Jianli Dong, MD, PhD, MMS

Director Molecular Immunology (PhD)

  • 1177 Citations
  • 18 h-Index
1991 …2019

Research output per year

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Research Output

2019

Genotypic and phenotypic variability of 22q11.2 microduplications: An institutional experience

Yu, A., Turbiville, D., Xu, F., Ray, J., Britt, A. D., Lupo, P., Jain, S., Shattuck, K., Robinson, S. S. & Dong, J., Jan 1 2019, (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

Iron Overload in an HFE Heterozygous Carrier: A Case Report and Literature Review

Turbiville, D., Du, X., Yo, J., Jana, B. & Dong, J., Apr 8 2019, In : Laboratory medicine. 50, 2, p. 212-217 6 p.

Research output: Contribution to journalArticle

2018

Developmental Defects Associated with DNA Copy Number Gain of Chromosome 2q33.1: A Case Report and Review of Literature

Gupta, A., Yo, J., Huang, G., Soong, L. & Dong, J., Mar 21 2018, In : Lab Medicine. 49, 2, p. 160-164 5 p.

Research output: Contribution to journalArticle

2017

Detection of an Underlying 22q11.2 Duplication in a Female Neonate With Trisomy 18

Turbiville, D. E., Wu, H. & Dong, J., Nov 8 2017, In : Laboratory Medicine. 48, 4, p. 372-375 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016
1 Scopus citations
2015

Persistence of müllerian duct structures in a genetic male with distal monosomy 10q

Tosur, M., Geary, C. A., Matalon, R., Radhakrishnan, R. S., Swischuk, L. E., Tarry, W. F., Dong, J. & Lee, P. D. K., Apr 1 2015, In : American Journal of Medical Genetics, Part A. 167, 4, p. 791-796 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014
1 Scopus citations

Do we need to worry about contamination by circulating fetal DNA?

Wu, H., Huang, G., Romay-Penabad, Z., Pierangeli, S. & Dong, J., May 1 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 5, p. e75-e77

Research output: Contribution to journalLetter

1 Scopus citations

Evaluation of INK4A promoter methylation using pyrosequencing and circulating cell-free DNA from patients with hepatocellular carcinoma

Huang, G., Krocker, J. D., Kirk, J. L., Merwat, S. N., Ju, H., Soloway, R. D., Wieck, L. R., Li, A., Okorodudu, A. O., Petersen, J. R., Abdulla, N. E., Duchini, A., Cicalese, L., Rastellini, C., Hu, P. C. & Dong, J., Jun 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 6, p. 899-909 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

K-type human endogenous retroviral elements in human melanoma

Rincon, L., Sedrak, MP., Sun, H., Garza, G., Kelly, B. & Dong, J., Oct 2014, In : Advances in Genomics and Genetics. p. 153-159

Research output: Contribution to journalArticle

2013

Human endogenous retroviral K element encodes fusogenic activity in melanoma cells

Huang, G., Li, Z., Wan, X., Wang, Y. & Dong, J., Jan 1 2013, In : Journal of Carcinogenesis. 12, 109032.

Research output: Contribution to journalArticle

17 Scopus citations

Lack of correlation between HERV-K expression and HIV-1 viral load in plasma specimens

Esqueda, D., Xu, F., Moore, Y., Yang, Z., Huang, G., Lennon, P. A., Hu, P. C. & Dong, J., May 30 2013, In : Annals of Clinical and Laboratory Science. 43, 2, p. 122-125 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Overcoming resistance to BRAF and MEK inhibitors by simultaneous suppression of CDK4

Dong, J., 2013, Melanoma - From Early Detection to Treatment. InTech

Research output: Chapter in Book/Report/Conference proceedingChapter

PCR and its variations

Loeffelholz, M. & Dong, J., Jan 1 2013, Advanced Techniques in Diagnostic Microbiology. Springer US, Vol. 9781461439707. p. 273-291 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

The potential importance of K type human endogenous retroviral element in melanoma biology

Dong, J., Huang, G., Imtiaz, R. & Xu, F., 2013, Melanoma - From Early Detection to Treatment. InTech

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

BK virus as a potential co-factor for HPV in the development of cervical neoplasia

Fraase, K., Hart, J., Wu, H., Pang, X., Ma, L., Grant, F., Li, A., Lennon, A., Hu, P. C. & Dong, J., Mar 1 2012, In : Annals of Clinical and Laboratory Science. 42, 2, p. 130-134 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Circulating DNA – important biomarker of cancer

Jin, D., Xie, S., Mo, Z., Liang, Y., Guo, R., Huang, G. & Dong, J., 2012, In : Journal of Molecular Biomarkers & Diagnosis.

