Jiaren Sun, MD, PhD, MS

  • 7230 Citations
  • 23 h-Index
1993 …2020
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Research Output 1993 2019

  • 7230 Citations
  • 23 h-Index
  • 56 Article
  • 1 Comment/debate
  • 1 Editorial
  • 1 Review article
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Article
2019

An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses

Li, G., Adam, A., Luo, H., Shan, C., Cao, Z., Fontes-Garfias, C. R., Sarathy, V. V., Teleki, C., Winkelmann, E. R., Liang, Y., Sun, J., Bourne, N., Barrett, A. D. T., Shi, P. Y. & Wang, T., Dec 1 2019, In : npj Vaccines. 4, 1, 48.

Research output: Contribution to journalArticle

Open Access
Mutant Proteins
Antiviral Agents
Attenuated Vaccines
Flavivirus
Zika Virus
4 Citations (Scopus)

IL-33 induces immunosuppressive neutrophils via a type 2 innate lymphoid cell/IL-13/STAT6 axis and protects the liver against injury in LCMV infection-induced viral hepatitis

Liang, Y., Yi, P., Yuan, D. M. K., Jie, Z., Kwota, Z., Soong, L., Cong, Y. & Sun, J., Feb 1 2019, In : Cellular and Molecular Immunology. 16, 2, p. 126-137 12 p.

Research output: Contribution to journalArticle

STAT6 Transcription Factor
Lymphocytic choriomeningitis virus
Interleukin-13
Virus Diseases
Immunosuppressive Agents
2 Citations (Scopus)

Interleukin-33 Promotes REG3γ Expression in Intestinal Epithelial Cells and Regulates Gut Microbiota

Xiao, Y., Huang, X., Zhao, Y., Chen, F., Sun, M., Yang, W., Chen, L., Yao, S., Peniche-Trujillo, A-G., Dann-Grice, S., Sun, J., Golovko, G., Fofanov, Y., Miao, Y., Liu, Z., Chen, D. & Cong, Y., Jan 1 2019, In : CMGH. 8, 1, p. 21-36 16 p.

Research output: Contribution to journalArticle

Open Access
Epithelial Cells
Citrobacter rodentium
Homeostasis
Gastrointestinal Microbiome
Interleukin-33
1 Citation (Scopus)

Redox regulation of hepatic NLRP3 inflammasome activation and immune dysregulation in trichloroethene-mediated autoimmunity

Wang, H., Wang, G., Liang, Y., Du, X., Boor, P. J., Sun, J. & Khan, M., Nov 1 2019, In : Free Radical Biology and Medicine. 143, p. 223-231 9 p.

Research output: Contribution to journalArticle

Inflammasomes
Trichloroethylene
Autoimmunity
Oxidation-Reduction
Chemical activation
2018
22 Citations (Scopus)

In Inflamed Intestinal Tissues and Epithelial Cells, Interleukin 22 Signaling Increases Expression of H19 Long Noncoding RNA, Which Promotes Mucosal Regeneration

Geng, H., Bu, H. F., Liu, F., Wu, L., Pfeifer, K., Chou, P. M., Wang, X., Sun, J., Lu, L., Pandey, A., Bartolomei, M. S., De Plaen, I. G., Wang, P., Yu, J., Qian, J. & Tan, X. D., Jul 1 2018, In : Gastroenterology. 155, 1, p. 144-155 12 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Regeneration
Epithelial Cells
Dextran Sulfate
Lipopolysaccharides
2017
2 Citations (Scopus)

A tightly regulated IL-22 response maintains immune functions and homeostasis in systemic viral infection

Yi, P., Liang, Y., Yuan, D. M. K., Jie, Z., Kwota, Z., Chen, Y., Cong, Y., Fan, X. & Sun, J., Dec 1 2017, In : Scientific Reports. 7, 1, 3857.

Research output: Contribution to journalArticle

Virus Diseases
Homeostasis
Interleukin-23
T-Lymphocytes
1-Phosphatidylinositol 4-Kinase
5 Citations (Scopus)

Choroidal γδ T cells in protection against retinal pigment epithelium and retinal injury

Zhao, Z., Liang, Y., Liu, Y., Xu, P., Flamme-Wiese, M. J., Sun, D., Sun, J., Mullins, R. F., Chen, Y. & Cai, J., Nov 1 2017, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31, 11, p. 4903-4916 14 p.

Research output: Contribution to journalArticle

Retinal Pigments
Cytoprotection
T-cells
Retinal Pigment Epithelium
T-Lymphocytes
11 Citations (Scopus)
Optic Nerve Injuries
Nerve Crush
CXC Chemokines
Chemokine Receptors
Optic Nerve
31 Citations (Scopus)

Outcomes of Congenital Zika Disease Depend on Timing of Infection and Maternal-Fetal Interferon Action

Chen, J., Liang, Y., Yi, P., Xu, L., Hawkins, H. K., Rossi, S., Soong, L., Cai, J., Menon, R. & Sun, J., Nov 7 2017, In : Cell Reports. 21, 6, p. 1588-1599 12 p.

Research output: Contribution to journalArticle

Viruses
Interferons
Mothers
Infection
Fetus
9 Citations (Scopus)

Priming and activation of inflammasome by canarypox virus vector alvac via the CGAS/IFI16-sting-type I IFN pathway and AIM2 sensor

Liu, F., Niu, Q., Fan, X., Liu, C., Zhang, J., Wei, Z., Hou, W., Kanneganti, T. D., Robb, M. L., Kim, J. H., Michael, N. L., Sun, J., Soong, L. & Hu, H., Nov 1 2017, In : Journal of Immunology. 199, 9, p. 3293-3305 13 p.

Research output: Contribution to journalArticle

Canarypox virus
Inflammasomes
Bites and Stings
Vaccines
Clustered Regularly Interspaced Short Palindromic Repeats
11 Citations (Scopus)

Retinoic acid regulates immune responses by promoting IL-22 and modulating S100 proteins in viral hepatitis

Jie, Z., Liang, Y., Yi, P., Tang, H., Soong, L., Cong, Y., Zhang, K. & Sun, J., May 1 2017, In : Journal of Immunology. 198, 9, p. 3448-3460 13 p.

Research output: Contribution to journalArticle

S100 Proteins
Tretinoin
Hepatitis
T-Lymphocytes
Liver
2 Citations (Scopus)

Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice

Soong, L., Shelite, T., Xing, Y., Kodakandla, H., Liang, Y., Trent, B., Horton, P., Smith, K. C., Zhao, Z., Sun, J., Bouyer, D. & Cai, J., Jul 24 2017, In : PLoS Neglected Tropical Diseases. 11, 7, e0005765.

Research output: Contribution to journalArticle

Orientia tsutsugamushi
Scrub Typhus
Blood Vessels
Phagocytes
Infection
21 Citations (Scopus)

Viral retinopathy in experimental models of zika infection

Zhao, Z., Yang, M., Azar, S. R., Soong, L., Weaver, S., Sun, J., Chen, Y., Rossi, S. & Cai, J., Aug 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 10, p. 4075-4085 11 p.

Research output: Contribution to journalArticle

Theoretical Models
Infection
Retinal Pigments
Retina
Neuroglia
2016
16 Citations (Scopus)
Orientia tsutsugamushi
Apoptosis
Kidney
Endothelial Cells
Wounds and Injuries
34 Citations (Scopus)

MTOR mediates IL-23 induction of neutrophil IL-17 and IL-22 production

Chen, F., Cao, A., Yao, S., Evans-Marin, H. L., Liu, H., Wu, W., Carlsen, E. D., Dann-Grice, S., Soong, L., Sun, J., Zhao, Q. & Cong, Y., May 15 2016, In : Journal of Immunology. 196, 10, p. 4390-4399 10 p.

Research output: Contribution to journalArticle

Interleukin-23
Interleukin-17
Neutrophils
Colitis
Microbiota
10 Citations (Scopus)

Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection

Liu, F., Fan, X., Auclair, S., Ferguson, M., Sun, J., Soong, L., Hou, W., Redfield, R. R., Birx, D. L., Ratto-Kim, S., Robb, M. L., Kim, J. H., Michael, N. L. & Hu, H., Jun 1 2016, In : PLoS Pathogens. 12, 6, e1005663.

Research output: Contribution to journalArticle

Candida albicans
HIV Infections
HIV-1
HIV
T-Lymphocytes
2015
22 Citations (Scopus)

Exchange protein directly activated by cAMP modulates regulatory T-cell-mediated immunosuppression

Almahariq, M., Mei, F. C., Wang, H., Cao, A. T., Yao, S., Soong, L., Sun, J., Cong, Y., Chen, J. & Cheng, X., Jan 15 2015, In : Biochemical Journal. 465, p. 295-303 9 p.

Research output: Contribution to journalArticle

T-cells
Regulatory T-Lymphocytes
Immunosuppression
Pharmacology
T-Lymphocytes
19 Citations (Scopus)

IL-33 promotes innate IFN-γ production and modulates dendritic cell response in LCMV-induced hepatitis in mice

Liang, Y., Jie, Z., Hou, L., Yi, P., Wang, W., Kwota, Z., Salvato, M., de Waal Malefyt, R., Soong, L. & Sun, J., 2015, (Accepted/In press) In : European Journal of Immunology.

Research output: Contribution to journalArticle

Lymphocytic choriomeningitis virus
Dendritic Cells
Hepatitis
T-Lymphocytes
Interleukin-17
10 Citations (Scopus)

Immune and non-immune responses to hepatitis C virus infection

Sun, J., Rajsbaum Gorodezky, R. & Yi, M. K., Oct 14 2015, In : World Journal of Gastroenterology. 21, 38, p. 10739-10748 10 p.

Research output: Contribution to journalArticle

Virus Diseases
Hepacivirus
Virus Replication
Antiviral Agents
T-Lymphocytes
18 Citations (Scopus)

Interactions between Neutrophils and Leishmania braziliensis Amastigotes Facilitate Cell Activation and Parasite Clearance

Carlsen, E. D., Jie, Z., Liang, Y., Henard, C. A., Hay, C., Sun, J., de Matos Guedes, H. & Soong, L., Feb 27 2015, (Accepted/In press) In : Journal of Innate Immunity.

Research output: Contribution to journalArticle

Leishmania braziliensis
Parasites
Neutrophils
Neutrophil Activation
Leishmania
16 Citations (Scopus)
Interleukin-7
Interferon Type I
Hepatitis
Homeostasis
T-Lymphocytes
4 Citations (Scopus)

γδ T cells in infection and autoimmunity

Hou, L., Wang, T. & Sun, J., Feb 17 2015, (Accepted/In press) In : International Immunopharmacology.

Research output: Contribution to journalArticle

Autoimmunity
Interleukin-17
T-Lymphocytes
Infection
Carcinogenesis
2014
6 Citations (Scopus)
Hepatocyte Growth Factor
Hepatitis
Antiviral Agents
Pathology
Liver
24 Citations (Scopus)

Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection

Jie, Z., Liang, Y., Hou, L., Dong, C., Iwakura, Y., Soong, L., Cong, Y. & Sun, J., Apr 1 2014, In : Journal of Immunology. 192, 7, p. 3289-3300 12 p.

Research output: Contribution to journalArticle

Interleukin-17
Virus Diseases
Lymphocytes
T-Lymphocytes
Liver
18 Citations (Scopus)
Orientia tsutsugamushi
Scrub Typhus
Angiopoietin-2
Pathology
Angiopoietin-1
17 Citations (Scopus)

γδ T cells as a major source of IL-17 production during age-dependent RPE degeneration

Zhao, Z., Xu, P., Jie, Z., Zuo, Y., Yu, B., Soong, L., Sun, J., Chen, Y. & Cai, J., 2014, In : Investigative Ophthalmology and Visual Science. 55, 10, p. 6580-6589 10 p.

Research output: Contribution to journalArticle

Interleukin-17
Retinal Pigment Epithelium
Macular Degeneration
T-Lymphocytes
Retina
2013
35 Citations (Scopus)

Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis

Hou, L., Jie, Z., Desai, M., Liang, Y., Soong, L., Wang, T. & Sun, J., Jan 15 2013, In : Journal of Immunology. 190, 2, p. 621-629 9 p.

Research output: Contribution to journalArticle

Interleukin-17
Adaptive Immunity
Hepatitis
Interleukin-7
T-Lymphocytes
48 Citations (Scopus)

IL-33 induces nuocytes and modulates liver injury in viral hepatitis

Liang, Y., Jie, Z., Hou, L., Aguilar-Valenzuela, R., Vu, D., Soong, L. & Sun, J., Jun 1 2013, In : Journal of Immunology. 190, 11, p. 5666-5675 10 p.

Research output: Contribution to journalArticle

Hepatitis
Liver
Wounds and Injuries
Macrophages
Adenoviridae
2012
2408 Citations (Scopus)

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., Ait-Si-Ali, S., Akematsu, T., Akira, S., Al-Younes, H. M., Al-Zeer, M. A., Albert, M. L., Albin, R. L., Alegre-Abarrategui, J. & 1,249 others, Aleo, M. F., Alirezaei, M., Almasan, A., Almonte-Becerril, M., Amano, A., Amaravadi, R., Amarnath, S., Amer, A. O., Andrieu-Abadie, N., Anantharam, V., Ann, D. K., Anoopkumar-Dukie, S., Aoki, H., Apostolova, N., Arancia, G., Aris, J. P., Asanuma, K., Asare, N. Y. O., Ashida, H., Askanas, V., Askew, D. S., Auberger, P., Baba, M., Backues, S. K., Baehrecke, E. H., Bahr, B. A., Bai, X. Y., Bailly, Y., Baiocchi, R., Baldini, G., Balduini, W., Ballabio, A., Bamber, B. A., Bampton, E. T. W., Bánhegyi, G., Bartholomew, C. R., Bassham, D. C., Bast, R. C., Batoko, H., Bay, B. H., Beau, I., Béchet, D. M., Begley, T. J., Behl, C., Behrends, C., Bekri, S., Bellaire, B., Bendall, L. J., Benetti, L., Berliocchi, L., Bernardi, H., Bernassola, F., Besteiro, S., Bhatia-Kissova, I., Bi, X., Biard-Piechaczyk, M., Blum, J. S., Boise, L. H., Bonaldo, P., Boone, D. L., Bornhauser, B. C., Bortoluci, K. R., Bossis, I., Bost, F., Bourquin, J. P., Boya, P., Boyer-Guittaut, M., Bozhkov, P. V., Brady, N. R., Brancolini, C., Brech, A., Brenman, J. E., Brennand, A., Bresnick, E. H., Brest, P., Bridges, D., Bristol, M. L., Brookes, P. S., Brown, E. J., Brumell, J. H., Brunetti-Pierri, N., Brunk, U. T., Bulman, D. E., Bultman, S. J., Bultynck, G., Burbulla, L. F., Bursch, W., Butchar, J. P., Buzgariu, W., Bydlowski, S. P., Cadwell, K., Cahová, M., Cai, D., Cai, J., Cai, Q., Calabretta, B., Calvo-Garrido, J., Camougrand, N., Campanella, M., Campos-Salinas, J., Candi, E., Cao, L., Caplan, A. B., Carding, S. R., Cardoso, S. M., Carew, J. S., Carlin, C. R., Carmignac, V., Carneiro, L. A. M., Carra, S., Caruso, R. A., Casari, G., Casas, C., Castino, R., Cebollero, E., Cecconi, F., Celli, J., Chaachouay, H., Chae, H. J., Chai, C. Y., Chan, D. C., Chan, E. Y., Chang, R. C. C., Che, C. M., Chen, C. C., Chen, G. C., Chen, G. Q., Chen, M., Chen, Q., Chen, S. S. L., Chen, W., Chen, X., Chen, X., Chen, X., Chen, Y. G., Chen, Y., Chen, Y., Chen, Y. J., Chen, Z., Cheng, A., Cheng, C. H. K., Cheng, Y., Cheong, H., Cheong, J. H., Cherry, S., Chess-Williams, R., Cheung, Z. H., Chevet, E., Chiang, H. L., Chiarelli, R., Chiba, T., Chin, L. S., Chiou, S. H., Chisari, F. V., Cho, C. H., Cho, D. H., Choi, A. M. K., Choi, D., Choi, K. S., Choi, M. E., Chouaib, S., Choubey, D., Choubey, V., Chu, C. T., Chuang, T. H., Chueh, S. H., Chun, T., Chwae, Y. J., Chye, M. L., Ciarcia, R., Ciriolo, M. R., Clague, M. J., Clark, R. S. B., Clarke, P. G. H., Clarke, R., Codogno, P., Coller, H. A., Colombo, M. I., Comincini, S., Condello, M., Condorelli, F., Cookson, M. R., Coombs, G. H., Coppens, I., Corbalan, R., Cossart, P., Costelli, P., Costes, S., Coto-Montes, A., Couve, E., Coxon, F. P., Cregg, J. M., Crespo, J. L., Cronjé, M. J., Cuervo, A. M., Cullen, J. J., Czaja, M. J., D'Amelio, M., Darfeuille-Michaud, A., Davids, L. M., Davies, F. E., De Felici, M., De Groot, J. F., De Haan, C. A. M., De Martino, L., De Milito, A., De Tata, V., Debnath, J., Degterev, A., Dehay, B., Delbridge, L. M. D., Demarchi, F., Deng, Y. Z., Dengjel, J., Dent, P., Denton, D., Deretic, V., Desai, S. D., Devenish, R. J., Di Gioacchino, M., Di Paolo, G., Di Pietro, C., Díaz-Araya, G., Díaz-Laviada, I., Diaz-Meco, M. T., Diaz-Nido, J., Dikic, I., Dinesh-Kumar, S. P., Ding, W. X., Distelhorst, C. W., Diwan, A., Djavaheri-Mergny, M., Dokudovskaya, S., Dong, Z., Dorsey, F. C., Dosenko, V., Dowling, J. J., Doxsey, S., Dreux, M., Drew, M. E., Duan, Q., Duchosal, M. A., Duff, K., Dugail, I., Durbeej, M., Duszenko, M., Edelstein, C. L., Edinger, A. L., Egea, G., Eichinger, L., Eissa, N. T., Ekmekcioglu, S., El-Deiry, W. S., Elazar, Z., Elgendy, M., Ellerby, L. M., Er Eng, K., Engelbrecht, A. M., Engelender, S., Erenpreisa, J., Escalante, R., Esclatine, A., Eskelinen, E. L., Espert, L., Espina, V., Fan, H., Fan, J., Fan, Q. W., Fan, Z., Fang, S., Fang, Y., Fanto, M., Fanzani, A., Farkas, T., Farré, J. C., Faure, M., Fechheimer, M., Feng, C. G., Feng, J., Feng, Q., Feng, Y., Fésüs, L., Feuer, R., Figueiredo-Pereira, M. E., Fimia, G. M., Fingar, D. C., Finkbeiner, S., Finkel, T., Finley, K. D., Fiorito, F., Fisher, E. A., Fisher, P. B., Flajolet, M., Florez-McClure, M. L., Florio, S., Fon, E. A., Fornai, F., Fortunato, F., Fotedar, R., Fowler, D. H., Fox, H. S., Franco, R., Frankel, L. B., Fransen, M., Fuentes, J. M., Fueyo, J., Fujii, J., Fujisaki, K., Fujita, E., Fukuda, M., Furukawa, R. H., Gaestel, M., Gailly, P., Gajewska, M., Galliot, B., Galy, V., Ganesh, S., Ganetzky, B., Ganley, I. G., Gao, F. B., Gao, G. F., Gao, J., Garcia, L., Garcia-Manero, G., Garcia-Marcos, M., Garmyn, M., Gartel, A. L., Gatti, E., Gautel, M., Gawriluk, T. R., Gegg, M. E., Geng, J., Germain, M., Gestwicki, J. E., Gewirtz, D. A., Ghavami, S., Ghosh, P., Giammarioli, A. M., Giatromanolaki, A. N., Gibson, S. B., Gilkerson, R. W., Ginger, M. L., Ginsberg, H. N., Golab, J., Goligorsky, M. S., Golstein, P., Gomez-Manzano, C., Goncu, E., Gongora, C., Gonzalez, C. D., Gonzalez, R., González-Estévez, C., González-Polo, R. A., Gonzalez-Rey, E., Gorbunov, N. V., Gorski, S., Goruppi, S., Gottlieb, R. A., Gozuacik, D., Granato, G. E., Grant, G. D., Green, K. N., Gregorc, A., Gros, F., Grose, C., Grunt, T. W., Gual, P., Guan, J. L., Guan, K. L., Guichard, S. M., Gukovskaya, A. S., Gukovsky, I., Gunst, J., Gustafsson, A. B., Halayko, A. J., Hale, A. N., Halonen, S. K., Hamasaki, M., Han, F., Han, T., Hancock, M. K., Hansen, M., Harada, H., Harada, M., Hardt, S. E., Harper, J. W., Harris, A. L., Harris, J., Harris, S. D., Hashimoto, M., Haspel, J. A., Hayashi, S. I., Hazelhurst, L. A., He, C., He, Y. W., Hébert, M. J., Heidenreich, K. A., Helfrich, M. H., Helgason, G. V., Henske, E. P., Herman, B., Herman, P. K., Hetz, C., Hilfiker, S., Hill, J. A., Hocking, L. J., Hofman, P., Hofmann, T. G., Höhfeld, J., Holyoake, T. L., Hong, M. H., Hood, D. A., Hotamisligil, G. S., Houwerzijl, E. J., Høyer-Hansen, M., Hu, B., Hu, C. A. A., Hu, H. M., Hua, Y., Huang, C., Huang, J., Huang, S., Huang, W. P., Huber, T. B., Huh, W. K., Hung, T. H., Hupp, T. R., Hur, G. M., Hurley, J. B., Hussain, S. N. A., Hussey, P. J., Hwang, J. J., Hwang, S., Ichihara, A., Ilkhanizadeh, S., Inoki, K., Into, T., Iovane, V., Iovanna, J. L., Ip, N. Y., Isaka, Y., Ishida, H., Isidoro, C., Isobe, K. I., Iwasaki, A., Izquierdo, M., Izumi, Y., Jaakkola, P. M., Jäättelä, M., Jackson, G. R., Jackson, W. T., Janji, B., Jendrach, M., Jeon, J. H., Jeung, E. B., Jiang, H., Jiang, H., Jiang, J. X., Jiang, M., Jiang, Q., Jiang, X., Jiménez, A., Jin, M., Jin, S., Joe, C. O., Johansen, T., Johnson, D. E., Johnson, G. V. W., Jones, N. L., Joseph, B., Joseph, S. K., Joubert, A. M., Juhász, G., Juillerat-Jeanneret, L., Jung, C. H., Jung, Y. K., Kaarniranta, K., Kaasik, A., Kabuta, T., Kadowaki, M., Kagedal, K., Kamada, Y., Kaminskyy, V. O., Kampinga, H. H., Kanamori, H., Kang, C., Kang, K. B., Il Kang, K., Kang, R., Kang, Y. A., Kanki, T., Kanneganti, T. D., Kanno, H., Kanthasamy, A. G., Kanthasamy, A., Karantza, V., Kaushal, G. P., Kaushik, S., Kawazoe, Y., Ke, P. Y., Kehrl, J. H., Kelekar, A., Kerkhoff, C., Kessel, D. H., Khalil, H., Kiel, J. A. K. W., Kiger, A. A., Kihara, A., Kim, D. R., Kim, D. H., Kim, D. H., Kim, E. K., Kim, H. R., Kim, J. S., Kim, J. H., Kim, J. C., Kim, J. K., Kim, P. K., Kim, S. W., Kim, Y. S., Kim, Y., Kimchi, A., Kimmelman, A. C., King, J. S., Kinsella, T. J., Kirkin, V., Kirshenbaum, L. A., Kitamoto, K., Kitazato, K., Klein, L., Klimecki, W. T., Klucken, J., Knecht, E., Ko, B. C. B., Koch, J. C., Koga, H., Koh, J. Y., Koh, Y. H., Koike, M., Komatsu, M., Kominami, E., Kong, H. J., Kong, W. J., Korolchuk, V. I., Kotake, Y., Koukourakis, M. I., Kouri Flores, J. B., Kovács, A. L., Kraft, C., Krainc, D., Krämer, H., Kretz-Remy, C., Krichevsky, A. M., Kroemer, G., Krüger, R., Krut, O., Ktistakis, N. T., Kuan, C. Y., Kucharczyk, R., Kumar, A., Kumar, R., Kumar, S., Kundu, M., Kung, H. J., Kurz, T., Kwon, H. J., La Spada, A. R., Lafont, F., Lamark, T., Landry, J., Lane, J. D., Lapaquette, P., Laporte, J. F., László, L., Lavandero, S., Lavoie, J. N., Layfield, R., Lazo, P. A., Le, W., Le