Photo of Ichiaki Ito

Ichiaki Ito, PhD

  • 724 Citations
  • 14 h-Index
20042020

Research output per year

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Research Output

  • 724 Citations
  • 14 h-Index
  • 24 Article
  • 1 Letter
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Article
2020
2018

Survival of mice with gastrointestinal acute radiation syndrome through control of bacterial translocation

Suzuki, F., Loucas, B., Ito, I., Asai, A., Suzuki, S. & Kobayashi, M., Jul 1 2018, In : Journal of Immunology. 201, 1, p. 77-86 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Lamina propria group 2 innate lymphoid cells impair the antibacterial defense of burned mice to enterococcal translocation

Ito, I., Bhopale, K. K., Kobayashi, M., Finnerty, C., Herndon, D. & Suzuki, F., Dec 1 2017, In : Journal of Leukocyte Biology. 102, 6, p. 1451-1460 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

M2b macrophage polarization accompanied with reduction of long noncoding RNA GAS5

Ito, I., Asai, A., Suzuki, S., Kobayashi, M. & Suzuki, F., 2017, (Accepted/In press) In : Biochemical and Biophysical Research Communications.

Research output: Contribution to journalArticle

12 Scopus citations
2 Scopus citations
2016

Macrophage polarization and MRSA infection in burned mice

Nishiguchi, T., Ito, I., Lee, J., Suzuki, S., Suzuki, F. & Kobayashi, M., Nov 15 2016, (Accepted/In press) In : Immunology and Cell Biology.

Research output: Contribution to journalArticle

6 Scopus citations

The Polarization of M2b Monocytes in Cultures of Burn Patient Peripheral CD14+ Cells Treated with a Selected Human CCL1 Antisense Oligodeoxynucleotide

Ito, I., Bhopale, K. K., Nishiguchi, T., Lee, J., Herndon, D., Suzuki, S., Sowers, L., Suzuki, F. & Kobayashi, M., Oct 1 2016, In : Nucleic Acid Therapeutics. 26, 5, p. 269-276 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

M2b macrophage elimination and improved resistance of mice with chronic alcohol consumption to opportunistic infections

Ohama, H., Asai, A., Ito, I., Suzuki, S., Kobayashi, M., Higuchi, K. & Suzuki, F., Jan 1 2015, In : American Journal of Pathology. 185, 2, p. 420-431 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

M2b monocytes provoke bacterial pneumonia and gut bacteria-associated sepsis in alcoholics

Tsuchimoto, Y., Asai, A., Tsuda, Y., Ito, I., Nishiguchi, T., Garcia, M. C., Suzuki, S., Kobayashi, M., Higuchi, K. & Suzuki, F., Dec 1 2015, In : Journal of Immunology. 195, 11, p. 5169-5177 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype

Nakamura, K., Ito, I., Kobayashi, M., Herndon, D. N. & Suzuki, F., May 1 2015, In : Cytokine. 73, 1, p. 8-15 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2014

Identification of a novel compound that suppresses breast cancer invasiveness by inhibiting transforming growth factor-β signaling via estrogen receptor α

Goto, N., Hiyoshi, H., Ito, I., Iida, K., Nakajima, Y., Nagasawa, K. & Yanagisawa, J., Jan 1 2014, In : Journal of Cancer. 5, 5, p. 336-343 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption

Ono, W., Hayashi, Y., Yokoyama, W., Kuroda, T., Kishimoto, H., Ito, I., Kimura, K., Akaogi, K., Waku, T. & Yanagisawa, J., Feb 21 2014, In : Journal of Biological Chemistry. 289, 8, p. 4928-4940 13 p.

Research output: Contribution to journalArticle

17 Scopus citations
2013

A nonclassical vitamin D receptor pathway suppresses renal fibrosis

Ito, I., Waku, T., Aoki, M., Abe, R., Nagai, Y., Watanabe, T., Nakajima, Y., Ohkido, I., Yokoyama, K., Miyachi, H., Shimizu, T., Murayama, A., Kishimoto, H., Nagasawa, K. & Yanagisawa, J., Nov 1 2013, In : Journal of Clinical Investigation. 123, 11, p. 4579-4594 16 p.

Research output: Contribution to journalArticle

80 Scopus citations

Identification and Characterization of the Direct Interaction between Methotrexate (MTX) and High-Mobility Group Box 1 (HMGB1) Protein

Kuroiwa, Y., Takakusagi, Y., Kusayanagi, T., Kuramochi, K., Imai, T., Hirayama, T., Ito, I., Yoshida, M., Sakaguchi, K. & Sugawara, F., May 3 2013, In : PLoS One. 8, 5, e63073.

Research output: Contribution to journalArticle

24 Scopus citations

Structural basis for vitamin D receptor agonism by novel non-secosteroidal ligands

Asano, L., Ito, I., Kuwabara, N., Waku, T., Yanagisawa, J., Miyachi, H. & Shimizu, T., Apr 2 2013, In : FEBS Letters. 587, 7, p. 957-963 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2011

Estrogen and antiestrogens alter breast cancer invasiveness by modulating the transforming growth factor-β signaling pathway

Goto, N., Hiyoshi, H., Ito, I., Tsuchiya, M., Nakajima, Y. & Yanagisawa, J., Aug 1 2011, In : Cancer Science. 102, 8, p. 1501-1508 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Increased concentration of high-mobility group box 1 protein in milk is related to the severity of bovine mastitis

Furukawa, Y., Hayashi, T., Mizuta, M., Ebara, S., Kiku, Y., Ozawa, T., Matsubara, T., Ito, I., Kitamura, D. & Mizuta, R., Jan 1 2011, In : Veterinary Research Communications. 35, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2010

Estrogen inhibits transforming growth factor β signaling by promoting Smad2/3 degradation

Ito, I., Hanyu, A., Wayama, M., Goto, N., Katsuno, Y., Kawasaki, S., Nakajima, Y., Kajiro, M., Komatsu, Y., Fujimura, A., Hirota, R., Murayama, A., Kimura, K., Imamura, T. & Yanagisawa, J., May 7 2010, In : Journal of Biological Chemistry. 285, 19, p. 14747-14755 9 p.

Research output: Contribution to journalArticle

80 Scopus citations
2009

KLF4 suppresses estrogen-dependent breast cancer growth by inhibiting the transcriptional activity of ERα

Akaogi, K., Nakajima, Y., Ito, I., Kawasaki, S., Oie, S. H., Murayama, A., Kimura, K. & Yanagisawa, J., Aug 13 2009, In : Oncogene. 28, 32, p. 2894-2902 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Lupus antibodies to the HMGB1 chromosomal protein: Epitope mapping and association with disease activity

Hayashi, A., Nagafuchi, H., Ito, I., Hirota, K., Yoshida, M. & Ozaki, S., Feb 13 2009, In : Modern Rheumatology. 19, 3, p. 283-292 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways

Kajiro, M., Hirota, R., Nakajima, Y., Kawanowa, K., So-Ma, K., Ito, I., Yamaguchi, Y., Ohie, S. H., Kobayashi, Y., Seino, Y., Kawano, M., Kawabe, Y. I., Takei, H., Hayashi, S. I., Kurosumi, M., Murayama, A., Kimura, K. & Yanagisawa, J., Feb 9 2009, In : Nature Cell Biology. 11, 3, p. 312-319 8 p.

Research output: Contribution to journalArticle

117 Scopus citations
2008

PPARγ ligands suppress the feedback loop between E2F2 and cyclin-E1

Komatsu, Y., Ito, I., Wayama, M., Fujimura, A., Akaogi, K., Machida, H., Nakajima, Y., Kuroda, T., Ohmori, K., Murayama, A., Kimura, K. & Yanagisawa, J., May 23 2008, In : Biochemical and Biophysical Research Communications. 370, 1, p. 145-148 4 p.

Research output: Contribution to journalArticle

2 Scopus citations
2007

Post-translational methylation of high mobility group box 1 (HMGB1) causes its cytoplasmic localization in neutrophils

Ito, I., Fukazawa, J. & Yoshida, M., Jun 1 2007, In : Journal of Biological Chemistry. 282, 22, p. 16336-16344 9 p.

Research output: Contribution to journalArticle

138 Scopus citations
2004

Conformational difference in HMGB1 proteins of human neutrophils and lymphocytes revealed by epitope mapping of a monoclonal antibody

Ito, I., Mitsuoka, N., Sobajima, J., Uesugi, H., Ozaki, S., Ohya, K. & Yoshida, M., Aug 1 2004, In : Journal of Biochemistry. 136, 2, p. 155-162 8 p.

Research output: Contribution to journalArticle

10 Scopus citations