Research output per year
Research output per year
- 1 - 50 out of 136 results
Search results
-
2023
Characterization of a Novel Thermostable DNA Lyase Used To Prepare DNA for Next-Generation Sequencing
Baljinnyam, T., Conrad, J., Sowers, M. L., Chang-Gu, B., Herring, J., Hackfeld, L. C., Zhang, K. & Sowers, L. C., Feb 20 2023, In: Chemical Research in Toxicology. 36, 2, p. 162-176 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
DNA Base Excision Repair Intermediates Influence Duplex–Quadruplex Equilibrium
Sowers, M. L., Conrad, J., Chang-Gu, B., Cherryhomes, E., Hackfeld, L. C. & Sowers, L. C., Feb 2023, In: Molecules. 28, 3, 970.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Transition Mutations in the hTERT Promoter Are Unrelated to Potential i-motif Formation in the C-Rich Strand
Conrad, J., Sowers, M. L., Yap, D. Y., Cherryhomes, E., Pettitt, B. M., Khanipov, K. & Sowers, L. C., Sep 2023, In: Biomolecules. 13, 9, 1308.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
A combinatorial system to examine the enzymatic repair of multiply damaged DNA substrates
Hsu, C. W., Conrad, J., Sowers, M. L., Baljinnyam, T., Herring, J., Hackfeld, L. C., Hatch, S. S. & Sowers, L. C., Jul 22 2022, In: Nucleic acids research. 50, 13, p. 7406-7419 14 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Chemical and enzymatic modifications of 5-methylcytosine at the intersection of DNA damage, repair, and epigenetic reprogramming
Baljinnyam, T., Sowers, M. L., Hsu, C. W., Conrad, J., Herring, J., Hackfeld, L. C. & Sowers, L. C., Aug 2022, In: PloS one. 17, 8 August, e0273509.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Measurement of deaminated cytosine adducts in DNA using a novel hybrid thymine DNA glycosylase
Hsu, C. W., Sowers, M. L., Baljinnyam, T., Herring, J., Hackfeld, L. C., Tang, H., Zhang, K. & Sowers, L. C., Mar 1 2022, In: Journal of Biological Chemistry. 298, 3, 101638.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2020
Pharmacological approaches to the treatment of COVID-19 patients
Sowers, L., Blanton, L., Weaver, S., Urban, R. & Mouton, C., May 28 2020, In: Journal of Translational Science. 7, p. 1-12Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant
López-García, I., Gerő, D., Szczesny, B., Szoleczky, P., Olah, G., Módis, K., Zhang, K., Gao, J., Wu, P., Sowers, L. C., DeWitt, D., Prough, D. S. & Szabo, C., 2018, In: British Journal of Pharmacology. 175, 2, p. 284-300 17 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
2017
MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain
Lagger, S., Connelly, J. C., Schweikert, G., Webb, S., Selfridge, J., Ramsahoye, B. H., Yu, M., He, C., Sanguinetti, G., Sowers, L. C., Walkinshaw, M. D. & Bird, A., May 2017, In: PLoS genetics. 13, 5, e1006793.Research output: Contribution to journal › Article › peer-review
Open Access94 Scopus citations -
Proteome analysis of hypoxic glioblastoma cells reveals sequential metabolic adaptation of one-carbon metabolic pathways
Zhang, K., Xu, P., Sowers, J. L., Machuca, D. F., Mirfattah, B., Herring, J., Tang, H., Chen, Y., Tian, B., Brasier, A. R. & Sowers, L. C., Nov 2017, In: Molecular and Cellular Proteomics. 16, 11, p. 1906-1921 16 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
2016
In vivo triglyceride synthesis in subcutaneous adipose tissue of humans correlates with plasma HDL parameters
Tuvdendorj, D., Munoz, A. O., Ruiz-Barros, V., Schwarz, J. M., Montalto, G., Chandalia, M., Sowers, L. C., Rizzo, M., Murphy, E. J. & Abate, N., Aug 1 2016, In: Atherosclerosis. 251, p. 147-152 6 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Measurement of Histone Methylation Dynamics by One-Carbon Metabolic Isotope Labeling and High-energy Collisional Dissociation Methylation Signature Ion Detection
Tang, H., Tian, B., Brasier, A. R., Sowers, L. C. & Zhang, K., Aug 17 2016, In: Scientific reports. 6, 31537.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
The Polarization of M2b Monocytes in Cultures of Burn Patient Peripheral CD14+ Cells Treated with a Selected Human CCL1 Antisense Oligodeoxynucleotide
Ito, I., Bhopale, K. K., Nishiguchi, T., Lee, J. O., Herndon, D. N., Suzuki, S., Sowers, L. C., Suzuki, F. & Kobayashi, M., Oct 1 2016, In: Nucleic Acid Therapeutics. 26, 5, p. 269-276 8 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