Cam, L., Ledbetter, D. J., Lee, A. J. X., Lee, B. W., Lee, G. M., Lee, J., Lee, J. H., Lee, M., Lee, M. S., Lee, S. H., Leeuwenburgh, C., Legembre, P., Legouis, R., Lehmann, M., Lei, H. Y., Lei, Q. Y., Leib, D. A., Leiro, J., Lemasters, J. J., Lemoine, A., Lesniak, M. S., Lev, D., Levenson, V. V., Levine, B., Levy, E., Li, F., Li, J. L., Li, L., Li, S., Li, W., Li, X. J., Li, Y. B., Li, Y. P., Liang, C., Liang, Q., Liao, Y. F., Liberski, P. P., Lieberman, A., Lim, H. J., Lim, K. L., Lim, K., Lin, C. F., Lin, F. C., Lin, J., Lin, J. D., Lin, K., Lin, W. W., Lin, W. C., Lin, Y. L., Linden, R., Lingor, P., Lippincott-Schwartz, J., Lisanti, M. P., Liton, P. B., Liu, B., Liu, C. F., Liu, K., Liu, L., Liu, Q. A., Liu, W., Liu, Y. C., Liu, Y., Lockshin, R. A., Lok, C. N., Lonial, S., Loos, B., Lopez-Berestein, G., López-Otín, C., Lossi, L., Lotze, M. T., Lõw, P., Lu, B., Lu, B., Lu, B., Lu, Z., Luciano, F., Lukacs, N. W., Lund, A. H., Lynch-Day, M. A., Ma, Y., Macian, F., MacKeigan, J. P., Macleod, K. F., Madeo, F., Maiuri, L., Maiuri, M. C., Malagoli, D., Malicdan, M. C. V., Malorni, W., Man, N., Mandelkow, E. M., Manon, S., Manov, I., Mao, K., Mao, X., Mao, Z., Marambaud, P., Marazziti, D., Marcel, Y. L., Marchbank, K., Marchetti, P., Marciniak, S. J., Marcondes, M., Mardi, M., Marfe, G., Mariño, G., Markaki, M., Marten, M. R., Martin, S. J., Martinand-Mari, C., Martinet, W., Martinez-Vicente, M., Masini, M., Matarrese, P., Matsuo, S., Matteoni, R., Mayer, A., Mazure, N. M., McConkey, D. J., McConnell, M. J., McDermott, C., McDonald, C., McInerney, G. M., McKenna, S. L., McLaughlin, B., McLean, P. J., McMaster, C. R., McQuibban, G. A., Meijer, A. J., Meisler, M. H., Meléndez, A., Melia, T. J., Melino, G., Mena, M. A., Menendez, J. A., Menna-Barreto, R. F. S., Menon, M. B., Menzies, F. M., Mercer, C. A., Merighi, A., Merry, D. E., Meschini, S., Meyer, C. G., Meyer, T. F., Miao, C. Y., Miao, J. Y., Michels, P. A. M., Michiels, C., Mijaljica, D., Milojkovic, A., Minucci, S., Miracco, C., Miranti, C. K., Mitroulis, I., Miyazawa, K., Mizushima, N., Mograbi, B., Mohseni, S., Molero, X., Mollereau, B., Mollinedo, F., Momoi, T., Monastyrska, I., Monick, M. M., Monteiro, M. J., Moore, M. N., Mora, R., Moreau, K., Moreira, P. I., Moriyasu, Y., Moscat, J., Mostowy, S., Mottram, J. C., Motyl, T., Moussa, C. E. H., Müller, S., Muller, S., Münger, K., Münz, C., Murphy, L. O., Murphy, M. E., Musarò, A., Mysorekar, I., Nagata, E., Nagata, K., Nahimana, A., Nair, U., Nakagawa, T., Nakahira, K., Nakano, H., Nakatogawa, H., Nanjundan, M., Naqvi, N. I., Narendra, D. P., Narita, M., Navarro, M., Nawrocki, S. T., Nazarko, T. Y., Nemchenko, A., Netea, M. G., Neufeld, T. P., Ney, P. A., Nezis, I. P., Nguyen, H. P., Nie, D., Nishino, I., Nislow, C., Nixon, R. A., Noda, T., Noegel, A. A., Nogalska, A., Noguchi, S., Notterpek, L., Novak, I., Nozaki, T., Nukina, N., Nürnberger, T., Nyfeler, B., Obara, K., Oberley, T. D., Oddo, S., Ogawa, M., Ohashi, T., Okamoto, K., Oleinick, N. L., Oliver, F. J., Olsen, L. J., Olsson, S., Opota, O., Osborne, T. F., Ostrander, G. K., Otsu, K., Ou, J. H. J., Ouimet, M., Overholtzer, M., Ozpolat, B., Paganetti, P., Pagnini, U., Pallet, N., Palmer, G. E., Palumbo, C., Pan, T., Panaretakis, T., Pandey, U. B., Papackova, Z., Papassideri, I., Paris, I., Park, J., Park, O. K., Parys, J. B., Parzych, K. R., Patschan, S., Patterson, C., Pattingre, S., Pawelek, J. M., Peng, J., Perlmutter, D. H., Perrotta, I., Perry, G., Pervaiz, S., Peter, M., Peters, G. J., Petersen, M., Petrovski, G., Phang, J. M., Piacentini, M., Pierre, P., Pierrefite-Carle, V., Pierron, G., Pinkas-Kramarski, R., Piras, A., Piri, N., Platanias, L. C., Pöggeler, S., Poirot, M., Poletti, A., Poüs, C., Pozuelo-Rubio, M., Prætorius-Ibba, M., Prasad, A., Prescott, M., Priault, M., Produit-Zengaffinen, N., Progulske-Fox, A., Proikas-Cezanne, T., Przedborski, S., Przyklenk, K., Puertollano, R., Puyal, J., Qian, S. B., Qin, L., Qin, Z. H., Quaggin, S. E., Raben, N., Rabinowich, H., Rabkin, S. W., Rahman, I., Rami, A., Ramm, G., Randall, G., Randow, F., Rao, V. A., Rathmell, J. C., Ravikumar, B., Ray, S. K., Reed, B. H., Reed, J. C., Reggiori, F., Régnier-Vigouroux, A., Reichert, A. S., Reiners, J. J., Reiter, R. J., Ren, J., Revuelta, J. L., Rhodes, C. J., Ritis, K., Rizzo, E., Robbins, J., Roberge, M., Roca, H., Roccheri, M. C., Rocchi, S., Rodemann, H. P., De Córdoba, S. R., Rohrer, B., Roninson, I. B., Rosen, K., Rost-Roszkowska, M. M., Rouis, M., Rouschop, K. M. A., Rovetta, F., Rubin, B. P., Rubinsztein, D. C., Ruckdeschel, K., Rucker, E. B., Rudich, A., Rudolf, E., Ruiz-Opazo, N., Russo, R., Rusten, T. E., Ryan, K. M., Ryter, S. W., Sabatini, D. M., Sadoshima, J., Saha, T., Saitoh, T., Sakagami, H., Sakai, Y., Salekdeh, G. H., Salomoni, P., Salvaterra, P. M., Salvesen, G., Salvioli, R., Sanchez, A. M. J., Sánchez-Alcázar, J. A., Sánchez-Prieto, R., Sandri, M., Sankar, U., Sansanwal, P., Santambrogio, L., Saran, S., Sarkar, S., Sarwal, M., Sasakawa, C., Sasnauskiene, A., Sass, M., Sato, K., Sato, M., Schapira, A. H. V., Scharl, M., Schätzl, H. M., Scheper, W., Schiaffino, S., Schneider, C., Schneider, M. E., Schneider-Stock, R., Schoenlein, P. V., Schorderet, D. F., Schüller, C., Schwartz, G. K., Scorrano, L., Sealy, L., Seglen, P. O., Segura-Aguilar, J., Seiliez, I., Seleverstov, O., Sell, C., Seo, J. B., Separovic, D., Setaluri, V., Setoguchi, T., Settembre, C., Shacka, J. J., Shanmugam, M., Shapiro, I. M., Shaulian, E., Shaw, R. J., Shelhamer, J. H., Shen, H. M., Shen, W. C., Sheng, Z. H., Shi, Y., Shibuya, K., Shidoji, Y., Shieh, J. J., Shih, C. M., Shimada, Y., Shimizu, S., Shintani, T., Shirihai, O. S., Shore, G. C., Sibirny, A. A., Sidhu, S. B., Sikorska, B., Silva-Zacarin, E. C. M., Simmons, A., Simon, A. K., Simon, H. U., Simone, C., Simonsen, A., Sinclair, D. A., Singh, R., Sinha, D., Sinicrope, F. A., Sirko, A., Siu, P. M., Sivridis, E., Skop, V., Skulachev, V. P., Slack, R. S., Smaili, S. S., Smith, D. R., Soengas, M. S., Soldati, T., Song, X., Sood, A. K., Soong, T. W., Sotgia, F., Spector, S. A., Spies, C. D., Springer, W., Srinivasula, S. M., Stefanis, L., Steffan, J. S., Stendel, R., Stenmark, H., Stephanou, A., Stern, S. T., Sternberg, C., Stork, B., Strålfors, P., Subauste, C. S., Sui, X., Sulzer, D., Sun, J., Sun, S. Y., Sun, Z. J., Sung, J. J. Y., Suzuki, K., Suzuki, T., Swanson, M. S., Swanton, C., Sweeney, S. T., Sy, L. K., Szabadkai, G., Tabas, I., Taegtmeyer, H., Tafani, M., Takács-Vellai, K., Takano, Y., Takegawa, K., Takemura, G., Takeshita, F., Talbot, N. J., Tan, K. S. W., Tanaka, K., Tanaka, K., Tang, D., Tang, D., Tanida, I., Tannous, B. A., Tavernarakis, N., Taylor, G. S., Taylor, G. A., Taylor, J. P., Terada, A. S., Terman, A., Tettamanti, G., Thevissen, K., Thompson, C. B., Thorburn, A., Thumm, M., Tian, F., Tian, Y., Tocchini-Valentini, G., Tolkovsky, A. M., Tomino, Y., Tönges, L., Tooze, S. A., Tournier, C., Tower, J., Towns, R., Trajkovic, V., Travassos, L. H., Tsai, T. F., Tschan, M. P., Tsubata, T., Tsung, A., Turk, B., Turner, L. S., Tyagi, S. C., Uchiyama, Y., Ueno, T., Umekawa, M., Umemiya-Shirafuji, R., Unni, V. K., Vaccaro, M. I., Valente, E. M., Van Den Berghe, G., Van Der Klei, I. J., Van Doorn, W. G., Van Dyk, L. F., Van Egmond, M., Van Grunsven, L. A., Vandenabeele, P., Vandenberghe, W. P., Vanhorebeek, I., Vaquero, E. C., Velasco, G., Vellai, T., Vicencio, J. M., Vierstra, R. D., Vila, M., Vindis, C., Viola, G., Viscomi, M. T., Voitsekhovskaja, O. V., Von Haefen, C., Votruba, M., Wada, K., Wade-Martins, R., Walker, C. L., Walsh, C. M., Walter, J., Wan, X. B., Wang, A., Wang, C., Wang, D., Wang, F., Wang, F., Wang, G., Wang, H., Wang, H. G., Wang, H. D., Wang, J., Wang, K., Wang, M., Wang, R. C., Wang, X., Wang, X., Wang, Y. J., Wang, Y., Wang, Z., Wang, Z. C., Wang, Z., Wansink, D. G., Ward, D. M., Watada, H., Waters, S. L., Webster, P., Wei, L., Weihl, C. C., Weiss, W. A., Welford, S. M., Wen, L. P., Whitehouse, C. A., Whitton, J. L., Whitworth, A. J., Wileman, T., Wiley, J. W., Wilkinson, S., Willbold, D., Williams, R. L., Williamson, P. R., Wouters, B. G., Wu, C., Wu, D. C., Wu, W. K. K., Wyttenbach, A., Xavier, R. J., Xi, Z., Xia, P., Xiao, G., Xie, Z., Xie, Z., Xu, D. Z., Xu, J., Xu, L., Xu, X., Yamamoto, A., Yamamoto, A., Yamashina, S., Yamashita, M., Yan, X., Yanagida, M., Yang, D. S., Yang, E., Yang, J. M., Yang, S. Y., Yang, W., Yang, W. Y., Yang, Z., Yao, M. C., Yao, T. P., Yeganeh, B., Yen, W. L., Yin, J. J., Yin, X. M., Yoo, O. J., Yoon, G., Yoon, S. Y., Yorimitsu, T., Yoshikawa, Y., Yoshimori, T., Yoshimoto, K., You, H. J., Youle, R. J., Younes, A., Yu, L., Yu, L., Yu, S. W., Yu, W. H., Yuan, Z. M., Yue, Z., Yun, C. H., Yuzaki, M., Zabirnyk, O., Silva-Zacarin, E., David Zacks, E., Zacksenhaus, L., Zaffaroni, N., Zakeri, Z., Zeh, H. J., Zeitlin, S. O., Zhang, H., Zhang, H. L., Zhang, J., Zhang, J. P., Zhang, L., Zhang, L., Zhang, M. Y., Zhang, X. D., Zhao, M., Zhao, Y. F., Zhao, Y., Zhao, Z. J., Zheng, X., Zhivotovsky, B., Zhong, Q., Zhou, C. Z., Zhu, C., Zhu, W. G., Zhu, X. F., Zhu, X., Zhu, Y., Zoladek, T., Zong, W. X., Zorzano, A., Zschocke, J. & Zuckerbraun, B., Apr 2012, In : Autophagy. 8, 4, p. 445-544 100 p.

