Kota Ramana, PhD, MS

  • 4106 Citations
  • 36 h-Index
19962021

Research output per year

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Research Output

2011

Aldose reductase: New insights for an old enzyme

Ramana, K. V., 2011, In : Biomol Concepts. 2, p. 103-114

Research output: Contribution to journalArticle

88 Scopus citations

Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma

Yadav, U. C. S., Aguilera-Aguirre, L., Boldogh, I., Ramana, K. V. & Srivastava, S. K., Nov 3 2011, In : Respiratory Research. 12, 145.

Research output: Contribution to journalArticle

7 Scopus citations

Aldose reductase deficiency protects from autoimmune- and endotoxin-induced uveitis in mice

Yadav, U. C. S., Shoeb, M., Srivastava, S. K. & Ramana, K. V., Oct 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 11, p. 8076-8085 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Aldose reductase deficiency protects sugar-induced lens opacification in rats

Reddy, A. B. M., Tammali, R., Mishra, R., Srivastava, S., Srivastava, S. K. & Ramana, K. V., May 30 2011, In : Chemico-Biological Interactions. 191, 1-3, p. 346-350 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

Aldose reductase inhibition suppresses airway inflammation

Yadav, U. C. S., Ramana, K. V. & Srivastava, S. K., May 30 2011, In : Chemico-Biological Interactions. 191, 1-3, p. 339-345 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders

Srivastava, S. K., Yadav, U. C. S., Reddy, A. B. M., Saxena, A., Tammali, R., Shoeb, M., Ansari, N. H., Bhatnagar, A., Petrash, M. J., Srivastava, S. & Ramana, K. V., May 30 2011, In : Chemico-Biological Interactions. 191, 1-3, p. 330-338 9 p.

Research output: Contribution to journalArticle

96 Scopus citations

Amelioration of experimental autoimmune uveoretinitis by aldose reductase inhibition in lewis Rats

Yadav, U. C. S., Shoeb, M., Srivastava, S. K. & Ramana, K. V., Oct 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 11, p. 8033-8041 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma

Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In : Current molecular medicine. 11, 7, p. 599-608 10 p.

Research output: Contribution to journalReview article

6 Scopus citations

Emerging role of antioxidants in the protection of uveitis complications

Yadav, U. C. S., Kalariya, N. M. & Ramana, K. V., Feb 1 2011, In : Current Medicinal Chemistry. 18, 6, p. 931-942 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Inhibition of aldose reductase prevents angiogenesis in vitro and in vivo

Tammali, R., Reddy, A. B. M., Srivastava, S. K. & Ramana, K. V., May 1 2011, In : Angiogenesis. 14, 2, p. 209-221 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

Inhibition of aldose reductase prevents colon cancer metastasis

Tammali, R., Reddy, A. B. M., Saxena, A., Rychahou, P. G., Evers, B. M., Qiu, S., Awasthi, S., Ramana, K. V. & Srivastava, S. K., Aug 11 2011, In : Carcinogenesis. 32, 8, p. 1259-1267 9 p.

Research output: Contribution to journalArticle

35 Scopus citations

Inhibition of aldose reductase prevents endotoxin-induced inflammation by regulating the arachidonic acid pathway in murine macrophages

Shoeb, M., Yadav, U. C. S., Srivastava, S. K. & Ramana, K. V., Nov 1 2011, In : Free Radical Biology and Medicine. 51, 9, p. 1686-1696 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Post-translational protein modification by carotenoid cleavage products

Kalariya, N. M., Ramana, K. V., Srivastava, S. K. & van Kuijk, F. J. G. M., Mar 1 2011, In : BioFactors. 37, 2, p. 104-116 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats

Kalariya, N. M., Reddy, A. B. M., Ansari, N. H., VanKuijk, F. J. G. M. & Ramana, K. V., Jul 1 2011, In : Investigative Ophthalmology and Visual Science. 52, 8, p. 5144-5152 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Targeting aldose reductase for the treatment of cancer

Tammali, R., Srivastava, S. K. & Ramana, K. V., Jun 2011, In : Current Cancer Drug Targets. 11, 5, p. 560-571 12 p.

Research output: Contribution to journalReview article

45 Scopus citations
2010

Aldose reductase: A novel therapeutic target for inflammatory pathologies

Ramana, K. V. & Srivastava, S. K., Jan 1 2010, In : International Journal of Biochemistry and Cell Biology. 42, 1, p. 17-20 4 p.

Research output: Contribution to journalShort survey

109 Scopus citations

Aldose reductase inhibition: Emerging drug target for the treatment of cardiovascular complications

Reddy, A. B. M. & Ramana, K. V., Jan 1 2010, In : Recent patents on cardiovascular drug discovery. 5, 1, p. 25-32 8 p.

