Kota Ramana, PhD, MS

  • 3973 Citations
  • 36 h-Index
19962020
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Research Output 1996 2019

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Article
2004
15 Citations (Scopus)

Oxidative stress-induced up-regulation of the chloride channel and Na +/Ca2+ exchanger during cataractogenesis in diabetic rats

Ramana, K., Chandra, D., Wills, N. K., Bhatnagar, A. & Srivastava, S., May 2004, In : Journal of Diabetes and its Complications. 18, 3, p. 177-182 6 p.

Research output: Contribution to journalArticle

Chloride Channels
Oxidative Stress
Up-Regulation
Proteins
Lenses
2003
1 Citation (Scopus)

Aldose reductase and the stress response

Bhatnagar, A., Liu, S. Q., Srivastava, S., Ramana, K. & Srivastava, S., 2003, In : ACS Symposium Series. 865, p. 199-210 12 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Oxidoreductases
2 Citations (Scopus)

Aldose reductase detoxifies lipid aldehydes and their glutathione conjugates

Srivastava, S., Ramana, K., Srivastava, S. & Bhatnagar, A., 2003, In : ACS Symposium Series. 865, p. 37-48 12 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Aldehydes
Glutathione
Lipids
79 Citations (Scopus)
Aldehyde Reductase
Hyperglycemia
Lenses
Tumor Necrosis Factor-alpha
Epithelial Cells
21 Citations (Scopus)

Aldose reductase mediates the mitogenic signals of cytokines

Ramana, K., Chandra, D., Srivastava, S., Bhatnagar, A. & Srivastava, S., Feb 1 2003, In : Chemico-Biological Interactions. 143-144, p. 587-596 10 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Cytokines
Chemical activation
Vascular Smooth Muscle
Smooth Muscle Myocytes

Aldose reductase regulates reactive oxygen species mediated-inflammatory signals

Ramana, K., Chandra, D., Srivastava, S., Bhatnagar, A., Aggarwal, B. B. & Srivastava, S., 2003, In : ACS Symposium Series. 865, p. 213-223 11 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Reactive Oxygen Species
42 Citations (Scopus)

Nitric oxide regulates the polyol pathway of glucose metabolism in vascular smooth muscle cells

Ramana, K., Chandra, D., Srivastava, S., Bhatnagar, A. & Srivastava, S., Mar 1 2003, In : FASEB Journal. 17, 3, p. 417-425 9 p.

Research output: Contribution to journalArticle

aldehyde reductase
Aldehyde Reductase
polyols
Vascular Smooth Muscle
blood vessels
27 Citations (Scopus)

Regulation of aldose reductase and the polyol pathway activity by nitric oxide

Srivastava, S., Ramana, K., Chandra, D., Srivastava, S. & Bhatnagar, A., Feb 1 2003, In : Chemico-Biological Interactions. 143-144, p. 333-340 8 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Nitric Oxide
Nitric Oxide Donors
Sorbitol
Diabetes Complications
2 Citations (Scopus)

Role of aldose reductase in the detoxification of oxidized phospholipids

Srivastava, S., Ramana, K., Srivastava, S. K., D'Souza, S. E. & Bhatnagar, A., 2003, In : ACS Symposium Series. 865, p. 49-64 16 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Detoxification
Phospholipids
Oxidoreductases
15 Citations (Scopus)

Role of aldose reductase in TNF-α-induced apoptosis of vascular endothelial cells

Chandra, D., Ramana, K., Friedrich, B., Srivastava, S., Bhatnagar, A. & Srivastava, S., Feb 1 2003, In : Chemico-Biological Interactions. 143-144, p. 605-612 8 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Endothelial cells
Endothelial Cells
Tumor Necrosis Factor-alpha
Apoptosis
2002
99 Citations (Scopus)

Aldose reductase mediates mitogenic signaling in vascular smooth muscle cells

Ramana, K., Chandra, D., Srivastava, S., Bhatnagar, A., Aggarwal, B. B. & Srivastava, S., Aug 30 2002, In : Journal of Biological Chemistry. 277, 35, p. 32063-32070 8 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
Cells
1 Citation (Scopus)

Estimation of oxygen free radicals and nonenzymatic antioxidants in living-related donor kidney transplantation

Minz, M., Ramana, K., Sakhuja, V. K. & Ganguly, N. K., Sep 2002, In : Transplantation Proceedings. 34, 6, p. 2029 1 p.

Research output: Contribution to journalArticle

Living Donors
Malondialdehyde
Vitamin A
Vitamin E
Kidney Transplantation
38 Citations (Scopus)

Inhibition of fiber cell globulization and hyperglycemia-induced lens opacification by aminopeptidase inhibitor bestatin

Chandra, D., Ramana, K., Wang, L., Christensen, B. N., Bhatnagar, A. & Srivastava, S., 2002, In : Investigative Ophthalmology and Visual Science. 43, 7, p. 2285-2292 8 p.

