Courtney Townsend, MD

  • 12061 Citations
  • 57 h-Index
1961 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
1998

Novel expression and regulation of gastrin gene in human ovarian cancer cell line, SW626

Kim, H. J., Evers, B. M., Banker, N. A., Greeley, G. H., Hellmich, M. R., Thompson, J. C. & Townsend, C. M., Aug 13 1998, In : Digestive Diseases and Sciences. 43, 7, p. 1465-1473 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Stimulation of prohormone convertase-1 mRNA expression by second messenger signaling systems

Udupi, V., Townsend, C. M. & Greeley, G. H., May 19 1998, In : Biochemical and Biophysical Research Communications. 246, 2, p. 463-465 3 p.

Research output: Contribution to journalArticle

17 Scopus citations
1997

A Functional in Vitro Model to Examine Signaling Mechanisms in Gastrin-Mediated Human Cell Growth

Kim, H. J., Evers, B. M., Banker, N. A., Hellmich, M. R. & Towsend, C. M., Jan 1 1997, In : Journal of Gastrointestinal Surgery. 1, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Antitumor effect of positively charged resin in the hamster cheek pouch model

Simmons, D. J., Seitz, P. K., Cooper, C. W., Krukowski, M. & Townsend, C. M., Mar 5 1997, In : Journal of Biomedical Materials Research. 34, 3, p. 393-400 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Caloric restriction causes secretagogue specific changes of gastric acid secretion in rats

Higashide, S., Chu, K. U., Gomez, G., Greeley, G. H., Thompson, J. C. & Townsend, C. M., Feb 26 1997, In : Regulatory Peptides. 68, 3, p. 205-210 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cyclin-dependent kinase inhibitors block proliferation of human gastric cancer cells

Iseki, H., Ko, T. C., Xue, X. Y., Seapan, A., Hellmich, M. R. & Townsend, C. M., Aug 1997, In : Surgery. 122, 2, p. 187-195 9 p.

Research output: Contribution to journalArticle

42 Scopus citations

Inhibition of neurotensin-induced pancreatic carcinoma growth by a nonpeptide neurotensin receptor antagonist, SR48692

Iwase, K., Evers, B. M., Hellmich, M. R., Kim, H. J., Higashide, S., Gully, D., Thompson, J. C. & Townsend, C. M., May 1 1997, In : Cancer. 79, 9, p. 1787-1793 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Regulation of growth of human gastric cancer by gastrin and glycine- extended progastrin

Iwase, K., Evers, B. M., Hellmich, M. R., Guo, Y. S., Higashide, S., Hong Jin Kim, J. K. & Townsend, J., Jan 1 1997, In : Gastroenterology. 113, 3, p. 782-790 9 p.

Research output: Contribution to journalArticle

87 Scopus citations

Src-mediated activation of the human neurotensin/neuromedin N promoter

Banker, N. A., Hellmich, M. R., Kim, H. J., Townsend, C. M. & Evers, B. M., Aug 1997, In : Surgery. 122, 2, p. 180-186 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
1996

All-trans-Retmoic Acid Inhibits Growth of Human Pancreatic Cancer Cell Lines

Bold, R. J., Ishizuka, J., Townsend, C. M. & Thompson, J. C., Jan 1 1996, In : Pancreas. 12, 2, p. 189-195 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Bombesin-mediated AP-1 activation in a human gastric cancer (SIIA)

Kim, H. J., Evers, B. M., Guo, Y., Banker, N. A., Hellmich, M. R. & Townsend, J., Jan 1 1996, In : Surgery. 120, 2, p. 130-137 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Caloric restriction increases the expression of heat shock protein in the gut

Ehrenfried, J. A., Evers, B. M., Chu, K. U., Townsend, C. M. & Thompson, J. C., May 21 1996, In : Annals of surgery. 223, 5, p. 592-599 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Fetal and neoplastic expression of the neurotensin gene in the human colon

