Jere McBride, PhD, MS

Program Director, Experimental Pathology

  • 3066 Citations
  • 33 h-Index
1992 …2022

Research output per year

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Research Output

2020

Ehrlichia canis TRP36 diversity in naturally infected-dogs from an urban area of Colombia

Arroyave, E., Rodas-González, J. D., Zhang, X., Labruna, M. B., González, M. S., Fernández-Silva, J. A. & McBride, J. W., May 2020, In : Ticks and Tick-borne Diseases. 11, 3, 101367.

Research output: Contribution to journalArticle

Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection

Wang, J. Y., Zhu, B., Patterson, L. N. L., Rogan, M. R., Kibler, C. E. & McBride, J. W., Apr 1 2020, In : PLoS pathogens. 16, 4, e1008541.

Research output: Contribution to journalArticle

Open Access
2019

Bacterial manipulation of wnt signaling: A host-pathogen tug-of-wnt

Rogan, M. R., Patterson, L. L., Wang, J. Y. & McBride, J. W., Jan 1 2019, In : Frontiers in immunology. 10, OCT, 2390.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
Open Access
2018

Ehrlichia chaffeensis TRP120 effector targets and recruits host polycomb group proteins for degradation to promote intracellular infection

Mitra, S., Dunphy, P. S., Das, S., Zhu, B., Luo, T. & McBride, J., Apr 1 2018, In : Infection and Immunity. 86, 4, e00845-17.

Research output: Contribution to journalArticle

3 Scopus citations

Ehrlichia chaffeensis TRP120 nucleomodulin binds DNA with disordered tandem repeat domain

Klema, V. J., Sepuru, K. M., Füllbrunn, N., Farris, T. R., Dunphy, P. S., McBride, J., Rajarathnam, K. & Choi, K., Apr 1 2018, In : PLoS One. 13, 4, e0194891.

Research output: Contribution to journalArticle

3 Scopus citations

Ehrlichia chaffeensis TRP32 nucleomodulin function and localization is regulated by NEDD4L-mediated ubiquitination

Farris, T. R., Zhu, B., Wang, J. Y. & McBride, J., Jan 11 2018, In : Frontiers in cellular and infection microbiology. 7, JAN, 534.

Research output: Contribution to journalArticle

3 Scopus citations
3 Scopus citations
Open Access
1 Scopus citations
2017

Ehrlichia chaffeensis tandem repeat effector targets differentially influence infection

Luo, T., Dunphy, P. S. & McBride, J., May 12 2017, In : Frontiers in cellular and infection microbiology. 7, MAY, 178.

Research output: Contribution to journalArticle

4 Scopus citations
6 Scopus citations

Engineering of obligate intracellular bacteria: Progress, challenges and paradigms

McClure, E. E., Chávez, A. S. O., Shaw, D. K., Carlyon, J. A., Ganta, R. R., Noh, S. M., Wood, D. O., Bavoil, P. M., Brayton, K. A., Martinez, J. J., McBride, J. W., Valdivia, R. H., Munderloh, U. G. & Pedra, J. H. F., Sep 1 2017, In : Nature Reviews Microbiology. 15, 9, p. 544-558 15 p.

Research output: Contribution to journalReview article

34 Scopus citations

Tick-Borne Emerging Infections. Ehrlichiosis and Anaplasmosis

Ismail, N. & McBride, J., 2017, (Accepted/In press) In : Clinics in Laboratory Medicine.

Research output: Contribution to journalArticle

38 Scopus citations
2016

Detection of genotype-specific Ehrlichia canis exposure in Brazilian dogs by TRP36 peptide ELISA

Aguiar, D. M., Zhang, X., Braga, I. A., Taques, I. I. G. G. & McBride, J., Feb 1 2016, In : Ticks and Tick-borne Diseases. 7, 1, p. 142-145 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ehrlichia chaffeensis exploits canonical and noncanonical host Wnt signaling pathways to stimulate phagocytosis and promote intracellular survival

Luo, T., Dunphy, P. S., Lina, T. T. & McBride, J., Mar 1 2016, In : Infection and Immunity. 84, 3, p. 686-700 15 p.

Research output: Contribution to journalArticle

24 Scopus citations

Ehrlichia chaffeensis TRP120 activates canonical notch signaling to downregulate TLR2/4 expression and promote intracellular survival

Lina, T. T., Dunphy, P. S., Luo, T. & McBride, J., Jul 1 2016, In : mBio. 7, 4, e00672-16.