2015
Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells
McLean, L. S., Watkins, C. N., Campbell, P., Zylstra, D., Rowland, L., Amis, L. H., Scott, L., Babb, C. E., Livingston, W. J., Darwanto, A., Davis, W. L., Senthil, M., Sowers, L. C. & Brantley, E., May 18 2015, In: Chemical Research in Toxicology. 28, 5, p. 855-871 17 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Measurement of Postreplicative DNA Metabolism and Damage in the Rodent Brain
Patel, J. P., Sowers, M. L., Herring, J., Theruvathu, J. A., Emmett, M. R., Hawkins, B. E., Zhang, K., Dewitt, D. S., Prough, D. S. & Sowers, L. C., Dec 21 2015, In: Chemical Research in Toxicology. 28, 12, p. 2352-2363 12 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Quantification of Histone Modifications by Parallel-Reaction Monitoring: A Method Validation
Sowers, J. L., Mirfattah, B., Xu, P., Tang, H., Park, I. Y., Walker, C., Wu, P., Laezza, F., Sowers, L. C. & Zhang, K., Oct 6 2015, In: Analytical Chemistry. 87, 19, p. 10006-10014 9 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2014
Epigenetic alteration by DNA-demethylating treatment restores apoptotic response to glucocorticoids in dexamethasone-resistant human malignant lymphoid cells
Miller, A. L., Geng, C., Golovko, G., Sharma, M., Schwartz, J. R., Yan, J., Sowers, L., Widger, W. R., Fofanov, Y., Vedeckis, W. V. & Thompson, E. B., Apr 23 2014, In: Cancer Cell International. 14, 1, 35.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Multiplexed parallel reaction monitoring targeting histone modifications on the QExactive mass spectrometer
Tang, H., Fang, H., Yin, E., Brasier, A. R., Sowers, L. C. & Zhang, K., Jun 3 2014, In: Analytical Chemistry. 86, 11, p. 5526-5534 9 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
The effect of Pot1 binding on the repair of thymine analogs in a telomeric DNA sequence
Theruvathu, J. A., Darwanto, A., Hsu, C. W. & Sowers, L. C., Aug 18 2014, In: Nucleic acids research. 42, 14, p. 9063-9073 11 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2013
Comparison of the structural and dynamic effects of 5-methylcytosine and 5-chlorocytosine in a CpG dinucleotide sequence
Theruvathu, J. A., Yin, Y. W., Pettitt, B. M. & Sowers, L. C., Nov 26 2013, In: Biochemistry. 52, 47, p. 8590-8598 9 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Enthalpy-entropy compensation in biomolecular halogen bonds measured in DNA junctions
Carter, M., Voth, A. R., Scholfield, M. R., Rummel, B., Sowers, L. C. & Ho, P. S., Jul 23 2013, In: Biochemistry. 52, 29, p. 4891-4903 13 p.Research output: Contribution to journal › Article › peer-review
64 Scopus citations -
2012
Epigenetics of chronic rhinosinusitis and the role of the eosinophil
Seiberling, K. A., Church, C. A., Herring, J. L. & Sowers, L. C., Jan 2012, In: International Forum of Allergy and Rhinology. 2, 1, p. 80-84 5 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Inhaled nitric oxide therapy increases blood nitrite, nitrate, and s-nitrosohemoglobin concentrations in infants with pulmonary hypertension
Ibrahim, Y. I., Ninnis, J. R., Hopper, A. O., Deming, D. D., Zhang, A. X., Herring, J. L., Sowers, L. C., McMahon, T. J., Power, G. G. & Blood, A. B., Feb 2012, In: Journal of Pediatrics. 160, 2, p. 245-251 7 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2011
Inhaled nitrite reverses hemolysis-induced pulmonary vasoconstriction in newborn lambs without blood participation
Blood, A. B., Schroeder, H. J., Terry, M. H., Merrill-Henry, J., Bragg, S. L., Vrancken, K., Liu, T., Herring, J. L., Sowers, L. C., Wilson, S. M. & Power, G. G., Feb 15 2011, In: Circulation. 123, 6, p. 605-612 8 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
Mass spectrometric studies on epigenetic interaction networks in cell differentiation
Xiong, L., Darwanto, A., Sharma, S., Herring, J., Hu, S., Filippova, M., Filippov, V., Wang, Y., Chen, C. S., Duerksen-Hughes, P. J., Sowers, L. C. & Zhang, K., Apr 15 2011, In: Journal of Biological Chemistry. 286, 15, p. 13657-13668 12 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
2010
Impact of base analogues within a CpG dinucleotide on the binding of DNA by the methyl-binding domain of MeCP2 and methylation by DNMT1