Research output: Contribution to journalArticle

Autophagy
Guidelines
Lysosomes
Eukaryota
Research Personnel
2011
1 Citation (Scopus)

Aberrant transcription and post-transcriptional processing of hepatitis C virus non-structural genes in transgenic mice

Desai, M. M., Tumurbataar, B., Zhang, Y., Chan, L. N. L., Sun, J. & Chan, T. S., Dec 2011, In : Transgenic Research. 20, 6, p. 1273-1284 12 p.

Research output: Contribution to journalArticle

Hepatitis C virus
Hepacivirus
Transgenic Mice
transcription (genetics)
genetically modified organisms
26 Citations (Scopus)

Differential, type i interferon-mediated autophagic trafficking of hepatitis C virus proteins in mouse liver

Desai, M. M., Gong, B., Chan, T., Davey, R. A., Soong, L., Kolokoltsov, A. A. & Sun, J., Aug 2011, In : Gastroenterology. 141, 2

Research output: Contribution to journalArticle

Hepacivirus
Interferons
Interferon-beta
Antiviral Agents
Mitochondria
12 Citations (Scopus)

IFNα/β and autophagy: Tug-of-war between HCV and the host

Sun, J., Desai, M. M., Soong, L. & Ou, J. H. J., Nov 2011, In : Autophagy. 7, 11, p. 1394-1396 3 p.

Research output: Contribution to journalArticle

Autophagy
Hepacivirus
Antiviral Agents
Viral Nonstructural Proteins
Proteins
10 Citations (Scopus)

Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice

Yan, J., Jie, Z., Hou, L., Wanderley, J. L., Soong, L., Gupta, S., Qiu, S., Chan, T. & Sun, J., May 2011, In : Hepatology. 53, 5, p. 1455-1467 13 p.

Research output: Contribution to journalArticle

Adenoviridae
Hepatitis
Liver
Major Histocompatibility Complex
Transgenic Mice
2010
13 Citations (Scopus)

T-cell receptor complex is essential for Fas signal transduction

Akimzhanov, A. M., Wang, X., Sun, J. & Boehning, D., Aug 24 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 34, p. 15105-15110 6 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
CD95 Antigens
Signal Transduction
T-Lymphocytes
Death Domain Receptors
57 Citations (Scopus)

Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites

Xin, L., Vargas-Inchaustegui, D. A., Raimer, S., Kelly, B., Hu, J., Zhu, L., Sun, J. & Soong, L., Jun 15 2010, In : Journal of Immunology. 184, 12, p. 7047-7056 10 p.

Research output: Contribution to journalArticle

Leishmania
Innate Immunity
Parasites
Neutrophils
Neutrophil Infiltration
2007
13 Citations (Scopus)

Cre-estrogen receptor-mediated hepatitis C virus structural protein expression in mice

Tumurbaatar, B., Sun, Y., Chan, T. & Sun, J., Dec 2007, In : Journal of Virological Methods. 146, 1-2, p. 5-13 9 p.

