Jianli Dong, MD, PhD, MMS

Director Molecular Immunology (PhD)

  • 1211 Citations
  • 18 h-Index
1991 …2019
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1991 2019

  • 1211 Citations
  • 18 h-Index
  • 44 Article
  • 10 Chapter
  • 2 Other contribution
Filter
Article
2019

Genotypic and phenotypic variability of 22q11.2 microduplications: An institutional experience

Yu, A., Turbiville, D., Xu, F., Ray, J., Britt, A. D., Lupo, P., Jain, S., Shattuck, K., Robinson, S. S. & Dong, J., Jan 1 2019, (Accepted/In press) In : American Journal of Medical Genetics, Part A.

Research output: Contribution to journalArticle

Cardiovascular Abnormalities
Phenotype
Central Nervous System
Parturition
Newborn Infant

Iron Overload in an HFE Heterozygous Carrier: A Case Report and Literature Review

Turbiville, D., Du, X., Yo, J., Jana, B. & Dong, J., Apr 8 2019, In : Laboratory medicine. 50, 2, p. 212-217 6 p.

Research output: Contribution to journalArticle

Iron Overload
Hemochromatosis
Iron
Mutation
Alanine Transaminase
2018

Developmental Defects Associated with DNA Copy Number Gain of Chromosome 2q33.1: A Case Report and Review of Literature

Gupta, A., Yo, J., Huang, G., Soong, L. & Dong, J., Mar 21 2018, In : Lab Medicine. 49, 2, p. 160-164 5 p.

Research output: Contribution to journalArticle

Chromosomes
Genes
Apoptosis
Caspases
Defects
2017
1 Citation (Scopus)

Detection of an Underlying 22q11.2 Duplication in a Female Neonate With Trisomy 18

Turbiville, D. E., Wu, H. & Dong, J., Nov 8 2017, In : Laboratory Medicine. 48, 4, p. 372-375 4 p.

Research output: Contribution to journalArticle

Microarrays
Newborn Infant
Chromosomes
Chromosomes, Human, Pair 18
Karyotyping
2016
1 Citation (Scopus)
Viruses
Hepacivirus
Genotype
Clinical laboratories
Geographical regions
2015
8 Citations (Scopus)

Persistence of müllerian duct structures in a genetic male with distal monosomy 10q

Tosur, M., Geary, C., Matalon, R., Radhakrishnan, R., Swischuk, L. E., Tarry, W. F., Dong, J. & Lee, P., Apr 1 2015, In : American Journal of Medical Genetics, Part A. 167, 4, p. 791-796 6 p.

Research output: Contribution to journalArticle

Hormones
Testosterone
Rectal Fistula
Imperforate Anus
Orchiopexy
2014
1 Citation (Scopus)
BK Virus
Validation Studies
Viral Load
Viruses
Real-Time Polymerase Chain Reaction
1 Citation (Scopus)

Do we need to worry about contamination by circulating fetal DNA?

Wu, H., Huang, G., Romay-Penabad, Z., Pierangeli, S. & Dong, J., May 1 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 5

Research output: Contribution to journalArticle

DNA Contamination
Prenatal Diagnosis
Fetus
Pregnancy
DNA
20 Citations (Scopus)

Evaluation of INK4A promoter methylation using pyrosequencing and circulating cell-free DNA from patients with hepatocellular carcinoma

Huang, G., Krocker, J. D., Kirk, J. L., Merwat, S. N., Ju, H., Soloway, R. D., Wieck, L. R., Li, A., Okorodudu, A., Petersen, J. R., Abdulla, N. E., Duchini, A., Cicalese, L., Rastellini, C., Hu, P. C. & Dong, J., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 6, p. 899-909 11 p.

Research output: Contribution to journalArticle

Methylation
Cyclin-Dependent Kinases
Hepatocellular Carcinoma
DNA
Biomarkers

K-type human endogenous retroviral elements in human melanoma

Rincon, L., Sedrak, MP., Sun, H., Garza, G., Kelly, B. & Dong, J., Oct 2014, In : Advances in Genomics and Genetics. p. 153-159

Research output: Contribution to journalArticle

2013
16 Citations (Scopus)

Human endogenous retroviral K element encodes fusogenic activity in melanoma cells

Huang, G., Li, Z., Wan, X., Wang, Y. & Dong, J., Jan 1 2013, In : Journal of Carcinogenesis. 12, 109032.

