• 2773 Citations
  • 30 h-Index
1992 …2020
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Personal profile

Personal profile

1999 - present

Institute for Human Infections & Immunity

1999 - present

Center for Tropical Diseases

2002 - present

Experimental Pathology Graduate Faculty

2002 - present

Center for Biodefense and Emerging Infectious Disease

2002 - present

Sealy Center for Vaccine Development

Research Interests

  • Role of post translational modifications on host-pathogen interactions and subcellular localization
  • Nucleomodulins, modulation of host transcription and epigenetic signature by intracellular bacteria
  • Molecular pathobiology of obligately intracellular bacteria and immune evasion
  • Effector proteins and secretion mechanisms (type 1) of obligately intracellular bacteria
  • Molecular mechanisms involved in adaptation to mammalian and arthropod hosts by Ehrlichia
  • Molecular and immunodiagnostics for medically important Ehrlichia species
  • Subunit vaccine development for the ehrlichioses

 

Professional Information

2011-present Director, Experimental Pathology Graduate Program
2012-present Member, Human Pathophysiology and Translation Medicine Graduate Faculty
2012-presentProfessor, Departments of Pathology and Microbiology & Immunology, University of Texas Medical Branch, Galveston, Texas
2015-presentMember, Cell Biology Graduate Faculty

Teaching

School of Medicine

2005-presentPathobiology & Host Defenses (PHD) Course Committee Member; Immunology Subcommittee
2005-presentLaboratory Research in Microbial Pathogenesis Selective (PATU 4051)
2003-11Pathobiology & Host Defenses (PHD) Course; Problem Based Learning Facilitator (48 hrs)
2007-11Pathobiology & Host Defenses (PHD) Laboratory Instructor (10-15 hrs)
2003-06Cardiovascular & Pulmonary (CVP) Clinical Microbiology Laboratory Instructor (12 hrs)

Graduate School of Biomedical Sciences

Administration

2011-presentDirector, Experimental Pathology Graduate Program (elected)
2010-2011Associate Director, Experimental Pathology Graduate Program (appointed)

Teaching

2011-presentVaccine Development Pathway: From Discovery to Licensure (BBSC 6219; 1 lecture)
2009-presentIntroduction to Vaccinology: Vaccines for the 21st Century (PATH 6161; 1 lecture)
2007-presentPathogenic Bacteriology (MICR 6315; 1 lecture)
2006-presentMolecular Biology and Genetics (BBSC 6403; l lecture)
2003-2011Introduction to Competitive Grant Writing (PATX 6279; Director; 20 hrs)
2004Pathogenesis of Infectious Disease (PATX 6360; 1 lecture)
2003Experimental Design and Analysis (PATX-6000-054; Co-director; 16 hrs)

Education/Academic qualification

Comparative Pathology, University of California Davis

… → 1997

Microbiology/Immunology, Louisiana State University

… → 1993

Microbiology, Louisiana State University

… → 1987

Keywords

  • Vaccine Development
  • Host-pathogen Interactions

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2007 2020

Research Output 1992 2018

  • 2773 Citations
  • 30 h-Index
  • 87 Article
  • 9 Chapter
  • 3 Conference contribution
  • 2 Review article

Ehrlichia chaffeensis TRP120 effector targets and recruits host polycomb group proteins for degradation to promote intracellular infection

Mitra, S., Dunphy, P. S., Das, S., Zhu, B., Luo, T. & McBride, J., Apr 1 2018, In : Infection and Immunity. 86, 4, e00845-17.

Research output: Contribution to journalArticle

Ehrlichia chaffeensis
Polycomb-Group Proteins
Polycomb Repressive Complex 1
Proteolysis
Protein Isoforms
1 Citation (Scopus)

Ehrlichia chaffeensis TRP120 nucleomodulin binds DNA with disordered tandem repeat domain

Klema, V. J., Sepuru, K. M., Füllbrunn, N., Farris, T. R., Dunphy, P. S., McBride, J., Rajarathnam, K. & Choi, K., Apr 1 2018, In : PLoS One. 13, 4, e0194891.

Research output: Contribution to journalArticle

Ehrlichia chaffeensis
Tandem Repeat Sequences
tandem repeat sequences
DNA
Proteins

Ehrlichia chaffeensis TRP32 nucleomodulin function and localization is regulated by NEDD4L-mediated ubiquitination

Farris, T. R., Zhu, B., Wang, J. Y. & McBride, J., Jan 11 2018, In : Frontiers in cellular and infection microbiology. 7, JAN, 534.

Research output: Contribution to journalArticle

Ehrlichia chaffeensis
Ubiquitination
Lysine
Ubiquitin-Protein Ligases
Proteasome Endopeptidase Complex
Ehrlichia chaffeensis
Signal transduction
signal transduction
Signal Transduction
Genes
Open Access
Ehrlichia chaffeensis
Cytoskeleton
Homeostasis
Apoptosis
Infection

Activities 2013 2014

  • 3 Types of External academic engagement - Membership of peer review panel or committee

National Institutes of Health Special Emphasis Panel ZRG-1 IMD-B

Jere McBride (Reviewer)
2014

Activity: Other activity typesTypes of External academic engagement - Membership of peer review panel or committee

Czech Science Foundation

Jere McBride (Member)
2013

Activity: Other activity typesTypes of External academic engagement - Membership of peer review panel or committee

National Institutes of Health Special Emphasis Panel ZRG1 VH-D

Jere McBride (Member)
2013

Activity: Other activity typesTypes of External academic engagement - Membership of peer review panel or committee