Lao, V. V., Darwanto, A. & Sowers, L. C., Nov 30 2010, In: Biochemistry. 49, 47, p. 10228-10236 9 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Polymerase incorporation and miscoding properties of 5-chlorouracil
Kim, C. H., Darwanto, A., Theruvathu, J. A., Herring, J. L. & Sowers, L. C., Apr 19 2010, In: Chemical Research in Toxicology. 23, 4, p. 740-748 9 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Role of tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
Ito, S., Dalessio, A. C., Taranova, O. V., Hong, K., Sowers, L. C. & Zhang, Y., Aug 26 2010, In: Nature. 466, 7310, p. 1129-1133 5 p.Research output: Contribution to journal › Article › peer-review
Open Access2103 Scopus citations -
2009
Base pairing configuration and stability of an oligonucleotide duplex containing a 5-chlorouracil-adenine base pair
Theruvathu, J. A., Kim, C. H., Rogstad, D. K., Neidigh, J. W. & Sowers, L. C., Aug 11 2009, In: Biochemistry. 48, 31, p. 7539-7546 8 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Characterization of DNA glycosylase activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Darwanto, A., Farrel, A., Rogstad, D. K. & Sowers, L. C., Nov 1 2009, In: Analytical Biochemistry. 394, 1, p. 13-23 11 p.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
Chemical decomposition of 5-aza-2′-deoxycytidine (Decitabine): Kinetic analyses and identification of products by NMR, HPLC, and mass spectrometry
Rogstad, D. K., Herring, J. L., Theruvathu, J. A., Burdzy, A., Perry, C. C., Neidigh, J. W. & Sowers, L. C., Jun 15 2009, In: Chemical Research in Toxicology. 22, 6, p. 1194-1204 11 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
Cloning and characterization of Rhodotorula glutinis thymine hydroxylase
Neidigh, J. W., Darwanto, A., Williams, A. A., Wall, N. R. & Sowers, L. C., May 18 2009, In: Chemical Research in Toxicology. 22, 5, p. 885-893 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Efficacy Comparison Between Intraportal and Subcapsular Islet Transplants in a Murine Diabetic Model
Sakata, N., Tan, A., Chan, N., Obenaus, A., Mace, J., Peverini, R., Sowers, L., Chinnock, R. & Hathout, E., Jan 2009, In: Transplantation proceedings. 41, 1, p. 346-349 4 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Enzymatic methylation of DNA in cultured human cells studied by stable isotope incorporation and mass spectrometry
Herring, J. L., Rogstad, D. K. & Sowers, L. C., Jun 15 2009, In: Chemical Research in Toxicology. 22, 6, p. 1060-1068 9 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Impact of sugar pucker on base pair and mispair stability
Williams, A. A., Darwanto, A., Theruvathu, J. A., Burdzy, A., Neidigh, J. W. & Sowers, L. C., Dec 22 2009, In: Biochemistry. 48, 50, p. 11994-12004 11 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Incorporation of 5-chlorocytosine into mammalian DNA results in heritable gene silencing and altered cytosine methylation patterns
Lao, V. V., Herring, J. L., Kim, C. H., Darwanto, A., Soto, U. & Sowers, L. C., 2009, In: Carcinogenesis. 30, 5, p. 886-893 8 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Increased plasma nitric oxide, L-arginine, and arginase-1 in cirrhotic patients with progressive renal dysfunction
Kayali, Z., Herring, J., Baron, P., Franco, E., Ojogho, O., Smith, J., Watkins, G., Smith, D., Lamin, V., Hoang, T., Sharma, R., Mathahs, M., Sowers, L., Brown, K. E. & Schmidt, W. N., Jun 2009, In: Journal of Gastroenterology and Hepatology (Australia). 24, 6, p. 1030-1037 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
In vivo imaging demonstrates a time-line for new vessel formation in islet transplantation
Hathout, E., Chan, N. K., Tan, A., Sakata, N., MacE, J., Pearce, W., Peverini, R., Chinnock, R., Sowers, L. & Obenaus, A., Nov 2009, In: Pediatric Transplantation. 13, 7, p. 892-897 6 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase
Darwanto, A., Theruvathu, J. A., Sowers, J. L., Rogstad, D. K., Pascal, T., Goddard, W. & Sowers, L. C., Jun 5 2009, In: Journal of Biological Chemistry. 284, 23, p. 15835-15846 12 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Monitoring neovascularization of intraportal islet grafts by dynamic contrast enhanced magnetic resonance imaging.
