Joan Nichols, PhD

Associate Dean, Student Affairs-GSBS

  • 1790 Citations
  • 24 h-Index
1984 …2020

Research output per year

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Research Output

  • 1790 Citations
  • 24 h-Index
  • 43 Article
  • 3 Chapter
  • 3 Review article
2019

The role of cell surface expression of influenza virus neuraminidase in induction of human lymphocyte apoptosis

Nichols, J., Niles, J. A., Fleming, E. H. & Roberts, N. J., Aug 1 2019, In : Virology. 534, p. 80-86 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Influenza virus infection of human lymphocytes occurs in the immune cell cluster of the developing antiviral response

Mock, D. J., Frampton, M. W., Nichols, J., Domurat, F. M., Signs, D. J. & Roberts, N. J., Aug 10 2018, In : Viruses. 10, 8, 420.

Research output: Contribution to journalArticle

2 Scopus citations

Production and transplantation of bioengineered lung into a large-animal model

Nichols, J., La Francesca, S., Niles, J. A., Vega, S. P., Argueta, L. B., Frank, L., Christiani, D. C., Pyles, R., Himes, B. E., Zhang, R., Li, S., Sakamoto, J., Rhudy, J., Hendricks, G., Begarani, F., Liu, X., Patrikeev, I., Pal, R., Usheva, E., Vargas, G. & 7 others, Miller, A., Woodson, L., Wacher, A., Grimaldo, M., Weaver, D., Mlcak, R. & Cortiella, J., Aug 1 2018, In : Science Translational Medicine. 10, 452, eaao3926.

Research output: Contribution to journalArticle

23 Scopus citations

Reduced activation and proliferation of human lymphocytes exposed to respiratory syncytial virus compared to cells exposed to influenza virus

Fleming, E. H., Ochoa, E. E., Nichols, J., O'Banion, M. K., Salkind, A. R. & Roberts, N. J., Jan 1 2018, In : Journal of Medical Virology. 90, 1, p. 26-33 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells

Farina, M., Chua, C. Y. X., Ballerini, A., Thekkedath, U., Alexander, J. F., Rhudy, J. R., Torchio, G., Fraga, D., Pathak, R. R., Villanueva, M., Shin, C. S., Niles, J. A., Sesana, R., Demarchi, D., Sikora, A. G., Acharya, G. S., Gaber, A. O., Nichols, J. & Grattoni, A., Sep 1 2018, In : Biomaterials. 177, p. 125-138 14 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

From 2D culture to 3D microchip models: Trachea, bronchi/bronchiole and lung biomimetic models for disease modeling, drug discovery, and personalized medicine

Nichols, J., Vega, S. P., Argueta, L. B., Niles, J. A., Eastaway, A., Smith, M., Brown, D. & Cortiella, J., Nov 30 2016, Regenerative Medicine Technology: On-a-Chip Applications for Disease Modeling, Drug Discovery and Personalized Medicine. CRC Press, p. 141-173 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Giving new life to old lungs: Methods to produce and assess whole human paediatric bioengineered lungs

Nichols, J., La Francesca, S., Vega, S. P., Niles, J. A., Argueta, L. B., Riddle, M., Sakamoto, J., Vargas, G., Pal, R., Woodson, L., Rhudy, J., Lee, D., Seanor, D., Campbell, G., Schnadig, V. & Cortiella, J., 2016, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

22 Scopus citations

Human alveolar macrophages may not be susceptible to direct infection by a human influenza virus

Ettensohn, D. B., Frampton, M. W., Nichols, J. & Roberts, N. J., 2016, In : Journal of Infectious Diseases. 214, 11, p. 1658-1665 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Porcine acellular lung matrix for wound healing and abdominal wall reconstruction: A pilot study

Fernandez-Moure, J. S., Van Eps, J. L., Rhudy, J. R., Cabrera, F. J., Acharya, G. S., Tasciotti, E., Sakamoto, J. & Nichols, J., Feb 13 2016, In : Journal of Tissue Engineering. 7

Research output: Contribution to journalArticle

7 Scopus citations
2014

Effects of the decellularization method on the local stiffness of acellular lungs

Melo, E., Garreta, E., Luque, T., Cortiella, J., Nichols, J., Navajas, D. & Farré, R., May 1 2014, In : Tissue Engineering - Part C: Methods. 20, 5, p. 412-422 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Lung Regeneration. The Bioengineering Approach.

