Photo of Daniel Felsing

Daniel Felsing

  • 44 Citations
  • 3 h-Index
20142021
If you made any changes in Pure, your changes will be visible here soon.

Research Output 2014 2019

  • 44 Citations
  • 3 h-Index
  • 8 Article
  • 2 Comment/debate
  • 1 Letter
2019
1 Citation (Scopus)

Advances in Dopamine D1 Receptor Ligands for Neurotherapeutics

Felsing, D., Jain, M. & Allen, J., Jul 12 2019, In : Current Topics in Medicinal Chemistry. 19, 16, p. 1365 - 1380 15 p.

Research output: Contribution to journalArticle

Dopamine D1 Receptors
Ligands
Pharmaceutical Chemistry
Structure-Activity Relationship
Reward
2 Citations (Scopus)

Ligand-directed serotonin 5-HT 2C receptor desensitization and sensitization

Felsing, D., Canal, C. E. & Booth, R. G., Apr 5 2019, In : European Journal of Pharmacology. p. 131-139 9 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2C
Serotonin
Ligands
Type C Phospholipases
Serotonin Receptor Agonists
1 Citation (Scopus)

Serotonin 5-HT2C Receptor Cys23Ser Single Nucleotide Polymorphism Associates with Receptor Function and Localization In Vitro

Land, M. A., Chapman, H. L., Davis-Reyes, B. D., Felsing, D. E., Allen, J. A., Moeller, F. G., Elferink, L. A., Cunningham, K. A. & Anastasio, N. C., Dec 1 2019, In : Scientific reports. 9, 1, 16737.

Research output: Contribution to journalArticle

Open Access
Receptor, Serotonin, 5-HT2C
Single Nucleotide Polymorphism
Alleles
Pharmacology
Cell Line
2 Citations (Scopus)

Synthesis and pharmacological evaluation of non-catechol G protein biased and unbiased dopamine D1 receptor agonists

Wang, P., Felsing, D., Chen, H., Raval, S., Allen, J. & Zhou, J., May 9 2019, In : ACS Medicinal Chemistry Letters. 10.1021/acsmedchemlett.9b00050, p. 792-799 8 p., 10.1021/acsmedchemlett.9b00050.

Research output: Contribution to journalArticle

Open Access
Dopamine D1 Receptors
Dopamine Agonists
GTP-Binding Proteins
Arrestin
Dopamine
2018
9 Citations (Scopus)

Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction

Felsing, D., Anastasio, N., Miszkiel, J. M., Gilbertson, S. R., Allen, J. & Cunningham, K., Aug 1 2018, In : PLoS One. 13, 8, e0203137.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT2C
Receptor, Serotonin, 5-HT2A
serotonin
Serotonin
receptors
2 Citations (Scopus)

Small Molecule Neuromedin U Receptor 2 Agonists Suppress Food Intake and Decrease Visceral Fat in Animal Models.

Sampson, C. M., Kasper, J., Felsing, D., Raval, S., Ye, N., P, W., Rytting, E., Zhou, J., Allen, J. & Hommel, J., Aug 23 2018, In : Pharmacology Research and Perspectives. 6, (5):e00425. , doi: 10.1002/prp2.425.

Research output: Contribution to journalArticle

Open Access
Intra-Abdominal Fat
Animal Models
Eating
Body Weight
neuromedin U receptor
2017

Homology modeling inspired synthesis of 5-HT2A receptor inhibitors: A diazepine analogue of the atypical antipsychotic JL13

Mongeau, E., Yuan, G., Minden, Z., Waldron, S., Booth, R., Felsing, D., Ondrechen, M. J. & Jones, G. B., Jan 1 2017, In : Central Nervous System Agents in Medicinal Chemistry. 17, 3, p. 239-244 6 p.

Research output: Contribution to journalLetter

Receptor, Serotonin, 5-HT2A
Antipsychotic Agents
Clozapine
Libraries
5-(4-methylpiperazin-1-yl)-8-chloropyrido(2,3-b)(1,5)benzoxazepine fumarate
2015
9 Citations (Scopus)

An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist That Corrects Motor Stereotypy in Mouse Models

Canal, C. E., Felsing, D., Liu, Y., Zhu, W., Wood, J. T., Perry, C. K., Vemula, R. & Booth, R. G., Jul 15 2015, In : ACS Chemical Neuroscience. 6, 7, p. 1259-1270 12 p.

Research output: Contribution to journalArticle

Receptor, Serotonin, 5-HT1A
Serotonin
Rett Syndrome
Fragile X Syndrome
Serotonin 5-HT2 Receptor Agonists
Chemical Models
Receptor, Serotonin, 5-HT1A
Neurosciences
Serotonin
2014
18 Citations (Scopus)

A novel Aminotetralin-Type Serotonin (5-HT)2C receptor-specific Agonist and 5-HT2A competitive Antagonist/5-HT2B inverse agonist with preclinical efficacy for Psychoses

Canal, C. E., Morgan, D., Felsing, D., Kondabolu, K., Rowland, N. E., Robertson, K. L., Sakhuja, R. & Booth, R. G., Jan 1 2014, In : Journal of Pharmacology and Experimental Therapeutics. 349, 2, p. 310-318 9 p.

Research output: Contribution to journalArticle

Serotonin 5-HT2 Receptor Agonists
Receptor, Serotonin, 5-HT2C
Serotonin 5-HT2 Receptor Antagonists
Receptor, Serotonin, 5-HT2B
Psychotic Disorders
Serotonin 5-HT2 Receptor Agonists
Receptor, Serotonin, 5-HT2C
Serotonin 5-HT2 Receptor Antagonists
Psychotic Disorders
Serotonin