Research output per year
Research output per year
- 1 - 50 out of 265 results
Search results
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2023
8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injury
Pan, L., Hao, W., Xue, Y., Wang, K., Zheng, X., Luo, J., Ba, X., Xiang, Y., Qin, X., Bergwik, J., Tanner, L., Egesten, A., Brasier, A. & Boldogh, I., Feb 22 2023, In: Nucleic acids research. 51, 3, p. 1087-1102 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
DNA methylation clock DNAmFitAge shows regular exercise is associated with slower aging and systemic adaptation
Jokai, M., Torma, F., McGreevy, K. M., Koltai, E., Bori, Z., Babszki, G., Bakonyi, P., Gombos, Z., Gyorgy, B., Aczel, D., Toth, L., Osvath, P., Fridvalszky, M., Teglas, T., Posa, A., Kujach, S., Olek, R., Kawamura, T., Seki, Y., Suzuki, K., & 8 others, 2023, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
DNA repair byproduct 8-oxoguanine base promotes myoblast differentiation
Zheng, X., Zhang, W., Hu, Y., Zhao, Z., Wu, J., Zhang, X., Hao, F., Han, J., Xu, J., Hao, W., Wang, R., Tian, M., Radak, Z., Nakabeppu, Y., Boldogh, I. & Ba, X., May 2023, In: Redox Biology. 61, 102634.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Functional analysis of a conserved site mutation in the DNA end processing enzyme PNKP leading to ataxia with oculomotor apraxia type 4 in humans
Islam, A., Chakraborty, A., Gambardella, S., Campopiano, R., Sarker, A. H., Boldogh, I. & Hazra, T., May 2023, In: Journal of Biological Chemistry. 299, 5, 104714.Research output: Contribution to journal › Article › peer-review
Open Access -
No strong association among epigenetic modifications by DNA methylation, telomere length, and physical fitness in biological aging
Seki, Y., Aczel, D., Torma, F., Jokai, M., Boros, A., Suzuki, K., Higuchi, M., Tanisawa, K., Boldogh, I., Horvath, S. & Radak, Z., 2023, (Accepted/In press) In: Biogerontology.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model
Tanner, L., Single, A. B., Bhongir, R. K. V., Heusel, M., Mohanty, T., Karlsson, C. A. Q., Pan, L., Clausson, C. M., Bergwik, J., Wang, K., Andersson, C. K., Oommen, R. M., Erjefält, J. S., Malmström, J., Wallner, O., Boldogh, I., Helleday, T., Kalderén, C. & Egesten, A., Dec 2023, In: Nature communications. 14, 1, 643.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
The Circulating Level of Klotho Is Not Dependent upon Physical Fitness and Age-Associated Methylation Increases at the Promoter Region of the Klotho Gene
Aczel, D., Torma, F., Jokai, M., McGreevy, K., Boros, A., Seki, Y., Boldogh, I., Horvath, S. & Radak, Z., Feb 2023, In: Genes. 14, 2, 525.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2022
Cell-Penetrating Peptide TAT-HuR-HNS3 Suppresses Proinflammatory Gene Expression via Competitively Blocking Interaction of HuR with Its Partners
Wang, K., Tong, H., Gao, Y., Xia, L., Jin, X., Li, X., Zeng, X., Boldogh, I., Ke, Y. & Ba, X., May 15 2022, In: Journal of Immunology. 208, 10, p. 2376-2389 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
CXCL12-CXCR4 在人类恶性肿瘤中的生物学功能
Translated title of the contribution :Biological Functions of CXCL12-CXCR4 in Human Malignant Tumors Research output: Contribution to journal › Review article › peer-review
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Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions
Zheng, X., Wang, K., Pan, L., Hao, W., Xue, Y., Bacsi, A., Vlahopoulos, S. A., Radak, Z., Hazra, T. K., Brasier, A., Tanner, L., Ba, X. & Boldogh, I., Dec 5 2022, In: Journal of Innate Immunity. 14, 6, p. 593-614 22 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Pharmacological OGG1 inhibition decreases murine allergic airway inflammation
Tanner, L., Bergwik, J., Bhongir, R. K. V., Pan, L., Dong, C., Wallner, O., Kalderén, C., Helleday, T., Boldogh, I., Adner, M. & Egesten, A., Oct 17 2022, In: Frontiers in Pharmacology. 13, 999180.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
RELA∙8-Oxoguanine DNA Glycosylase1 Is an Epigenetic Regulatory Complex Coordinating the Hexosamine Biosynthetic Pathway in RSV Infection
Xu, X., Qiao, D., Pan, L., Boldogh, I., Zhao, Y. & Brasier, A. R., Jul 2022, In: Cells. 11, 14, 2210.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The Systemic Effects of Exercise on the Systemic Effects of Alzheimer’s Disease
