• 3487 Citations
  • 32 h-Index
1994 …2023

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1994

Synthesis and properties of novel amino acid linked phosphoryl nitrogen mustard derivatives

Chen, RY. Y., Wang, HL. L. & Zhou, J., 1994, In : Heteroatom Chemistry. 5, 5-6, p. 497-501 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Synthesis and properties of novel nitrogen mustard linked phosphoryl diamide derivatives

Chen, R. Y., Mao, L. J., Wang, H. L. & Zhou, J., Apr 1 1994, In : Phosphorus, Sulfur, and Silicon and the Related Elements. 89, 1-4, p. 89-95 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
1995

Synthesis of 3, 4-diphenyl-l, 3, 4- diazaphospholidin-2-thione-4-oxides and their quantitative structure-herbicidal activity relationship

Wang, H. L., Zhou, J., Qiu, Y. G., Feng, K. S. & Chen, R. Y., Jul 1 1995, In : Phosphorus, Sulfur, and Silicon and the Related Elements. 104, 1-4, p. 135-141 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
1996

A simple, efficient procedure for the synthesis of some amino acid linked ureido phosphoramidate derivatives

Chen, R. Y. & Zhou, J., Dec 1 1996, In : Chinese Chemical Letters. 7, 6, p. 539-542 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Synthesis and properties of novel α-phosphoryl(thio)ureido alkanephosphonate derivatives

Zhou, J. & Chen, R. Y., Jan 1 1996, In : Phosphorus, Sulfur and Silicon and Related Elements. 118, 1-4, p. 247-256 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
1997

Progress in the Asymmetric Synthesis of Phospholipids

Chen, R. Y. & Zhou, J., Dec 1 1997, In : Chinese Journal of Organic Chemistry. 17, 3, p. 201-202 2 p.

Research output: Contribution to journalArticle

15 Scopus citations

Studies on organophosphorus heterocycles part XI, a new route to cyclic phospholipid analogues via cyclization of lawesson's reagent with long-chain 1-glyceryl ethers

He, L. N., Zhuo, R. X., Chen, R. Y. & Zhou, J., Jan 1 1997, In : Synthetic Communications. 27, 16, p. 2853-2856 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Synthesis and Crystal Structure of 1-(o-methylphenyl)-2- (p-methoxyphenyl)-1,3,2-diazaphospholidin-4-thione-2-sulfide

He, L. N., Chen, R. Y., Zhou, J., Hong-Gen, W. & Xin-Kan, Y., Dec 1 1997, In : Jiegou Huaxue. 16, 3, p. 215-218 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Synthesis and crystal structure of α-(3-phenylureido)-α-(2,4-dichloroptienyl) methyl phenylphosphinic acid

Zhou, J., Chen, R. Y., Wang, H. G. & Yao, X. K., Dec 1 1997, In : Jiegou Huaxue. 16, 3, p. 207-210 4 p.

Research output: Contribution to journalArticle

Synthesis and stereochemistry of new cyclic phosphate-phosphonates

Zhou, J. & Chen, R. Y., Dec 1 1997, In : Chinese Chemical Letters. 8, 1, p. 11-12 2 p.

Research output: Contribution to journalArticle

1 Scopus citations
1998

A convenient and efficient synthesis of novel cyclic phospholipid analogues containing thio(seleno) phosphate-phosphonate linkages

Zhou, J. & Chen, R. Y., Jan 1 1998, In : Synthetic Communications. 28, 14, p. 2653-2657 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

A facile synthesis of new 2-phosphonobenzyloxy-1, 3, 2-benzoxaza(dioxa or diaza)phospholes

Zhou, J. & Chen, R., Dec 1998, In : Organic Preparations and Procedures International. 30, 6, p. 716-719 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
1 Scopus citations

Efficient and Highly Regioselective Formation of the C=N Double Bond via Phosphoryl Thiourea Compounds

Zhou, J. & Chen, R. Y., Jan 1 1998, In : Journal of Chemical Research - Part S. 5, p. 254-255 2 p.