Research output: Contribution to journalArticle

Endogenous Retroviruses
Melanoma
Cell Fusion
Molecular Evolution
Loss of Heterozygosity
7 Citations (Scopus)

Lack of correlation between HERV-K expression and HIV-1 viral load in plasma specimens

Esqueda, D., Xu, F., Moore, Y., Yang, Z., Huang, G., Lennon, P. A., Hu, P. C. & Dong, J., 2013, In : Annals of Clinical and Laboratory Science. 43, 2, p. 122-125 4 p.

Research output: Contribution to journalArticle

Endogenous Retroviruses
Deoxyribonuclease I
Viral Load
HIV-1
Chemical activation
2012
6 Citations (Scopus)

BK virus as a potential co-factor for HPV in the development of cervical neoplasia

Fraase, K., Hart, J., Wu, H., Pang, X., Ma, L., Grant, F., Li, A., Lennon, A., Hu, P. C. & Dong, J., Mar 2012, In : Annals of Clinical and Laboratory Science. 42, 2, p. 130-134 5 p.

Research output: Contribution to journalArticle

BK Virus
Viruses
Uterine Cervical Neoplasms
Neoplasms
Polyomavirus Infections

Circulating DNA – important biomarker of cancer

Jin, D., Xie, S., Mo, Z., Liang, Y., Guo, R., Huang, G. & Dong, J., 2012, In : Journal of Molecular Biomarkers & Diagnosis.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA

Gulhati, P., Zaytseva, Y. Y., Valentino, J. D., Stevens, P. D., Kim, J. T., Sasazuki, T., Shirasawa, S., Lee, E. Y., Weiss, H. L., Dong, J., Gao, T. & Mark Evers, B., Sep 2012, In : Carcinogenesis. 33, 9, p. 1782-1790 9 p.

Research output: Contribution to journalArticle

Sirolimus
Colorectal Neoplasms
Phosphatidylinositol 3-Kinase
Therapeutics
sorafenib
57 Citations (Scopus)

The BRAF V600E causes widespread alterations in gene methylation in the genome of melanoma cells

Hou, P., Liu, D., Dong, J. & Xing, M., Jan 15 2012, In : Cell Cycle. 11, 2, p. 286-295 10 p.

Research output: Contribution to journalArticle

Methylation
Melanoma
Genome
Genes
CpG Islands
2011
15 Citations (Scopus)

Loss of p16INK4A expression in low-grade ovarian serous carcinomas

Schlosshauer, P. W., Deligdisch, L., Penault-Llorca, F., Fatemi, D., Qiao, R., Yao, S., Pearl, M., Yang, Z., Sheng, T. & Dong, J., Jan 2011, In : International Journal of Gynecological Pathology. 30, 1, p. 22-29 8 p.

Research output: Contribution to journalArticle

Carcinoma
Neoplasms
Extracellular Signal-Regulated MAP Kinases
Mutation
Tumor Suppressor Proteins
23 Citations (Scopus)

Uncommon gnaq, MMP8, AKT3, EGFR, and PIK3R1 mutations in thyroid cancers

Murugan, A. K., Dong, J., Xie, J. & Xing, M., Jun 2011, In : Endocrine Pathology. 22, 2, p. 97-102 6 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Mutation
erbB-1 Genes
Genes
Single Nucleotide Polymorphism
2010
11 Citations (Scopus)

Expression of HERV-K correlates with status of MEKERK and p16INK4ACDK4 pathways in melanoma cells

Li, Z., Sheng, T., Wan, X., Liu, T., Wu, H. & Dong, J., Nov 2010, In : Cancer Investigation. 28, 10, p. 1031-1037 7 p.

Research output: Contribution to journalArticle

Endogenous Retroviruses
Melanoma
MAP Kinase Signaling System
Cell Shape
Melanins

HCV genotype and subtype distribution of patient samples tested at University of Texas Medical Branch in Galveston, Texas

Clement, C., Yang, Z., Mayne, JC. & Dong, J., 2010, In : Journal of Molecular Genetics. p. 36-40

Research output: Contribution to journalArticle

Low prevalence of non-subtype B HIV-1 strains in the Texas prisoner population

Xu, F., Schwab, C., Yang, X., Weaver, S., Li, A., Sanborn, MR., Cloherty, GA. & Dong, J., 2010, In : Journal of Molecular Genetics. p. 41-44

Research output: Contribution to journalArticle

57 Citations (Scopus)

Monitoring of BK viral load in renal allograft recipients by real-time PCR assays

Bechert, C. J., Schnadig, V. J., Payne, D. A. & Dong, J., Feb 2010, In : American Journal of Clinical Pathology. 133, 2, p. 242-250 9 p.