Aczel, D., Gyorgy, B., Bakonyi, P., Bukhari, R., Pinho, R., Boldogh, I., Yaodong, G. & Radak, Z., May 2022, In: Antioxidants. 11, 5, 1028.Research output: Contribution to journal › Review article › peer-review
Open Access7 Scopus citations -
2021
Endothelial dysfunction through oxidatively generated epigenetic mark in respiratory viral infections
Vlahopoulos, S., Wang, K., Xue, Y., Zheng, X., Boldogh, I. & Pan, L., Nov 2021, In: Cells. 10, 11, 3067.Research output: Contribution to journal › Review article › peer-review
Open Access4 Scopus citations -
Intrapulmonary administration of purified NEIL2 abrogates NF-κB-mediated inflammation
Tapryal, N., Shahabi, S., Chakraborty, A., Hosoki, K., Wakamiya, M., Sarkar, G., Sharma, G., Cardenas, V. J., Boldogh, I., Sur, S., Ghosh, G. & Hazra, T. K., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100723.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization
Ke, Y., Lv, X., Fu, X., Zhang, J., Bohio, A. A., Zeng, X., Hao, W., Wang, R., Boldogh, I. & Ba, X., Feb 2021, In: Cellular and Molecular Life Sciences. 78, 4, p. 1817-1835 19 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
2020
Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription
Hao, W., Wang, J., Zhang, Y., Wang, C., Xia, L., Zhang, W., Zafar, M., Kang, J. Y., Wang, R., Ali Bohio, A., Pan, L., Zeng, X., Wei, M., Boldogh, I. & Ba, X., Jun 1 2020, In: FASEB Journal. 34, 6, p. 7427-7441 15 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Exercise, redox system and neurodegenerative diseases
Quan, H., Koltai, E., Suzuki, K., Aguiar, A. S., Pinho, R., Boldogh, I., Berkes, I. & Radak, Z., Oct 1 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 10, 165778.Research output: Contribution to journal › Review article › peer-review
Open Access34 Scopus citations -
Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle
Dharmalingam, P., Talakatta, G., Mitra, J., Wang, H., Derry, P. J., Nilewski, L. G., McHugh, E. A., Fabian, R. H., Mendoza, K., Vasquez, V., Hegde, P. M., Kakadiaris, E., Roy, T., Boldogh, I., Hegde, V. L., Mitra, S., Tour, J. M., Kent, T. A. & Hegde, M. L., Mar 24 2020, In: ACS Nano. 14, 3, p. 2827-2846 20 p.Research output: Contribution to journal › Article › peer-review
37 Scopus citations -
The COVID-19 pandemic and physical activity
Woods, J. A., Hutchinson, N. T., Powers, S. K., Roberts, W. O., Gomez-Cabrera, M. C., Radak, Z., Berkes, I., Boros, A., Boldogh, I., Leeuwenburgh, C., Coelho-Júnior, H. J., Marzetti, E., Cheng, Y., Liu, J., Durstine, J. L., Sun, J. & Ji, L. L., Jun 2020, In: Sports Medicine and Health Science. 2, 2, p. 55-64 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access304 Scopus citations -
The systemic role of SIRT1 in exercise mediated adaptation
Radak, Z., Suzuki, K., Posa, A., Petrovszky, Z., Koltai, E. & Boldogh, I., Aug 2020, In: Redox Biology. 35, 101467.Research output: Contribution to journal › Review article › peer-review
Open Access47 Scopus citations -
2019
C-Abl-mediated tyrosine phosphorylation of PARP1 is crucial for expression of proinflammatory genes
Bohio, A. A., Sattout, A., Wang, R., Wang, K., Sah, R. K., Guo, X., Zeng, X., Ke, Y., Boldogh, I. & Ba, X., Sep 15 2019, In: Journal of Immunology. 203, 6, p. 1521-1531 11 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Epigenetic regulation of TIMP1 expression by 8-oxoguanine DNA glycosylase-1 binding to DNA:RNA hybrid
Pan, L., Wang, H., Luo, J., Zeng, J., Pi, J., Liu, H., Liu, C., Ba, X., Qu, X., Xiang, Y., Boldogh, I. & Qin, X., Dec 1 2019, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 12, p. 14159-14170 12 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Exercise and probiotics attenuate the development of Alzheimer's disease in transgenic mice: Role of microbiome
Abraham, D., Feher, J., Scuderi, G. L., Szabo, D., Dobolyi, A., Cservenak, M., Juhasz, J., Ligeti, B., Pongor, S., Gomez-Cabrera, M. C., Vina, J., Higuchi, M., Suzuki, K., Boldogh, I. & Radak, Z., Jan 2019, In: Experimental Gerontology. 115, p. 122-131 10 p.Research output: Contribution to journal › Article › peer-review
155 Scopus citations -
Exercise effects on physiological function during aging
Radak, Z., Torma, F., Berkes, I., Goto, S., Mimura, T., Posa, A., Balogh, L., Boldogh, I., Suzuki, K., Higuchi, M. & Koltai, E., Feb 20 2019, In: Free Radical Biology and Medicine. 132, p. 33-41 9 p.Research output: Contribution to journal › Review article › peer-review
57 Scopus citations -
Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects
Mitra, J., Guerrero, E. N., Hegde, P. M., Liachko, N. F., Wang, H., Vasquez, V., Gao, J., Pandey, A., Paul Taylor, J., Kraemer, B. C., Wu, P., Boldogh, I., Garruto, R. M., Mitra, S., Rao, K. S. & Hegde, M. L., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4696-4705 10 p.Research output: Contribution to journal › Article › peer-review
Open Access160 Scopus citations -
Oxidized base 8-oxoguanine, a product of DNA repair processes, contributes to dendritic cell activation
Pázmándi, K., Sütő, M., Fekete, T., Varga, A., Boldizsár, E., Boldogh, I. & Bácsi, A., Nov 1 2019, In: Free Radical Biology and Medicine. 143, p. 209-220 12 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer
Vlahopoulos, S., Adamaki, M., Khoury, N., Zoumpourlis, V. & Boldogh, I., Feb 2019, In: Pharmacology and Therapeutics. 194, p. 59-72 14 p.Research output: Contribution to journal › Review article › peer-review
39 Scopus citations -
Targeting inducible epigenetic reprogramming pathways in chronic airway remodeling
Brasier, A. & Boldogh, I., 2019, In: Drugs in Context. 8, 2019-8-3.Research output: Contribution to journal › Review article › peer-review
Open Access8 Scopus citations -
2018
8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions
Ba, X. & Boldogh, L., Apr 2018, In: Redox Biology. 14, p. 669-678 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access160 Scopus citations -
Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA
Hao, W., Qi, T., Pan, L., Wang, R., Zhu, B., Aguilera-Aguirre, L., Radak, Z., Hazra, T. K., Vlahopoulos, S. A., Bacsi, A., Brasier, A., Ba, X. & Boldogh, I., Sep 2018, In: Redox Biology. 18, p. 43-53 11 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation
Hosoki, K., Jaruga, P., Itazawa, T., Aguilera-Aguirre, L., Coskun, E., Hazra, T. K., Boldogh, I., Dizdaroglu, M. & Sur, S., Dec 2018, In: Clinical and Experimental Allergy. 48, 12, p. 1676-1687 12 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls
Koltai, E., Bori, Z., Osvath, P., Ihasz, F., Peter, S., Toth, G., Degens, H., Rittweger, J., Boldogh, I. & Radak, Z., Oct 2018, In: Redox Biology. 19, p. 46-51 6 p.Research output: Contribution to journal › Article › peer-review
Open Access40 Scopus citations -
OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos
Wang, R., Li, C., Qiao, P., Xue, Y., Zheng, X., Chen, H., Zeng, X., Liu, W., Boldogh, I. & Ba, X., Jun 1 2018, In: Cell Death and Disease. 9, 6, 628.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation
Visnes, T., Cázares-Körner, A., Hao, W., Wallner, O., Masuyer, G., Loseva, O., Mortusewicz, O., Wiita, E., Sarno, A., Manoilov, A., Astorga-Wells, J., Jemth, A. S., Pan, L., Sanjiv, K., Karsten, S., Gokturk, C., Grube, M., Homan, E. J., Hanna, B. M. F., Paulin, C. B. J., & 20 others, Nov 16 2018, In: Science. 362, 6416, p. 834-839 6 p.Research output: Contribution to journal › Article › peer-review
120 Scopus citations -
The establishment of methods for free PAR generation and PAR reader detection
Ke, Y., Wang, K., Xu, H., Wang, C., Zhang, J., Zeng, X., Wang, R., Boldogh, I. & Ba, X., Jun 2018, In: Molecular and Cellular Probes. 39, p. 57-60 4 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
The roles of base excision repair enzyme OGG1 in gene expression
Wang, R., Hao, W., Pan, L., Boldogh, I. & Ba, X., Oct 1 2018, In: Cellular and Molecular Life Sciences. 75, 20, p. 3741-3750 10 p.Research output: Contribution to journal › Review article › peer-review
56 Scopus citations -
2017
8-Oxoguanine DNA glycosylase1–driven DNA repair—A paradoxical role in lung aging
German, P., Saenz, D., Szaniszlo, P., Aguilera-Aguirre, L., Pan, L., Hegde, M. L., Bacsi, A., Hajas, G., Radak, Z., Ba, X., Mitra, S., Papaconstantinou, J. & Boldogh, I., Jan 1 2017, In: Mechanisms of Ageing and Development. 161, p. 51-65 15 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?