Chan, N., Obenaus, A., Tan, A., Sakata, N., Mace, J., Peverini, R., Chinnock, R., Sowers, L. C. & Hathout, E., 2009, In: Islets. 1, 3, p. 249-255 7 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
MRI assessment of ischemic liver after intraportal islet transplantation
Sakata, N., Hayes, P., Tan, A., Chan, N. K., MacE, J., Peverini, R., Sowers, L., Pearce, W. J., Chinnock, R., Obenaus, A. & Hathout, E., Mar 27 2009, In: Transplantation. 87, 6, p. 825-830 6 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
pH-dependent configurations of a 5-chlorouracil-guanine base pair
Theruvathu, J. A., Kim, C. H., Darwanto, A., Neidigh, J. W. & Sowers, L. C., Dec 1 2009, In: Biochemistry. 48, 47, p. 11312-11318 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2008
Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells
McLean, L., Soto, U., Agama, K., Francis, J., Jimenez, R., Pommier, Y., Sowers, L. & Brantley, E., Apr 1 2008, In: International Journal of Cancer. 122, 7, p. 1665-1674 10 p.Research output: Contribution to journal › Article › peer-review
77 Scopus citations -
Characterization of synthetic oligonucleotides containing biologically important modified bases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Cui, Z., Theruvathu, J. A., Farrel, A., Burdzy, A. & Sowers, L. C., Aug 15 2008, In: Analytical Biochemistry. 379, 2, p. 196-207 12 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
Effect of mode of birth on purine and malondialdehyde in umbilical arterial plasma in normal term newborns
Calderon, T. C., Wu, W., Rawson, R. A., Sakala, E. P., Sowers, L. C., Boskovic, D. S. & Angeles, D. M., Jul 2008, In: Journal of Perinatology. 28, 7, p. 475-481 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Examination of hypochlorous acid-induced damage to cytosine residues in a CpG dinucleotide in DNA
Kang, J. I. & Sowers, L. C., Jun 2008, In: Chemical Research in Toxicology. 21, 6, p. 1211-1218 8 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
Mechanisms of base selection by the Escherichia coli mispaired uracil glycosylase
Liu, P., Theruvathu, J. A., Darwanto, A., Lao, V. V., Pascal, T., Goddard, W. & Sowers, L. C., Apr 4 2008, In: Journal of Biological Chemistry. 283, 14, p. 8829-8836 8 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Reduced brain injury in CD18-deficient mice after experimental intracerebral hemorrhage
Titova, E., Ostrowski, R. P., Kevil, C. G., Tong, W., Rojas, H., Sowers, L. C., Zhang, J. H. & Tang, J., 2008, In: Journal of Neuroscience Research. 86, 14, p. 3240-3245 6 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
2007
Effects of apocynin and ethanol on intracerebral haemorrhage-induced brain injury in rats
Titova, E., Ostrowski, R. P., Sowers, L. C., Zhang, J. H. & Tang, J., Sep 2007, In: Clinical and Experimental Pharmacology and Physiology. 34, 9, p. 845-850 6 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Elevated total peripheral leukocyte count may identify risk for neurological disability in asphyxiated term neonates
Morkos, A. A., Hopper, A. O., Deming, D. D., Yellon, S. M., Wycliffe, N., Ashwal, S., Sowers, L. C., Peverini, R. L. & Angeles, D. M., Jun 2007, In: Journal of Perinatology. 27, 6, p. 365-370 6 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations