David Good, PhD

  • 3121 Citations
  • 36 h-Index
1977 …2020

Research output per year

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Research Output

  • 3121 Citations
  • 36 h-Index
  • 78 Article
  • 8 Review article
  • 1 Chapter
2020
2019
2018
1 Scopus citations
2017

Monophosphoryl lipid a induces protection against lps in medullary thick ascending limb through a tlr4-trif-pi3k signaling pathway

Watts, B., George, T., Sherwood, E. R. & Good, D., Jul 7 2017, In : American Journal of Physiology - Renal Physiology. 313, 1, p. F103-F115

Research output: Contribution to journalArticle

7 Scopus citations
2016
2 Scopus citations
2015
2 Scopus citations
2013

A two-hit mechanism for sepsis-induced impairment of renal tubule function

Watts, B. A., George, T., Sherwood, E. R. & Good, D. W., 2013, In : American Journal of Physiology - Renal Physiology. 304, 7, p. F863-F874

Research output: Contribution to journalArticle

17 Scopus citations
19 Scopus citations
2012

Toll-like receptor 2 is required for LPS-induced toll-like receptor 4 signaling and inhibition of ion transport in renal thick ascending limb

Good, D. W., George, T. & Watts, B. A., Jun 8 2012, In : Journal of Biological Chemistry. 287, 24, p. 20208-20220 13 p.

Research output: Contribution to journalArticle

41 Scopus citations
2011

Basolateral LPS inhibits NHE3 and HCO 3 - absorption through TLR4/MyD88- dependent ERK activation in medullary thick ascending limb

Watts, B. A., George, T., Sherwood, E. R. & Good, D. W., Dec 1 2011, In : American Journal of Physiology - Cell Physiology. 301, 6, p. C1296-C1306

Research output: Contribution to journalArticle

25 Scopus citations
7 Scopus citations
2010
23 Scopus citations
2009
44 Scopus citations
2008
24 Scopus citations
2007

Nongenomic actions of aldosterone on the renal tubule

Good, D. W., Apr 1 2007, In : Hypertension. 49, 4, p. 728-739 12 p.

Research output: Contribution to journalReview article

35 Scopus citations
2006
41 Scopus citations

Nongenomic regulation by aldosterone of the epithelial NHE3 Na +/H+ exchanger

Good, D. W., George, T. & Watts, B. A., Mar 1 2006, In : American Journal of Physiology - Cell Physiology. 290, 3, p. C757-C763

Research output: Contribution to journalArticle

31 Scopus citations
2005

The basolateral NHE1 Na+/H+ exchanger regulates transepithelial HCO3- absorption through actin cytoskeleton remodeling in renal thick ascending limb

Watts, B. A., George, T. & Good, D. W., Mar 25 2005, In : Journal of Biological Chemistry. 280, 12, p. 11439-11447 9 p.

Research output: Contribution to journalArticle

40 Scopus citations
2004
11 Scopus citations

Transepithelial HCO3- absorption is defective in renal thick ascending limbs from Na+/H+ exchanger NHE1 null mutant mice

Good, D. W., Watts, B. A., George, T., Meyer, J. W. & Shull, G. E., Dec 1 2004, In : American Journal of Physiology - Renal Physiology. 287, 6 56-6, p. F1244-F1249

Research output: Contribution to journalArticle

38 Scopus citations
2003

Aldosterone potentiates 1,25-dihydroxyvitamin D3 action in renal thick ascending limb via a nongenomic, ERK-dependent pathway

Good, D. W., George, T. & Watts, B. A., Nov 2003, In : American Journal of Physiology - Cell Physiology. 285, 5 54-5, p. C1122-C1130

Research output: Contribution to journalArticle

17 Scopus citations
2002

Aldosterone inhibits HCO3- absorption via a nongenomic pathway in medullary thick ascending limb

Good, D. W., George, T. & Watts, B. A., Oct 2002, In : American Journal of Physiology - Renal Physiology. 283, 4 52-4, p. F699-F706

Research output: Contribution to journalArticle

38 Scopus citations

ERK mediates inhibition of Na+/H+ exchange and HCO3- absorption by nerve growth factor in MTAL

Watts, B. A. & Good, D. W., 2002, In : American Journal of Physiology - Renal Physiology. 282, 6 51-6, p. F1056-F1063

Research output: Contribution to journalArticle

31 Scopus citations
2001

Neurotrophin-3 inhibits HCO3- absorption via a cAMP-dependent pathway in renal thick ascending limb

Good, D. W. & George, T., Dec 1 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1804-C1811

Research output: Contribution to journalArticle

6 Scopus citations
2000

Hyposmolality stimulates Na+/H+ exchange and HCO3/- absorption in thick ascending limb via PI 3-kinase

Good, D. W., Di Mari, J. F. & Watts, B. A., Dec 7 2000, In : American Journal of Physiology - Cell Physiology. 279, 5 48-5, p. C1443-C1454

Research output: Contribution to journalArticle

47 Scopus citations
1999

Angiotensin II inhibits HCO3/- absorption via a cytochrome P-450- dependent pathway in MTAL

Good, D. W., George, T. & Wang, D. H., May 1999, In : American Journal of Physiology - Renal Physiology. 276, 5 45-5, p. F726-F736

Research output: Contribution to journalArticle

68 Scopus citations

Hyposmolality stimulates apical membrane Na+/H+ exchange and HCO3- absorption in renal thick ascending limb

Watts, B. A. & Good, D. W., Dec 1999, In : Journal of Clinical Investigation. 104, 11, p. 1593-1602 10 p.