Evers, B. M., Zhou, Z., Dohlen, V., Rajaraman, S., Thompson, J. C. & Townsend, C. M., May 21 1996, In : Annals of surgery. 223, 5, p. 464-471 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Glycine-extended gastrin potentiates gastrin-stimulated gastric acid secretion in rats

Higashide, S., Gomez, G., Greeley, G. H., Townsend, C. M. & Thompson, J. C., Feb 26 1996, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 270, 1 33-1, p. G220-G224

Research output: Contribution to journalArticle

34 Scopus citations

Human monoclonal antibody against colon cancer

Yao, C. Z., Ishizuka, J., Bold, R. J., Sperling, H. E., Townsend, C. M. & Thompson, J. C., Jan 1 1996, In : Cancer Investigation. 14, 3, p. 211-217 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Hyperphosphorylation of retinoblastoma protein and stimulation of growth by okadaic acid in human pancreatic cancer

Hirai, A., Bold, R. J., Ishizuka, J., Hirai, M., Townsend, C. M. & Thompson, J. C., Nov 13 1996, In : Digestive Diseases and Sciences. 41, 10, p. 1975-1980 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Indirect inhibitory effect of a neurotensin receptor antagonist on human colon cancer (LoVo) growth

Iwase, K., Evers, B. M., Hellmich, M. R., Kim, H. J., Higashide, S., Gully, D. & Townsend, C. M., Jan 1 1996, In : Surgical oncology. 5, 5-6, p. 245-251 7 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mechanisms of bombesin on growth of gastrinoma (PT) in vivo

Chu, K. U., Ishizuka, J., Battey, J. F., Uchida, T., Beauchamp, R. D., Townsend, C. M. & Thompson, J. C., Jan 1 1996, In : Digestive Diseases and Sciences. 41, 11, p. 2180-2186 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Pancreatic growth after distal small bowel resection is altered with aging

Yoshinaga, K., Ishizuka, J., Townsend, C. M. & Thompson, J. C., Jan 1 1996, In : AGE. 19, 1, p. 7-12 6 p.

Research output: Contribution to journalArticle

Pancreatic growth after distal small bowel resection is altered with aging

Yoshinaga, K., Ishizuka, J., Townsend, C. & Thompson, J. C., Jan 1 1996, In : Journal of the American Aging Association. 19, 1, p. 7-12 6 p.

Research output: Contribution to journalArticle

Progress Toward Hormonal Therapy of Gastrointestinal Cancer

Bold, R. J., Ishizuka, J. & Townsend, C. M., Jan 1 1996, In : Annals of surgery. 223, 1, p. 4-11 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Regulation of peptide YY homeostasis by gastric acid and gastrin

Gomez, G., Padilla, L., Udupi, V., Tarasova, N., Sundler, F., Townsend, C. M., Thompson, J. C. & Greeley, G. H., Jan 1 1996, In : Endocrinology. 137, 4, p. 1365-1369 5 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Short-term caloric restriction augments age-related decreases in gastrin content and release

Chu, K. U., Evers, B. M., Ishizuka, J., Beauchamp, R. D., Greeley, G. H., Townsend, C. M. & Thompson, J. C., May 24 1996, In : Mechanisms of Ageing and Development. 87, 1, p. 25-33 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Stimulation of pancreatic growth: Distal small bowel resection mediated by increased levels of cholecystokinin

Yoshinaga, K., Ishizuka, J., Gomez, G., Izukura, M., Townsend, C. M., Mishima, Y. & Thompson, J. C., Aug 27 1996, In : Annals of surgery. 224, 2, p. 139-144 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
1995

Bombesin stimulates mucosal growth in jejunal and ileal Thiry-Vella fistulas

Chu, K. U., Higashide, S. I., Evers, B. M., Ishizuka, J., Townsend, C. M. & Thompson, J. C., May 1995, In : Annals of surgery. 221, 5, p. 602-611 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Characterization of promoter elements required for cell-specific expression of the neurotensin/neuromedin N gene in a human endocrine cell line