Research output: Contribution to journalArticle

HIV-1 Genotyping and virtual phenotyping

Xu, F. & Dong, J., 2012, Modern Clinical Molecular Techniques. Springer

Research output: Chapter in Book/Report/Conference proceedingChapter

PCR and its variations

Loeffelholz, M. & Dong, J., 2012, Advanced Techniques in Diagnostic Microbiology. Springer

Research output: Chapter in Book/Report/Conference proceedingChapter

Quality management for molecular genetic testing: Clinical and Laboratory Standards Institute (CLSI) MM20-P

Chen, B., Dequeker, E., Dong, J., Emmadi, R., Gordon, JT., Howell, RM., Killeen, A., Levin, JD., Murray, CN., Pratt, VM., Rousseau, F., Stockley, TL. & Scheuner, M., 2012

Research output: Other contribution

Quantification of BK viral load

Wu, H. & Dong, J., 2012, Modern Clinical Molecular Techniques. Springer

Research output: Chapter in Book/Report/Conference proceedingChapter

Quantification of BK viral load

Wu, H. & Dong, J., Jul 1 2012, Modern Clinical Molecular Techniques. Springer New York, Vol. 9781461421702. p. 187-198 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA

Gulhati, P., Zaytseva, Y. Y., Valentino, J. D., Stevens, P. D., Kim, J. T., Sasazuki, T., Shirasawa, S., Lee, E. Y., Weiss, H. L., Dong, J., Gao, T. & Mark Evers, B., Sep 1 2012, In : Carcinogenesis. 33, 9, p. 1782-1790 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

The BRAFV600E causes widespread alterations in gene methylation in the genome of melanoma cells

Hou, P., Liu, D., Dong, J. & Xing, M., Jan 15 2012, In : Cell Cycle. 11, 2, p. 286-295 10 p.

Research output: Contribution to journalArticle

58 Scopus citations
2011

Establishing molecular testing in clinical laboratory environments; Proposed Guideline. Clinical and Laboratory Standards Institute (CLSI) MM19

Hall, L., Wilson, J., Bernard, K., Carbone, MP., Mubarak, HSE., Hallam, SE., Klein, RD., Pancholi, P., Schoonmaker, MM., Spector, EB., Vitazka, P., Boonyaratanakornkit, J., Bryant, B., Dong, J., Emmadi, R., Furtado, MR., Lacbawan, F., Martinez-Murillo, F., Schutzbank, TE., Selvarangan, R. & 3 others, Shyamala, V., Williams, LO. & Wu, A., 2011

Research output: Other contribution

Loss of p16INK4A expression in low-grade ovarian serous carcinomas

Schlosshauer, P. W., Deligdisch, L., Penault-Llorca, F., Fatemi, D., Qiao, R., Yao, S., Pearl, M., Yang, Z., Sheng, T. & Dong, J., Jan 1 2011, In : International Journal of Gynecological Pathology. 30, 1, p. 22-29 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Sequence-based fungal identification and classification

Dong, J., Loeffelholz, M. & McGinnis, M., 2011, Molecular Microbiology: Diagnostics Principles and Practice. American Society for Microbiology Press

Research output: Chapter in Book/Report/Conference proceedingChapter

Simultaneous knockdown of mutant BRAF and expression of INK4A in melanoma cells leads to potent growth inhibition and apoptosis

Dong, J. & Schwab, C., 2011, Treatment of Metastatic Melanoma.

Research output: Chapter in Book/Report/Conference proceedingChapter

Uncommon gnaq, MMP8, AKT3, EGFR, and PIK3R1 mutations in thyroid cancers

Murugan, A. K., Dong, J., Xie, J. & Xing, M., Jun 1 2011, In : Endocrine Pathology. 22, 2, p. 97-102 6 p.

Research output: Contribution to journalArticle

23 Scopus citations
2010

Expression of HERV-K correlates with status of MEKERK and p16INK4ACDK4 pathways in melanoma cells

Li, Z., Sheng, T., Wan, X., Liu, T., Wu, H. & Dong, J., Nov 1 2010, In : Cancer Investigation. 28, 10, p. 1031-1037 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

HCV genotype and subtype distribution of patient samples tested at University of Texas Medical Branch in Galveston, Texas

Clement, C., Yang, Z., Mayne, JC. & Dong, J., 2010, In : Journal of Molecular Genetics. p. 36-40

Research output: Contribution to journalArticle

Low prevalence of non-subtype B HIV-1 strains in the Texas prisoner population

Xu, F., Schwab, C., Yang, X., Weaver, S., Li, A., Sanborn, MR., Cloherty, GA. & Dong, J., 2010, In : Journal of Molecular Genetics. p. 41-44

Research output: Contribution to journalArticle

Monitoring of BK viral load in renal allograft recipients by real-time PCR assays

Bechert, C. J., Schnadig, V. J., Payne, D. A. & Dong, J., Feb 1 2010, In : American journal of clinical pathology. 133, 2, p. 242-250 9 p.

Research output: Contribution to journalReview article

57 Scopus citations

Simultaneous inhibition of MEK and CDK4 leads to potent apoptosis in human melanoma cells

Li, J., Xu, M., Yang, Z., Li, A. & Dong, J., Apr 1 2010, In : Cancer Investigation. 28, 4, p. 350-356 7 p.

