Personal profile
Research Strategic Pillar
The Chief Research Officer, has determined that UTMB research should be prioritized into six health communities. This researcher has received the following badge(s):
Research Strategic Pillar Keywords
- Specialized Health
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Dive into the research topics where Daniel O'Reilly is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Conjugated Antisense Oligonucleotides for Skipping of Duchenne Muscular Dystrophy Exon 53: A Cautionary Study
Groenwold, E. T., Montulet, A., Stan, T., van de Vijver, D., McCorquodale, D., McHugh, N., Echeverria, D., Winter, C. T. D., van de Wal, M., O'Reilly, D., Khvorova, A., Aartsma-Rus, A. & Damha, M. J., Apr 1 2026, In: Nucleic Acid Therapeutics. 36, 2, p. 100-108 9 p.Research output: Contribution to journal › Article › peer-review
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Lowering the HTT1a transcript as an effective therapy for Huntington's disease in a knockin mouse model
Papadopoulou, A. S., Alterman, J., Landles, C., Smith, E. J., Conroy, F., Phillips, J., Canibano-Pico, M., Nita, I. M., Osborne, G. F., Iqbal, A., Aldous, S. G., Bondulich, M. K., Gomez-Paredes, C., Sathasivam, K., O'Reilly, D., Echeverria, D., Bobkov, K., Greene, J. R., Aronin, N. & Khvorova, A. & 1 others, , Mar 18 2026, In: Science Translational Medicine. 18, 841, p. eadw2495Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Scopus citations -
Presence of phosphodiester backbone, but not nucleobases, in the guide's 3′ terminal region is necessary for RISC loading and target cleavage in vitro and in vivo
O'Reilly, D., Furgal, R. C., Ross, V. M., Luu, E., Gross, K. Y., Hariharan, V., Summers, A., Cooper, D., Allen, S., Dahlke, C., Rachid, M. O., Chan, I. L., Fakih, H. H., Alterman, J. F., Echeverria, D., Watts, J. K. & Khvorova, A., Jan 13 2026, In: Nucleic acids research. 54, 1, gkaf1438.Research output: Contribution to journal › Article › peer-review
Open Access -
RNAi-mediated p38δ silencing mitigates anthracycline cardiotoxicity in female mice
Trampel, K. A., Gross, K. Y., O'reilly, D., Melisova, A., Salman, B., Green, S., George, S. A., Khvorova, A., Efimov, I. R. & Efimova, T., May 2026, In: American Journal of Physiology - Heart and Circulatory Physiology. 330, 5, p. H1522-H1539Research output: Contribution to journal › Article › peer-review
Open Access -
Chemical engineering of CRISPR–Cas systems for therapeutic application
Barber, H. M., Pater, A. A., Gagnon, K. T., Damha, M. J. & O’Reilly, D., Mar 2025, In: Nature Reviews Drug Discovery. 24, 3, p. 209-230 22 p.Research output: Contribution to journal › Review article › peer-review
33 Link opens in a new tab Scopus citations