Research output: Contribution to journalArticle

Viral Structural Proteins
Hepacivirus
Estrogen Receptors
Apoptosis
Liver
2005
94 Citations (Scopus)

CD4+CD25+ regulatory T cells restrain pathogenic responses during Leishmania amazonensis infection

Ji, J., Masterson, J., Sun, J. & Soong, L., Jun 1 2005, In : Journal of Immunology. 174, 11, p. 7147-7153 7 p.

Research output: Contribution to journalArticle

Leishmania
Regulatory T-Lymphocytes
Infection
T-Lymphocytes
Cutaneous Leishmaniasis
298 Citations (Scopus)

Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production

Korenaga, M., Wang, T., Li, Y., Showalter, L. A., Chan, T., Sun, J. & Weinman, S. A., Nov 11 2005, In : Journal of Biological Chemistry. 280, 45, p. 37481-37488 8 p.

Research output: Contribution to journalArticle

Mitochondria
Electron Transport
Reactive Oxygen Species
Liver Mitochondrion
Glutathione
12 Citations (Scopus)

Parenchymal expression of CD86/B7.2 contributes to hepatitis C virus-related liver injury

Sun, J., Tumurbaatar, B., Jia, J., Diao, H., Bodola, F., Lemon, S. M., Tang, W., Bowen, D. G., McCaughan, G. W., Bertolino, P. & Chan, T. S., Aug 2005, In : Journal of Virology. 79, 16, p. 10730-10739 10 p.

Research output: Contribution to journalArticle

Hepatitis C virus
Hepacivirus
liver
Liver
Wounds and Injuries
2004
82 Citations (Scopus)

Sand Fly Saliva Enhances Leishmania amazonensis Infection by Modulating Interleukin-10 Production

Norsworthy, N. B., Sun, J., Elnaiem, D., Lanzaro, G. & Soong, L., Mar 2004, In : Infection and Immunity. 72, 3, p. 1240-1247 8 p.

Research output: Contribution to journalArticle

Psychodidae
Leishmania
Salivary Glands
Saliva
Interleukin-10
17 Citations (Scopus)

The immunologic basis for hepatitis C infection

Sun, J., Li, K., Shata, M. T. & Chan, T. S., Nov 2004, In : Current Opinion in Gastroenterology. 20, 6, p. 598-602 5 p.

Research output: Contribution to journalArticle

Hepatitis C
Hepacivirus
Interferons
Infection
Virus Diseases
2003
11 Citations (Scopus)

Cell cycle block in anergic T cells during tolerance induction

Sun, J., Stalls, M. A., Thompson, K. L. & Fisher Van Houten, N., Sep 2003, In : Cellular Immunology. 225, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Cell Cycle
T-Lymphocytes
Antigens
Bystander Effect
CD4 Antigens
125 Citations (Scopus)

Impaired expression of inflammatory cytokines and chemokines at early stages of infection with Leishmania amazonensis

Ji, J., Sun, J. & Soong, L., Aug 1 2003, In : Infection and Immunity. 71, 8, p. 4278-4288 11 p.

Research output: Contribution to journalArticle

Leishmania
Chemokines
Leishmania major
Cytokines
Macrophage Inflammatory Proteins
2002
54 Citations (Scopus)

Analysis of T helper cell responses during infection with Leishmania amazonensis

Ji, J., Sun, J., Qi, H. & Soong, L., 2002, In : American Journal of Tropical Medicine and Hygiene. 66, 4, p. 338-345 8 p.

Research output: Contribution to journalArticle

Leishmania
Helper-Inducer T-Lymphocytes
Th2 Cells
T-Cell Antigen Receptor
Interleukin-4
9 Citations (Scopus)

CD40 stimulation in vivo does not inhibit CD4+ T cell tolerance to soluble antigens

Sun, J. & Van Houten, N., Nov 1 2002, In : Immunology Letters. 84, 2, p. 125-132 8 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Antigens
Up-Regulation
Ovalbumin
Immune Tolerance
397 Citations (Scopus)

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus

Lerat, H., Honda, M., Beard, M. R., Loesch, K., Sun, J., Yang, Y., Okuda, M., Gosert, R., Xiao, S., Weinman, S. A. & Lemon, S. M., 2002, In : Gastroenterology. 122, 2, p. 352-365 14 p.

Research output: Contribution to journalArticle

Fatty Liver
Liver Neoplasms
Protein C
Hepacivirus
Transgenic Mice
2001
31 Citations (Scopus)

Hepatitis C virus core and envelope proteins do not suppress the host's ability to clear a hepatic viral infection

Sun, J., Bodola, F., Fan, X., Irshad, H., Soong, L., Lemon, S. M. & Chan, T. S., 2001, In : Journal of Virology. 75, 24, p. 11992-11998 7 p.

Research output: Contribution to journalArticle

Viral Envelope Proteins
Hepatitis C virus
Virus Diseases
liver
Liver
2000
20 Citations (Scopus)

Increased efficiency of folding and peptide loading of mutant MHC class I molecules

Beißbarth, T., Sun, J., Kavathas, P. B. & Ortmann, B., 2000, In : European Journal of Immunology. 30, 4, p. 1203-1213 11 p.

Research output: Contribution to journalArticle

HLA-A2 Antigen
Major Histocompatibility Complex
Peptides
Endoplasmic Reticulum
Alleles
1999
90 Citations (Scopus)

Antigen-specific T cell activation and proliferation during oral tolerance induction

Sun, J., Dirden-Kramer, B., Ito, K., Ernst, P. B. & Van Houten, N., May 15 1999, In : Journal of Immunology. 162, 10, p. 5868-5875 8 p.

Research output: Contribution to journalArticle

Cell Proliferation
T-Lymphocytes
Antigens
Lymph Nodes
Peptides
31 Citations (Scopus)

Orientation of the Ig domains of CD8αβ relative to MHC class I

Devine, L., Sun, J., Barr, M. R. & Kavathas, P. B., Jan 15 1999, In : Journal of Immunology. 162, 2, p. 846-851 6 p.

Research output: Contribution to journalArticle

COS Cells
Membrane Glycoproteins
Cell Adhesion
Immunoglobulin Domains