Research output: Contribution to journalArticle

BK Virus
Viral Load
Allografts
Real-Time Polymerase Chain Reaction
Kidney
18 Citations (Scopus)

Simultaneous inhibition of MEK and CDK4 leads to potent apoptosis in human melanoma cells

Li, J., Xu, M., Yang, Z., Li, A. & Dong, J., Apr 2010, In : Cancer Investigation. 28, 4, p. 350-356 7 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase Kinases
Melanoma
Apoptosis
MAP Kinase Signaling System
Up-Regulation
2009
11 Citations (Scopus)
Papillomaviridae
Fallopian Tubes
Carcinoma in Situ
Cervix Uteri
Squamous Cell Carcinoma
4 Citations (Scopus)

False positive ultrasensitive HIV bDNA viral load results in diagnosis of perinatal HIV-infection in the era of low transmission

Patel, J., Anderson, E. & Dong, J., Oct 2009, In : Laboratory Medicine. 40, 10, p. 611-614 4 p.

Research output: Contribution to journalArticle

Viral DNA
Viral Load
HIV Infections
HIV
DNA
47 Citations (Scopus)

MEK1 mutations, but not ERK2 mutations, occur in melanomas and colon carcinomas, but none in thyroid carcinomas

Murugan, A. K., Dong, J., Xie, J. & Xing, M., Jul 1 2009, In : Cell Cycle. 8, 13, p. 2122-2124 3 p.

Research output: Contribution to journalArticle

Thyroid Neoplasms
Melanoma
Colon
Carcinoma
Colonic Neoplasms
2008
71 Citations (Scopus)

Emerging pathogens: Challenges and successes of molecular diagnostics

Dong, J., Olano, J., McBride, J. & Walker, D., May 2008, In : Journal of Molecular Diagnostics. 10, 3, p. 185-197 13 p.

Research output: Contribution to journalArticle

Molecular Pathology
Sin Nombre virus
Infectious Disease Medicine
Bacillary Angiomatosis
Anaplasmosis
7 Citations (Scopus)

HIV-1 genotypic resistance testing on low viral load specimens using the Abbott ViroSeq HIV-1 Genotyping System

Yang, Z., Morrison, R., Oates, C., Sarria, J., Patel, J., Habibi, A., Seyedjafari, R., Hu, P., Lennon, A., Li, A. & Dong, J., 2008, In : Laboratory Medicine. 39, 11, p. 671-673 3 p.

Research output: Contribution to journalArticle

Viral Load
HIV-1
RNA
HIV
Testing
22 Citations (Scopus)

Simultaneous knockdown of BRAF and expression of INK4A in melanoma cells leads to potent growth inhibition and apoptosis

Zhao, Y., Zhang, Y., Yang, Z., Li, A. & Dong, J., Jun 6 2008, In : Biochemical and Biophysical Research Communications. 370, 3, p. 509-513 5 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Melanoma
Complementary DNA
Apoptosis
Cyclin D
2005
18 Citations (Scopus)

Effects on proliferation and melanogenesis by inhibition of mutant BRAF and expression of wild-type INK4A in melanoma cells

Rotolo, S., Diotti, R., Gordon, R. E., Qiao, R. F., Yao, Z., Phelps, R. G. & Dong, J., May 20 2005, In : International Journal of Cancer. 115, 1, p. 164-169 6 p.

Research output: Contribution to journalArticle

Melanoma
RNA Interference
benfluorex
Growth
Microphthalmia-Associated Transcription Factor
89 Citations (Scopus)

Evidence against a role for SV40 in human mesothelioma

Manfredi, J. J., Dong, J., Liu, W. J., Resnick-Silverman, L., Qiao, R., Chahinian, P., Saric, M., Gibbs, A. R., Phillips, J. I., Murray, J., Axten, C. W., Nolan, R. P. & Aaronson, S. A., Apr 1 2005, In : Cancer Research. 65, 7, p. 2602-2609 8 p.

Research output: Contribution to journalArticle

Polyomavirus Transforming Antigens
Viral Tumor Antigens
Mesothelioma
Cell Line
Neoplasms
2003
253 Citations (Scopus)

BRAF oncogenic mutations correlate with progression rather than initiation of human melanoma

Dong, J., Phelps, R. G., Qiao, R., Yao, S., Benard, O., Ronai, Z. & Aaronson, S. A., Jul 15 2003, In : Cancer Research. 63, 14, p. 3883-3885 3 p.

Research output: Contribution to journalArticle

Melanoma
Mutation
Growth
Viverridae
Pigmented Nevus
103 Citations (Scopus)

ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: Implications towards sensitization to apoptosis

Krasilnikov, M., Ivanov, V. N., Dong, J. & Ronai, Z., Jun 26 2003, In : Oncogene. 22, 26, p. 4092-4101 10 p.

