Projects per year
Personal profile
Research Strategic Pillar
Dr. Randall Urban, VP and Chief Research Officer, has determined that UTMB research should be prioritized into six health communities. This researcher has received the following badge(s):
Personal profile
Member, Institute for Human Infections & Immunity
Research interests
Division: Vaccinology
Dr. Milligan is a Professor of Pediatrics and Senior Scientist with the Sealy Center for Vaccine Development. He received both his B.S. and M.S. in Biology from Emporia State University in Emporia, Kansas and his PhD in Microbiology from the University of Missouri-Columbia. He completed his postdoctoral fellowship in viral immunology at Washington University School of Medicine in St. Louis, Missouri. He has over twenty years of experience in characterizing immune responses to virus infections in animal models.? The primary focus of his laboratory is to investigate the protective role of B and T lymphocytes against HSV infection of the genital tract, sensory ganglia, and central nervous systems.?? His laboratory also studies how interactions between virus vaccines and the innate immune system shape the adaptive immune response.
Research Strategic Pillar Keywords
- Infectious/ Immunological Health
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Collaborations and top research areas from the last five years
Projects
- 12 Completed
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Cervicovaginal Vaccine Delivery by Novel Pod Intravaginal Rings for Therapeutic Immunization Against HSV-2
5/25/20 → 4/30/23
Project: Other project
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Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates
Goethals, O., Kaptein, S. J. F., Kesteleyn, B., Bonfanti, J. F., Van Wesenbeeck, L., Bardiot, D., Verschoor, E. J., Verstrepen, B. E., Fagrouch, Z., Putnak, J. R., Kiemel, D., Ackaert, O., Straetemans, R., Lachau-Durand, S., Geluykens, P., Crabbe, M., Thys, K., Stoops, B., Lenz, O., Tambuyzer, L., & 24 others , Mar 23 2023, In: Nature. 615, 7953, p. 678-686 9 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Boosting of vaginal HSV-2-specific B and T cell responses by intravaginal therapeutic immunization results in diminished recurrent HSV-2 disease
Bourne, N., Keith, C. A., Miller, A. L., Pyles, R. B., Cohen, G. & Milligan, G. N., Sep 2023, In: Journal of virology. 97, 9Research output: Contribution to journal › Article › peer-review
Open Access -
Impact of CD4+ T lymphocytes on the cellular and molecular milieu of the vaginal mucosa following HSV-2 challenge of immune guinea pigs
Bourne, N., Keith, C. A., Miller, A. L., Pyles, R. B. & Milligan, G. N., Nov 2023, In: Virology. 588, 109907.Research output: Contribution to journal › Article › peer-review
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Baseline mapping of Oropouche virology, epidemiology, therapeutics, and vaccine research and development
Files, M. A., Hansen, C. A., Herrera, V. C., Schindewolf, C., Barrett, A. D. T., Beasley, D. W. C., Bourne, N. & Milligan, G. N., Dec 2022, In: npj Vaccines. 7, 1, 38.Research output: Contribution to journal › Review article › peer-review
Open Access11 Scopus citations -
Characterization of the Ovine Vaginal Microbiome and Inflammation Patterns as an Improved Testing Model of Human Vaginal Irritation
Pyles, R. B., Miller, A. L., Maxwell, C., Dawson, L., Richardson-Harman, N., Swartz, G., O'Neill, C., Walker, C., Milligan, G. N., Madsen, T., Motamedi, M., Vargas, G. & Vincent, K. L., 2021, In: Frontiers in Reproductive Health. 3, 714829.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations