Photo of Kai-Lieh Huang

Kai-Lieh Huang

  • 435 Citations
  • 7 h-Index

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 435 Citations
  • 7 h-Index
  • 9 Article
  • 1 Letter

The Integrator Complex Attenuates Promoter-Proximal Transcription at Protein-Coding Genes

Elrod, N. D., Henriques, T., Huang, K. L., Tatomer, D. C., Wilusz, J. E., Wagner, E. J. & Adelman, K., Dec 5 2019, In : Molecular cell. 76, 5, p. 738-752.e7

Research output: Contribution to journalArticle

2 Scopus citations

Integrator subunit 4 is a ‘Symplekin-like’ scaffold that associates with INTS9/11 to form the Integrator cleavage module

Albrecht, T. R., Shevtsov, S. P., Wu, Y., Mascibroda, L. G., Peart, N. J., Huang, K-L., Sawyer, I. A., Tong, L., Dundr, M. & Wagner, E., Jan 1 2018, In : Nucleic Acids Research. 46, 8, p. 4241-4255 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Poly (ADP) ribose polymerase inhibition: A potential treatment of malignant peripheral nerve sheath tumor

Kivlin, C. M., Watson, K. L., Al Sannaa, G. A., Belousov, R., Ingram, D. R., Huang, K-L., May, C. D., Bolshakov, S., Landers, S. M., Kalam, A. A., Slopis, J. M., McCutcheon, I. E., Pollock, R. E., Lev, D., Lazar, A. J. & Torres, K. E., Feb 1 2016, In : Cancer Biology and Therapy. 17, 2, p. 129-138 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate

Huang, K-L., Chadee, A. B., Chen, C. Y. A., Zhang, Y. & Shyu, A. B., Mar 2013, In : RNA. 19, 3, p. 295-305 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Dual targeting of mTOR and Aurora-A kinase for the treatment of uterine leiomyosarcoma

Brewer Savannah, K. J., Demicco, E. G., Lusby, K., Ghadimi, M. P. H., Belousov, R., Young, E., Zhang, Y., Huang, K-L., Lazar, A. J., Hunt, K. K., Pollock, R. E., Creighton, C. J., Anderson, M. L. & Lev, D., Sep 1 2012, In : Clinical Cancer Research. 18, 17, p. 4633-4645 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

Expression of 'drugable' tyrosine kinase receptors in malignant peripheral nerve sheath tumour: Potential molecular therapeutic targets for a chemoresistant cancer

Torres, K. E., Liu, J., Young, E., Huang, K-L., Ghadimi, M., Lusby, K., Lazar, A. J. & Lev, D., Jul 2011, In : Histopathology. 59, 1, p. 156-159 4 p.

Research output: Contribution to journalLetter

7 Scopus citations

Vimentin is a novel AKT1 target mediating motility and invasion

Zhu, Q. S., Rosenblatt, K., Huang, K-L., Lahat, G., Brobey, R., Bolshakov, S., Nguyen, T., Ding, Z., Belousov, R., Bill, K., Luo, X., Lazar, A., Dicker, A., Mills, G. B., Hung, M. C. & Lev, D., Jan 27 2011, In : Oncogene. 30, 4, p. 457-470 14 p.

Research output: Contribution to journalArticle

110 Scopus citations

Vimentin is a novel anti-cancer therapeutic target; insights from In Vitro and In Vivo mice xenograft studies

Lahat, G., Zhu, Q. S., Huang, K-L., Wang, S., Bolshakov, S., Liu, J., Torres, K., Langley, R. R., Lazar, A. J., Hung, M. C. & Lev, D., 2010, In : PLoS One. 5, 4, e10105.

Research output: Contribution to journalArticle

146 Scopus citations

Src family kinases mediate betel quid-induced oral cancer cell motility and could be a biomarker for early invasion in oral squamous cell carcinoma

Chen, J. Y. F., Hung, C. C., Huang, K-L., Chen, Y. T., Liu, S. Y., Chiang, W. F., Chen, H. R., Yen, C. Y., Wu, Y. J., Ko, J. Y. & Jou, Y. S., Dec 2008, In : Neoplasia. 10, 12, p. 1393-1401 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Nongenomic androgen activation of phosphatidylinositol 3-kinase/Akt signaling pathway in MC3T3-E1 osteoblasts

Kang, H. Y., Cho, C. L., Huang, K-L., Wang, J. C., Hu, Y. C., Lin, H. K., Chang, C. & Huang, K. E., Jul 2004, In : Journal of Bone and Mineral Research. 19, 7, p. 1181-1190 10 p.

Research output: Contribution to journalArticle

84 Scopus citations