Research output: Contribution to journalArticle

Transducers
Phosphatidylinositol 3-Kinases
Human Activities
Melanoma
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
2002
27 Citations (Scopus)

Carrier screening for mucolipidosis type IV in the American Ashkenazi Jewish population

Edelmann, L., Dong, J., Desnick, R. J. & Kornreich, R., 2002, In : American Journal of Human Genetics. 70, 4, p. 1023-1027 5 p.

Research output: Contribution to journalArticle

Mucolipidoses
Mutation
Population
Alleles
Multiplex Polymerase Chain Reaction
27 Citations (Scopus)

Carrier screening for mucolipidosis type IV in the American Ashkenazi Jewish population

Edelmann, L., Dong, J., Desnick, RJ. & Kornreich, R., 2002, In : Americal Journal of Human Genetics. p. 1023-1027

Research output: Contribution to journalArticle

47 Citations (Scopus)

Familial dysautonomia: Detection of the IKBKAP IVS20+6T → C and R696P mutations and frequencies among Ashkenazi Jews

Dong, J., Edelmann, L., Bajwa, A. M., Kornreich, R. & Desnick, R. J., Jul 1 2002, In : American Journal of Medical Genetics. 110, 3, p. 253-257 5 p.

Research output: Contribution to journalArticle

Familial Dysautonomia
Jews
Mutation Rate
Mutation
Oligonucleotides

Familial dysautonomia: detection of the IKAP(IVS20+6T->C) and R696P mutations and frequencies among Ashkenazi Jews

Dong, J., Edelman, L., Bajwa, AM., Kornreich, R. & Desnick, RJ., 2002, In : American Journal of Medical Genetics. p. 253-257

Research output: Contribution to journalArticle

2001
17 Citations (Scopus)

Nonradioactive detection of the common Connexin 26 167delT and 35delG mutations and frequencies among Ashkenazi Jews

Dong, J., Katz, D. R., Eng, C. M., Kornreich, R. & Desnick, R. J., 2001, In : Molecular Genetics and Metabolism. 73, 2, p. 160-163 4 p.

Research output: Contribution to journalArticle

Jews
Connexins
Deafness
Mutation Rate
Screening

Non-radioactive detection of the common connexin 26 167delT and 35delG mutations and frequencies among Ashkenazi Jews

Dong, J., Katz, DR., Eng, CM., Kornreich, R. & Desnick, RJ., 2001, In : Molecular Genetics and Metabolism. p. 160-163

Research output: Contribution to journalArticle

2000
45 Citations (Scopus)

Identification of PATCHED mutations in medulloblastomas by direct sequencing.

Dong, J., Gailani, M. R., Pomeroy, S. L., Reardon, D. & Bale, A. E., Jul 2000, In : Human Mutation. 16, 1, p. 89-90 2 p.

Research output: Contribution to journalArticle

Medulloblastoma
Mutation
Mutation Rate
Alleles
Protein Splicing
1999
4 Citations (Scopus)

Tissue-specific requirements for a phosphorylation site in the Fushi tarazu homeodomain

Dong, J. & Krause, H. M., 1999, In : Development Genes and Evolution. 209, 7, p. 427-431 5 p.

Research output: Contribution to journalArticle

nervous system
phosphorylation
Phosphorylation
central nervous system
segmentation
1998
14 Citations (Scopus)

A phosphorylation site in the Ftz homeodomain is required for activity

Dong, J., Hung, L. H., Strome, R. & Krause, H. M., Apr 15 1998, In : EMBO Journal. 17, 8, p. 2308-2318 11 p.

Research output: Contribution to journalArticle

Phosphorylation
Embryonic Structures
Viperidae
Fushi Tarazu Transcription Factors
Substitution reactions
35 Citations (Scopus)

Dynamic changes in the functions of Odd-skipped during early Drosophila embryogenesis

Dréan, B. S. L., Nasiadka, A., Dong, J. & Krause, H. M., 1998, In : Development. 125, 23, p. 4851-4861 11 p.

Research output: Contribution to journalArticle

Drosophila
Embryonic Development
Genes
Transcription Factors
Embryonic Structures
1991
62 Citations (Scopus)

Islet cell and extrapancreatic expression of the LIM domain homeobox gene isl-1

Dong, J., Asa, S. L. & Drucker, D. J., 1991, In : Molecular Endocrinology. 5, 11, p. 1633-1641 9 p.

Research output: Contribution to journalArticle

Homeobox Genes
Islets of Langerhans
Pheochromocytoma
Insulin
Kidney