Research output: Contribution to journalReview article

16 Scopus citations
12 Scopus citations

Aldose Reductase Inhibition Prevents Metaplasia of Airway Epithelial Cells

Yadav, U. C. S., Aguilera-Aguirre, L., Ramana, K. V., Boldogh, I. & Srivastava, S. K., Dec 1 2010, In : PloS one. 5, 12, e14440.

Research output: Contribution to journalArticle

26 Scopus citations

Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle

Tammali, R., Saxena, A., Srivastava, S. K. & Ramana, K. V., May 1 2010, In : Endocrinology. 151, 5, p. 2140-2150 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Editorial: Aldose reductase inhibition for the treatment of asthma

Srivastava, S. K. & Ramana, K. V., Mar 8 2010, In : Expert Review of Clinical Immunology. 6, 1, p. 1-4 4 p.

Research output: Contribution to journalEditorial

4 Scopus citations

Inhibition of aldose reductase attenuates endotoxin signals in human non-pigmented ciliary epithelial cells

Yadav, U. C. S., Srivastava, S. K. & Ramana, K. V., May 1 2010, In : Experimental Eye Research. 90, 5, p. 555-563 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
35 Scopus citations

Measurement and identification of S-glutathiolated proteins.

Hill, B. G., Ramana, K. V., Cai, J., Bhatnagar, A. & Srivastava, S. K., 2010, In : Methods in enzymology. 473, p. 179-197 19 p.

Research output: Contribution to journalReview article

28 Scopus citations

Prevention of endotoxin-induced uveitis in rats by plant sterol guggulsterone

Kalariya, N. M., Shoeb, M., Reddy, A. B. M., Zhang, M., van Kuijk, F. J. G. M. & Ramana, K. V., Oct 1 2010, In : Investigative Ophthalmology and Visual Science. 51, 10, p. 5105-5113 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Protective role of benfotiamine, a fat-soluble vitamin B1 analogue, in lipopolysaccharide-induced cytotoxic signals in murine macrophages

Yadav, U. C. S., Kalariya, N. M., Srivastava, S. K. & Ramana, K. V., May 1 2010, In : Free Radical Biology and Medicine. 48, 10, p. 1423-1434 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Synthesis, quantification, characterization, and signaling properties of glutathionyl conjugates of enals.

Srivastava, S., Ramana, K. V., Bhatnagar, A. & Srivastava, S. K., 2010, In : Methods in enzymology. 474, p. 297-313 17 p.

Research output: Contribution to journalArticle

12 Scopus citations
7 Scopus citations

Understanding the role of aldose reductase in ocular inflammation

Yadav, U. C. S., Srivastava, S. K. & Ramana, K. V., Jan 1 2010, In : Current molecular medicine. 10, 6, p. 540-549 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
2009

Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation

Tammali, R., Reddy, A. B. M., Ramana, K. V., Petrash, M. J. & Srivastava, S. K., May 13 2009, In : Carcinogenesis. 30, 5, p. 799-807 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Aldose reductase inhibition suppresses the expression of Th2 cytokines and airway inflammation in ovalbumin-induced asthma in mice

Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Ramana, K. V., Boldogh, I., Sur, S., Boulares, H. A. & Srivastava, S. K., Oct 1 2009, In : Journal of Immunology. 183, 7, p. 4723-4732 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Aldose reductase regulates high glucose-induced ectodomain shedding of tumor necrosis factor (TNF)-α via protein kinase C-δ and TNF-α converting enzyme in vascular smooth muscle cells

Reddy, A. B. M., Ramana, K. V., Srivastava, S., Bhatnagar, A. & Srivastava, S. K., Jan 1 2009, In : Endocrinology. 150, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Anti-inflammatory effect of aldose reductase inhibition in murine polymicrobial sepsis

Reddy, A. B. M., Srivastava, S. K. & Ramana, K. V., Dec 1 2009, In : Cytokine. 48, 3, p. 170-176 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Cadmium-induced apoptotic death of human retinal pigment epithelial cells is mediated by MAPK pathway

Kalariya, N. M., Wills, N. K., Ramana, K. V., Srivastava, S. K. & van Kuijk, F. J. G. M., Oct 1 2009, In : Experimental Eye Research. 89, 4, p. 494-502 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Focus on Molecules: Nuclear factor-kappaB

Srivastava, S. K. & Ramana, K. V., Jan 5 2009, In : Experimental Eye Research. 88, 1, p. 2-3 2 p.