Evers, B. M., Wang, X., Zhou, Z., Townsend, C. M., Mcneil, G. P. & Dobner, P. R., Jul 1995, In : Molecular and Cellular Biology. 15, 7, p. 3870-3881 12 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations

Differential regulation by TGF-β1 and insulin of insulin-like growth factor binding protein-2 in IEC-6 cells

Guo, Y. S., Townsend, C. M., Jin, G. F., Beauchamp, R. D. & Thompson, J. C., Jan 1 1995, In : American Journal of Physiology - Endocrinology and Metabolism. 268, 6 31-6, p. E1199-E1204

Research output: Contribution to journalArticle

15 Scopus citations

Downregulation of prohormone convertase-1 by a phorbol ester

Udupi, V., Townsend, C. M., Gomez, G., Zhang, T. & Greeley, G. H., Dec 14 1995, In : Biochemical and Biophysical Research Communications. 217, 2, p. 495-500 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Effect of ileo-jejunal transposition on the growth of the GI tract and pancreas in young and aged rats

Tsuchiya, T., Ishizuka, J., Sato, K., Shimoda, I., Rajaraman, S., Uchida, T., Townsend, C. M. & Thompson, J. C., Jan 1 1995, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 50, 3, p. M155-M161

Research output: Contribution to journalArticle

6 Scopus citations

Growth of mouse hepatocytes is stimulated by gastrin

Yao, C. Z., Bold, R. J., Ishizuka, J., Townsend, C. M. & Thompson, J. C., Jun 1995, In : Journal of Cellular Physiology. 163, 3, p. 532-537 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Heat shock proteins are differentially expressed in human gastrointestinal cancers

Ehrenfried, J. A., Herron, B. E., Townsend, C. M. & Evers, B. M., Jan 1 1995, In : Surgical oncology. 4, 4, p. 197-203 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Increases in nup475 and c-jun are early molecular events that precede the adaptive hyperplastic response after small bowel resection

Ehrenfried, J. A., Townsend, C. M., Thompson, J. C. & Evers, B. M., Jul 1995, In : Annals of surgery. 222, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Insulin-like growth factor-II expression in carcinoma in colon cell lines: Implications for autocrine actions

Guo, Y. S., Jin, G. F., Townsend, C. M., Zhang, T., Sheng, H. M., Beauchamp, R. D. & Thompson, J. C., Jan 1 1995, In : Journal of the American College of Surgeons. 181, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Intestinal peptide YY: Ontogeny of gene expression in rat bowel and trophic actions on rat and mouse bowel

Gomez, G., Zhang, T., Rajaraman, S., Thakore, K. N., Yanaihara, N., Townsend, C. M., Thompson, J. C. & Greeley, G. H., Jan 1 1995, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 268, 1 31-1, p. G71-G81

Research output: Contribution to journalArticle

60 Scopus citations

Nerve Growth Factor as a Mitogen for a Pancreatic Carcinoid Cell Line

Bold, R. J., Ishizuka, J., Rajaraman, S., Perez‐Polo, J. R., Townsend, C. M. & Thompson, J. C., Jun 1995, In : Journal of neurochemistry. 64, 6, p. 2622-2628 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Pancreatic growth after distal small bowel resection is altered with aging

Yoshinaga, K., Ishizuka, J., Townsend, C. M. & Thompson, J. C., Apr 1 1995, In : AGE. 18, 2, p. 63-68 6 p.

Research output: Contribution to journalArticle

Peptide YY

Gomez, G., Zhang, T., Lluis, F., Townsend, C. M., Thompson, J. C. & Greeley, G. H., Jan 1 1995, In : Biomedical Research. 16, SUPPL. 2, p. 147-150 4 p.

Research output: Contribution to journalArticle

Phorbol ester-induced alteration in the pattern of secretion and storage of chromogranin A and neurotensin in a human pancreatic carcinoid cell line

Zhang, T., Townsend, C. M., Udupi, V., Yanaihara, N., Rajaraman, S., Beauchamp, R. D., Ishizuka, J., Evers, B. M., Gomez, G., Thompson, J. C. & Greeley, G. H., May 1995, In : Endocrinology. 136, 5, p. 2252-2261 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Role of bombesin on gut mucosal growth

Chu, K. U., Evers, B. M., Ishizuka, J., Townsend, C. M. & Thompson, J. C., Jul 1995, In : Annals of surgery. 222, 1, p. 94-100 7 p.