Nichols, J. & Cortiella, J., Jan 1 2014, Regenerative Medicine Applications in Organ Transplantation. Elsevier Inc., p. 691-706 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use

Nichols, J. E., Niles, J. A., Vega, S. P., Argueta, L. B., Eastaway, A. & Cortiella, J., Sep 1 2014, In : Experimental Biology and Medicine. 239, 9, p. 1135-1169 35 p.

Research output: Contribution to journalArticle

43 Scopus citations
2013
35 Scopus citations

Local micromechanical properties of decellularized lung scaffolds measured with atomic force microscopy

Luque, T., Melo, E., Garreta, E., Cortiella, J., Nichols, J., Farré, R. & Navajas, D., Jun 1 2013, In : Acta Biomaterialia. 9, 6, p. 6852-6859 8 p.

Research output: Contribution to journalArticle

39 Scopus citations
51 Scopus citations

Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology

Nichols, J. E., Niles, J. A., Vega, S. P. & Cortiella, J., Dec 20 2013, In : Stem Cell Research and Therapy. 4, SUPPL.1, S7.

Research output: Contribution to journalReview article

21 Scopus citations

Production and assessment of decellularized pig and human lung scaffolds

Nichols, J. E., Niles, J., Riddle, M., Vargas, G., Schilagard, T., Ma, L., Edward, K., La Francesca, S., Sakamoto, J., Vega, S., Ogadegbe, M., Mlcak, R., Deyo, D., Woodson, L., Mcquitty, C., Lick, S., Beckles, D., Melo, E. & Cortiella, J., Sep 1 2013, In : Tissue Engineering - Part A. 19, 17-18, p. 2045-2062 18 p.

Research output: Contribution to journalArticle

99 Scopus citations
2012

Production and utilization of acellular lung scaffolds in tissue engineering

Nichols, J. E., Niles, J. A. & Cortiella, J., Jul 1 2012, In : Journal of Cellular Biochemistry. 113, 7, p. 2185-2192 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
2011

Antiviral activities of ISG20 in positive-strand RNA virus infections

Zhou, Z., Wang, N., Woodson, S. E., Dong, Q., Wang, J., Liang, Y., Rijnbrand, R., Wei, L., Nichols, J. E., Guo, J. T., Holbrook, M. R., Lemon, S. M. & Li, K., Jan 20 2011, In : Virology. 409, 2, p. 175-188 14 p.

Research output: Contribution to journalArticle

57 Scopus citations
2010

Influence of acellular natural lung matrix on murine embryonic stem cell differentiation and tissue formation

Cortiella, J., Niles, J., Cantu, A., Brettler, A., Pham, A., Vargas, G., Winston, S., Wang, J., Walls, S. & Nichols, J. E., Aug 1 2010, In : Tissue Engineering - Part A. 16, 8, p. 2565-2580 16 p.

Research output: Contribution to journalArticle

255 Scopus citations

In vitro human bone marrow analog: Clinical potential

Nichols, J. E., Niles, J., Walls, S. & Cortiella, J., Mar 1 2010, In : Regenerative Medicine. 5, 2, p. 289-298 10 p.

Research output: Contribution to journalReview article

2 Scopus citations
2009

Design and development of tissue engineered lung: Progress and challenges

Nichols, J. E., Niles, J. A. & Cortiella, J., Jan 1 2009, In : Organogenesis. 5, 2, p. 57-61 5 p.

Research output: Contribution to journalReview article

Open Access
35 Scopus citations

Influenza

Nichols, J. E. & LeDuc, J. W., Dec 1 2009, Vaccines for Biodefense and Emerging and Neglected Diseases. Elsevier Inc., p. 497-525 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

In vitro analog of human bone marrow from 3D scaffolds with biomimetic inverted colloidal crystal geometry

Nichols, J. E., Cortiella, J., Lee, J., Niles, J. A., Cuddihy, M., Wang, S., Bielitzki, J., Cantu, A., Mlcak, R., Valdivia, E., Yancy, R., McClure, M. L. & Kotov, N. A., Feb 1 2009, In : Biomaterials. 30, 6, p. 1071-1079 9 p.