Research output: Contribution to journalArticle

Aminopeptidases
Hyperglycemia
Lenses
leucylmethionine
Calpain
58 Citations (Scopus)

Nitric oxide prevents aldose reductase activation and sorbitol accumulation during diabetes

Chandra, D., Jackson, E. B., Ramana, K., Kelley, R., Srivastava, S. & Bhatnagar, A., Oct 1 2002, In : Diabetes. 51, 10, p. 3095-3101 7 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Sorbitol
Nitric Oxide
NG-Nitroarginine Methyl Ester
Nitric Oxide Donors
2001
18 Citations (Scopus)

Characterization of the glutathione binding site of aldose reductase

Ramana, K., Dixit, B. L., Srivastava, S., Bhatnagar, A., Balendiran, G. K., Watowich, S., Petrash, J. M. & Srivastava, S., Jan 30 2001, In : Chemico-Biological Interactions. 130-132, p. 537-548 12 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Aldehydes
Glutathione
Binding Sites
Catalytic Domain
8 Citations (Scopus)

Metabolic regulation of aldose reductase activity by nitric oxide donors

Dixit, B. L., Ramana, K., Chandra, D., Jackson, E. B., Srivastava, S., Bhatnagar, A. & Srivastava, S., Jan 30 2001, In : Chemico-Biological Interactions. 130-132, p. 573-581 9 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Penicillamine
Nitric Oxide Donors
Nitrosation
Enzyme activity
32 Citations (Scopus)

Structural and kinetic modifications of aldose reductase by S-nitrosothiols

Srivastava, S., Dixit, B. L., Ramana, K., Chandra, A., Chandra, D., Zacarias, A., Petrash, J. M., Bhatnagar, A. & Srivastava, S., Aug 15 2001, In : Biochemical Journal. 358, 1, p. 111-118 8 p.

Research output: Contribution to journalArticle

S-Nitrosothiols
Aldehyde Reductase
Kinetics
Penicillamine
Nitric Oxide
2000
76 Citations (Scopus)

Kinetic and structural characterization of the glutathione-binding site of aldose reductase

Dixit, B. L., Balendiran, G. K., Watowich, S., Srivastava, S., Ramana, K., Petrash, J. M., Bhatnagar, A. & Srivastava, S., Jul 14 2000, In : Journal of Biological Chemistry. 275, 28, p. 21587-21595 9 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Glutathione
Binding Sites
Kinetics
Catalytic Domain
84 Citations (Scopus)

Selective recognition of glutathiolated aldehydes by aldose reductase

Ramana, K., Dixit, B. L., Srivastava, S., Balendiran, G. K., Srivastava, S. & Bhatnagar, A., Oct 10 2000, In : Biochemistry. 39, 40, p. 12172-12180 9 p.

Research output: Contribution to journalArticle

Aldehyde Reductase
Aldehydes
glutamyl-cysteinyl-alanine
Mutation
Aminobutyrates
1999
2 Citations (Scopus)
Rifampin
Oxidative Stress
Pyrazinamide
Liver
Enzymes
6 Citations (Scopus)
Aminopyrine
Phenobarbital
Macaca mulatta
Isoenzymes
Purification
1998
3 Citations (Scopus)

Differential effects of phenobarbitone on the hepatic and renal glutathione-S-transferases in the rhesus monkey

Ramana, K. & Kohli, K. K., Feb 1998, In : Indian Journal of Pharmacology. 30, 1, p. 34-37 4 p.

Research output: Contribution to journalArticle

Phenobarbital
Glutathione Transferase
Macaca mulatta
Kidney
Ethacrynic Acid
14 Citations (Scopus)

Gene regulation of cytochrome P450 - An overview

Ramana, K. & Kohli, K. K., May 1998, In : Indian Journal of Experimental Biology. 36, 5, p. 437-446 10 p.

Research output: Contribution to journalArticle

Gene expression
Cytochrome P-450 Enzyme System
Transcription Factors
Genes
Eukaryota
NADPH-Ferrihemoprotein Reductase
Mixed Function Oxygenases
Macaca mulatta
Purification
Cytochromes b5
1996
5 Citations (Scopus)

Induction of hepatic cytochrome P450 by phenobarbitone in rhesus monkey (Macaca mulatta)

Ramana, K. & Kohli, K. K., 1996, In : Drug and Chemical Toxicology. 19, 1-2, p. 97-107 11 p.

Research output: Contribution to journalArticle

Phenobarbital
Macaca mulatta
Cytochrome P-450 Enzyme System
Aminopyrine N-Demethylase
Proteins