John Papaconstantinou, PhD

  • 5752 Citations
  • 43 h-Index
1961 …2019
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Genes Chemical Compounds
Liver Medicine & Life Sciences
Messenger RNA Medicine & Life Sciences
Fetal Proteins Medicine & Life Sciences
Lenses Medicine & Life Sciences
Albumins Medicine & Life Sciences
Crystallins Medicine & Life Sciences
p38 Mitogen-Activated Protein Kinases Medicine & Life Sciences

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Research Output 1961 2019

  • 5752 Citations
  • 43 h-Index
  • 159 Article
  • 2 Chapter
  • 1 Review article

Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

Neelakantan, H., Brightwell, C. R., Graber, T., Maroto, R., Wang, H. Y. L., McHardy, S. F., Papaconstantinou, J., Fry, C. & Watowich, S., Jan 1 2019, In : Biochemical Pharmacology.

Research output: Contribution to journalArticle

Nicotinamide N-Methyltransferase
Stem cells
Muscle Cells
Skeletal Muscle
5 Citations (Scopus)

Aged dominant negative p38α MAPK mice are resistant to age-dependent decline in adult-neurogenesis and context discrimination fear conditioning

Cortez, I. D., Bulavin, D. V., Wu, P., McGrath, E. L., Cunningham, K. A., Wakamiya, M., Papaconstantinou, J. & Dineley, K. T., Mar 30 2017, In : Behavioural Brain Research. 322, p. 212-222 11 p.

Research output: Contribution to journalArticle

Dentate Gyrus
Alzheimer Disease
8 Citations (Scopus)

8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging

German, P., Saenz, D., Szaniszlo, P., Aguilera-Aguirre, L., Pan, L., Hegde, M. L., Bacsi, A., Hajas, G., Radak, Z., Ba, X., Mitra, S., Papaconstantinou, J. & Boldogh, I., Apr 14 2016, (Accepted/In press) In : Mechanisms of Ageing and Development.

Research output: Contribution to journalArticle

DNA Repair
Cultured Cells
DNA Glycosylases
27 Citations (Scopus)

Amnion-epithelial-cell-derived exosomes demonstrate physiologic state of cell under oxidative stress

Sheller-Miller, S., Papaconstantinou, J., Urrabaz-Garza, R., Richardson, L., Saade, G., Salomon, C. & Menon, R., Jun 1 2016, In : PLoS One. 11, 6, e0157614.

Research output: Contribution to journalArticle

Oxidative stress
10 Citations (Scopus)

Mitochondrial-generated ROS down regulates insulin signaling via activation of the p38MAPK stress response pathway

Al Lahham, R., Deford, J. H. & Papaconstantinou, J., Jan 5 2016, In : Molecular and Cellular Endocrinology. 419, p. 1-11 11 p.

Research output: Contribution to journalArticle

Chemical activation
Insulin Resistance