Research output: Contribution to journalArticle

49 Scopus citations

Role of calcium in the regulation of ornithine decarboxylase enzyme activity in mouse colon cancer cells

Ishizuka, J., Bold, R. J., Townsend, C. M. & Thompson, J. C., Jan 1 1995, In : Cancer Investigation. 13, 2, p. 181-187 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Secretin potentiates cholecystokinin‐stimulated amylase release by AR4‐2J cells via a stimulation of phospholipase C

Bold, R. J., Ishizuka, J., Townsend, C. M. & Thompson, J. C., Oct 1995, In : Journal of Cellular Physiology. 165, 1, p. 172-176 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Trophic response of gut and pancreas after ileojejunal transposition

Chu, K. U., Tsuchiya, T., Ishizuka, J., Uchida, T., Townsend, C. M. & Thompson, J. C., Mar 1995, In : Annals of surgery. 221, 3, p. 249-256 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
1994

Activation of hepatic proliferation-associated transcription factors by lipopolysaccharide

Beauchamp, R. D., Papaconstantinou, J., Henderson, A. M., Sheng, H. M., Townsend, C. M., Thompson, J. C., Christou, N. V., Barke, R. A., Billiar, T., Forse, R. A. & Baker, C. C., Jan 1 1994, In : Surgery. 116, 2, p. 367-377 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Age-dependent increase of neurotensin expression in the ileum

Shimoda, I., Evers, B. M., Sato, K., Ishizuka, J., Rajaraman, S., Chung, D. H., Uchida, T., Tsuchiya, T., Greeley, G. H., Townsend, C. M. & Thompson, J. C., Jan 1 1994, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 266, 4 29-4, p. G706-G712

Research output: Contribution to journalArticle

4 Scopus citations

Analysis of multiple molecular changes in human endocrine tumours

Arany, I., Rady, P., Evers, B. M., Tyring, S. K. & Townsend, C. M., Jun 1994, In : Surgical oncology. 3, 3, p. 153-159 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Bombesin improves survival from methotrexate-induced enterocolitis

Chu, K. U., Higashide, S. I., Evers, B. M., Rajaraman, S., Ishizuka, J., Townsend, C. M. & Thompson, J. C., Oct 1994, In : Annals of surgery. 220, 4, p. 570-577 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Bombesin inhibits growth of pancreatic ductal adenocarcinoma (H2T) in nude mice

Farre, A., Ishizuka, J., Gomez, G., Mark Evers, B., Saydjari, R., Koo, J. Y., Townsend, C. M. & Thompson, J. C., Sep 1994, In : Pancreas. 9, 5, p. 652-656 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Bombesin stimulates the in vitro growth of a human gastric cancer cell line

Bold, R. J., Lowry, P. S., Ishizuka, J., Battey, J. F., Townsend, C. M. & Thompson, J. C., Dec 1994, In : Journal of Cellular Physiology. 161, 3, p. 519-525 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

BON cells display the intestinal pattern of neurotensin/neuromedin N precursor processing

Carraway, R. E., Mitra, S. P., Evers, B. M. & Townsend, C. M., Aug 31 1994, In : Regulatory Peptides. 53, 1, p. 17-29 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Characterization of a human pancreatic carcinoid in vitro: Morphology, amine and peptide storage, and secretion

Parekh, D., Ishizuka, J., Townsend, C. M., Haber, B., Daniel Beauchamp, R., Karp, G., Whe Kim, S., Rajaraman, S., Greeley, G. & Thompson, J. C., Jan 1994, In : Pancreas. 9, 1, p. 83-90 8 p.

Research output: Contribution to journalArticle

98 Scopus citations