• 1699 Citations
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1985 …2020

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2019
Open Access

Defining a correlate of protection for chikungunya virus vaccines

Milligan, G. N., Schnierle, B. S., McAuley, A. J. & Beasley, D. W. C., Nov 28 2019, In : Vaccine. 37, 50, p. 7427-7436 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo

Banasik, B. N., Perry, C. L., Keith, C. A., Bourne, N., Schäfer, H. & Milligan, G. N., Nov 2019, In : Journal of Immunological Methods. 474, 112654.

Research output: Contribution to journalArticle

Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2

Bourne, N., Banasik, B. N., Perry, C. L., Miller, A. L., White, M., Pyles, R. & Milligan, G., Jan 2 2019, In : Virology. 526, p. 180-188 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Increased frequency of virus shedding by herpes simplex virus 2-infected Guinea pigs in the absence of CD4 T lymphocytes

Bourne, N., Perry, C. L., Banasik, B. N., Miller, A. L., White, M., Pyles, R., Schäfer, H. & Milligan, G., Feb 1 2019, In : Journal of Virology. 93, 4, e0172118.

Research output: Contribution to journalArticle

2 Scopus citations
2018

A combined carrier-adjuvant system of peptide nanofibers and toll-like receptor agonists potentiates robust CD8+ T cell responses

Rudra, J. S., Banasik, B. N. & Milligan, G. N., Jan 25 2018, In : Vaccine. 36, 4, p. 438-441 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development review-article

Hallam, H. J., Hallam, S., Rodriguez, S., Barrett, A., Beasley, D., Chua, A., Ksiazek, T., Milligan, G., Sathiyamoorthy, V. & Reece, L. M., Dec 1 2018, In : npj Vaccines. 3, 1, 11.

Research output: Contribution to journalArticle

28 Scopus citations

Characterization of a murine model of non-lethal, symptomatic dengue virus infection

Sarathy, V., White, M., Li, L., Kaiser, J. A., Campbell, G., Milligan, G., Bourne, N. & Barrett, A., Dec 1 2018, In : Scientific Reports. 8, 1, 4900.

Research output: Contribution to journalArticle

6 Scopus citations
3 Scopus citations

Transcriptional Analysis of the Guinea Pig Mucosal Immune Response to Intravaginal Infection with Herpes Simplex Virus Type 2

Veselenak, R. L., Milligan, G., Miller, A. L., Pyles, R. & Bourne, N., May 1 2018, In : Virology. 518, p. 349-357 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

A lethal model of disseminated dengue virus type 1 infection in AG129 mice

Milligan, G., Sarathy, V., White, M. M., Greenberg, M. B., Campbell, G., Pyles, R., Barrett, A. & Bourne, N., Oct 1 2017, In : Journal of General Virology. 98, 10, p. 2507-2519 13 p., 000923.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Detection of herpes simplex virus type 2 (HSV-2) -specific cell-mediated immune responses in guinea pigs during latent HSV-2 genital infection

Perry, C. L., Banasik, B. N., Gorder, S. R., Xia, J., Auclair, S., Bourne, N. & Milligan, G., Dec 1 2016, In : Journal of Immunological Methods. 439, p. 1-7 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Dysregulation of toll-like receptor 7 compromises innate and adaptive T cell responses and host resistance to an attenuated West Nile virus infection in old mice

Xie, G., Luo, H., Pang, L., Peng, B., Winkelmann, E., McGruder, B., Hesse, J., Whiteman, M., Campbell, G., Milligan, G., Cong, Y., Barrett, A. & Wang, T., 2016, In : Journal of Virology. 90, 3, p. 1333-1344 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

In vivo rectal mucosal barrier function imaging in a large-animal model by using confocal endomicroscopy: Implications for injury assessment and use in HIV prevention studies

Vargas, G., Vincent, K., Zhu, Y., Szafron, D., Brown, T. C., Villarreal, P. P., Bourne, N., Milligan, G. & Motamedib, M., Aug 1 2016, In : Antimicrobial Agents and Chemotherapy. 60, 8, p. 4600-4609 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Status of vaccine research and development of vaccines for Nipah virus

Satterfield, B. A., Dawes, B. E. & Milligan, G., Jun 3 2016, In : Vaccine. 34, 26, p. 2971-2975 5 p.

Research output: Contribution to journalArticle

37 Scopus citations
2015

A dengue virus type 4 model of disseminated lethal infection in AG129 mice

Milligan, G., Sarathy, V., Infante, E., Li, L., Campbell, G., Beatty, P. R., Harris, E., Barrett, A. & Bourne, N., May 4 2015, In : PLoS One. 10, 5, e0125476.