Research output: Contribution to journalArticle

Open Access
46 Scopus citations

Nerve growth factor inhibits HCO3/- absorption in renal thick ascending limb through inhibition of basolateral membrane Na+/H+ exchange

Watts, B. A., George, T. & Good, D. W., Mar 19 1999, In : Journal of Biological Chemistry. 274, 12, p. 7841-7847 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
1998

Effect of long-term hyperosmolality on the NA+/H+ exchanger isoform NHE-3 in LLC-PK1 cells

Soleimani, M., Watts, B. A., Singh, G. & Good, D. W., Jan 1 1998, In : Kidney International. 53, 2, p. 423-431 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Hypertonicity activates MAP kinases and inhibits HCO3/- absorption via distinct pathways in thick ascending limb

Watts, B. A., Di Mari, J. F., Davis, R. J. & Good, D. W., Oct 1998, In : American Journal of Physiology - Renal Physiology. 275, 4 44-4, p. F478-F486

Research output: Contribution to journalArticle

24 Scopus citations
15 Scopus citations
1997

PKC isoforms in rat medullary thick ascending limb: Selective activation of the δ-isoform by PGE2

Aristimuño, P. C. & Good, D. W., May 1 1997, In : American Journal of Physiology - Renal Physiology. 272, 5 41-5, p. F624-F631

Research output: Contribution to journalArticle

35 Scopus citations
1996

Functional roles of apical membrane Na+/H+ exchange in rat medullary thick ascending limb

Good, D. W. & Watts, B. A., Jan 1 1996, In : American Journal of Physiology. 270, 4 PART 2, p. F691-F699

Research output: Contribution to journalArticle

63 Scopus citations

PGE2 reverses AVP inhibition of HCO3- absorption in rat MTAL by activation of protein kinase C

Good, D. W., Jan 1 1996, In : American Journal of Physiology. 270, 6 PART 2, p. F978-F985

Research output: Contribution to journalArticle

32 Scopus citations

Regulation of HCO3- absorption by prostaglandin E2 and G proteins in rat medullary thick ascending limb

Good, D. W. & George, T., Dec 1 1996, In : American Journal of Physiology. 270, 5 PART 2, p. F711-F717

Research output: Contribution to journalArticle

18 Scopus citations
1995
Open Access
48 Scopus citations
4 Scopus citations
37 Scopus citations

Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR

Good, D. W., Caflisch, C. R. & George, T., Jan 1 1995, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 269, 1 38-1, p. F47-F54

Research output: Contribution to journalArticle

9 Scopus citations
1994

Ammonium transport by the thick ascending limb of Henle's loop

Good, D. W., Jan 1 1994, In : Annual Review of Physiology. 56, p. 623-647 25 p.

Research output: Contribution to journalReview article

83 Scopus citations

Apical membrane Na+/H+ exchange in rat medullary thick ascending limb. pH(i)-dependence and inhibition by hyperosmolality

Watts, B. A. & Good, D. W., Jan 1 1994, In : Journal of Biological Chemistry. 269, 32, p. 20250-20255 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Effects of ammonium on intracellular pH in rat medullary thick ascending limb: Mechanisms of apical membrane NH4+ transport

Watts, B. A. & Good, D. W., May 1 1994, In : Journal of General Physiology. 103, 5, p. 917-936 20 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations
1993

The thick ascending limb as a site of renal bicarbonate reabsorption

Good, D. W., Jan 1 1993, In : Seminars in Nephrology. 13, 2, p. 225-235 11 p.

Research output: Contribution to journalReview article

76 Scopus citations
1992

Chronic hyperkalemia impairs ammonium transport and accumulation in the inner medulla of the rat

DuBose, T. D. & Good, D. W., Jan 1 1992, In : Journal of Clinical Investigation. 90, 4, p. 1443-1449 7 p.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations

Effects of adenosine on ion transport in rat medullary thick ascending limb

Beach, R. E. & Good, D. W., Jan 1 1992, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 263, 3 32-3, p. F482-F487

Research output: Contribution to journalArticle

56 Scopus citations

Effects of osmolality on bicarbonate absorption by medullary thick ascending limb of the rat

Good, D. W., Jan 1 1992, In : Journal of Clinical Investigation. 89, 1, p. 184-190 7 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
1991

Ammonium transport in the kidney: New physiological concepts and their clinical implications

DuBose, T. D., Good, D. W., Hamm, L. L. & Wall, S. M., May 1991, In : Journal of the American Society of Nephrology. 1, 11, p. 1193-1203 11 p.

Research output: Contribution to journalArticle

81 Scopus citations
18 Scopus citations

Effects of graded oxygen tension on adenosine release by renal medullary and thick ascending limb suspensions

Beach, R. E., Watts, B. A., Good, D. W., Benedict, C. R. & DuBose, T. D., May 1991, In : Kidney International. 39, 5, p. 836-842 7 p.

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Regulation of bicarbonate and ammonium absorption in the thick ascending limb of the rat

Good, D. W., Jan 1 1991, In : Kidney International. 40, SUPPL. 33, p. S-36-S-42

Research output: Contribution to journalArticle

6 Scopus citations