Giulio Taglialatela, PhD

  • 3831 Citations
  • 36 h-Index
1987 …2024

Research output per year

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Research Output

2020

Amelioration of hippocampal dysfunction by adipose tissue-targeted stem cell transplantation in a mouse model of type 2 diabetes

Krishnan, B., Sallam, H. S., Tumurbataar, B., Saieva, S., Baymon, DM., Tuvdendorj, D., Micci, M. A., Abate, N. & Taglialatela, G., Apr 1 2020, In : Journal of neurochemistry. 153, 1, p. 51-62 12 p.

Research output: Contribution to journalArticle

Selected microRNAs Increase Synaptic Resilience to the Damaging Binding of the Alzheimer’s Disease Amyloid Beta Oligomers

Zolochevska, O. & Taglialatela, G., May 1 2020, In : Molecular Neurobiology. 57, 5, p. 2232-2243 12 p.

Research output: Contribution to journalArticle

Open Access
2019

Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues

Kulas, J. A., Franklin, W. F., Smith, N. A., Manocha, G. D., Puig, K. L., Nagamoto-Combs, K., Hendrix, R. D., Taglialatela, G., Barger, S. W. & Combs, C. K., Jan 1 2019, In : American journal of physiology. Endocrinology and metabolism. 316, 1, p. E106-E120

Research output: Contribution to journalArticle

4 Scopus citations
Open Access

Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway

Shah, S. Z. A., Zhao, D., Taglialatela, G., Hussain, T., Dong, H., Sabir, N., Mangi, M. H., Wu, W., Lai, M., Zhang, X., Duan, Y., Wang, L., Zhou, X. & Yang, L., Mar 6 2019, In : International journal of molecular sciences. 20, 5

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Corrigendum: Ablation of amyloid precursor protein increases insulin-degrading enzyme levels and activity in brain and peripheral tissues (Am J Physiol Endocrinol Metab, (2019) 316, (E106-E120), 10.1152/ajpendo.00279.2018)

Kulas, J. A., Franklin, W. F., Smith, N. A., Manocha, G. D., Puig, K. L., Nagamoto-Combs, K., Hendrix, R. D., Taglialatela, G., Barger, S. W. & Combs, C. K., Feb 1 2019, In : American Journal of Physiology - Endocrinology and Metabolism. 316, 2, p. E345

Research output: Contribution to journalComment/debate

Hippocampal stem cells promotes synaptic resistance to the dysfunctional impact of amyloid beta oligomers via secreted exosomes

Micci, M. A., Krishnan, B., Bishop, E., Zhang, W. R., Guptarak, J., Grant, A., Zolochevska, O., Tumurbaatar, B., Franklin, W., Marino, C., Widen, S. G., Luthra, A., Kernie, S. G. & Taglialatela, G., Jun 14 2019, In : Molecular Neurodegeneration. 14, 1, 25.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
1 Scopus citations

Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies

Comerota, M. M., Tumurbaatar, B., Krishnan, B., Kayed, R. & Taglialatela, G., May 1 2019, In : Molecular Neurobiology. 56, 5, p. 3341-3355 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Suppressing aberrant phospholipase D1 signaling in 3xTg Alzheimer’s disease mouse model promotes synaptic resilience

Bourne, K. Z., Natarajan, C., Perez, C. X. M., Tumurbaatar, B., Taglialatela, G. & Krishnan, B., Dec 1 2019, In : Scientific reports. 9, 1, 18342.

Research output: Contribution to journalArticle

Open Access
2018
9 Scopus citations

Postsynaptic Proteome of Non-Demented Individuals with Alzheimer's Disease Neuropathology

Cain, O., Bjorklund, N., Woltjer, R., Wiktorowicz, J. E. & Taglialatela, G., Jan 1 2018, In : Journal of Alzheimer's disease : JAD. 65, 2, p. 659-682 24 p.

Research output: Contribution to journalArticle

7 Scopus citations
2017

Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters

Shah, S. Z. A., Zhao, D., Taglialatela, G., Khan, S. H., Hussain, T., Dong, H., Lai, M., Zhou, X. & Yang, L., Jan 12 2017, (Accepted/In press) In : Neurotherapeutics. p. 1-21 21 p.

Research output: Contribution to journalArticle

11 Scopus citations

Near infrared light decreases synaptic vulnerability to amyloid beta oligomers

Comerota, M. M., Krishnan, B. & Taglialatela, G., Dec 1 2017, In : Scientific Reports. 7, 1, 15012.