Research output: Contribution to journalArticle

29 Scopus citations
38 Scopus citations
14 Scopus citations

Mouse models of dengue virus infection for vaccine testing

Sarathy, V., Milligan, G., Bourne, N. & Barrett, A., Dec 10 2015, In : Vaccine. 33, 50, p. 7051-7060 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
2014
7 Scopus citations

Investigating the efficacy of monovalent and tetravalent dengue vaccine formulations against DENV-4 challenge in AG129 mice

Fuchs, J., Chu, H., O'Day, P., Pyles, R., Bourne, N., Das, S. C., Milligan, G. N., Barrett, A. D. T., Partidos, C. D. & Osorio, J. E., Nov 12 2014, In : Vaccine. 32, 48, p. 6537-6543 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Subcapsular sinus macrophages limit dissemination of West Nile virus particles after inoculation but are not essential for the development of West Nile virus-specific T cell responses

Winkelmann, E. R., Widman, D. G., Xia, J., Johnson, A. J., van Rooijen, N., Mason, P. W., Bourne, N. & Milligan, G. N., Feb 1 2014, In : Virology. 450-451, p. 278-289 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Virus-specific immune memory at peripheral sites of Herpes Simplex Virus type 2 (HSV-2) infection in Guinea pigs

Xia, J., Veselenak, R. L., Gorder, S. R., Bourne, N. & Milligan, G. N., Dec 8 2014, In : PloS one. 9, 12, e114652.

Research output: Contribution to journalArticle

9 Scopus citations
2013
16 Scopus citations
2012

Influence of methamphetamine on genital herpes simplex virus type 2 infection in a mouse model

Valencia, F., Bubar, M. J., Milligan, G., Cunningham, K. A. & Bourne, N., Sep 1 2012, In : Sexually Transmitted Diseases. 39, 9, p. 720-725 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling

Winkelmann, E. R., Widman, D. G., Xia, J., Ishikawa, T., Miller-Kittrell, M., Nelson, M. H., Bourne, N., Scholle, F., Mason, P. W. & Milligan, G. N., Feb 14 2012, In : Vaccine. 30, 8, p. 1465-1475 11 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Rapid clearance of herpes simplex virus type 2 by CD8+ T cells requires high level expression of effector T cell functions

Nelson, M. H., Bird, M. D., Chu, C. F., Johnson, A. J., Friedrich, B. M., Allman, W. R. & Milligan, G. N., Apr 1 2011, In : Journal of Reproductive Immunology. 89, 1, p. 10-17 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
2010

Benzalkonium chloride causes colposcopic changes and increased susceptibility to genital herpes infection in mice

Vincent, K. L., Bell, B. A., Johnston, R. K., Stegall, R., Vargas, G., Tan, A., Stanberry, L. R., Rosenthal, S. L., Milligan, G. N., Motamedi, M. & Bourne, N., Sep 1 2010, In : Sexually Transmitted Diseases. 37, 9, p. 579-584 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
10 Scopus citations

Immunogenicity of RepliVAX WN, a novel single-cycle West Nile virus vaccine

Nelson, M. H., Winkelmann, E., Ma, Y., Xia, J., Mason, P. W., Bourne, N. & Milligan, G. N., Dec 16 2010, In : Vaccine. 29, 2, p. 174-182 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2009

3,4-methylenedioxymethamphetamine increases susceptiblity to genital herpes simplex virus infection in mice

Pennock, J. W., Stegall, R., Bubar, M. J., Milligan, G., Cunningham, K. A. & Bourne, N., Oct 15 2009, In : Journal of Infectious Diseases. 200, 8, p. 1247-1250 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2

Yoshikawa, N., Yoshikawa, T., Hill, T., Huang, C., Watts, D. M., Makino, S., Milligan, G., Chan, T., Peters, C. J. & Tseng, C. T. K., Jun 1 2009, In : Journal of virology. 83, 11, p. 5451-5465 15 p.

Research output: Contribution to journalArticle

9 Scopus citations

Estradiol improves genital herpes vaccine efficacy in mice

Pennock, J. W., Stegall, R., Bell, B., Vargas, G., Motamedi, M., Milligan, G. & Bourne, N., Sep 25 2009, In : Vaccine. 27, 42, p. 5830-5836 7 p.