Research output: Contribution to journalArticle

4 Scopus citations
18 Scopus citations

Synthesis of 2-(p-toluenesulfonamido)-4-phenyl-4,5-dihydro-1H-1,3,4- diazaphosphole 4-oxides

Zhou, J., Qiu, Y., Feng, K. & Chen, R. Y., Jan 1 1998, In : Synthetic Communications. 28, 24, p. 4673-4678 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Synthesis of novel thio(seleno) phosphate-phosphonates and their biological activities

Zhou, J., Chen, R. & Yang, X., Jan 1 1998, In : Heteroatom Chemistry. 9, 4, p. 369-375 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
1999

Crystal Structure of 2-[(P,P-Diphenoxy)phosphono(p-methyl)benzyl]-1, 2-benzisoselenazol-3(2H)-one

Zhou, J., Huang, J. M., Tang, Y. & Chen, R. Y., Dec 1 1999, In : Jiegou Huaxue. 18, 2, p. 103-106 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Crystal Structure of cis-2-[(P, P-Diethoxy) phosphono(m-nitro)benzyloxy]-4-phenyl-5,5-dimethyl-1,3,2-dioxaphosphorinane 2-sulfide

Zhou, J., Chen, R. Y. & Wang, H. G., Dec 1 1999, In : Jiegou Huaxue. 18, 2, p. 98-102 5 p.

Research output: Contribution to journalArticle

Facile and stereospecific synthesis of cis-3-(N'-arylureido)-2,3- dihydro-2-phenyl-1,2-benzoxaphosphole 2-oxides

Zhou, J., Qiu, Y., Feng, K. & Chen, R., Jan 1 1999, In : Synthesis. 2, p. 234-236 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Studies on cyclic α-aminoalkanephosphonate compounds: A novel synthesis of 2-phenyl-1,4,2-benzoxaza (or diaza)phosphorin 2-oxides

Zhou, J., Qiu, Y., Feng, K. & Chen, R., Jan 1 1999, In : Synthesis. 1, p. 40-42 3 p.

Research output: Contribution to journalArticle

24 Scopus citations

Synthesis and crystal structure of 2-phosphonoalkyl-1, 2-benzisoselenazol-3(2H)-ones and their antitumor activities

Zhou, J. & Chen, R., Jan 1 1999, In : Heteroatom Chemistry. 10, 3, p. 247-254 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
3 Scopus citations
2000

Separation of chiral phosphorus compounds on the substituted β-cyclodextrin stationary phase in normal-phase liquid chromatography

Chen, H., Lu, X. Y., Gao, R. Y., Zhou, J. & Wang, Q. S., Jan 1 2000, In : Chinese Journal of Chemistry. 18, 4, p. 533-536 4 p.

Research output: Contribution to journalArticle

6 Scopus citations
2002

Fluorescence resonance energy transfer between unnatural amino acids in a structurally modified dihydrofolate reductase

Anderson, R. D., Zhou, J. & Hecht, S. M., Aug 21 2002, In : Journal of the American Chemical Society. 124, 33, p. 9674-9675 2 p.

Research output: Contribution to journalArticle

56 Scopus citations
2003

Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: Synthesis and evaluation of their uptake inhibition at monoamine transporter sites

Zhou, J., Zhang, A., Kläss, T., Johnson, K. M., Wang, C. Z., Ye, Y. P. & Kozikowski, A. P., May 8 2003, In : Journal of Medicinal Chemistry. 46, 10, p. 1997-2007 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Synthesis and evaluation of iodine-123 labelled tricyclic tropanes as radioligands for the serotonin transporter

Quinlivan, M., Mattner, F., Papazian, V., Zhou, J., Katsifis, A., Emond, P., Chalon, S., Kozikowski, A., Guilloteau, D. & Kassiou, M., Oct 2003, In : Nuclear Medicine and Biology. 30, 7, p. 741-746 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Synthesis and pharmacological evaluation of (Z)-9-(Heteroarylmethylene)-7-azatricyclo[4.3.1.03,7]decanes: Thiophene analogues as potent norepinephrine transporter inhibitors

Zhou, J., Kläß, T., Zhang, A., Johnson, K. M., Wang, C. Z., Ye, Y. & Kozikowski, A. P., Oct 20 2003, In : Bioorganic and Medicinal Chemistry Letters. 13, 20, p. 3565-3569 5 p.

Research output: Contribution to journalArticle

11 Scopus citations
2004

Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model

Yamamoto, T., Hirasawa, S., Wroblewska, B., Grajkowska, E., Zhou, J., Kozikowski, A., Wroblewski, J. & Neale, J. H., Jul 1 2004, In : European Journal of Neuroscience. 20, 2, p. 483-494 12 p.

Research output: Contribution to journalArticle

77 Scopus citations

NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR

Olszewski, R. T., Bukhari, N., Zhou, J., Kozikowski, A. P., Wroblewski, J. T., Shamimi-Noori, S., Wroblewska, B., Bzdega, T., Vicini, S., Barton, F. B. & Neale, J. H., May 1 2004, In : Journal of neurochemistry. 89, 4, p. 876-885 10 p.

Research output: Contribution to journalArticle

103 Scopus citations

Piperidine-based nocaine/modafinil hybrid ligands as highly potent monoamine transporter inhibitors: Efficient drug discovery by rational lead hybridization

Zhou, J., He, R., Johnson, K. M., Ye, Y. & Kozikowski, A. P., Nov 18 2004, In : Journal of Medicinal Chemistry. 47, 24, p. 5821-5824 4 p.

Research output: Contribution to journalArticle

27 Scopus citations
2005

Discovery of novel conformationally constrained tropane-based biaryl and arylacetylene ligands as potent and selective norepinephrine transporter inhibitors and potential antidepressants

Zhou, J., Kläß, T., Johnson, K. M., Giberson, K. M. & Kozikowski, A. P., May 16 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 10, p. 2461-2465 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Glutamate carboxypeptidase II levels in rodent brain using [ 125I]DCIT quantitative autoradiography

Guilarte, T. R., McGlothan, J. L., Foss, C. A., Zhou, J., Heston, W. D., Kozikowski, A. P. & Pomper, M. G., Oct 28 2005, In : Neuroscience Letters. 387, 3, p. 141-144 4 p.

Research output: Contribution to journalArticle

21 Scopus citations
2006

Development of new brain imaging agents based upon nocaine-modafinil hybrid monoamine transporter inhibitors

Musachio, J. L., Hong, J., Ichise, M., Seneca, N., Brown, A. K., Liow, J. S., Halldin, C., Innis, R. B., Pike, V. W., He, R., Zhou, J. & Kozikowski, A. P., Jun 15 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 12, p. 3101-3104 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat

Zhong, C., Zhao, X., Van, K. C., Bzdega, T., Smyth, A., Zhou, J., Kozikowski, A. P., Jiang, J., O'Connor, W. T., Berman, R. F., Neale, J. H. & Lyeth, B. G., May 1 2006, In : Journal of neurochemistry. 97, 4, p. 1015-1025 11 p.

Research output: Contribution to journalArticle

70 Scopus citations

Role of the increased noradrenergic neurotransmission in drug self-administration

Wee, S., Wang, Z., He, R., Zhou, J., Kozikowski, A. P. & Woolverton, W. L., Apr 28 2006, In : Drug and Alcohol Dependence. 82, 2, p. 151-157 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Tandemly activated tRNAs as participants in protein synthesis

Wang, B., Zhou, J., Lodder, M., Anderson, R. D. & Hecht, S. M., May 19 2006, In : Journal of Biological Chemistry. 281, 20, p. 13865-13868 4 p.

Research output: Contribution to journalArticle

13 Scopus citations
2007

Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats

Yamamoto, T., Saito, O., Aoe, T., Bartolozzi, A., Sarva, J., Zhou, J., Kozikowski, A., Wroblewska, B., Bzdega, T. & Neale, J. H., Jan 1 2007, In : European Journal of Neuroscience. 25, 1, p. 147-158 12 p.

Research output: Contribution to journalArticle

41 Scopus citations

Positional assignment of differentially substituted bisaminoacylated pdCpAs

Maloney, D. J., Ghanem, N., Zhou, J. & Hecht, S. M., Sep 25 2007, In : Organic and Biomolecular Chemistry. 5, 19, p. 3135-3138 4 p.