Research output: Contribution to journalArticle

18 Scopus citations
2009
11 Scopus citations

False positive ultrasensitive HIV bDNA viral load results in diagnosis of perinatal HIV-infection in the era of low transmission

Patel, J. A., Anderson, E. & Dong, J., Oct 1 2009, In : Laboratory medicine. 40, 10, p. 611-614 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

MEK1 mutations, but not ERK2 mutations, occur in melanomas and colon carcinomas, but none in thyroid carcinomas

Murugan, A. K., Dong, J., Xie, J. & Xing, M., Jul 1 2009, In : Cell Cycle. 8, 13, p. 2122-2124 3 p.

Research output: Contribution to journalArticle

Open Access
47 Scopus citations

Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation

Estrada, Y., Dong, J. & Ossowski, L., Feb 1 2009, In : Pigment Cell and Melanoma Research. 22, 1, p. 66-76 11 p.

Research output: Contribution to journalArticle

2008

Emerging pathogens: Challenges and successes of molecular diagnostics

Dong, J., Olano, J. P., McBride, J. W. & Walker, D. H., May 2008, In : Journal of Molecular Diagnostics. 10, 3, p. 185-197 13 p.

Research output: Contribution to journalReview article

72 Scopus citations

HIV-1 genotypic resistance testing on low viral load specimens using the Abbott ViroSeq HIV-1 Genotyping System

Yang, Z., Morrison, R., Oates, C., Sarria, J., Patel, J., Habibi, A., Seyedjafari, R., Hu, P., Lennon, A., Li, A. & Dong, J., Dec 1 2008, In : Laboratory medicine. 39, 11, p. 671-673 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Simultaneous knockdown of BRAF and expression of INK4A in melanoma cells leads to potent growth inhibition and apoptosis

Zhao, Y., Zhang, Y., Yang, Z., Li, A. & Dong, J., Jun 6 2008, In : Biochemical and Biophysical Research Communications. 370, 3, p. 509-513 5 p.

Research output: Contribution to journalArticle

22 Scopus citations
2005

Effects on proliferation and melanogenesis by inhibition of mutant BRAF and expression of wild-type INK4A in melanoma cells

Rotolo, S., Diotti, R., Gordon, R. E., Qiao, R. F., Yao, Z., Phelps, R. G. & Dong, J., May 20 2005, In : International Journal of Cancer. 115, 1, p. 164-169 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Evidence against a role for SV40 in human mesothelioma

Manfredi, J. J., Dong, J., Liu, W. J., Resnick-Silverman, L., Qiao, R., Chahinian, P., Saric, M., Gibbs, A. R., Phillips, J. I., Murray, J., Axten, C. W., Nolan, R. P. & Aaronson, S. A., Apr 1 2005, In : Cancer Research. 65, 7, p. 2602-2609 8 p.

Research output: Contribution to journalArticle

89 Scopus citations
2003

BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma

Dong, J., Phelps, R. G., Qiao, R., Yao, S., Benard, O., Ronai, Z. & Aaronson, S. A., Jul 15 2003, In : Cancer Research. 63, 14, p. 3883-3885 3 p.

Research output: Contribution to journalArticle

256 Scopus citations

ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: Implications towards sensitization to apoptosis

Krasilnikov, M., Ivanov, V. N., Dong, J. & Ronai, Z., Jun 26 2003, In : Oncogene. 22, 26, p. 4092-4101 10 p.

Research output: Contribution to journalArticle

103 Scopus citations
2002

Carrier screening for mucolipidosis type IV in the American Ashkenazi Jewish population

Edelmann, L., Dong, J., Desnick, RJ. & Kornreich, R., 2002, In : Americal Journal of Human Genetics. p. 1023-1027

Research output: Contribution to journalArticle

27 Scopus citations

Carrier screening for mucolipidosis type IV in the American Ashkenazi Jewish population

Edelmann, L., Dong, J., Desnick, R. J. & Kornreich, R., Jan 1 2002, In : American Journal of Human Genetics. 70, 4, p. 1023-1027 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Familial dysautonomia: Detection of the IKBKAP IVS20+6T → C and R696P mutations and frequencies among Ashkenazi Jews

Dong, J., Edelmann, L., Bajwa, A. M., Kornreich, R. & Desnick, R. J., Jul 1 2002, In : American Journal of Medical Genetics. 110, 3, p. 253-257 5 p.

Research output: Contribution to journalArticle

47 Scopus citations

Familial dysautonomia: detection of the IKAP(IVS20+6T->C) and R696P mutations and frequencies among Ashkenazi Jews

Dong, J., Edelman, L., Bajwa, AM., Kornreich, R. & Desnick, RJ., 2002, In : American Journal of Medical Genetics. p. 253-257

Research output: Contribution to journalArticle

2001

Nonradioactive detection of the common Connexin 26 167delT and 35delG mutations and frequencies among Ashkenazi Jews

Dong, J., Katz, D. R., Eng, C. M., Kornreich, R. & Desnick, R. J., Jan 1 2001, In : Molecular Genetics and Metabolism. 73, 2, p. 160-163 4 p.

Research output: Contribution to journalArticle

17 Scopus citations