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John Allen, PhD

  • 2651 Citations
  • 19 h-Index
20032021
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  • 4 Similar Profiles
G-Protein-Coupled Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
Receptor, Serotonin, 5-HT2A Medicine & Life Sciences
Arrestin Medicine & Life Sciences
Dopamine D1 Receptors Medicine & Life Sciences
Leydig Cells Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Schizophrenia Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2018 2021

Kinetics of Ligand Binding in Dopamine D1 Receptor Biased Signaling

Allen, J.

National Inst on Drug Abuse

7/15/19 → 6/30/21

Project: Other project

Small Molecule Discovery and Target Validation for Striatal Human Orphan Receptors

Allen, J.

PhRMA Foundation

1/1/18 → 6/30/19

Project: Other project

Research Output 2003 2019

Advances in Dopamine D1 Receptor Ligands for Neurotherapeutics

Felsing, D., Jain, M. & Allen, J., Jul 12 2019, In : Current Topics in Medicinal Chemistry. 19, 16, p. 1365 - 1380 15 p.

Research output: Contribution to journal › Article

Dopamine D1 Receptors
Ligands
Pharmaceutical Chemistry
Structure-Activity Relationship
Reward

Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target

Ye, N., Li, B., Mao, Q., Wold, E. A., Tian, S., Allen, J. & Zhou, J., Jan 16 2019, In : ACS Chemical Neuroscience. 10, 1, p. 190-200 11 p., 10.1021/acschemneuro.8b00572.

Research output: Contribution to journal › Review article

G-Protein-Coupled Receptors
Ligands
Brain
Pharmaceutical Preparations
Pharmacology
1 Citation (Scopus)

Synthesis and pharmacological evaluation of non-catechol G protein biased and unbiased dopamine D1 receptor agonists

Wang, P., Felsing, D., Chen, H., Raval, S., Allen, J. & Zhou, J., May 9 2019, In : ACS Medicinal Chemistry Letters. 10.1021/acsmedchemlett.9b00050, p. 792-799 8 p., 10.1021/acsmedchemlett.9b00050.

Research output: Contribution to journal › Article

Open Access
Dopamine D1 Receptors
Dopamine Agonists
GTP-Binding Proteins
Arrestin
Dopamine
4 Citations (Scopus)

Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction

Felsing, D., Anastasio, N., Miszkiel, J. M., Gilbertson, S. R., Allen, J. & Cunningham, K., Aug 1 2018, In : PLoS One. 13, 8, e0203137.

Research output: Contribution to journal › Article

Receptor, Serotonin, 5-HT2C
Receptor, Serotonin, 5-HT2A
serotonin
Serotonin
receptors

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor

Gray, D., Allen, J., Mente, S., O'Connor, R., Kozak, R. & Ehlers, M., Feb 14 2018, In : Nature Communications. 9, 674, | DOI: 10.1038/s41467-017-02776-7.

Research output: Contribution to journal › Article

Open Access
Arrestin
Dopamine D1 Receptors
dopamine
Catechols
Pharmacokinetics