Research output: Contribution to journalShort survey

53 Scopus citations

Genotoxic effects of carotenoid breakdown products in human retinal pigment epithelial cells

Kalariya, N. M., Ramana, K. V., Srivastava, S. K. & Van Kuijk, F. J. G. M., Nov 9 2009, In : Current Eye Research. 34, 9, p. 737-747 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Inhibition of aldose reductase prevents experimental allergic airway inflammation in mice

Yadav, U. C. S., Ramana, K. V., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A. & Srivastava, S. K., Aug 6 2009, In : PloS one. 4, 8, e6535.

Research output: Contribution to journalArticle

40 Scopus citations

Molecular cloning and oxidative modification of human lens ALDH1A1: Implication in impaired detoxification of lipid aldehydes

Xiao, T., Shoeb, M., Siddiqui, M. S., Zhang, M., Ramana, K. V., Srivastava, S. K., Vasiliou, V. & Ansari, N. H., Dec 1 2009, In : Journal of Toxicology and Environmental Health - Part A: Current Issues. 72, 9, p. 577-584 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Prevention of endotoxin-induced uveitis in rats by benfotiamine, a lipophilic analogue of vitamin B1

Yadav, U. C. S., Subramanyam, S. & Ramana, K. V., Dec 1 2009, In : Investigative Ophthalmology and Visual Science. 50, 5, p. 2276-2282 7 p.

Research output: Contribution to journalArticle

36 Scopus citations

Prevention of posterior capsular opacification through aldose reductase inhibition

Yadav, U. C. S., Ighani-Hosseinabad, F., Van Kuijk, F. J. G. M., Srivastava, S. K. & Ramana, K. V., Feb 1 2009, In : Investigative Ophthalmology and Visual Science. 50, 2, p. 752-759 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
2008

Carotenoid derived aldehydes-induced oxidative stress causes apoptotic cell death in human retinal pigment epithelial cells

Kalariya, N. M., Ramana, K. V., Srivastava, S. K. & van Kuijk, F. J. G. M., Jan 1 2008, In : Experimental Eye Research. 86, 1, p. 70-80 11 p.

Research output: Contribution to journalArticle

58 Scopus citations

Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells

Yadav, U. C. S., Ramana, K. V., Awasthi, Y. C. & Srivastava, S. K., Mar 1 2008, In : Toxicology and Applied Pharmacology. 227, 2, p. 257-264 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

l-Arginine prevents metabolic effects of high glucose in diabetic mice

West, M. B., Ramana, K. V., Kaiserova, K., Srivastava, S. K. & Bhatnagar, A., Jul 23 2008, In : FEBS Letters. 582, 17, p. 2609-2614 6 p.

Research output: Contribution to journalArticle

20 Scopus citations
2007

Aldose reductase inhibition prevents endotoxin-induced uveitis in rats

Yadav, U. C. S., Srivastava, S. K. & Ramana, K. V., Oct 1 2007, In : Investigative Ophthalmology and Visual Science. 48, 10, p. 4634-4642 9 p.

Research output: Contribution to journalArticle

68 Scopus citations

Aldose reductase mediates endotoxin-induced production of nitric oxide and cytotoxicity in murine macrophages

Ramana, K. V., Reddy, A. B. M., Tammali, R. & Srivastava, S. K., Apr 15 2007, In : Free Radical Biology and Medicine. 42, 8, p. 1290-1302 13 p.

Research output: Contribution to journalArticle

45 Scopus citations

Aldose reductase-regulated tumor necrosis factor-α production is essential for high glucose-induced vascular smooth muscle cell growth

Ramana, K. V., Tammali, R., Reddy, A. B. M., Bhatnagar, A. & Srivastava, S. K., Sep 1 2007, In : Endocrinology. 148, 9, p. 4371-4384 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Aldose reductase regulates TNF-α-induced PGE2 production in human colon cancer cells

Tammali, R., Ramana, K. V. & Srivastava, S. K., Jul 18 2007, In : Cancer Letters. 252, 2, p. 299-306 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
2006

Aldose reductase mediates the lipopolysaccharide-induced release of inflammatory mediators in RAW264.7 murine macrophages

Ramana, K. V., Fadl, A. A., Tammali, R., Reddy, A. B. M., Chopra, A. K. & Srivastava, S. K., Nov 3 2006, In : Journal of Biological Chemistry. 281, 44, p. 33019-33029 11 p.

Research output: Contribution to journalArticle

114 Scopus citations

Aldose reductase prevents aldehyde toxicity in cultured human lens epithelial cells

Pladzyk, A., Ramana, K. V., Ansari, N. H. & Srivastava, S. K., Aug 1 2006, In : Experimental Eye Research. 83, 2, p. 408-416 9 p.

Research output: Contribution to journalArticle

17 Scopus citations