Research output: Contribution to journalArticle

10 Scopus citations

PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease

Hsu, W. C. J., Wildburger, N. C., Haidacher, S. J., Nenov, M. N., Folorunso, O., Singh, A. K., Chesson, B. C., Franklin, W. F., Cortez, I., Sadygov, R., Dineley, K., Rudra, J. S., Taglialatela, G., Lichti, C. F., Denner, L. & Laezza, F., Sep 1 2017, In : Experimental Neurology. 295, p. 1-17 17 p.

Research output: Contribution to journalArticle

16 Scopus citations
2016

A method to determine insulin responsiveness in synaptosomes isolated from frozen brain tissue

Franklin, W. & Taglialatela, G., Mar 1 2016, In : Journal of Neuroscience Methods. 261, p. 128-134 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
9 Scopus citations

NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies

Ali, Y. O., Allen, H. M., Yu, L., Li-Kroeger, D., Bakhshizadehmahmoudi, D., Hatcher, A., McCabe, C., Xu, J., Bjorklund, N., Taglialatela, G., Bennett, D. A., De Jager, P. L., Shulman, J. M., Bellen, H. J. & Lu, H. C., Jun 2 2016, In : PLoS Biology. 14, 6, e1002472.

Research output: Contribution to journalArticle

42 Scopus citations
9 Scopus citations

Overexpression of heat shock factor 1 maintains TAR DNA binding protein 43 solubility via induction of inducible heat shock protein 70 in cultured cells

Lin, P. Y., Folorunso, O., Taglialatela, G. & Pierce, A., Jul 1 2016, In : Journal of Neuroscience Research. 94, 7, p. 671-682 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Preserved neurogenesis in non-demented individuals with AD neuropathology

Briley, D., Ghirardi, V., Woltjer, R., Renck, A., Cain, O., Taglialatela, G. & Micci, M., Jun 14 2016, In : Scientific Reports. 6, 27812.

Research output: Contribution to journalArticle

21 Scopus citations

The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice

Puig, K. L., Kulas, J. A., Franklin, W., Rakoczy, S. G., Taglialatela, G., Brown-Borg, H. M. & Combs, C. K., Apr 1 2016, In : Neurobiology of Aging. 40, p. 22-40 19 p.

Research output: Contribution to journalArticle

10 Scopus citations
2015

Inflammatory risk factors and pathologies promoting Alzheimer’s disease progression: Is RAGE the key?

Matrone, C., Djelloul, M., Taglialatela, G. & Perrone, L., Jan 1 2015, In : Histology and histopathology. 30, 2, p. 125-139 15 p.

Research output: Contribution to journalReview article

27 Scopus citations

NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer's Disease

Lian, H., Yang, L., Cole, A., Sun, L., Chiang, A. C. A., Fowler, S. W., Shim, D. J., Rodriguez-Rivera, J., Taglialatela, G., Jankowsky, J. L., Lu, H. C. & Zheng, H., Jan 7 2015, In : Neuron. 85, 1, p. 101-115 15 p.

Research output: Contribution to journalArticle

139 Scopus citations

Oxidative stress events and neuronal dysfunction in alzheimer’s disease: Focus on APE1/ref-1-mediated survival strategies

Kaur, N., Sarkar, B., Mittal, S., Dhiman, M., Taglialatela, G., Perez-Polo, R. J. & Mantha, A. K., Jan 1 2015, Free Radicals in Human Health and Disease. Springer India, p. 175-207 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Peripheral adipose tissue insulin resistance alters lipid composition and function of hippocampal synapses

Sallam, H. S., Tumurbaatar, B., Zhang, W. R., Tuvdendorj, D., Chandalia, M., Tempia, F., Laezza, F., Taglialatela, G. & Abate, N., Apr 2015, In : Journal of neurochemistry. 133, 1, p. 125-133 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Reduced Incidence of Dementia in Solid Organ Transplant Patients Treated with Calcineurin Inhibitors

Taglialatela, G., Rastellini, C. & Cicalese, L., Jul 24 2015, In : Journal of Alzheimer's Disease. 47, 2, p. 329-333 5 p.

Research output: Contribution to journalArticle

19 Scopus citations
2012
41 Scopus citations

Brain serum amyloid P levels are reduced in individuals that lack Dementia while having Alzheimer's disease neuropathology

Crawford, J. R., Gomer, R. H., Bjorklund, N. L. & Taglialatela, G., Apr 1 2012, In : Neurochemical Research. 37, 4, p. 795-801 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Potential role of α-synuclein in neurodegeneration: Studies in a rat animal model

Stoica, G., Lungu, G., Bjorklund, N. L., Taglialatela, G., Zhang, X., Chiu, V., Hill, H. H., Schenk, J. O. & Murray, I., Aug 1 2012, In : Journal of neurochemistry. 122, 4, p. 812-822 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Proteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interaction

Mantha, A. K., Dhiman, M., Taglialatela, G., Perez-Polo, R. J. & Mitra, S., Jun 1 2012, In : Journal of Neuroscience Research. 90, 6, p. 1230-1239 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
28 Scopus citations

α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: Relevance to human synucleopathic diseases

Martin, Z. S., Neugebauer, V., Dineley, K. T., Kayed, R., Zhang, W., Reese, L. C. & Taglialatela, G., Feb 1 2012, In : Journal of neurochemistry. 120, 3, p. 440-452 13 p.

Research output: Contribution to journalArticle

56 Scopus citations
2011

A role for calcineurin in Alzheimer's disease

Reese, L. C. & Taglialatela, G., Dec 1 2011, In : Current Neuropharmacology. 9, 4, p. 685-692 8 p.

Research output: Contribution to journalReview article

54 Scopus citations
52 Scopus citations
2010

Amyloid-β oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice

Dineley, K. T., Kayed, R., Neugebauer, V., Fu, Y., Zhang, W., Reese, L. C. & Taglialatela, G., Oct 1 2010, In : Journal of Neuroscience Research. 88, 13, p. 2923-2932 10 p.

Research output: Contribution to journalArticle

74 Scopus citations
23 Scopus citations

Calcineurin inhibition at the clinical phase of prion disease reduces neurodegeneration, improves behavioral alterations and increases animal survival

Mukherjee, A., Morales-Scheihing, D., Gonzalez-Romero, D., Green, K., Taglialatela, G. & Soto, C., Oct 1 2010, In : PLoS pathogens. 6, 10, e1001138.

Research output: Contribution to journalArticle

33 Scopus citations

Neuroimmunomodulation by calcineurin in aging and Alzheimer's disease

Reese, L. C. & Taglialatela, G., Jan 1 2010, In : Aging and Disease. 1, 3, p. 245-253 9 p.

Research output: Contribution to journalReview article

11 Scopus citations
2009

Genome-Wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells

Vascotto, C., Cesaratto, L., Zeef, L. A. H., Deganuto, M., Dambrosio, C., Scaloni, A., Romanello, M., Damante, G., Taglialatela, G., Delneri, D., Kelley, M. R., Mitra, S., Quadrifoglio, F. & Tell, G., Feb 1 2009, In : Proteomics. 9, 4, p. 1058-1074 17 p.

Research output: Contribution to journalArticle

68 Scopus citations

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

Taglialatela, G., Hogan, D., Zhang, W. R. & Dineley, K. T., Jun 8 2009, In : Behavioural Brain Research. 200, 1, p. 95-99 5 p.

Research output: Contribution to journalArticle

138 Scopus citations
2008

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

Reese, L. C., Zhang, W. R., Dineley, K. T., Kayed, R. & Taglialatela, G., Dec 3 2008, In : Aging cell. 7, 6, p. 824-835 12 p.

Research output: Contribution to journalArticle

68 Scopus citations
2007

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice

Dineley, K. T., Hogan, D., Zhang, W. R. & Taglialatela, G., Sep 1 2007, In : Neurobiology of Learning and Memory. 88, 2, p. 217-224 8 p.

Research output: Contribution to journalArticle

105 Scopus citations

Up-regulation of Bcl-2 in APP transgenic mice is associated with neuroprotection

Karlnoski, R., Wilcock, D., Dickey, C., Ronan, V., Gordon, M. N., Zhang, W., Morgan, D. & Taglialatela, G., Jan 1 2007, In : Neurobiology of Disease. 25, 1, p. 179-188 10 p.

Research output: Contribution to journalArticle

22 Scopus citations
2006

Bcl-2 localized at the nuclear compartment induces apoptosis after transient overexpression

Portier, B. P. & Taglialatela, G., Dec 29 2006, In : Journal of Biological Chemistry. 281, 52, p. 40493-40502 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Rapid assay for quantitative measurement of apoptosis in cultured cells and brain tissue

Portier, B. P., Ferrari, D. C. & Taglialatela, G., Jul 15 2006, In : Journal of Neuroscience Methods. 155, 1, p. 134-142 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Suppression of nNOS expression in rat enteric neurones by the receptor for advanced glycation end-products

Korenaga, K., Micci, M. A., Taglialatela, G. & Pasricha, P. J., May 1 2006, In : Neurogastroenterology and Motility. 18, 5, p. 392-400 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
2005

Proton-sensing G protein-coupled receptor mobilizes calcium in human synovial cells

Christensen, B. N., Kochukov, M., McNearney, T. A., Taglialatela, G. & Westlund, K. N., Sep 2005, In : American Journal of Physiology - Cell Physiology. 289, 3 58-3, p. C601-C608

Research output: Contribution to journalArticle

19 Scopus citations
6 Scopus citations