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20152024

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  • Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference

    Kloske, C. M., Belloy, M. E., Blue, E. E., Bowman, G. R., Carrillo, M. C., Chen, X., Chiba-Falek, O., Davis, A. A., Paolo, G. D., Garretti, F., Gate, D., Golden, L. R., Heinecke, J. W., Herz, J., Huang, Y., Iadecola, C., Johnson, L. A., Kanekiyo, T., Karch, C. M. & Khvorova, A. & 40 others, Koppes-den Hertog, S. J., Lamb, B. T., Lawler, P. E., Guen, Y. L., Litvinchuk, A., Liu, C. C., Mahinrad, S., Marcora, E., Marino, C., Michaelson, D. M., Miller, J. J., Morganti, J. M., Narayan, P. S., Naslavsky, M. S., Oosthoek, M., Ramachandran, K. V., Ramakrishnan, A., Raulin, A. C., Robert, A., Saleh, R. N. M., Sexton, C., Shah, N., Shue, F., Sible, I. J., Soranno, A., Strickland, M. R., Tcw, J., Thierry, M., Tsai, L. H., Tuckey, R. A., Ulrich, J. D., van der Kant, R., Wang, N., Wellington, C. L., Weninger, S. C., Yassine, H. N., Zhao, N., Bu, G., Goate, A. M. & Holtzman, D. M., Sep 2024, In: Alzheimer's and Dementia. 20, 9, p. 6590-6605 16 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    3 Scopus citations
  • An mRNA-encoded dominant-negative inhibitor of transcription factor RUNX1 suppresses vitreoretinal disease in experimental models

    O Hare, M., Miller, W. P., Arevalo-Alquichire, S., Amarnani, D., Apryani, E., Perez-Corredor, P., Marino, C., Shu, D. Y., Vanderleest, T. E., Muriel-Torres, A., Gordon, H. B., Gunawan, A. L., Kaplan, B. A., Barake, K. W., Bejjani, R. P., Doan, T. H., Lin, R., Delgado-Tirado, S., Gonzalez-Buendia, L. & Rossin, E. J. & 8 others, Zhao, G., Eliott, D., Weinl-Tenbruck, C., Chevessier-Tönnesen, F., Rejman, J., Montrasio, F., Kim, L. A. & Arboleda-Velasquez, J. F., Nov 27 2024, In: Science Translational Medicine. 16, 775, eadh0994.

    Research output: Contribution to journalArticlepeer-review

  • APOE3 Christchurch modulates β-catenin/Wnt signaling in iPS cell-derived cerebral organoids from Alzheimer’s cases

    Perez-Corredor, P., Vanderleest, T. E., Vacano, G. N., Sanchez, J. S., Villalba-Moreno, N. D., Marino, C., Krasemann, S., Mendivil-Perez, M. A., Aguillón, D., Jiménez-Del-Río, M., Baena, A., Sepulveda-Falla, D., Lopera, F., Quiroz, Y. T., Arboleda-Velasquez, J. F. & Mazzarino, R. C., 2024, In: Frontiers in Molecular Neuroscience. 17, 1373568.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation

    Marino, C., Perez-Corredor, P., O'Hare, M., Heuer, A., Chmielewska, N., Gordon, H., Chandrahas, A. S., Gonzalez-Buendia, L., Delgado-Tirado, S., Doan, T. H., Vanderleest, T. E., Arevalo-Alquichire, S., Obar, R. A., Ortiz-Cordero, C., Villegas, A., Sepulveda-Falla, D., Kim, L. A., Lopera, F., Mahley, R. & Huang, Y. & 2 others, Quiroz, Y. T. & Arboleda-Velasquez, J. F., Feb 2024, In: Alzheimer's and Dementia. 20, 2, p. 819-836 18 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man

    Lopera, F., Marino, C., Chandrahas, A. S., O’Hare, M., Villalba-Moreno, N. D., Aguillon, D., Baena, A., Sanchez, J. S., Vila-Castelar, C., Ramirez Gomez, L., Chmielewska, N., Oliveira, G. M., Littau, J. L., Hartmann, K., Park, K., Krasemann, S., Glatzel, M., Schoemaker, D., Gonzalez-Buendia, L. & Delgado-Tirado, S. & 22 others, Arevalo-Alquichire, S., Saez-Torres, K. L., Amarnani, D., Kim, L. A., Mazzarino, R. C., Gordon, H., Bocanegra, Y., Villegas, A., Gai, X., Bootwalla, M., Ji, J., Shen, L., Kosik, K. S., Su, Y., Chen, Y., Schultz, A., Sperling, R. A., Johnson, K., Reiman, E. M., Sepulveda-Falla, D., Arboleda-Velasquez, J. F. & Quiroz, Y. T., May 2023, In: Nature Medicine. 29, 5, p. 1243-1252 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    62 Scopus citations