Research output: Contribution to journalArticle

23 Scopus citations
2008

Antibody-mediated protection against genital herpes simplex virus type 2 disease in mice by Fc gamma receptor-dependent and -independent mechanisms

Chu, C. F., Meador, M. G., Young, C. G., Strasser, J. E., Bourne, N. & Milligan, G. N., Jun 1 2008, In : Journal of Reproductive Immunology. 78, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Effector CD4+ T-cell involvement in clearance of infectious herpes simplex virus type 1 from sensory ganglia and spinal cords

Johnson, A. J., Chu, C. F. & Milligan, G. N., Oct 1 2008, In : Journal of virology. 82, 19, p. 9678-9688 11 p.

Research output: Contribution to journalArticle

49 Scopus citations

T lymphocytes contribute to antiviral immunity and pathogenesis in experimental human metapneumovirus infection

Kolli, D., Bataki, E. L., Spetch, L. A., Guerrero-Plata, A., Jewell, A. M., Piedra, P. A., Milligan, G. N., Garofalo, R. P. & Casola, A., Sep 1 2008, In : Journal of virology. 82, 17, p. 8560-8569 10 p.

Research output: Contribution to journalArticle

51 Scopus citations
2007

Early resolution of herpes simplex virus type 2 infection of the murine genital tract involves stimulation of genital parenchymal cells by gamma interferon

Bird, M. D., Chu, C. F., Johnson, A. J. & Milligan, G. N., Jan 1 2007, In : Journal of virology. 81, 1, p. 423-426 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
2005

A soluble divalent class I MHC/IgG1 fusion protein activates CD8+ T cells in vivo

Carey, B., DeLay, M., Strasser, J. E., Chalk, C., Dudley-McClain, K., Milligan, G. N., Brunner, H. I., Thornton, S. & Hirsch, R., Jul 1 2005, In : Clinical Immunology. 116, 1, p. 65-76 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Clearance of herpes simplex virus type 2 by CD8+ T cells requires gamma interferon and either perform- or Fas-mediated cytolytic mechanisms

Dobbs, M. E., Strasser, J. E., Chu, C. F., Chalk, C. & Milligan, G. N., Dec 1 2005, In : Journal of virology. 79, 23, p. 14546-14554 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

Effects of candidate vaginally-applied microbicide compounds on innate immune cells

Milligan, G. N., Young, C. G., Meador, M. G., Chu, C. F. & Stanberry, L. R., Aug 1 2005, In : Journal of Reproductive Immunology. 66, 2, p. 103-116 14 p.

Research output: Contribution to journalArticle

4 Scopus citations

Efficacy and toxicity of zinc salts as candidate topical microbicides against vaginal herpes simplex virus type 2 infection

Bourne, N., Stegall, R., Montano, R., Meador, M., Stanberry, L. R. & Milligan, G. N., Mar 1 2005, In : Antimicrobial agents and chemotherapy. 49, 3, p. 1181-1183 3 p.

Research output: Contribution to journalArticle

25 Scopus citations
90 Scopus citations
47 Scopus citations

Long-term presence of virus-specific plasma cells in sensory ganglia and spinal cord following intravaginal inoculation of herpes simplex virus type 2

Milligan, G. N., Meador, M. G., Chu, C. F., Young, C. G., Martin, T. L. & Bourne, N., Sep 1 2005, In : Journal of virology. 79, 17, p. 11537-11540 4 p.

Research output: Contribution to journalArticle

13 Scopus citations
2004

Effect of candidate vaginally-applied microbicide compounds on recognition of antigen by CD4+ and CD8+ T lymphocytes

Milligan, G. N., Chu, C. F., Young, C. G. & Stanberry, L. R., Nov 1 2004, In : Biology of reproduction. 71, 5, p. 1638-1645 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Efficacy of genital T cell responses to herpes simplex virus type 2 resulting from immunization of the nasal mucosa

Milligan, G. N., Dudley-McClain, K. L., Chu, C. F. & Young, C. G., Jan 20 2004, In : Virology. 318, 2, p. 507-515 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

T-cell-mediated mechanisms involved in resolution of genital herpes simplex virus type 2 (HSV-2) infection of mice

Milligan, G. N., Dudley-McClain, K. L., Young, C. G. & Chu, C. F., Apr 1 2004, In : Journal of Reproductive Immunology. 61, 2, p. 115-127 13 p.

Research output: Contribution to journalArticle

27 Scopus citations
2002
32 Scopus citations
2001

Role of polymorphonuclear leukocytes in resolution of HSV-2 infection of the mouse vagina

Milligan, G. N., Bourne, N. & Dudley, K. L., Jan 8 2001, In : Journal of Reproductive Immunology. 49, 1, p. 49-65 17 p.

Research output: Contribution to journalArticle

39 Scopus citations