Research output: Contribution to journalArticle

18 Scopus citations

Ehrlichia chaffeensis TRP32 is a nucleomodulin that directly regulates expression of host genes governing differentiation and proliferation

Farris, T. R., Dunphy, P. S., Zhu, B., Kibler, C. E. & McBride, J., 2016, In : Infection and Immunity. 84, 11, p. 3182-3194 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Hacker within! Ehrlichia chaffeensis effector driven phagocyte reprogramming strategy

Lina, T. T., Farris, T., Luo, T., Mitra, S., Zhu, B. & McBride, J., May 31 2016, In : Frontiers in cellular and infection microbiology. 6, MAY, 58.

Research output: Contribution to journalReview article

11 Scopus citations

Rapid identification of ubiquitination and SUMOylation target sites by microfluidic peptide array

Zhu, B., Farris, T. R., Milligan, S. L., Chen, H., Zhu, R., Hong, A., Zhou, X., Gao, X. & McBride, J., Mar 1 2016, In : Biochemistry and Biophysics Reports. 5, p. 430-438 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation

Wang, X., Shaw, D. K., Hammond, H. L., Sutterwala, F. S., Rayamajhi, M., Shirey, K. A., Perkins, D. J., Bonventre, J. V., Velayutham, T. S., Evans, S. M., Rodino, K. G., VieBrock, L., Scanlon, K. M., Carbonetti, N. H., Carlyon, J. A., Miao, E. A., McBride, J. W., Kotsyfakis, M. & Pedra, J. H. F., Aug 2016, In : PLoS pathogens. 12, 8, e1005803.

Research output: Contribution to journalArticle

13 Scopus citations
2015

A West Nile virus NS4B-P38G mutant strain induces cell intrinsic innate cytokine responses in human monocytic and macrophage cells

Xie, G., Luo, H., Tian, B., Mann, B., Bao, X., McBride, J., Tesh, R., Barrett, A. D. & Wang, T., Feb 11 2015, In : Vaccine. 33, 7, p. 869-878 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Advances in vaccines, diagnostics and pathobiology

McBride, J. W., 2014, Ehrlichia.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

A novel Ehrlichia genotype strain distinguished by the TRP36 gene naturally infects cattle in Brazil and causes clinical manifestations associated with ehrlichiosis

Aguiar, D. M., Ziliani, T. F., Zhang, X., Melo, A. L. T., Braga, Í. A., Witter, R., Freitas, L. C., Rondelli, A. L. H., Luis, M. A., Sorte, E. C. B., Jaune, F. W., Santarém, V. A., Horta, M. C., Pescador, C. A., Colodel, E. M., Soares, H. S., Pacheco, R. C., Onuma, S. S. M., Labruna, M. B. & McBride, J. W., Sep 2014, In : Ticks and Tick-borne Diseases. 5, 5, p. 537-544 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Ehrlichia chaffeensis exploits Host SUMOylation pathways to mediate effector-host interactions and promote intracellular survival

Dunphy, P. S., Luo, T. & McBride, J. W., Jan 1 2014, In : Infection and immunity. 82, 10, p. 4154-4168 15 p.

Research output: Contribution to journalArticle

33 Scopus citations

Pathogenesis of Infectious Diseases and Mechanisms of Immunity

McBride, J. & Walker, D., Dec 9 2014, Vaccinology: An Essential Guide. Wiley Blackwell, p. 59-72 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Ehrlichia moonlighting effectors and interkingdom interactions with the mononuclear phagocyte

Dunphy, P. S., Luo, T. & McBride, J. W., Dec 1 2013, In : Microbes and Infection. 15, 14-15, p. 1005-1016 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Genetic diversity of Ehrlichia canis in Brazil

Aguiar, D. M., Zhang, X., Melo, A. L. T., Pacheco, T. A., Meneses, A. M. C., Zanutto, M. S., Horta, M. C., Santarém, V. A., Camargo, L. M. A., McBride, J. W. & Labruna, M. B., Mar 13 2013, In : Veterinary Microbiology. 164, 3-4, p. 315-321 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In : Vaccine. 31, 50, p. 5960-5967 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2012

Ehrlichia chaffeensis TRP32 interacts with host cell targets that influence intracellular survival

Luo, T. & McBride, J. W., Jul 1 2012, In : Infection and immunity. 80, 7, p. 2297-2306 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Human ehrlichioses and rickettsioses in Cameroon

Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

Research output: Chapter in Book/Report/Conference proceedingChapter

Molecular basis of antibody mediated immunity against Ehrlichia chaffeensis involves species-specific linear epitopes in tandem repeat proteins

Kuriakose, J. A., Zhang, X., Luo, T. & McBride, J. W., Oct 1 2012, In : Microbes and Infection. 14, 12, p. 1054-1063 10 p.

Research output: Contribution to journalArticle

18 Scopus citations
2011
33 Scopus citations

Ehrlichia chaffeensis transcriptome in mammalian and arthropod hosts reveals differential gene expression and post transcriptional regulation

Kuriakose, J. A., Miyashiro, S., Luo, T., Zhu, B. & McBride, J. W., Sep 12 2011, In : PloS one. 6, 9, e24136.

Research output: Contribution to journalArticle

34 Scopus citations

Ehrlichia chaffeensis TRP120 binds a G+C-rich motif in host cell DNA and exhibits eukaryotic transcriptional activator function

Zhu, B., Kuriakose, J. A., Luo, T., Ballesteros, E., Gupta, S., Fofanov, Y. & McBride, J. W., Nov 1 2011, In : Infection and immunity. 79, 11, p. 4370-4381 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Ehrlichia chaffeensis TRP120 interacts with a diverse array of eukaryotic proteins involved in transcription, signaling, and cytoskeleton organization

Luo, T., Kuriakose, J. A., Zhu, B., Wakeel, A. & McBride, J. W., Nov 1 2011, In : Infection and immunity. 79, 11, p. 4382-4391 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Eukaryote interactions and tandem and ankyrin repeat effectors

McBride, J. W., Wakeel, A. & Kuriakose, J. A., 2011, Ehrlichia.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

35 Scopus citations

Tyrosine-phosphorylated Ehrlichia chaffeensis and Ehrlichia canis tandem repeat orthologs contain a major continuous cross-reactive antibody epitope in lysine-rich repeats

McBride, J. W., Zhang, X., Wakeel, A. & Kuriakose, J. A., Aug 1 2011, In : Infection and immunity. 79, 8, p. 3178-3187 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010

Ehrlichia

McBride, J. W., 2010, Molecular Detection of Human Bacterial Pathogens. Taylor & Francis CRC Press, p. 647-657

Research output: Chapter in Book/Report/Conference proceedingChapter

Human ehrlichiosis and anaplasmosis

Ismail, N., Bloch, K. C. & McBride, J. W., Mar 1 2010, In : Clinics in Laboratory Medicine. 30, 1, p. 261-292 32 p.

Research output: Contribution to journalReview article

148 Scopus citations
15 Scopus citations
23 Scopus citations

New insights into molecular Ehrlichia chaffeensis-host interactions

Wakeel, A., Zhu, B., Yu, X. J. & McBride, J. W., May 1 2010, In : Microbes and Infection. 12, 5, p. 337-345 9 p.

Research output: Contribution to journalShort survey

22 Scopus citations

Predominance of Ehrlichia chaffeensis in Rhipicephalus sanguineus ticks from kennel-confined dogs in Limbe, Cameroon

Ndip, L. M., Ndip, R. N., Esemu, S. N., Walker, D. H. & McBride, J. W., Jan 1 2010, In : Experimental and Applied Acarology. 50, 2, p. 163-168 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Progress and obstacles in vaccine development for the ehrlichioses

McBride, J. W. & Walker, D. H., Sep 1 2010, In : Expert review of vaccines. 9, 9, p. 1071-1082 12 p.

Research output: Contribution to journalReview article

13 Scopus citations
2009
51 Scopus citations

Ehrlichia

McBride, J. W., Dec 1 2009, Vaccines for Biodefense and Emerging and Neglected Diseases. Elsevier Inc., p. 919-937 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Ehrlichia

McBride, J. W. & Allsop, BA., 2009, Genome Mapping and Genomics in Animal-Associated Microbes. Springer-Verlag Berlin Heidelberg, p. 117-165

Research output: Chapter in Book/Report/Conference proceedingChapter

30 Scopus citations