. 70, 2, p. 855-864 10 p.

Research output: Contribution to journalArticle

Vibrio harveyi
Quorum Sensing
quorum sensing
Vibrio
mutants
135 Citations (Scopus)

Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates

Thi, E. P., Mire, C., Lee, A. C. H., Geisbert, J. B., Zhou, J. Z., Agans, K. N., Snead, N. M., Deer, D. J., Barnard, T. R., Fenton, K. A., Maclachlan, I. & Geisbert, T., May 21 2015, In : Nature. 521, 7552, p. 362-365 4 p.

Research output: Contribution to journalArticle

Ebolavirus
Nanoparticles
Primates
Small Interfering RNA
Disease Outbreaks
5 Citations (Scopus)

Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret (Mustela putorius furo)

Cross, R., Mire, C., Agans, K. N., Borisevich, V., Fenton, K. A. & Geisbert, T., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S448-S452

Research output: Contribution to journalArticle

Marburgvirus
Ferrets
Ebolavirus
Viremia
Immunity
44 Citations (Scopus)

Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA

Thi, E. P., Mire, C., Ursic-Bedoya, R., Geisbert, J. B., Lee, A. C. H., Agans, K. N., Robbins, M., Deer, D. J., Fenton, K. A., MacLachlan, I. & Geisbert, T., Aug 20 2014, In : Science Translational Medicine. 6, 250, 250ra116.

Research output: Contribution to journalArticle

Marburgvirus
Virus Diseases
Angola
Primates
Small Interfering RNA
28 Citations (Scopus)

Modeling the Disease Course of Zaire ebolavirus Infection in the Outbred Guinea Pig

Cross, R., Fenton, K. A., Geisbert, J. B., Mire, C. & Geisbert, T., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S305-S315

Research output: Contribution to journalArticle

Ebolavirus
Democratic Republic of the Congo
Guinea Pigs
Primates
Ebola Hemorrhagic Fever
13 Citations (Scopus)

Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly from Blood

Benzine, J. W., Brown, K. M., Agans, K. N., Godiska, R., Mire, C., Gowda, K., Converse, B., Geisbert, T., Mead, D. A. & Chander, Y., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S234-S242

Research output: Contribution to journalArticle

Point-of-Care Systems
Ebolavirus
Molecular Pathology
Routine Diagnostic Tests
RNA-Directed DNA Polymerase
98 Citations (Scopus)

Mutual antagonism between the ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome

Luthra, P., Ramanan, P., Mire, C., Weisend, C., Tsuda, Y., Yen, B., Liu, G., Leung, D. W., Geisbert, T., Ebihara, H., Amarasinghe, G. K. & Basler, C. F., Jul 17 2013, In : Cell Host and Microbe. 14, 1, p. 74-84 11 p.

Research output: Contribution to journalArticle

Ebolavirus
Viral RNA
Ebola Hemorrhagic Fever
Pattern Recognition Receptors
Virus Replication
11 Citations (Scopus)

Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus

Mire, C., Geisbert, J. B., Agans, K. N., Deer, D. J., Fenton, K. A. & Geisbert, T., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S263-S267

Research output: Contribution to journalArticle

Ebolavirus
Primates
Ebola Hemorrhagic Fever
Aerosols
Infection
17 Citations (Scopus)

Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates

Mire, C., Geisbert, J. B., Agans, K. N., Thi, E. P., Lee, A. C. H., Fenton, K. A. & Geisbert, T., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S367-S374

Research output: Contribution to journalArticle

Ebola Hemorrhagic Fever
Ebolavirus
Passive Immunization
Primates
Democratic Republic of the Congo
24 Citations (Scopus)

Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy

Mire, C., Satterfield, B. A., Geisbert, J. B., Agans, K. N., Borisevich, V., Yan, L., Chan, Y. P., Cross, R., Fenton, K. A., Broder, C. C. & Geisbert, T., Aug 3 2016, In : Scientific Reports. 6, 30916.

Research output: Contribution to journalArticle

Nipah Virus
Bangladesh
Malaysia
Primates
Antibodies
18 Citations (Scopus)

Polyamines and hypusination are required for ebolavirus gene expression and replication

Olsen, M. E., Filone, C. M., Rozelle, D., Mire, C., Agans, K. N., Hensley, L. & Connor, J. H., Jul 1 2016, In : mBio. 7, 4, e00882-16.

Research output: Contribution to journalArticle

Ebolavirus
Polyamines
Eukaryotic Initiation Factors
Gene Expression
Viral Structures
2 Citations (Scopus)

Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates

Woolsey, C., Geisbert, J. B., Matassov, D., Agans, K. N., Borisevich, V., Cross, R., Deer, D. J., Fenton, K. A., Eldridge, J. H., Mire, C. & Geisbert, T., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S582-S587

Research output: Contribution to journalArticle

Marburgvirus
Angola
Vesicular Stomatitis
Primates
Macaca
27 Citations (Scopus)

Protection against lethal marburg virus infection mediated by lipid encapsulated small interfering RNA

Ursic-Bedoya, R., Mire, C., Robbins, M., Geisbert, J. B., Judge, A., MacLachlan, I. & Geisbert, T., Feb 15 2014, In : Journal of Infectious Diseases. 209, 4, p. 562-570 9 p.

Research output: Contribution to journalArticle

Marburgvirus
Virus Diseases
Small Interfering RNA
Lipids
Angola
61 Citations (Scopus)

Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates

Mire, C., Miller, A. D., Carville, A., Westmoreland, S. V., Geisbert, J. B., Mansfield, K. G., Feldmann, H., Hensley, L. E. & Geisbert, T., Mar 2012, In : PLoS Neglected Tropical Diseases. 6, 3, e1567.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Primates
Glycoproteins
Vaccines
Viruses
13 Citations (Scopus)

Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA

Thi, E. P., Lee, A. C. H., Geisbert, J. B., Ursic-Bedoya, R., Agans, K. N., Robbins, M., Deer, D. J., Fenton, K. A., Kondratowicz, A. S., MacLachlan, I., Geisbert, T. & Mire, C., Aug 22 2016, In : Nature Microbiology. 1, 16142.

Research output: Contribution to journalArticle

Ebolavirus
Sudan
Primates
Small Interfering RNA
Nanoparticles
64 Citations (Scopus)

Single-dose attenuated Vesiculovax vaccines protect primates against Ebola Makona virus

Mire, C., Matassov, D., Geisbert, J. B., Latham, T. E., Agans, K. N., Xu, R., Ota-Setlik, A., Egan, M. A., Fenton, K. A., Clarke, D. K., Eldridge, J. H. & Geisbert, T., Apr 30 2015, In : Nature. 520, 7549, p. 688-691 4 p.

Research output: Contribution to journalArticle

Ebolavirus
Attenuated Vaccines
Democratic Republic of the Congo
Primates
Vaccines
8 Citations (Scopus)

Single-dose trivalent VesiculoVax vaccine protects macaques from lethal Ebolavirus and Marburgvirus challenge

Matassov, D., Mire, C., Latham, T., Geisbert, J. B., Xu, R., Ota-Setlik, A., Agans, K. N., Kobs, D. J., Wendling, M. Q. S., Burnaugh, A., Rudge, T. L., Sabourin, C. L., Egan, M. A., Clarke, D. K., Geisbert, T. & Eldridge, J. H., Feb 1 2018, In : Journal of Virology. 92, 3, e01190-17.

Research output: Contribution to journalArticle

Marburgvirus
Ebolavirus
Filoviridae
Vesiculovirus
Vesicular Stomatitis
31 Citations (Scopus)

Single injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease

Mire, C., Versteeg, K. M., Cross, R., Agans, K. N., Fenton, K. A., Whitt, M. A. & Geisbert, T., Dec 13 2013, In : Virology Journal. 10, 353.

Research output: Contribution to journalArticle

Nipah Virus
Ferrets
Vesicular Stomatitis
Virus Diseases
Vaccines
5 Citations (Scopus)

siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease

Thi, E. P., Mire, C., Lee, A. C. H., Geisbert, J. B., Ursic-Bedoya, R., Agans, K. N., Robbins, M., Deer, D. J., Cross, R., Kondratowicz, A. S., Fenton, K. A., MacLachlan, I. & Geisbert, T., Dec 1 2017, In : Journal of Clinical Investigation. 127, 12, p. 4437-4448 12 p.

Research output: Contribution to journalArticle

Marburg Virus Disease
Marburgvirus
Primates
Small Interfering RNA
Viruses
20 Citations (Scopus)

Targeting innate immunity for antiviral therapy through small molecule agonists of the RLR pathway

Pattabhi, S., Wilkins, C. R., Dong, R., Knoll, M. L., Posakony, J., Kaiser, S., Mire, C., Wang, M. L., Ireton, R. C., Geisbert, T., Bedard, K. M., Iadonato, S. P., Loo, Y. M. & Gale, M., 2016, In : Journal of Virology. 90, 5, p. 2372-2387 16 p.

Research output: Contribution to journalArticle

Interferon Regulatory Factor-3
Innate Immunity
agonists
Antiviral Agents
viruses
37 Citations (Scopus)

The domestic ferret (mustela putorius furo) as a lethal infection model for 3 species of ebolavirus

Cross, R., Mire, C., Borisevich, V., Geisbert, J. B., Fenton, K. A. & Geisbert, T., Aug 15 2016, In : Journal of Infectious Diseases. 214, 4, p. 565-569 5 p.

Research output: Contribution to journalArticle

Ebolavirus
Ferrets
Animal Models
Primate Diseases
Filoviridae