Erik Rytting, PhD, MS

Director, Nanomedicine Laboratory

  • 1427 Citations
  • 20 h-Index
20042020

Research output per year

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Research Output

  • 1427 Citations
  • 20 h-Index
  • 40 Article
  • 13 Comment/debate
  • 3 Chapter
  • 1 Review article
Article
8 Scopus citations

A Quantitative Structure-Property Relationship for Predicting Drug Solubility in PEG 400/Water Cosolvent Systems

Rytting, E., Lentz, K. A., Chen, X. Q., Qian, F. & Venkatesh, S., Feb 1 2004, In : Pharmaceutical Research. 21, 2, p. 237-244 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Aqueous and cosolvent solubility data for drug-like organic compounds

Rytting, E., Lentz, K. A., Chen, X. Q., Qian, F. & Venkatesh, S., Apr 26 2005, In : AAPS Journal. 7, 1, p. E78-E79 10.

Research output: Contribution to journalArticle

86 Scopus citations
38 Scopus citations

Charged nanoparticles as protein delivery systems: A feasibility study using lysozyme as model protein

Cai, C., Bakowsky, U., Rytting, E., Schaper, A. K. & Kissel, T., May 1 2008, In : European Journal of Pharmaceutics and Biopharmaceutics. 69, 1, p. 31-42 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

Contributions of phosphorylation to regulation of OCTN2 uptake of carnitine are minimal in BeWo cells

Rytting, E. & Audus, K. L., Feb 1 2008, In : Biochemical Pharmacology. 75, 3, p. 745-751 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Effect of CYP2C9 Polymorphisms on the Pharmacokinetics of Indomethacin During Pregnancy

Shah, M., Xu, M., Shah, P., Wang, X-M., Clark, S., Costantine, M., West, H. A., Nanovskaya, T., Ahmed, M., Abdel-Rahman, S., Venkataramanan, R., Caritis, S. N., Hankins, G. & Rytting, E., Jan 1 2018, (Accepted/In press) In : European Journal of Drug Metabolism and Pharmacokinetics.

Research output: Contribution to journalArticle

1 Scopus citations

Effects of low oxygen levels on the expression and function of transporter OCTN2 in BeWo cells

Rytting, E. & Audus, K. L., Aug 1 2007, In : Journal of Pharmacy and Pharmacology. 59, 8, p. 1095-1102 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Efficacy of novel highly specific bromodomain-containing protein 4 inhibitors in innate inflammation–driven airway remodeling

Tian, B., Liu, Z., Litvinov, J., Maroto, R., Jamaluddin, M., Rytting, E., Patrikeev, I., Ochoa, L., Vargas, G., Motamedi, M., Ameredes, B., Zhou, J. & Brasier, A. R., Jan 1 2019, In : American Journal of Respiratory Cell and Molecular Biology. 60, 1, p. 68-83 16 p.

Research output: Contribution to journalArticle

7 Scopus citations

Exploring the interactions of nanoparticles with multiple models of the maternal - Fetal interface

Rytting, E., May 1 2015, In : Nanotoxicology. 9, S1, p. 137-138 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

HPLC method development for quantification of doxorubicin in cell culture and placental perfusion media

Shah, M., Bourner, L., Ali, S., Al-Enazy, S., Youssef, M. M., Fisler, M. & Rytting, E., Mar 1 2018, In : Separations. 5, 1, 9.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Influence of morphology and drug distribution on the release process of FITC-dextran-loaded microspheres prepared with different types of PLGA

Cai, C., Mao, S., Germershaus, O., Schaper, A., Rytting, E., Chen, D. & Kissel, T., Jun 1 2009, In : Journal of Microencapsulation. 26, 4, p. 334-345 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Influence of particle size and material properties on mucociliary clearance from the airways

Henning, A., Schneider, M., Nafee, N., Muijs, L., Rytting, E., Wang, X., Kissel, T., Grafahrend, D., Klee, D. & Lehr, C. M., Aug 1 2010, In : Journal of Aerosol Medicine and Pulmonary Drug Delivery. 23, 4, p. 233-241 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

Influences of nanomaterials on the barrier function of epithelial cells

Ali, S. & Rytting, E., Jan 1 2014, In : Advances in experimental medicine and biology. 811, p. 45-54 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles

Rytting, E., Bur, M., Cartier, R., Bouyssou, T., Wang, X., Krüger, M., Lehr, C. M. & Kissel, T., Jan 4 2010, In : Journal of Controlled Release. 141, 1, p. 101-107 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

In vitro models for studying trophoblast transcellular transport.