Research output: Contribution to journalArticle

85 Scopus citations
2008
61 Scopus citations
2007

Epstein-Barr virus infection of Langerhans cell precursors as a mechanism of oral epithelial entry, persistence, and reactivation

Walling, D. M., Ray, A. J., Nichols, J. E., Flaitz, C. M. & Nichols, C. M., Jul 1 2007, In : Journal of virology. 81, 13, p. 7249-7268 20 p.

Research output: Contribution to journalArticle

37 Scopus citations
2006

Respiratory syncytial virus F envelope protein associates with lipid rafts without a requirement for other virus proteins

Fleming, E. H., Kolokoltsov, A. A., Davey, R. A., Nichols, J. E. & Roberts, N. J., Dec 1 2006, In : Journal of virology. 80, 24, p. 12160-12170 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Tissue-engineered lung: An in vivo and in vitro comparison of polyglycolic acid and pluronic F-127 hydrogel/somatic lung progenitor cell constructs to support tissue growth

Cortiella, J., Nichols, J. E., Kojima, K., Bonassar, L. J., Dargon, P., Roy, A. K., Vacant, M. P., Niles, J. A. & Vacanti, C. A., May 1 2006, In : Tissue Engineering. 12, 5, p. 1213-1225 13 p.

Research output: Contribution to journalArticle

117 Scopus citations
2004

Inverted colloidal crystals as three-dimensional cell scaffolds

Kotov, N. A., Liu, Y., Wang, S., Cumming, C., Eghtedari, M., Vargas, G., Motamedi, M., Nichols, J. & Cortiella, J., Sep 14 2004, In : Langmuir. 20, 19, p. 7887-7892 6 p.

Research output: Contribution to journalArticle

134 Scopus citations
2002

Entrapment of recent thymic emigrants in lymphoid tissues from HIV-infected patients: Association with HIV cellular viral load

Nokta, M. A., Li, X. D., Al-Harthi, L., Nichols, J., Pou, A., Asmuth, D., Landay, A. & Pollard, R. B., Nov 8 2002, In : AIDS. 16, 16, p. 2119-2127 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Nitrogen dioxide exposure: Effects on airway and blood cells

Frampton, M. W., Boscia, J., Roberts, N. J., Azadniv, M., Torres, A., Christopher, C. O. X., Morrow, P. E., Nichols, J., Chalupa, D., Frasier, L. M., Raymond Gibb, F., Speers, D. M., Tsai, Y. & Utell, M. J., Jun 29 2002, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 282, 1 26-1, p. L155-L165

Research output: Contribution to journalArticle

57 Scopus citations
2001

Cellular mechanisms that cause suppressed gamma interferon secretion in endotoxin-tolerant mice

Varma, T. K., Toliver-Kinsky, T. E., Lin, C. Y., Koutrouvelis, A. P., Nichols, J. E. & Sherwood, E. R., Sep 6 2001, In : Infection and immunity. 69, 9, p. 5249-5263 15 p.

Research output: Contribution to journalArticle

45 Scopus citations

Chemokine/CD4 receptor density ratios correlate with HIV replication in lymph node and peripheral blood of HIV-infected individuals

Nokta, M. A., Li, X. D., Nichols, J., Mallen, M., Pou, A., Asmuth, D. & Pollard, R. B., Jan 26 2001, In : AIDS. 15, 2, p. 161-169 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Homeostasis of naive and memory T cell subpopulations in peripheral blood and lymphoid tissues in the context of human immunodeficiency virus infection

Nokta, M. A., Li, X. D., Nichols, J., Pou, A., Asmuth, D. & Pollard, R. B., May 1 2001, In : Journal of Infectious Diseases. 183, 9, p. 1336-1342 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Human lymphocyte apoptosis after exposure to influenza A virus

Nichols, J. E., Niles, J. A. & Roberts, J., Jul 3 2001, In : Journal of virology. 75, 13, p. 5921-5929 9 p.

Research output: Contribution to journalArticle

75 Scopus citations
2000

Multisite comparison of methods for the quantitation of the surface expression of CD38 on CD8+ T lymphocytes

Schmitz, J. L., Czerniewski, M. A., Edinger, M., Plaeger, S., Gelman, R., Wilkening, C. L., Zawadzki, J. A., Wormsley, S. B., Asthana, D., Bauer, Y., Blair, P., Blais, B., Brennan, T., Bucy, P., Campbell, D., Chiu, S., Czerniewski, M., Denny, T., Edinger, M., Franks, P. & 29 others, Gelman, R., Gonzaga, C., Helm, K., Kagan, J., Landay, A., Larson, E., Livnat, D., Luzuriaga, K., McCloskey, T., McFarland, B., Nichols, J., Nickishcer, D., Nokta, M., Pahwa, S., Patki, A., Perfetto, S., Plaeger, S., Quinn, T., Reimann, K., Roberts, N., Rosenblatt, H., Sabath, D., Schmitz, J., Sevin, A., Spina, C., Thomas, J., Valentine, F., Weng, D. & Zhang, B., Jun 15 2000, In : Communications in Clinical Cytometry. 42, 3, p. 174-179 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
1999

Effect of didanosine, stavudine, and hydroxyurea therapy on apoptosis in CD45RA+ and CD45RO+ T lumphocyte subpopulations

Nokta, M., Rossero, R., Nichols, J., Rosenbaum, M. & Pollard, R. B., Feb 10 1999, In : AIDS Research and Human Retroviruses. 15, 3, p. 255-264 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
1998

Effects of nitrogen dioxide exposure on human host defense

Azadniv, M., Utell, M. J., Morrow, P. E., Gibb, F. R., Nichols, J., Roberts, N. J., Speers, D. M., Torres, A., Tsai, Y., Abraham, M. K., Voter, K. Z. & Frampton, M. W., Jun 1 1998, In : Inhalation toxicology. 10, 6, p. 585-601 17 p.

Research output: Contribution to journalArticle

7 Scopus citations

Genetic evaluation of suspected cases of transient HIV-1 infection of infants

Frenkel, L. M., Mullins, J. I., Learn, G. H., Manns-Arcuino, L., Herring, B. L., Kalish, M. L., Steketee, R. W., Thea, D. M., Nichols, J. E., Liu, S. L., Harmache, A., He, X., Muthui, D., Madan, A., Hood, L., Haase, A. T., Zupancic, M., Staskus, K., Wolinsky, S., Krogstad, P. & 9 others, Zhao, J. Q., Chen, I., Koup, R., Ho, D., Korber, B., Apple, R. J., Coombs, R. W., Pahwa, S. & Roberts, N. J., May 15 1998, In : Science. 280, 5366, p. 1073-1077 5 p.

Research output: Contribution to journalArticle

51 Scopus citations
1997

A flow cytometric assay of Fc receptor-mediated phagocytosis

Schürmann, W. H. T., Frampton, M. W., Schürmann, G., Roberts, N. J., Nichols, J. E., Finkelstein, J. N., Oberdörster, G. & Utell, M. J., Jan 1 1997, In : Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung. 10, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Comparative pathogenesis of passaged pichinde virus variants in outsred guinea pigs

Marriott, K., Nichols, J., Roberts, N., Zhang, L. & Aronson, J., Dec 1 1997, In : FASEB Journal. 11, 3, p. A114

Research output: Contribution to journalArticle

1993
9 Scopus citations

Use of FITC-labeled influenza virus and flow cytometry to assess binding and internalization of virus by monocytes-macrophages and lymphocytes

Nichols, J. E., Mock, D. J. & Roberts, N. J., Sep 1 1993, In : Archives of virology. 130, 3-4, p. 441-455 15 p.

Research output: Contribution to journalArticle

24 Scopus citations
1991

Interleukin-1-inhibitor activity induced by respiratory syncytial virus: Abrogation of virus-specific and alternate human lymphocyte proliferative responses

Salkind, A. R., McCarthy, D. O., Nichols, J. E., Domurat, F. M., Walsh, E. E. & Roberts, N. J., Jan 1 1991, In : Journal of Infectious Diseases. 163, 1, p. 71-77 7 p.

Research output: Contribution to journalArticle

40 Scopus citations
Open Access
42 Scopus citations
1989
31 Scopus citations

Regulation of lymphocyte proliferation after influenza virus infection of human mononuclear leukocytes

Roberts, N. J. & Nichols, J. E., Mar 1989, In : Journal of Medical Virology. 27, 3, p. 179-187 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
1984

Magnetic orientation and magnetically sensitive material in a transequatorial migratory bird

Beason, R. C. & Nichols, J. E., Dec 1 1984, In : Nature. 309, 5964, p. 151-153 3 p.

Research output: Contribution to journalArticle

82 Scopus citations