Research output: Contribution to journalArticle

4 Scopus citations
2008

HDAC inhibitor increases histone H3 acetylation and reduces microglia inflammatory response following traumatic brain injury in rats

Zhang, B., West, E. J., Van, K. C., Gurkoff, G. G., Zhou, J., Zhang, X. M., Kozikowski, A. P. & Lyeth, B. G., Aug 21 2008, In : Brain Research. 1226, p. 181-191 11 p.

Research output: Contribution to journalArticle

93 Scopus citations

Inhibition of protein deacetylation by trichostatin A impairs microtubule-kinetochore attachment

Ma, Y., Cai, S., Lu, Q., Lu, X., Jiang, Q., Zhou, J. & Zhang, C., Oct 1 2008, In : Cellular and Molecular Life Sciences. 65, 19, p. 3100-3109 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain

Yamamoto, T., Kozikowski, A., Zhou, J. & Neale, J. H., Aug 1 2008, In : Molecular pain. 4, 31.

Research output: Contribution to journalArticle

24 Scopus citations

Phencyclidine and Dizocilpine Induced Behaviors Reduced by N-acetylaspartylglutamate Peptidase Inhibition via Metabotropic Glutamate Receptors

Olszewski, R. T., Wegorzewska, M. M., Monteiro, A. C., Krolikowski, K. A., Zhou, J., Kozikowski, A. P., Long, K., Mastropaolo, J., Deutsch, S. I. & Neale, J. H., Jan 1 2008, In : Biological Psychiatry. 63, 1, p. 86-91 6 p.

Research output: Contribution to journalArticle

51 Scopus citations
2010

The novel triple reuptake inhibitor JZAD-IV-22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties

Caldarone, B. J., Paterson, N. E., Zhou, J., Brunner, D., Kozikowski, A. P., Westphal, K. G. C., Korte-Bouws, G. A. H., Prins, J., Korte, S. M., Olivier, B. & Ghavami, A., Dec 1 2010, In : Journal of Pharmacology and Experimental Therapeutics. 335, 3, p. 762-770 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

Post-injury administration of NAAG peptidase inhibitor prodrug, PGI-02776, in experimental TBI

Feng, J. F., Van, K. C., Gurkoff, G. G., Kopriva, C., Olszewski, R. T., Song, M., Sun, S., Xu, M., Neale, J. H., Yuen, P. W., Lowe, D. A., Zhou, J. & Lyeth, B. G., Jun 13 2011, In : Brain Research. 1395, p. 62-73 12 p.

Research output: Contribution to journalArticle

21 Scopus citations
2012

5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP

Chen, H., Tsalkova, T., Mei, F. C., Hu, Y., Cheng, X. & Zhou, J., Jun 15 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 12, p. 4038-4043 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Exploration of synthetic approaches and pharmacological evaluation of PNU-69176E and its stereoisomer as 5-HT2C receptor allosteric modulators

Ding, C., Bremer, N. M., Smith, T. D., Seitz, P. K., Anastasio, N. C., Cunningham, K. A. & Zhou, J., Jul 18 2012, In : ACS chemical neuroscience. 3, 7, p. 538-545 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

NAAG peptidase inhibitor reduces cellular damage in a model of TBI with secondary hypoxia

Feng, J. F., Gurkoff, G. G., Van, K. C., Song, M., Lowe, D. A., Zhou, J. & Lyeth, B. G., Aug 21 2012, In : Brain Research. 1469, p. 144-152 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2013

A Combined Bioinformatics and Chemoinformatics Approach for Developing Asymmetric Bivalent AMPA Receptor Positive Allosteric Modulators as Neuroprotective Agents

Chen, H., Wang, C. Z., Ding, C., Wild, C., Copits, B., Swanson, G. T., Johnson, K. M. & Zhou, J., Feb 1 2013, In : ChemMedChem. 8, 2, p. 226-230 5 p.

Research output: Contribution to journalArticle

21 Scopus citations