Wang, H., Dharmalingam, P., Vasquez, V., Mitra, J., Boldogh, I., Rao, K. S., Kent, T. A., Mitra, S. & Hegde, M. L., Jan 1 2017, In: Mechanisms of Ageing and Development. 161, p. 163-176 14 p.Research output: Contribution to journal › Review article › peer-review
23 Scopus citations -
Erratum: PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR
Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 31 2017, In: Nature communications. 8, p. 15191 1 p., 15191.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve
Radak, Z., Ishihara, K., Tekus, E., Varga, C., Posa, A., Balogh, L., Boldogh, I. & Koltai, E., Aug 1 2017, In: Redox Biology. 12, p. 285-290 6 p.Research output: Contribution to journal › Short survey › peer-review
Open Access114 Scopus citations -
Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats
Pajk, M., Cselko, A., Varga, C., Posa, A., Tokodi, M., Boldogh, I., Goto, S. & Radak, Z., Aug 1 2017, In: Biogerontology. 18, 4, p. 593-600 8 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Innate mechanism of pollen- and cat dander–induced oxidative stress and DNA damage in the airways
Hosoki, K., Redding, D., Itazawa, T., Chakraborty, A., Tapryal, N., Qian, S., Qi, H., Aguilera-Aguirre, L., Brasier, A., Phani, V. S., Hazra, T. K., Boldogh, I. & Sur, S., Nov 2017, In: Journal of Allergy and Clinical Immunology. 140, 5, p. 1436-1439.e5Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
NF-κB mediates mesenchymal transition, remodeling, and pulmonary fibrosis in response to chronic inflammation by viral RNA patterns
Tian, B., Patrikeev, I., Ochoa, L., Vargas, G., Belanger, K. A. K., Litvinov, J., Boldogh, I., Ameredes, B. T., Motamedi, M. & Brasier, A. R., Apr 2017, In: American journal of respiratory cell and molecular biology. 56, 4, p. 506-520 15 p.Research output: Contribution to journal › Article › peer-review
50 Scopus citations -
OGG1-DNA interactions facilitate NF-k B binding to DNA targets
Pan, L., Hao, W., Zheng, X., Zeng, X., Ahmed Abbasi, A., Boldogh, I. & Ba, X., Mar 7 2017, In: Scientific reports. 7, 43297.Research output: Contribution to journal › Article › peer-review
Open Access48 Scopus citations -
PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR
Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 8 2017, In: Nature communications. 8, 14632.Research output: Contribution to journal › Article › peer-review
Open Access50 Scopus citations -
Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation
Aguilera-Aguirre, L., Hao, W., Pan, L., Li, X., Saavedra-Molina, A., Bacsi, A., Radak, Z., Sur, S., Brasier, A., Ba, X. & Boldogh, I., Dec 2017, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 313, 6, p. L1058-L1068Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Regulation of type I interferon responses by mitochondria-derived reactive oxygen species in plasmacytoid dendritic cells
Agod, Z., Fekete, T., Budai, M. M., Varga, A., Szabo, A., Moon, H., Boldogh, I., Biro, T., Lanyi, A., Bacsi, A. & Pazmandi, K., Oct 2017, In: Redox Biology. 13, p. 633-645 13 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Scopus citations -
Reply: Protease plays a role in ragweed pollen-induced neutrophil recruitment and epithelial barrier disruption
Hosoki, K., Brasier, A., Kurosky, A., Boldogh, I. & Sur, S., Feb 2017, In: American journal of respiratory cell and molecular biology. 56, 2, p. 272-273 2 p.Research output: Contribution to journal › Letter › peer-review
3 Scopus citations -
SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle
Koltai, E., Bori, Z., Chabert, C., Dubouchaud, H., Naito, H., Machida, S., Davies, K. J. A., Murlasits, Z., Fry, A. C., Boldogh, I. & Radak, Z., Jun 1 2017, In: Journal of Physiology. 595, 11, p. 3361-3376 16 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations