Photo of Filippa Lo Cascio

Filippa Lo Cascio

  • 47 Citations
  • 3 h-Index
20162018
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Fingerprint Dive into the research topics where Filippa Lo Cascio is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Poisons Medicine & Life Sciences
Oligomers Chemical Compounds
Oxadiazoles Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences
Histone Deacetylase Inhibitors Medicine & Life Sciences
Tauopathies Medicine & Life Sciences
Cell death Chemical Compounds
Neurofibrillary Tangles Medicine & Life Sciences

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Research Output 2016 2018

  • 47 Citations
  • 3 h-Index
  • 4 Article
  • 1 Chapter
6 Citations (Scopus)

Azure C Targets and Modulates Toxic Tau Oligomers

Lo Cascio, F. & Kayed, R., Jun 20 2018, In : ACS Chemical Neuroscience. 9, 6, p. 1317-1326 10 p.

Research output: Contribution to journalArticle

Poisons
Oligomers
Alzheimer Disease
Tauopathies
Pathology
2 Citations (Scopus)

Binding and neurotoxicity mitigation of toxic tau oligomers by synthetic heparin like oligosaccharides

Wang, P., Lo Cascio, F., Gao, J., Kayed, R. & Huang, X., Jan 1 2018, In : Chemical Communications. 54, 72, p. 10120-10123 4 p.

Research output: Contribution to journalArticle

Oligosaccharides
Poisons
Oligomers
Heparin
Cytotoxicity
11 Citations (Scopus)

The dissociation of the Hsp60/pro-Caspase-3 complex by bis(pyridyl)oxadiazole copper complex (CubipyOXA) leads to cell death in NCI-H292 cancer cells

Caruso Bavisotto, C., Nikolic, D., Marino Gammazza, A., Barone, R., Lo Cascio, F., Mocciaro, E., Zummo, G., Conway de Macario, E., Macario, A. JL., Cappello, F., Giacalone, V., Pace, A., Barone, G., Palumbo Piccionello, A. & Campanella, C., May 1 2017, In : Journal of Inorganic Biochemistry. 170, p. 8-16 9 p.

Research output: Contribution to journalArticle

Oxadiazoles
Cell death
Caspase 3
Copper
Cell Death

The Potential of Small Molecules in Preventing Tau Oligomer Formation and Toxicity

Gerson, J. E., Lo Cascio, F. & Kayed, R., Jan 20 2017, Neuroprotection in Alzheimer's Disease. Elsevier Inc., p. 97-121 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Poisons
Amyloid
Neurodegenerative Diseases
Tauopathies
Amyloidogenic Proteins
28 Citations (Scopus)

The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells

Campanella, C., D'Anneo, A., Gammazza, A. M., Bavisotto, C. C., Barone, R., Emanuele, S., Lo Cascio, F., Mocciaro, E., Fais, S., De Macario, E. C., Macario, A. J. L., Cappello, F. & Lauricella, M., May 17 2016, In : Oncotarget. 7, 20, p. 28849-28867 19 p.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylase Inhibitors
Carcinoma
Lung
Post Translational Protein Processing
Neoplasms