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Istvan Boldogh, DM&B, PhD

Core Director, Tissue Culture Core Facility

  • 10184 Citations
  • 56 h-Index
1972 …2019
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DNA Glycosylases Medicine & Life Sciences
Cytomegalovirus Medicine & Life Sciences
DNA Repair Medicine & Life Sciences
Reactive Oxygen Species Medicine & Life Sciences
DNA Medicine & Life Sciences
Repair Chemical Compounds
Oxidative Stress Medicine & Life Sciences
Inflammation Medicine & Life Sciences

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Projects 2010 2016

Linkage of Lung Inflammation to 8-Oxoguanine and OGG1

Boldogh, I.

National Inst of Environmental Health Sc

4/15/10 → 1/31/16

Project: Other project

Research Output 1972 2019

C-Abl-mediated tyrosine phosphorylation of PARP1 is crucial for expression of proinflammatory genes

Bohio, A. A., Sattout, A., Wang, R., Wang, K., Sah, R. K., Guo, X., Zeng, X., Ke, Y., Boldogh, I. & Ba, X., Sep 15 2019, In : Journal of Immunology. 203, 6, p. 1521-1531 11 p.

Research output: Contribution to journal › Article

Open Access
Tyrosine
Phosphorylation
Gene Expression
DNA Damage
Poly (ADP-Ribose) Polymerase-1

Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid

Pan, L., Wang, H., Luo, J., Zeng, J., Pi, J., Liu, H., Liu, C., Ba, X., Qu, X., Xiang, Y., Boldogh, I. & Qin, X., Dec 1 2019, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 12, p. 14159-14170 12 p.

Research output: Contribution to journal › Article

DNA Glycosylases
Tissue Inhibitor of Metalloproteinase-1
Epigenomics
RNA
DNA
8 Citations (Scopus)

Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome

Abraham, D., Feher, J., Scuderi, G. L., Szabo, D., Dobolyi, A., Cservenak, M., Juhasz, J., Ligeti, B., Pongor, S., Gomez-Cabrera, M. C., Vina, J., Higuchi, M., Suzuki, K., Boldogh, I. & Radak, Z., Jan 1 2019, In : Experimental Gerontology. 115, p. 122-131 10 p.

Research output: Contribution to journal › Article

Microbiota
Probiotics
Transgenic Mice
Alzheimer Disease
Amyloid
16 Citations (Scopus)

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

Mitra, J., Guerrero, E. N., Hegde, P. M., Liachko, N. F., Wang, H., Vasquez, V., Gao, J., Pandey, A., Paul Taylor, J., Kraemer, B. C., Wu, P., Boldogh, I., Garruto, R. M., Mitra, S., Rao, K. S. & Hegde, M. L., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4696-4705 10 p.

Research output: Contribution to journal › Article

Motor Neuron Disease
Double-Stranded DNA Breaks
DNA Damage
DNA-Binding Proteins
Motor Neurons

Oxidized base 8-oxoguanine, a product of DNA repair processes, contributes to dendritic cell activation

Pázmándi, K., Sütő, M., Fekete, T., Varga, A., Boldizsár, E., Boldogh, I. & Bácsi, A., Nov 1 2019, In : Free Radical Biology and Medicine. 143, p. 209-220 12 p.

Research output: Contribution to journal › Article

Open Access
DNA Glycosylases
DNA Repair
Dendritic Cells
Repair
Chemical activation