Bode, C. J., Jin, H., Rytting, E., Silverstein, P. S., Young, A. M. & Audus, K. L., 2006, In : Methods in molecular medicine. 122, p. 225-239 15 p.

Research output: Contribution to journalArticle

77 Scopus citations

In vitro placental model optimization for nanoparticle transport studies

Cartwright, L., Poulsen, M. S., Nielsen, H. M., Pojana, G., Knudsen, L. E., Saunders, M. & Rytting, E., Feb 10 2012, In : International Journal of Nanomedicine. 7, p. 497-510 14 p.

Research output: Contribution to journalArticle

57 Scopus citations

Kinetics of silica nanoparticles in the human placenta

Poulsen, M. S., Mose, T., Maroun, L. L., Mathiesen, L., Knudsen, L. E. & Rytting, E., May 1 2015, In : Nanotoxicology. 9, S1, p. 79-86 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Low-affinity uptake of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (4-Di-1-ASP) in BeWo cells

Rytting, E., Bryan, J., Southard, M. & Audus, K. L., Mar 15 2007, In : Biochemical Pharmacology. 73, 6, p. 891-900 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Metabolism and disposition of bupropion in pregnant baboons (Papio cynocephalus)

Rytting, E., Wang, X., Vernikovskaya, D. I., Zhan, Y., Bauer, C., Abdel-Rahman, S. M., Ahmed, M. S. & Nanovskaya, T. N., Oct 1 2014, In : Drug Metabolism and Disposition. 42, 10, p. 1773-1779 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Modeling placental transport: Correlation of in vitro BeWo cell permeability and ex vivo human placental perfusion

Poulsen, M. S., Rytting, E., Mose, T. & Knudsen, L. E., Oct 1 2009, In : Toxicology in Vitro. 23, 7, p. 1380-1386 7 p.

Research output: Contribution to journalArticle

72 Scopus citations

Modelling of human transplacental transport as performed in Copenhagen, Denmark

Mathiesen, L., Mørck, T. A., Zuri, G., Andersen, M. H., Pehrson, C., Frederiksen, M., Mose, T., Rytting, E., Poulsen, M. S., Nielsen, J. K. & Knudsen, L. E., Jul 2014, In : Basic and Clinical Pharmacology and Toxicology. 115, 1, p. 93-100 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling

Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W. J., Sur, S. & Brasier, A. R., Apr 2019, In : Journal of Allergy and Clinical Immunology. 143, 4, p. 1380-1394.e9

Research output: Contribution to journalArticle

7 Scopus citations

Nanomedicine for uterine leiomyoma therapy

Ali, H., Kilic, G., Vincent, K., Motamedi, M. & Rytting, E., Feb 1 2013, In : Therapeutic Delivery. 4, 2, p. 161-175 15 p.

Research output: Contribution to journalArticle

12 Scopus citations
26 Scopus citations
34 Scopus citations

Pharmacokinetics of bupropion and its pharmacologically active metabolites in pregnancy

Fokina, V. M., Xu, M., Rytting, E., Abdel-Rahman, S. Z., West, H., Oncken, C., Clark, S. M., Ahmed, M. S., Hankins, G. D. V. & Nanovskaya, T. N., Jan 1 2016, In : Drug Metabolism and Disposition. 44, 11, p. 1832-1838 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Pharmacokinetics of indomethacin in pregnancy

Rytting, E., Nanovskaya, T. N., Wang, X., Vernikovskaya, D. I., Clark, S. M., Cochran, M., Abdel-Rahman, S. M., Venkataramanan, R., Caritis, S. N., Hankins, G. D. V. & Ahmed, M. S., Jun 2014, In : Clinical Pharmacokinetics. 53, 6, p. 545-551 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pharmacokinetics of metoprolol during pregnancy and lactation

Ryu, R. J., Eyal, S., Easterling, T. R., Caritis, S. N., Venkataraman, R., Hankins, G., Rytting, E., Thummel, K., Kelly, E. J., Risler, L., Phillips, B., Honaker, M. T., Shen, D. D. & Hebert, M. F., May 1 2016, In : Journal of Clinical Pharmacology. 56, 5, p. 581-589 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Placental control of drug delivery

Al-Enazy, S., Ali, S., Albekairi, N., El-Tawil, M. & Rytting, E., Jun 14 2016, (Accepted/In press) In : Advanced Drug Delivery Reviews.

Research output: Contribution to journalArticle

13 Scopus citations

Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development

Ilekis, J. V., Tsilou, E., Fisher, S., Abrahams, V. M., Soares, M. J., Cross, J. C., Zamudio, S., Illsley, N. P., Myatt, L., Colvis, C., Costantine, M., Haas, D. M., Sadovsky, Y., Weiner, C., Rytting, E. & Bidwell, G., Jul 1 2016, In : American Journal of Obstetrics and Gynecology. 215, 1, p. S1-S46

Research output: Contribution to journalArticle

84 Scopus citations

Placental transport and in vitro effects of Bisphenol A

Mørck, T. J., Sorda, G., Bechi, N., Rasmussen, B. S., Nielsen, J. B., Ietta, F., Rytting, E., Mathiesen, L., Paulesu, L. & Knudsen, L. E., Aug 1 2010, In : Reproductive Toxicology. 30, 1, p. 131-137 7 p.

Research output: Contribution to journalArticle

115 Scopus citations
49 Scopus citations

Preparation of nanoparticles by solvent displacement for drug delivery: A shift in the " ouzo region" upon drug loading

Beck-Broichsitter, M., Rytting, E., Lebhardt, T., Wang, X. & Kissel, T., Oct 1 2010, In : European Journal of Pharmaceutical Sciences. 41, 2, p. 244-253 10 p.

Research output: Contribution to journalArticle

108 Scopus citations
3 Scopus citations

Selective Antagonists of the Bronchiolar Epithelial NF-κB-Bromodomain-Containing Protein 4 Pathway in Viral-Induced Airway Inflammation

Tian, B., Liu, Z., Yang, J., Sun, H., Zhao, Y., Wakamiya, M., Chen, H., Rytting, E., Zhou, J. & Brasier, A. R., Apr 24 2018, In : Cell Reports. 23, 4, p. 1138-1151 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Small Molecule Neuromedin U Receptor 2 Agonists Suppress Food Intake and Decrease Visceral Fat in Animal Models.

Sampson, C. M., Kasper, J., Felsing, D., Raval, S., Ye, N., P, W., Rytting, E., Zhou, J., Allen, J. & Hommel, J., Aug 23 2018, In : Pharmacology Research and Perspectives. 6, (5):e00425. , doi: 10.1002/prp2.425.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Transport of benzo[α]pyrene in the dually perfused human placenta perfusion model: Effect of albumin in the perfusion medium

Mathiesen, L., Rytting, E., Mose, T. & Knudsen, L. E., Sep 1 2009, In : Basic and Clinical Pharmacology and Toxicology. 105, 3, p. 181-187 7 p.

Research output: Contribution to journalArticle

42 Scopus citations

Transport of digoxin-loaded polymeric nanoparticles across BeWo cells, an in vitro model of human placental trophoblast

Albekairi, N. A., Al-Enazy, S., Ali, S. & Rytting, E., Dec 1 2015, In : Therapeutic Delivery. 6, 12, p. 1325-1334 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
Chapter

Cell Culture Models for Drug Transport Studies

Karunaratne, D. N., Silverstein, P. S., Vasandani, V., Young, A. M., Rytting, E., Yops, B. & Audus, K. L., May 13 2005, Drug Delivery: Principles and Applications. John Wiley & Sons, Inc., p. 103-124 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Cell Culture Models for Drug Transport Studies

Kalashnikova, I., Albekairi, N., Ali, S., Al Enazy, S. & Rytting, E., Mar 25 2016, Drug Delivery: Principles and Applications: Second Edition. wiley, p. 131-151 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Fetal Drug Therapy

Rytting, E. & Ahmed, M. S., Aug 27 2013, Clinical Pharmacology During Pregnancy. Elsevier Inc., p. 55-72 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations
Comment/debate

Cleaning up the clutter

Rytting, E., Mar 16 2011, In : Science Translational Medicine. 3, 74, 74ec36.

Research output: Contribution to journalComment/debate

Getting past the bullies

Rytting, E., Aug 10 2011, In : Science Translational Medicine. 3, 95, 95ec127.

Research output: Contribution to journalComment/debate

HIV: HIV gets a wake-up call

Rytting, E., May 11 2011, In : Science Translational Medicine. 3, 82, 82ec70.

Research output: Contribution to journalComment/debate

Just be "pH"-tient

Rytting, E., Jan 25 2012, In : Science Translational Medicine. 4, 118

Research output: Contribution to journalComment/debate

More than just "getting in"

Rytting, E., Sep 28 2011, In : Science Translational Medicine. 3, 102, 102ec159.

Research output: Contribution to journalComment/debate

Nanoparticles and jelly

Rytting, E., Apr 13 2011, In : Science Translational Medicine. 3, 78, 78ec52.

Research output: Contribution to journalComment/debate

Nanotechnology: Helping the heart to heal

Rytting, E., Oct 26 2011, In : Science Translational Medicine. 3, 106, 106ec174.

Research output: Contribution to journalComment/debate

1 Scopus citations